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ONTOLOGY REPORT - ANNOTATIONS

Term:smoothened signaling pathway
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Accession:GO:0007224 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
Synonyms:exact_synonym: hedgehog signaling pathway;   smoothened signalling pathway
 narrow_synonym: Sonic hedgehog signaling pathway;   hh signaling pathway;   hh signalling pathway
 related_synonym: Shh signaling pathway
 xref: Wikipedia:Hedgehog_signaling_pathway


show annotations for term's descendants           Sort by:
smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Arl13b ARF like GTPase 13B involved_in ISO (PMID:17488627), (PMID:21976698) RGD PMID:17488627 PMID:21976698 NCBI chr11:150,100...217,103
Ensembl chr11:150,955...217,197 		JBrowse link
G Arl3 ARF like GTPase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21289087)		 Ensembl
RGD		 PMID:21289087 GO_REF:0000107 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820 		JBrowse link
G B9d1 B9 domain containing 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:22179047)		 UniProt
RGD		 PMID:22179047 GO_REF:0000024 NCBI chr10:46,186,222...46,196,309
Ensembl chr10:46,186,691...46,196,008 		JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within ISO MGI:98715 (PMID:22228099) RGD PMID:22228099 NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated acts_upstream_of_or_within ISO (PMID:16647303) RGD PMID:16647303 NCBI chr11:56,122,697...56,198,060
Ensembl chr11:56,122,750...56,198,059 		JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A acts_upstream_of_or_within
involved_in		 ISO MGI:5708063 (PMID:22179047), (PMID:24947469) RGD PMID:22179047 PMID:24947469 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of ISO (PMID:10981962) RGD PMID:10981962 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within		 IEA
ISO
IDA		 GO_REF:0000107
MGI:98297 (PMID:16647304)
PMID:16647303		 Ensembl
RGD		 PMID:16647304 PMID:16647303 GO_REF:0000107, RGD:8554425 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033 		JBrowse link
G Cfap410 cilia and flagella associated protein 410 acts_upstream_of_or_within ISO (PMID:21289087) RGD PMID:21289087 NCBI chr20:10,687,863...10,694,736
Ensembl chr20:10,687,863...10,694,737 		JBrowse link
G Chrd chordin involved_in ISO MGI:104327|MGI:1313268 (PMID:12397106) RGD PMID:12397106 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673 		JBrowse link
G Cluap1 clusterin associated protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:105373|MGI:4363468 (PMID:23351563), (PMID:23742838)		 Ensembl
RGD		 PMID:23351563 PMID:23742838 GO_REF:0000107 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711 		JBrowse link
G Cpap centrosome assembly and centriole elongation protein acts_upstream_of_or_within ISO MGI:2448985|MGI:4432238 (PMID:24706806) RGD PMID:24706806 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887372|MGI:6887373 (PMID:29038301) RGD PMID:29038301 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of ISO MGI:108075 (PMID:16543460) RGD PMID:16543460 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Dhh desert hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 TAS
ISO
IBA		 (PMID:25639508)
GO_REF:0000033		 RGD
GO_Central		 PMID:25639508 PMID:11118005 GO_REF:0000033, RGD:634737 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Disp1 dispatched RND transporter family member 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702 		JBrowse link
G Disp2 dispatched RND transporter family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:105,762,303...105,777,826
Ensembl chr 3:105,762,305...105,777,800 		JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in ISO (PMID:18455992) RGD PMID:18455992 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106 		JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:5557987 (PMID:23955340) RGD PMID:23955340 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066 		JBrowse link
G Dzip1l DAZ interacting zinc finger protein 1-like involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:6357158 (PMID:29487109)		 Ensembl
RGD		 PMID:29487109 GO_REF:0000107 NCBI chr 8:100,188,414...100,229,077
Ensembl chr 8:100,194,999...100,228,988 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:3785162 (PMID:32980560) RGD PMID:32980560 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Evc EvC ciliary complex subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099 		JBrowse link
G Evc2 EvC ciliary complex subunit 2 involved_in ISO (PMID:21356043) RGD PMID:21356043 NCBI chr14:73,366,832...73,454,539
Ensembl chr14:73,367,963...73,454,516 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:25053416), (PMID:29545125), (PMID:29700203) RGD PMID:25053416 PMID:29545125 PMID:29700203 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of ISO MGI:2135961 (PMID:16540513), (PMID:16778080) RGD PMID:16540513 PMID:16778080 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO MGI:3042750|MGI:98297 (PMID:15105374) RGD PMID:15105374 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1347476 (PMID:23383217)		 Ensembl
