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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of smoothened signaling pathway
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Accession:GO:0008589 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of smoothened signaling.
Synonyms:exact_synonym: regulation of hedgehog signaling pathway;   regulation of hh signaling pathway;   regulation of smoothened signalling pathway
 related_synonym: regulation of smoothened activity;   regulation of smoothened by patched;   regulation of smoothened receptor activity by patched
 alt_id: GO:0007226;   GO:0043109


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regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actrt1 actin-related protein T1 involved_in ISO
ISS
(PMID:28869610)
GO_REF:0000024
RGD
UniProt
PMID:28869610 GO_REF:0000024 NCBI chr  X:133,227,699...133,229,052
Ensembl chr  X:133,227,660...133,229,047
JBrowse link
G Arl6 ADP-ribosylation factor like GTPase 6 acts_upstream_of_or_within ISO MGI:5310744 (MGI:5306530|PMID:22139371) RGD PMID:22139371 MGI:5306530 NCBI chr11:42,858,476...42,884,324
Ensembl chr11:42,858,478...42,884,603
JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO MGI:105373|MGI:99833 (MGI:3821640|PMID:19004860) RGD PMID:19004860 MGI:3821640 NCBI chr 1:165,382,279...165,480,088
Ensembl chr 1:165,382,690...165,479,655
JBrowse link
G Fbxl17 F-box and leucine-rich repeat protein 17 involved_in ISO (PMID:27234298) RGD PMID:27234298 NCBI chr 9:110,515,558...110,936,631
Ensembl chr 9:110,515,558...110,936,631
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:1927833 (MGI:3588480|PMID:15958512), (MGI:3722952|PMID:16618415) RGD PMID:15958512 PMID:16618415 MGI:3588480 MGI:3722952 NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (MGI:3722952|PMID:16618415) RGD PMID:16618415 MGI:3722952 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fuz fuzzy planar cell polarity protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4438317|PMID:19767740), (MGI:5009776|PMID:20962855), (MGI:5296432|PMID:21935430), (MGI:5498583|PMID:23806618)
MGI:4346364 (MGI:4367921|PMID:19877275)
UniProt
RGD
PMID:19767740 PMID:19877275 PMID:20962855 PMID:21935430 PMID:23806618 GO_REF:0000024 MGI:4367921 MGI:4438317 MGI:5009776 MGI:5296432 MGI:5498583 NCBI chr 1:100,891,832...100,896,811
Ensembl chr 1:100,891,866...100,896,807
JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (MGI:4357747|PMID:19478089) RGD PMID:19478089 MGI:4357747 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Ift140 intraflagellar transport 140 acts_upstream_of_or_within ISO MGI:4458412 (MGI:5635784|PMID:24009529) RGD PMID:24009529 MGI:5635784 NCBI chr10:14,373,668...14,461,509
Ensembl chr10:14,373,679...14,461,160
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO MGI:4821824 (MGI:5285455|PMID:21653639) RGD PMID:21653639 MGI:5285455 NCBI chr 6:26,390,686...26,485,459 JBrowse link
G Ift81 intraflagellar transport 81 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:27666822)
UniProt
Ensembl
RGD
PMID:27666822 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,420,161...39,507,412
Ensembl chr12:39,423,596...39,506,890
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4441234|PMID:20067783)
(MGI:5644615|PMID:25774014)
UniProt
RGD
PMID:20067783 PMID:25774014 GO_REF:0000024 MGI:4441234 MGI:5644615 NCBI chr 2:127,459,089...127,521,327
Ensembl chr 2:127,459,012...127,525,437
JBrowse link
G Mks1 MKS transition zone complex subunit 1 acts_upstream_of_or_within ISO MGI:4433029|MGI:4887578 (MGI:4868517|PMID:21045211), (MGI:5487695|PMID:23454480) RGD PMID:21045211 PMID:23454480 MGI:4868517 MGI:5487695 NCBI chr10:75,149,814...75,160,481
Ensembl chr10:75,149,814...75,160,480
