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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of smoothened signaling pathway
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Accession:GO:0008589 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of smoothened signaling.
Synonyms:exact_synonym: regulation of hedgehog signaling pathway;   regulation of hh signaling pathway;   regulation of smoothened signalling pathway
 related_synonym: regulation of smoothened activity;   regulation of smoothened by patched;   regulation of smoothened receptor activity by patched
 alt_id: GO:0007226;   GO:0043109



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regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actrt1 actin-related protein T1 involved_in ISO
ISS
(PMID:28869610)
GO_REF:0000024
RGD
UniProt
PMID:28869610 GO_REF:0000024 NCBI chr  X:125,584,102...125,585,455 JBrowse link
G Arl6 ARF like GTPase 6 acts_upstream_of_or_within ISO MGI:5310744 (PMID:22139371) RGD PMID:22139371 NCBI chr11:40,711,878...40,738,254 JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO MGI:105373|MGI:99833 (PMID:19004860) RGD PMID:19004860 NCBI chr 1:164,127,304...164,225,088 JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (PMID:28817564) RGD PMID:28817564 NCBI chr17:706,863...717,828 JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887372|MGI:6887373 (PMID:29038301) RGD PMID:29038301 NCBI chr 5:153,515,507...153,516,455 JBrowse link
G Efcab7 EF-hand calcium binding domain 7 involved_in ISO (PMID:24582806) RGD PMID:24582806 NCBI chr 5:119,640,841...119,691,566 JBrowse link
G Fbxl17 F-box and leucine-rich repeat protein 17 involved_in ISO (PMID:27234298) RGD PMID:27234298 NCBI chr 9:102,780,573...103,206,978 JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:1927833 (PMID:15958512), (PMID:16618415) RGD PMID:15958512 PMID:16618415 NCBI chr 2:50,801,171...50,878,218 JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (PMID:16618415) RGD PMID:16618415 NCBI chr 1:194,175,703...194,280,914 JBrowse link
G Fuz fuzzy planar cell polarity protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:19767740), (PMID:20962855), (PMID:21935430), (PMID:23806618)
MGI:4346364 (PMID:19877275)
UniProt
RGD
PMID:19767740 PMID:19877275 PMID:20962855 PMID:21935430 PMID:23806618 GO_REF:0000024 NCBI chr 1:95,379,542...95,384,532 JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (PMID:19478089) RGD PMID:19478089 NCBI chr17:4,487,716...4,490,701 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2145349 (PMID:28817564) RGD PMID:28817564 NCBI chr13:29,946,882...30,163,589 JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2145349 (PMID:28817564) RGD PMID:28817564 NCBI chr17:54,134,064...54,405,198 JBrowse link
G Ift140 intraflagellar transport 140 acts_upstream_of_or_within ISO MGI:4458412 (PMID:24009529) RGD PMID:24009529 NCBI chr10:14,537,134...14,624,926 JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO MGI:4821824 (PMID:21653639) RGD PMID:21653639 NCBI chr 6:30,801,841...30,841,239 JBrowse link
G Ift81 intraflagellar transport 81 involved_in ISS
ISO
GO_REF:0000024
(PMID:27666822)
UniProt
RGD
PMID:27666822 GO_REF:0000024 NCBI chr12:33,957,744...34,037,164 JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:20067783)
(PMID:25774014)
UniProt
RGD
PMID:20067783 PMID:25774014 GO_REF:0000024 NCBI chr 2:125,528,965...125,613,295 JBrowse link
G Iqce IQ motif containing E involved_in ISO (PMID:24582806) RGD PMID:24582806 NCBI chr12:13,943,290...13,982,708 JBrowse link
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4433029|MGI:4887578 (PMID:21045211), (PMID:23454480)
Ensembl
RGD
PMID:21045211 PMID:23454480 GO_REF:0000107 NCBI chr10:73,152,599...73,167,451 JBrowse link
G Ptch1 patched 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:1,548,449...1,613,461 JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2142166 (PMID:19004860) RGD PMID:19004860 NCBI chr 9:35,943,522...35,967,367 JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (PMID:14687547) RGD PMID:14687547 NCBI chr 8:78,182,710...78,915,730 JBrowse link