RGD		 PMID:23383217 GO_REF:0000107 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of ISO MGI:1347472 (PMID:23383217) RGD PMID:23383217 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO (PMID:11493558) RGD PMID:11493558 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of ISO MGI:2388397|MGI:3711070 (PMID:17504940), (PMID:17525797) RGD PMID:17504940 PMID:17525797 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:19878745), (PMID:31279575)
MGI:95728 (PMID:16571625), (PMID:18449196), (PMID:19124651), (PMID:23201751), (PMID:9769173)
GO_REF:0000033		 RGD
GO_Central		 PMID:9769173 PMID:16571625 PMID:18449196 PMID:19124651 PMID:19878745 More... GO_REF:0000033 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:15994174), (PMID:31279575)
MGI:1857509|MGI:2446434|MGI:3664541|MGI:3834146|MGI:95727 (PMID:16571625), (PMID:19056373), (PMID:19124651)
GO_REF:0000033		 RGD
GO_Central		 PMID:15994174 PMID:16571625 PMID:19056373 PMID:19124651 PMID:31279575 GO_REF:0000033 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within
involved_in		 TAS
ISO
IBA		 MGI:108075|MGI:96533|MGI:98297 (PMID:12435628), (PMID:16284117), (PMID:16396903), (PMID:16571630), (PMID:17043310)
MGI:106676 (PMID:22234993)
GO_REF:0000033
(PMID:31279575)		 RGD
GO_Central		 PMID:12435628 PMID:16284117 PMID:16396903 PMID:16571630 PMID:17043310 More... GO_REF:0000033, RGD:1303367 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Gpc2 glypican 2 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:20231458 GO_REF:0000033, RGD:5510027 NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208 		JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2159355 (PMID:19733558)		 Ensembl
RGD		 PMID:19733558 GO_REF:0000107 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of
involved_in		 ISO
IEA		 MGI:5439169 (PMID:24062445)
GO_REF:0000107		 RGD
Ensembl		 PMID:24062445 GO_REF:0000107 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:19124651)		 Ensembl
RGD		 PMID:19124651 GO_REF:0000107 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:19124651)		 UniProt
RGD		 PMID:19124651 GO_REF:0000024 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001 		JBrowse link
G Hhat hedgehog acyltransferase acts_upstream_of_or_within ISO MGI:3051900|MGI:3051901 (PMID:15075292) RGD PMID:15075292 NCBI chr13:104,024,507...104,283,580
Ensembl chr13:104,010,916...104,282,893 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:1314872 (PMID:16537918)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:16537918 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:1314872 (PMID:16537918) RGD PMID:16537918 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IDA RGD PMID:21720682 RGD:5510033 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Ift172 intraflagellar transport 172 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11062270)		 Ensembl
RGD		 PMID:11062270 GO_REF:0000107 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift20 intraflagellar transport 20 acts_upstream_of_or_within ISO (PMID:19654211) RGD PMID:19654211 NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124 		JBrowse link
G Ift25 intraflagellar transport 25 involved_in ISO
IBA		 (PMID:22595669)
GO_REF:0000033		 RGD
GO_Central		 PMID:22595669 GO_REF:0000033 NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421 		JBrowse link
G Ift27 intraflagellar transport 27 involved_in ISO (PMID:25446516) RGD PMID:25446516 NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416 		JBrowse link
G Ift46 intraflagellar transport 46 acts_upstream_of_or_within ISO (PMID:21289087) RGD PMID:21289087 NCBI chr 8:45,081,593...45,104,052
Ensembl chr 8:45,087,440...45,104,052 		JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (PMID:15930098) RGD PMID:15930098 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980 		JBrowse link
G Ift56 intraflagellar transport 56 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25340710), (PMID:28264835)		 UniProt
RGD		 PMID:25340710 PMID:28264835 GO_REF:0000024 NCBI chr 4:67,090,622...67,154,707
Ensembl chr 4:67,090,660...67,147,903 		JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO MGI:3707373 (PMID:17027958) RGD PMID:17027958 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812 		JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO MGI:3665440|MGI:3689350|MGI:3856827|MGI:5818514 (PMID:21227999), (PMID:23333501), (PMID:26098911), (PMID:26996322), (PMID:30683845), (PMID:32227389) RGD PMID:21227999 PMID:23333501 PMID:26098911 PMID:26996322 PMID:30683845 More... NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:2157527|MGI:2445832|MGI:3027342|MGI:3710185|MGI:3823090|MGI:98297 (PMID:15930098), (PMID:19036983), (PMID:19654211), (PMID:21429982), (PMID:22228099) RGD PMID:15930098 PMID:19036983 PMID:19654211 PMID:21429982 PMID:22228099 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:21537345)
(PMID:11517919)
MGI:104903 (PMID:19590577), (PMID:25639508)
GO_REF:0000033		 RGD
GO_Central		 PMID:11517919 PMID:19590577 PMID:21537345 PMID:25639508 GO_REF:0000033 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:4441401 (PMID:22935613)		 Ensembl
RGD		 PMID:22935613 GO_REF:0000107 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676 		JBrowse link
G Iqub IQ motif and ubiquitin domain containing acts_upstream_of_or_within ISO (PMID:21289087) RGD PMID:21289087 NCBI chr 4:52,931,768...52,993,795
Ensembl chr 4:52,931,767...52,993,834 		JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 acts_upstream_of ISO (PMID:16148242) RGD PMID:16148242 NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760 		JBrowse link
