Gene: TRPV5 (transient receptor potential cation channel, subfamily V, member 5)
Homo sapiens
Symbol:
TRPV5
Name:
transient receptor potential cation channel, subfamily V, member 5
Description:
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
calcium transport protein 2; calcium transporter 2; CAT2; ECaC; ECAC1; epithelial calcium channel 1; osm-9-like TRP channel 3; OTRPC3; OTTHUMP00000211572; OTTHUMP00000211602; transient receptor potential cation channel subfamily V member 5
Orthologs:
Mus musculus : Trpv5
(transient receptor potential cation channel, subfamily V, member 5)
MGI
Trpv5
(transient receptor potential cation channel, subfamily V, member 5)
Latest Assembly:
Human Genome Assembly GRCh37
Position:
Map Chr Position Strand Source Human Alternate Assembly CHM1_1 7 145,969,560 - 145,994,801 - NCBI Human Alternate Assembly CRA_TCAGchr7v2 7 142,007,517 - 142,032,689 - NCBI Human Genome Assembly HuRef 7 136,943,932 - 136,969,107 - NCBI Human Genome Assembly GRCh37 7 142,605,648 - 142,630,820 - NCBI Human Genome Assembly Build 36 7 142,315,770 - 142,340,942 - NCBI Human Cytogenetic Map 7 q35 NCBI Human Genome Assembly 7 142,122,103 - 142,147,742 NCBI
Model
Gene Ontology Annotations
Biological Process calcium ion transport ISS UniProtKB:P69744 2290271 GO_REF:0000024 UniProtKB GO_REF:0000024 calcium ion transport TAS 2290271 PMID:15665527 UniProtKB PMID:15665527 protein tetramerization ISS UniProtKB:P69744 2290271 GO_REF:0000024 UniProtKB GO_REF:0000024
1300014 BP48_H Blood pressure QTL 48 (human) 2.26 .00063 Blood pressure systolic 7 127750680 151567307 Human 1300016 BW18_H Body weight QTL 18 (human) 2.26 .0006 Body weight body mass index 7 103502803 143723868 Human 1300022 BW27_H Body weight QTL 27 (human) 1.29 Body weight body mass index 7 127012653 153012653 Human 2289223 SLEP9_H Serum leptin level QTL 9 (human) 1.77 .0022 Hormone level leptin 7 137699472 159121409 Human 1357389 BW68_H Body weight QTL 68 (human) .0011 Body weight body mass index 7 132279626 151567307 Human 1578613 SCL123_H Serum cholesterol level QTL 123 (human) 2.5 Lipid level triglyceride 7 140012565 151567307 Human 1578612 SCL122_H Serum cholesterol level QTL 122 (human) 1.8 Lipid level triglyceride-HDL ratio 7 132279626 151567307 Human 1578610 SCL128_H Serum cholesterol level QTL 128 (human) 2.2 Lipid level LDL cholesterol 7 140012742 156472993 Human 1559391 SCL109_H Serum cholesterol level QTL 109 (human) 1.86 Lipid level triglyceride 7 140012565 148544056 Human 1578618 SCL127_H Serum cholesterol level QTL 127 (human) 3.7 Lipid level triglyceride 7 140012742 156472993 Human 2289381 BW417_H Body weight QTL 417 (human) 3.1 .00008 Body weight 7 141407418 143602276 Human 1643511 BW256_H Body weight QTL 256 (human) 4.7 .00001 Body weight body mass index 7 119279769 145279769 Human 1643500 BW257_H Body weight QTL 257 (human) 3.2 .00007 Body weight body mass index 7 119279769 145279769 Human 1643497 BW258_H Body weight QTL 258 (human) 4.9 .00001 Body weight body mass index 7 119279769 145279769 Human 2289327 BW383_H Body weight QTL 383 (human) 2.53 .00032 Body fat amount abdominal 7 138567210 159121409 Human 1643378 BW315_H Body weight QTL 315 (human) 2.79 .0003 Body weight lean mass 7 130723768 156723768 Human 1643439 BW101_H Body weight QTL 101 (human) 1.97 .001 Body fat amount abdominal visceral 7 127750680 153750680 Human 2301161 PRSTS391_H Prostate tumor susceptibility QTL 391 (human) 1.67 Prostate tumor susceptibility 7 137624141 159121409 Human 2314594 INSUL13_H Insulin level QTL 13 (human) 3.21 .022266 Insulin level insulin resistance 7 138567210 159121409 Human 2314577 GLUCO59_H Glucose level QTL 59 (human) 2.31 .068 Glucose level fasting 7 138567210 159121409 Human 2314575 INSUL11_H Insulin level QTL 11 (human) 2.26 .057268 Insulin level fasting 7 138567210 159121409 Human
Gene Ontology Annotations