G Rpgrip1l Rpgrip1-like acts_upstream_of_or_within ISO MGI:3716208 (PMID:17553904) RGD PMID:17553904 NCBI chr19:31,865,050...31,957,930 JBrowse link
G Tctn1 tectonic family member 1 acts_upstream_of_or_within ISO MGI:3716885 (PMID:16357211) RGD PMID:16357211 NCBI chr12:39,970,554...40,003,727 JBrowse link
G Ttbk2 tau tubulin kinase 2 acts_upstream_of_or_within ISO MGI:5496675 (PMID:23141541) RGD PMID:23141541 NCBI chr 3:128,144,851...128,256,630 JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544 (PMID:19732765) RGD PMID:19732765 NCBI chr 3:71,269,425...71,343,936 JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (PMID:19286674) RGD PMID:19286674 NCBI chr 4:161,590,478...161,632,244 JBrowse link
G Wdr11 WD repeat domain 11 involved_in ISO (PMID:29263200) RGD PMID:29263200 NCBI chr 1:184,165,260...184,210,834 JBrowse link
G Zic1 Zic family member 1 involved_in ISO UniProtKB:P47806 (PMID:11238441) RGD PMID:11238441 NCBI chr 8:100,785,282...100,797,716 JBrowse link
negative regulation of hh target transcription factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:30111653)
UniProt
RGD
PMID:30111653 GO_REF:0000024 NCBI chr 1:22,518,051...22,583,044 JBrowse link
negative regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:10981962) RGD PMID:10981962 NCBI chr 8:54,200,617...54,211,770 JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:108075|MGI:99833 (PMID:28817564) RGD PMID:28817564 NCBI chr17:706,863...717,828 JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (PMID:9811582) RGD PMID:9811582 NCBI chr14:81,211,800...81,227,215 JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:11572986) RGD PMID:11572986 NCBI chr17:4,487,716...4,490,701 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1932386 (PMID:28778798) RGD PMID:28778798 NCBI chr13:29,946,882...30,163,589 JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:19667090) RGD PMID:19667090 NCBI chr17:54,134,064...54,405,198 JBrowse link
G Glis2 GLIS family zinc finger 2 involved_in ISO (PMID:21816948) RGD PMID:21816948 NCBI chr10:11,457,594...11,484,948 JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:2159356|MGI:96533 (PMID:18477453), (PMID:19590577)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18477453 PMID:19590577 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:136,789,770...137,157,598 JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:5439169 (PMID:24062445)
GO_REF:0000107
RGD
Ensembl
PMID:24062445 GO_REF:0000107 NCBI chr13:46,598,574...46,605,421 JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 involved_in ISO (PMID:31010679) RGD PMID:31010679 NCBI chr20:25,329,972...25,404,657 JBrowse link
G Hhip Hedgehog-interacting protein acts_upstream_of_or_within
involved_in
ISO MGI:2450891 (PMID:10050855), (PMID:12569124)
(PMID:15294024)
RGD PMID:10050855 PMID:12569124 PMID:15294024 NCBI chr19:27,863,684...27,952,528 JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within
involved_in
ISO MGI:3578529|MGI:95728 (PMID:28778798)
(PMID:21209331)
RGD PMID:21209331 PMID:28778798 NCBI chr 4:148,905,031...148,975,458 JBrowse link
G Ift172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2682066 (PMID:28778798)
Ensembl
RGD
PMID:28778798 GO_REF:0000107 NCBI chr 6:30,801,841...30,841,239 JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 acts_upstream_of_or_within ISO (PMID:16148242) RGD PMID:16148242 NCBI chr10:54,602,575...54,604,738 JBrowse link
G Kctd21 potassium channel tetramerization domain containing 21 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr 1:151,650,074...151,669,775 JBrowse link
G Kctd6 potassium channel tetramerization domain containing 6 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr15:16,695,297...16,712,460 JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (PMID:19549984), (PMID:19592253), (PMID:19666503) RGD PMID:19549984 PMID:19592253 PMID:19666503 NCBI chr 1:143,041,206...143,067,873 JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:29290584)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:29290584 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:80,902,236...80,951,614 JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 NCBI chr10:10,638,881...10,688,332 JBrowse link