G Kiaa0586 KIAA0586 homolog involved_in IBA
ISO		 GO_REF:0000033
(PMID:21750036)		 GO_Central
RGD		 PMID:21750036 GO_REF:0000033 NCBI chr 6:89,622,711...89,725,951
Ensembl chr 6:89,623,699...89,725,962 		JBrowse link
G Kif3a kinesin family member 3a involved_in
acts_upstream_of_or_within		 ISO (PMID:27793670)
MGI:1861960|MGI:2179048|MGI:2386464 (PMID:18297065), (PMID:19286674)		 RGD PMID:18297065 PMID:19286674 PMID:27793670 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in ISO (PMID:18455992) RGD PMID:18455992 NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:82,955,207...82,974,084 		JBrowse link
G Megf8 multiple EGF-like-domains 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:32966817)
GO_REF:0000107		 RGD
Ensembl		 PMID:32966817 GO_REF:0000107 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613 		JBrowse link
G Mgrn1 mahogunin ring finger 1 acts_upstream_of_or_within ISO (PMID:32966817) RGD PMID:32966817 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Mosmo modulator of smoothened acts_upstream_of_or_within ISO (PMID:34486668) RGD PMID:34486668 NCBI chr 1:175,217,680...175,288,521
Ensembl chr 1:175,217,545...175,288,334 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:23201751) RGD PMID:23201751 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (PMID:18590716) RGD PMID:18590716 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411 		JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (PMID:18590716) RGD PMID:18590716 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681 		JBrowse link
G Nog noggin involved_in IEA
ISO		 GO_REF:0000107
MGI:104327|MGI:1313268 (PMID:12397106)		 Ensembl
RGD		 PMID:12397106 GO_REF:0000107 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like acts_upstream_of_or_within ISO MGI:105373 (PMID:17028112) RGD PMID:17028112 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18590716)		 Ensembl
RGD		 PMID:18590716 GO_REF:0000107 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP RGD PMID:11181516 RGD:2311195 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (PMID:24336288) RGD PMID:24336288 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of ISO MGI:98218 (PMID:11532916) RGD PMID:11532916 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866 		JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of ISO MGI:97712 (PMID:11532916) RGD PMID:11532916 NCBI chr 3:14,132,574...14,168,533
Ensembl chr 3:14,094,004...14,168,535 		JBrowse link
G Ptch1 patched 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptchd1 patched domain containing 1 involved_in ISO (PMID:20844286) RGD PMID:20844286 NCBI chr  X:39,681,910...39,733,416
Ensembl chr  X:39,681,910...39,733,519 		JBrowse link
G Ptpdc1 protein tyrosine phosphatase domain containing 1 acts_upstream_of_or_within ISO (PMID:21289087) RGD PMID:21289087 NCBI chr17:16,028,964...16,076,512
Ensembl chr17:16,049,382...16,076,512 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin acts_upstream_of_or_within ISO (PMID:34463328) RGD PMID:34463328 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1931018|MGI:3574761 (PMID:17257418)		 Ensembl
RGD		 PMID:17257418 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Ro60 Ro60, Y RNA binding protein acts_upstream_of_or_within ISO (PMID:21289087) RGD PMID:21289087 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO MGI:3793279 (PMID:20660756) RGD PMID:20660756 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:2176465 (PMID:15668330)		 Ensembl
RGD		 PMID:15668330 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of ISO MGI:109295 (PMID:19168674) RGD PMID:19168674 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705 		JBrowse link
G Sall3 spalt-like transcription factor 3 acts_upstream_of ISO MGI:1889585 (PMID:19168674) RGD PMID:19168674 NCBI chr18:74,406,066...74,425,974
Ensembl chr18:74,407,560...74,426,789 		JBrowse link
G Septin2 septin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20558667)		 UniProt
Ensembl
RGD		 PMID:20558667 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 ISO
IBA
ISS		 (PMID:17850284), (PMID:31279575)
MGI:108075|MGI:1857796|MGI:95728 (PMID:10340755), (PMID:10375501), (PMID:11118883), (PMID:16611981), (PMID:16880529), (PMID:17043310), (PMID:25639508), (PMID:8906787)
(PMID:11517919)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:8906787 PMID:10340755 PMID:10375501 PMID:11118883 PMID:11517919 More... GO_REF:0000024 GO_REF:0000033 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Shox2 SHOX homeobox 2 involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:3605739 (PMID:17481601)		 Ensembl
RGD		 PMID:17481601 GO_REF:0000107 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of ISO MGI:5300464 (PMID:21937600) RGD PMID:21937600 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
(PMID:11517919), (PMID:21177415), (PMID:21209331), (PMID:23831757), (PMID:27793670)
MGI:1934268|MGI:2176173|MGI:2176255|MGI:2176256|MGI:2445832|MGI:2684317|MGI:95729|MGI:98297 (PMID:15107405), (PMID:16136078), (PMID:16571625), (PMID:17043310), (PMID:17199044), (PMID:19286674), (PMID:20185815), (PMID:29487109), (PMID:35353806)
GO_REF:0000033
GO_REF:0000107
(PMID:17850284), (PMID:19304771), (PMID:21177415), (PMID:32413283), (PMID:36202993), (PMID:9422511)		 UniProt
RGD
GO_Central
Ensembl		 PMID:9422511 PMID:11517919 PMID:15107405 PMID:16136078 PMID:16571625 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Stil STIL, centriolar assembly protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2152962 (PMID:10385121)		 GO_Central
RGD		 PMID:10385121 GO_REF:0000033 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Stk36 serine/threonine kinase 36 involved_in ISO
IBA		 (PMID:31279575)
GO_REF:0000033
(PMID:18600476)		 RGD
GO_Central		 PMID:18600476 PMID:31279575 GO_REF:0000033 NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_negative_effect ISO MGI:4461193 (PMID:29487109)
MGI:3619046 (PMID:16459298)		 RGD PMID:16459298 PMID:29487109 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:4127851|MGI:4440463 (PMID:20159594) RGD PMID:20159594 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
G Tctn2 tectonic family member 2 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:21565611)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:21565611 GO_REF:0000024 GO_REF:0000033 NCBI chr12:31,982,440...32,007,242
Ensembl chr12:31,822,733...32,007,069 		JBrowse link
G Tctn3 tectonic family member 3 involved_in ISO (PMID:22883145) RGD PMID:22883145 NCBI chr 1:239,414,003...239,425,273
Ensembl chr 1:239,415,203...239,425,272 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2384513 (PMID:18990706)		 Ensembl
RGD		 PMID:18990706 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tmem17 transmembrane protein 17 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:22179047)		 UniProt
RGD		 PMID:22179047 GO_REF:0000024 NCBI chr14:96,483,648...96,524,238
Ensembl chr14:96,518,793...96,524,233 		JBrowse link
G Tmem231 transmembrane protein 231 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
(PMID:22179047)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22179047 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,883,077...39,904,296
Ensembl chr19:39,883,077...39,904,269 		JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (PMID:23141541) RGD PMID:23141541 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544|MGI:2179048|MGI:5587034 (PMID:18327258), (PMID:29615573) RGD PMID:18327258 PMID:29615573 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903 		JBrowse link
G Tuba1a tubulin, alpha 1A involved_in ISO (PMID:27793670) RGD PMID:27793670 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of ISO MGI:3664273 (PMID:19223390) RGD PMID:19223390 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO (PMID:31279575) RGD PMID:31279575 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467 		JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:34463328) RGD PMID:34463328 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924 		JBrowse link
G Wdpcp WD repeat containing planar cell polarity effector involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5558098 (PMID:24302887)		 Ensembl
RGD		 PMID:24302887 GO_REF:0000107 NCBI chr14:95,645,955...95,977,120
Ensembl chr14:95,646,038...95,977,113 		JBrowse link
G Wdr19 WD repeat domain 19 acts_upstream_of_or_within ISO MGI:5315747|MGI:5315748 (PMID:22228095) RGD PMID:22228095 NCBI chr14:43,042,474...43,106,337
Ensembl chr14:43,042,478...43,106,288 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:17284610) RGD PMID:17284610 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of ISO MGI:3701350 (PMID:16818445) RGD PMID:16818445 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133 		JBrowse link
G Zfp423 zinc finger protein 423 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:27727273)		 Ensembl
RGD		 PMID:27727273 GO_REF:0000107 NCBI chr19:19,111,213...19,407,373
Ensembl chr19:19,110,238...19,407,373 		JBrowse link
G Zic3 Zic family member 3 involved_in ISO MGI:95729 (PMID:22234993) RGD PMID:22234993 NCBI chr  X:136,123,662...136,129,627
Ensembl chr  X:136,124,026...136,134,746 		JBrowse link
mesenchymal smoothened signaling pathway involved in prostate gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12221011)		 Ensembl
RGD		 PMID:12221011 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
negative regulation of hh target transcription factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30111653)		 UniProt
RGD		 PMID:30111653 GO_REF:0000024 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
negative regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:10981962) RGD PMID:10981962 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:108075|MGI:99833 (PMID:28817564) RGD PMID:28817564 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (PMID:9811582) RGD PMID:9811582 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:11572986) RGD PMID:11572986 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1932386 (PMID:28778798) RGD PMID:28778798 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:19667090) RGD PMID:19667090 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Glis2 GLIS family zinc finger 2 involved_in ISO (PMID:21816948) RGD PMID:21816948 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578 		JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 GO_REF:0000024
MGI:2159356|MGI:96533 (PMID:18477453), (PMID:19590577)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18477453 PMID:19590577 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:5439169 (PMID:24062445)
GO_REF:0000107		 RGD