G Mir29a microRNA 29a IDA RGD PMID:32544883 RGD:243065126 NCBI chr 4:60,617,955...60,618,042 JBrowse link
G Mir9 microRNA 9 IDA RGD PMID:32544883 RGD:243065126 NCBI chr 9:1,080,274...1,080,383 JBrowse link
G Mosmo modulator of smoothened involved_in ISO
IBA
(PMID:29290584)
GO_REF:0000033
RGD
GO_Central
PMID:29290584 GO_REF:0000033 NCBI chr 1:175,217,680...175,288,521 JBrowse link
G Ncoa2 nuclear receptor coactivator 2 involved_in ISO (PMID:39531503) RGD PMID:39531503 NCBI chr 5:5,835,642...6,069,693 JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97760 (PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 NCBI chr19:41,059,843...41,083,189 JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97592 (PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 NCBI chr 2:238,297,140...238,389,317 JBrowse link
G Ptch1 patched 1 involved_in
acts_upstream_of_or_within
ISO
IBA
UniProtKB:Q62226 (PMID:21931618)
GO_REF:0000033
MGI:1857447|MGI:2142166|MGI:2153143 (PMID:11493558), (PMID:11784021), (PMID:19004860), (PMID:19684112), (PMID:19809516), (PMID:9006067)
RGD
GO_Central
PMID:9006067 PMID:11493558 PMID:11784021 PMID:19004860 PMID:19684112 More... GO_REF:0000033 NCBI chr17:1,548,449...1,613,461 JBrowse link
G Ptch2 patched 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:130,571,956...130,592,506 JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:32467643) RGD PMID:32467643 NCBI chr10:33,668,560...33,676,031 JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1931018|MGI:3574761 (PMID:17257418)
Ensembl
RGD
PMID:17257418 GO_REF:0000107 NCBI chr15:54,780,858...54,911,989 JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (PMID:19887680) RGD PMID:19887680 NCBI chr 7:18,853,065...19,015,378 JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176465 (PMID:15668330)
Ensembl
RGD
PMID:15668330 GO_REF:0000107 NCBI chr 9:23,661,278...23,990,248 JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:109295 (PMID:19168674) RGD PMID:19168674 NCBI chr19:34,179,316...34,196,278 JBrowse link
G Sall3 spalt-like transcription factor 3 acts_upstream_of_or_within ISO MGI:1889585 (PMID:19168674) RGD PMID:19168674 NCBI chr18:74,406,066...74,425,974 JBrowse link
G Serpine2 serpin family E member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98297 (PMID:17409116)
Ensembl
RGD
PMID:17409116 GO_REF:0000107 NCBI chr 9:81,124,746...81,188,866 JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:27234298), (PMID:28965847)
GO_REF:0000033
MGI:3619046|MGI:4840420 (PMID:16459298), (PMID:18488998), (PMID:19684112)
RGD
GO_Central
PMID:16459298 PMID:18488998 PMID:19684112 PMID:27234298 PMID:28965847 GO_REF:0000033 NCBI chr 1:255,199,108...255,296,983 JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:35353806)
Ensembl
RGD
PMID:35353806 GO_REF:0000107 NCBI chr12:32,052,542...32,061,628 JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (PMID:21945076) RGD PMID:21945076 NCBI chr 9:99,521,176...99,557,966 JBrowse link
G Tulp3 TUB like protein 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20889716)
MGI:2388066|MGI:3664273 (PMID:19223390), (PMID:19286674), (PMID:19334287)
RGD PMID:19223390 PMID:19286674 PMID:19334287 PMID:20889716 NCBI chr 4:161,590,478...161,632,244 JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISS
ISO
GO_REF:0000024
(PMID:27299863), (PMID:33819267)
UniProt
RGD
PMID:27299863 PMID:33819267 GO_REF:0000024 NCBI chr 7:69,115,216...69,224,843 JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS
(PMID:20643644)
GO_REF:0000024
RGD
UniProt
PMID:20643644 GO_REF:0000024 NCBI chr 8:66,888,820...66,895,380 JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:23747190) RGD PMID:23747190 NCBI chr 5:62,005,984...62,025,387 JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:10781055) RGD PMID:10781055 NCBI chr 7:118,514,684...118,559,316 JBrowse link