Ensembl		 PMID:24062445 GO_REF:0000107 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421 		JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 involved_in ISO (PMID:31010679) RGD PMID:31010679 NCBI chr20:25,329,972...25,404,657
Ensembl chr20:25,330,280...25,404,657 		JBrowse link
G Hhip Hedgehog-interacting protein acts_upstream_of_or_within
involved_in		 ISO MGI:2450891 (PMID:10050855), (PMID:12569124)
(PMID:15294024)		 RGD PMID:10050855 PMID:12569124 PMID:15294024 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528 		JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within
involved_in		 ISO MGI:3578529|MGI:95728 (PMID:28778798)
(PMID:21209331)		 RGD PMID:21209331 PMID:28778798 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Ift172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2682066 (PMID:28778798)		 Ensembl
RGD		 PMID:28778798 GO_REF:0000107 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 acts_upstream_of_or_within ISO (PMID:16148242) RGD PMID:16148242 NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760 		JBrowse link
G Kctd21 potassium channel tetramerization domain containing 21 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr 1:151,650,074...151,669,775
Ensembl chr 1:151,650,104...151,667,645 		JBrowse link
G Kctd6 potassium channel tetramerization domain containing 6 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr15:16,695,297...16,712,460
Ensembl chr15:16,695,297...16,698,699 		JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (PMID:19549984), (PMID:19592253), (PMID:19666503) RGD PMID:19549984 PMID:19592253 PMID:19666503 NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576 		JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:29290584)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:29290584 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613 		JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29290584)		 UniProt
RGD		 PMID:29290584 GO_REF:0000024 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315 		JBrowse link
G Mir29a microRNA 29a IDA RGD PMID:32544883 RGD:243065126 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir9 microRNA 9 IDA RGD PMID:32544883 RGD:243065126 NCBI chr 9:1,080,274...1,080,383
Ensembl chr 9:1,080,274...1,080,383 		JBrowse link
G Mosmo modulator of smoothened involved_in ISO (PMID:29290584) RGD PMID:29290584 NCBI chr 1:175,217,680...175,288,521
Ensembl chr 1:175,217,545...175,288,334 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97760 (PMID:22007132)		 Ensembl
RGD		 PMID:22007132 GO_REF:0000107 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:97592 (PMID:22007132)		 Ensembl
RGD		 PMID:22007132 GO_REF:0000107 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Ptch1 patched 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857447|MGI:2142166|MGI:2153143 (PMID:11493558), (PMID:11784021), (PMID:19004860), (PMID:19684112), (PMID:19809516), (PMID:9006067)
UniProtKB:Q62226 (PMID:21931618)		 GO_Central
RGD		 PMID:9006067 PMID:11493558 PMID:11784021 PMID:19004860 PMID:19684112 More... GO_REF:0000033 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:32467643) RGD PMID:32467643 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1931018|MGI:3574761 (PMID:17257418)		 Ensembl
RGD		 PMID:17257418 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (PMID:19887680) RGD PMID:19887680 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176465 (PMID:15668330)		 Ensembl
RGD		 PMID:15668330 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:109295 (PMID:19168674) RGD PMID:19168674 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705 		JBrowse link
G Sall3 spalt-like transcription factor 3 acts_upstream_of_or_within ISO MGI:1889585 (PMID:19168674) RGD PMID:19168674 NCBI chr18:74,406,066...74,425,974
Ensembl chr18:74,407,560...74,426,789 		JBrowse link
G Serpine2 serpin family E member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:98297 (PMID:17409116)		 Ensembl
RGD		 PMID:17409116 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:27234298), (PMID:28965847)
GO_REF:0000033
MGI:3619046|MGI:4840420 (PMID:16459298), (PMID:18488998), (PMID:19684112)		 RGD
GO_Central		 PMID:16459298 PMID:18488998 PMID:19684112 PMID:27234298 PMID:28965847 GO_REF:0000033 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:35353806)		 Ensembl
RGD		 PMID:35353806 GO_REF:0000107 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (PMID:21945076) RGD PMID:21945076 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977 		JBrowse link
G Tulp3 TUB like protein 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:20889716)
MGI:2388066|MGI:3664273 (PMID:19223390), (PMID:19286674), (PMID:19334287)		 RGD PMID:19223390 PMID:19286674 PMID:19334287 PMID:20889716 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27299863), (PMID:33819267)		 UniProt
RGD		 PMID:27299863 PMID:33819267 GO_REF:0000024 NCBI chr 7:69,115,216...69,224,843
Ensembl chr 7:69,116,761...69,224,903 		JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS		 (PMID:20643644)
GO_REF:0000024		 RGD
UniProt		 PMID:20643644 GO_REF:0000024 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467 		JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:23747190) RGD PMID:23747190 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571 		JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:10781055) RGD PMID:10781055 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr161 G protein-coupled receptor 161 involved_in ISO (PMID:23332756) RGD PMID:23332756 NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613 		JBrowse link
positive regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Armc9 armadillo repeat containing 9 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:29459677)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29459677 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:86,802,868...86,928,860 		JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within ISO MGI:5007063 (PMID:22280990) RGD PMID:22280990 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601 		JBrowse link
G Cibar1 CBY1 interacting BAR domain containing 1 involved_in ISO (PMID:29459677) RGD PMID:29459677 NCBI chr 5:25,613,993...25,632,440
Ensembl chr 5:25,614,033...25,632,489 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:108075 (PMID:16543460) RGD PMID:16543460 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Dcdc2 doublecortin domain containing 2 involved_in ISO (PMID:21698230) RGD PMID:21698230 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743 		JBrowse link
G Dhh desert hedgehog signaling molecule involved_in ISO (PMID:24342078)
(PMID:33063110)		 RGD PMID:24342078 PMID:33063110 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (PMID:25644602) RGD PMID:25644602 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837 		JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4359237 (PMID:18488998)		 Ensembl
RGD		 PMID:18488998 GO_REF:0000107 NCBI chr 8:4,189,067...4,412,183
Ensembl chr 8:4,189,257...4,412,183 		JBrowse link
G Evc EvC ciliary complex subunit 1 involved_in ISO (PMID:17660199) RGD PMID:17660199 NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099 		JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961 (PMID:16540513), (PMID:16778080) RGD PMID:16540513 PMID:16778080 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1347476 (PMID:23383217)		 Ensembl
RGD		 PMID:23383217 GO_REF:0000107 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO MGI:1347472 (PMID:23383217) RGD PMID:23383217 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO MGI:2388397|MGI:3711070 (PMID:17504940), (PMID:17525797) RGD PMID:17504940 PMID:17525797 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gas8 growth arrest specific 8 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21659505)		 UniProt
RGD		 PMID:21659505 GO_REF:0000024 NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305 		JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:17035233) RGD PMID:17035233 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gorab golgin, RAB6-interacting involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:26967474)		 Ensembl
RGD		 PMID:26967474 GO_REF:0000107 NCBI chr13:75,745,678...75,762,307
Ensembl chr13:75,745,680...75,762,298 		JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2159355 (PMID:19733558)		 Ensembl
RGD		 PMID:19733558 GO_REF:0000107 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Ift172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2682066 (PMID:18488998)		 Ensembl
RGD		 PMID:18488998 GO_REF:0000107 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (PMID:24342078) RGD PMID:24342078 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4441401 (PMID:22935613)		 Ensembl
RGD		 PMID:22935613 GO_REF:0000107 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676 		JBrowse link
G Isl1 ISL LIM homeobox 1 IDA RGD PMID:32544883 RGD:243065126 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (PMID:19549984), (PMID:19666503) RGD PMID:19549984 PMID:19666503 NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:98297 (PMID:16020517) RGD PMID:16020517 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191 		JBrowse link
G Pdcl phosducin like involved_in ISS
ISO		 GO_REF:0000024
(PMID:29290584)		 UniProt
RGD		 PMID:29290584 GO_REF:0000024 NCBI chr 3:21,110,165...21,119,763
Ensembl chr 3:21,110,167...21,119,715
Ensembl chr 3:21,110,167...21,119,715 		JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of_or_within ISO MGI:98218 (PMID:11532916) RGD PMID:11532916 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866 		JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of_or_within ISO MGI:97712 (PMID:11532916) RGD PMID:11532916 NCBI chr 3:14,132,574...14,168,533
Ensembl chr 3:14,094,004...14,168,535 		JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in ISS
ISO		 GO_REF:0000024
(PMID:29290584)		 UniProt
RGD		 PMID:29290584 GO_REF:0000024 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538 		JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 acts_upstream_of_or_within ISO (PMID:25639508) RGD PMID:25639508 NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940 		JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO (PMID:25639508) RGD PMID:25639508 NCBI chr 1:163,831,876...163,899,925
Ensembl chr 1:163,832,015...163,899,393 		JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 acts_upstream_of_or_within ISO (PMID:25639508) RGD PMID:25639508 NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:17035233)
GO_REF:0000107		 RGD