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr161 G protein-coupled receptor 161 involved_in ISO (PMID:23332756) RGD PMID:23332756 NCBI chr13:77,578,257...77,623,661 JBrowse link
positive regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Armc9 armadillo repeat containing 9 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:29459677)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29459677 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:94,250,492...94,376,589 JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within ISO MGI:5007063 (PMID:22280990) RGD PMID:22280990 NCBI chr 1:119,689,626...119,750,711 JBrowse link
G Cibar1 CBY1 interacting BAR domain containing 1 involved_in ISO (PMID:29459677) RGD PMID:29459677 NCBI chr 5:25,613,993...25,632,440 JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:108075 (PMID:16543460) RGD PMID:16543460 NCBI chr18:26,728,246...26,860,911 JBrowse link
G Dcdc2 doublecortin domain containing 2 involved_in ISO (PMID:21698230) RGD PMID:21698230 NCBI chr17:40,274,009...40,459,757 JBrowse link
G Dhh desert hedgehog signaling molecule involved_in ISO (PMID:24342078)
(PMID:33063110)
RGD PMID:24342078 PMID:33063110 NCBI chr 7:130,050,910...130,056,406 JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (PMID:25644602) RGD PMID:25644602 NCBI chr15:75,786...209,735 JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4359237 (PMID:18488998)
Ensembl
RGD
PMID:18488998 GO_REF:0000107 NCBI chr 8:12,473,955...12,697,075 JBrowse link
G Evc EvC ciliary complex subunit 1 involved_in ISO (PMID:17660199) RGD PMID:17660199 NCBI chr14:77,680,901...77,722,608 JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961 (PMID:16540513), (PMID:16778080) RGD PMID:16540513 PMID:16778080 NCBI chr15:32,208,993...32,254,952 JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1347476 (PMID:23383217)
Ensembl
RGD
PMID:23383217 GO_REF:0000107 NCBI chr 6:75,099,907...75,136,534 JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO MGI:1347472 (PMID:23383217) RGD PMID:23383217 NCBI chr 3:135,470,123...135,474,326 JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO MGI:2388397|MGI:3711070 (PMID:17504940), (PMID:17525797) RGD PMID:17504940 PMID:17525797 NCBI chr17:4,487,716...4,490,701 JBrowse link
G Gas8 growth arrest specific 8 involved_in ISS
ISO
GO_REF:0000024
(PMID:21659505)
UniProt
RGD
PMID:21659505 GO_REF:0000024 NCBI chr19:51,552,770...51,572,323 JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:17035233) RGD PMID:17035233 NCBI chr 7:65,042,237...65,054,888 JBrowse link
G Gorab golgin, RAB6-interacting involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:26967474)
Ensembl
RGD
PMID:26967474 GO_REF:0000107 NCBI chr13:75,745,678...75,762,307 JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2159355 (PMID:19733558)
Ensembl
RGD
PMID:19733558 GO_REF:0000107 NCBI chr  X:136,789,770...137,157,598 JBrowse link
G Ift172 intraflagellar transport 172 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2682066 (PMID:18488998)
Ensembl
RGD
PMID:18488998 GO_REF:0000107 NCBI chr 6:30,801,841...30,841,239 JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (PMID:24342078) RGD PMID:24342078 NCBI chr 9:76,504,315...76,510,532 JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4441401 (PMID:22935613)
Ensembl
RGD
PMID:22935613 GO_REF:0000107 NCBI chr 2:125,528,965...125,613,295 JBrowse link
G Isl1 ISL LIM homeobox 1 IDA RGD PMID:32544883 RGD:243065126 NCBI chr 2:49,813,618...49,823,442 JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (PMID:19549984), (PMID:19666503) RGD PMID:19549984 PMID:19666503 NCBI chr 1:143,041,206...143,067,873 JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:98297 (PMID:16020517) RGD PMID:16020517 NCBI chr18:54,136,887...54,199,545 JBrowse link
G Pdcl phosducin like involved_in ISS
ISO
GO_REF:0000024
(PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 NCBI chr 3:41,519,953...41,529,545 JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:26,587,674...26,655,612 JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of_or_within ISO MGI:98218 (PMID:11532916) RGD PMID:11532916 NCBI chr13:78,136,783...78,205,379 JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of_or_within ISO MGI:97712 (PMID:11532916) RGD PMID:11532916 NCBI chr 3:14,132,574...14,168,533 JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in ISS
ISO
GO_REF:0000024
(PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 NCBI chr10:63,581,542...63,585,608 JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 acts_upstream_of_or_within ISO (PMID:25639508) RGD PMID:25639508 NCBI chr 7:114,759,016...114,880,995 JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO (PMID:25639508) RGD PMID:25639508 NCBI chr 1:163,831,876...163,899,925 JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 acts_upstream_of_or_within ISO (PMID:25639508) RGD PMID:25639508 NCBI chr20:6,200,891...6,232,848 JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:17035233)
GO_REF:0000107
RGD
Ensembl
PMID:17035233 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19561609), (PMID:24342078)
UniProt
Ensembl
RGD
PMID:19561609 PMID:24342078 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170 JBrowse link
G Shox2 SHOX homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3605739 (PMID:17481601)
Ensembl
RGD
PMID:17481601 GO_REF:0000107 NCBI chr 2:153,524,324...153,537,571 JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (PMID:21937600) RGD PMID:21937600 NCBI chr18:70,404,431...70,446,330 JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16459297)
Ensembl
RGD
PMID:16459297 GO_REF:0000107 NCBI chr 4:59,311,084...59,341,280 JBrowse link
G Stk36 serine/threonine kinase 36 involved_in ISO (PMID:18600476) RGD PMID:18600476 NCBI chr 9:83,625,905...83,652,785 JBrowse link
G Tedc1 tubulin epsilon and delta complex 1 involved_in ISO (PMID:29459677) RGD PMID:29459677 NCBI chr 6:132,234,764...132,245,164 JBrowse link
G Tedc2 tubulin epsilon and delta complex 2 involved_in ISO (PMID:29459677) RGD PMID:29459677 NCBI chr10:13,246,032...13,251,196 JBrowse link
G Ttc23 tetratricopeptide repeat domain 23 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:29459677)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29459677 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:121,245,996...121,329,500 JBrowse link
G Tubd1 tubulin, delta 1 involved_in ISO (PMID:29290584) RGD PMID:29290584 NCBI chr10:71,865,446...71,888,731 JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in ISS
ISO
GO_REF:0000024
(PMID:29459677)
UniProt
RGD
PMID:29459677 GO_REF:0000024 NCBI chr17:8,903,248...8,915,714 JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:28992318) RGD PMID:28992318 NCBI chr13:58,070,947...58,106,825 JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS
(PMID:19878745), (PMID:20643644)
GO_REF:0000024
RGD
UniProt
PMID:19878745 PMID:20643644 GO_REF:0000024 NCBI chr 8:66,888,820...66,895,380 JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350 (PMID:16818445) RGD PMID:16818445 NCBI chr10:44,094,140...44,121,134 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    regulation of biological process 13375
      regulation of response to stimulus 4324
        regulation of signal transduction 3279
          regulation of smoothened signaling pathway 106
            negative regulation of smoothened signaling pathway + 45
            positive regulation of smoothened signaling pathway + 46
            regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 1
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        signaling 7808
          signal transduction 7250
            cell surface receptor signaling pathway 2882
              smoothened signaling pathway 174
                regulation of smoothened signaling pathway 106
                  negative regulation of smoothened signaling pathway + 45
                  positive regulation of smoothened signaling pathway + 46
                  regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 1
paths to the root