Ensembl		 PMID:17035233 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19561609), (PMID:24342078)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19561609 PMID:24342078 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Shox2 SHOX homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3605739 (PMID:17481601)		 Ensembl
RGD		 PMID:17481601 GO_REF:0000107 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (PMID:21937600) RGD PMID:21937600 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16459297)		 Ensembl
RGD		 PMID:16459297 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Stk36 serine/threonine kinase 36 involved_in ISO (PMID:18600476) RGD PMID:18600476 NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422 		JBrowse link
G Tedc1 tubulin epsilon and delta complex 1 involved_in ISO (PMID:29459677) RGD PMID:29459677 NCBI chr 6:132,234,764...132,245,164
Ensembl chr 6:132,236,925...132,244,928 		JBrowse link
G Tedc2 tubulin epsilon and delta complex 2 involved_in ISO (PMID:29459677) RGD PMID:29459677 NCBI chr10:13,246,032...13,251,196
Ensembl chr10:13,246,037...13,251,124 		JBrowse link
G Ttc23 tetratricopeptide repeat domain 23 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:29459677)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29459677 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:121,245,996...121,329,500
Ensembl chr 1:121,248,084...121,329,494 		JBrowse link
G Tubd1 tubulin, delta 1 involved_in ISO (PMID:29290584) RGD PMID:29290584 NCBI chr10:71,367,936...71,391,387
Ensembl chr10:71,368,133...71,391,266 		JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29459677)		 UniProt
RGD		 PMID:29459677 GO_REF:0000024 NCBI chr17:8,898,074...8,910,538
Ensembl chr17:8,845,084...8,910,539
Ensembl chr 7:8,845,084...8,910,539 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:28992318) RGD PMID:28992318 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS		 (PMID:19878745), (PMID:20643644)
GO_REF:0000024		 RGD
UniProt		 PMID:19878745 PMID:20643644 GO_REF:0000024 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467 		JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350 (PMID:16818445) RGD PMID:16818445 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133 		JBrowse link
regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actrt1 actin-related protein T1 involved_in ISO
ISS		 (PMID:28869610)
GO_REF:0000024		 RGD
UniProt		 PMID:28869610 GO_REF:0000024 NCBI chr  X:125,584,102...125,585,455
Ensembl chr  X:125,584,065...125,585,457 		JBrowse link
G Arl6 ARF like GTPase 6 acts_upstream_of_or_within ISO MGI:5310744 (PMID:22139371) RGD PMID:22139371 NCBI chr11:40,711,878...40,738,254
Ensembl chr11:40,712,022...40,737,937 		JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO MGI:105373|MGI:99833 (PMID:19004860) RGD PMID:19004860 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520 		JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (PMID:28817564) RGD PMID:28817564 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826 		JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887372|MGI:6887373 (PMID:29038301) RGD PMID:29038301 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508 		JBrowse link
G Efcab7 EF-hand calcium binding domain 7 involved_in ISO (PMID:24582806) RGD PMID:24582806 NCBI chr 5:114,525,403...114,576,130
Ensembl chr 5:114,525,167...114,576,129 		JBrowse link
G Fbxl17 F-box and leucine-rich repeat protein 17 involved_in ISO (PMID:27234298) RGD PMID:27234298 NCBI chr 9:102,780,573...103,206,978
Ensembl chr 9:102,782,440...103,208,950 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:1927833 (PMID:15958512), (PMID:16618415) RGD PMID:15958512 PMID:16618415 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (PMID:16618415) RGD PMID:16618415 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fuz fuzzy planar cell polarity protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:19767740), (PMID:20962855), (PMID:21935430), (PMID:23806618)
MGI:4346364 (PMID:19877275)		 UniProt
RGD		 PMID:19767740 PMID:19877275 PMID:20962855 PMID:21935430 PMID:23806618 GO_REF:0000024 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530 		JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:19478089) RGD PMID:19478089 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2145349 (PMID:28817564) RGD PMID:28817564 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2145349 (PMID:28817564) RGD PMID:28817564 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ift140 intraflagellar transport 140 acts_upstream_of_or_within ISO MGI:4458412 (PMID:24009529) RGD PMID:24009529 NCBI chr10:14,032,665...14,121,682
Ensembl chr10:14,032,648...14,120,433 		JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO MGI:4821824 (PMID:21653639) RGD PMID:21653639 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift81 intraflagellar transport 81 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27666822)		 UniProt
RGD		 PMID:27666822 GO_REF:0000024 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057 		JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:20067783)
(PMID:25774014)		 UniProt
RGD		 PMID:20067783 PMID:25774014 GO_REF:0000024 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676 		JBrowse link
G Iqce IQ motif containing E involved_in ISO (PMID:24582806) RGD PMID:24582806 NCBI chr12:13,943,290...13,982,708
Ensembl chr12:13,943,487...13,982,693 		JBrowse link
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4433029|MGI:4887578 (PMID:21045211), (PMID:23454480)		 Ensembl
RGD		 PMID:21045211 PMID:23454480 GO_REF:0000107 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655 		JBrowse link
G Ptch1 patched 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2142166 (PMID:19004860) RGD PMID:19004860 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927 		JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (PMID:14687547) RGD PMID:14687547 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rpgrip1l Rpgrip1-like acts_upstream_of_or_within ISO MGI:3716208 (PMID:17553904) RGD PMID:17553904 NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083 		JBrowse link
G Tctn1 tectonic family member 1 acts_upstream_of_or_within ISO MGI:3716885 (PMID:16357211) RGD PMID:16357211 NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267 		JBrowse link
G Ttbk2 tau tubulin kinase 2 acts_upstream_of_or_within ISO MGI:5496675 (PMID:23141541) RGD PMID:23141541 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544 (PMID:19732765) RGD PMID:19732765 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (PMID:19286674) RGD PMID:19286674 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Wdr11 WD repeat domain 11 involved_in ISO (PMID:29263200) RGD PMID:29263200 NCBI chr 1:184,165,260...184,210,834
Ensembl chr 1:184,165,571...184,210,846 		JBrowse link
G Zic1 Zic family member 1 involved_in ISO UniProtKB:P47806 (PMID:11238441) RGD PMID:11238441 NCBI chr 8:91,908,548...91,918,020
Ensembl chr 8:91,908,576...91,912,731 		JBrowse link
smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2442827|MGI:95729 (PMID:17395647), (PMID:20159594) RGD PMID:17395647 PMID:20159594 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2442827|MGI:95728 (PMID:17395647), (PMID:20159594) RGD PMID:17395647 PMID:20159594 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within ISO MGI:2443231 (PMID:22689656) RGD PMID:22689656 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (PMID:20159594) RGD PMID:20159594 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415 		JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:3664273 (PMID:19223390) RGD PMID:19223390 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149 		JBrowse link
G Wdr19 WD repeat domain 19 acts_upstream_of_or_within ISO MGI:1932386|MGI:5315748 (PMID:22689656) RGD PMID:22689656 NCBI chr14:43,042,474...43,106,337
Ensembl chr14:43,042,478...43,106,288 		JBrowse link
smoothened signaling pathway involved in lung development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (PMID:28859094) RGD PMID:28859094 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4821832 (PMID:27340223)		 Ensembl
RGD		 PMID:27340223 GO_REF:0000107 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655 		JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (PMID:15215207) RGD PMID:15215207 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (PMID:15215207) RGD PMID:15215207 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (PMID:19684112) RGD PMID:19684112 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (PMID:15215207) RGD PMID:15215207 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (PMID:15215207) RGD PMID:15215207 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (PMID:19684112) RGD PMID:19684112 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20228
    cellular process 19289
      signal transduction 7199
        cell surface receptor signaling pathway 2842
          smoothened signaling pathway 172
            ciliary receptor clustering involved in smoothened signaling pathway 0
            mesenchymal smoothened signaling pathway involved in prostate gland development 1
            negative regulation of smoothened signaling pathway + 43
            positive regulation of smoothened signaling pathway + 46
            regulation of smoothened signaling pathway + 104
            smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 7
            smoothened signaling pathway involved in lung development 1
            smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 0
            smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
            smoothened signaling pathway involved in ventral spinal cord patterning + 3
Path 2
Term Annotations click to browse term
  biological_process 20228
    biological regulation 13626
      regulation of biological process 13203
        signaling 7760
          signal transduction 7199
            cell surface receptor signaling pathway 2842
              smoothened signaling pathway 172
                ciliary receptor clustering involved in smoothened signaling pathway 0
                mesenchymal smoothened signaling pathway involved in prostate gland development 1
                negative regulation of smoothened signaling pathway + 43
                positive regulation of smoothened signaling pathway + 46
                regulation of smoothened signaling pathway + 104
                smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 7
                smoothened signaling pathway involved in lung development 1
                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 0
                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
                smoothened signaling pathway involved in ventral spinal cord patterning + 3
paths to the root