JBrowse link
G Ptch1 patched 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2142166 (MGI:3821640|PMID:19004860) RGD PMID:19004860 MGI:3821640 NCBI chr 9:38,469,784...38,496,185
Ensembl chr 9:38,470,298...38,495,176
JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (MGI:2683830|PMID:14687547) RGD PMID:14687547 MGI:2683830 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rpgrip1l Rpgrip1-like acts_upstream_of_or_within ISO MGI:3716208 (MGI:3715393|PMID:17553904) RGD PMID:17553904 MGI:3715393 NCBI chr19:17,115,266...17,208,055
Ensembl chr19:17,115,412...17,208,055
JBrowse link
G Tctn1 tectonic family member 1 acts_upstream_of_or_within ISO MGI:3716885 (MGI:3610767|PMID:16357211) RGD PMID:16357211 MGI:3610767 NCBI chr12:39,790,948...39,828,215
Ensembl chr12:39,790,965...39,824,064
JBrowse link
G Ttbk2 tau tubulin kinase 2 acts_upstream_of_or_within ISO MGI:5496675 (MGI:5493390|PMID:23141541) RGD PMID:23141541 MGI:5493390 NCBI chr 3:112,677,932...112,789,615
Ensembl chr 3:112,684,152...112,789,289
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544 (MGI:4367927|PMID:19732765) RGD PMID:19732765 MGI:4367927 NCBI chr 3:52,286,794...52,361,060
Ensembl chr 3:52,286,794...52,361,060
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3841503|PMID:19286674) RGD PMID:19286674 MGI:3841503 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link
G Wdr11 WD repeat domain 11 involved_in ISO (MGI:6116377|PMID:29263200) RGD PMID:29263200 MGI:6116377 NCBI chr 1:202,770,810...202,816,336
Ensembl chr 1:202,770,775...202,816,334
JBrowse link
G Zic1 Zic family member 1 involved_in ISO UniProtKB:P47806 (MGI:3688043|PMID:11238441) RGD PMID:11238441 MGI:3688043 NCBI chr 8:98,733,715...98,738,960
Ensembl chr 8:98,734,295...98,738,446
JBrowse link
negative regulation of hh target transcription factor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6220772|PMID:30111653)
UniProt
RGD
PMID:30111653 GO_REF:0000024 MGI:6220772 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
negative regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (MGI:1888832|PMID:10981962) RGD PMID:10981962 MGI:1888832 NCBI chr 8:49,297,604...49,309,370
Ensembl chr 8:49,297,608...49,308,806
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:1307032|PMID:9811582) RGD PMID:9811582 MGI:1307032 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (MGI:2150860|PMID:11572986) RGD PMID:11572986 MGI:2150860 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1932386 (MGI:6094959|PMID:28778798) RGD PMID:28778798 MGI:6094959 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (MGI:4355451|PMID:19667090) RGD PMID:19667090 MGI:4355451 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Glis2 GLIS family zinc finger 2 involved_in ISO (MGI:5292436|PMID:21816948) RGD PMID:21816948 MGI:5292436 NCBI chr10:11,154,459...11,177,063
Ensembl chr10:11,154,658...11,174,861
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:2159356|MGI:96533 (MGI:3790551|PMID:18477453), (MGI:4430672|PMID:19590577)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18477453 PMID:19590577 GO_REF:0000024 GO_REF:0000107 MGI:3790551 MGI:4430672 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5439169 (MGI:5512663|PMID:24062445)
Ensembl
RGD
PMID:24062445 GO_REF:0000107 MGI:5512663 NCBI chr13:51,985,698...51,992,547
Ensembl chr13:51,985,684...51,992,693
JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 involved_in ISO (PMID:31010679) RGD PMID:31010679 NCBI chr20:26,755,948...26,831,267
Ensembl chr20:26,755,911...26,830,931
JBrowse link
G Hhip Hedgehog-interacting protein involved_in
acts_upstream_of_or_within
ISO (MGI:5284801|PMID:15294024)
MGI:2450891 (MGI:1333378|PMID:10050855), (MGI:2450020|PMID:12569124)
RGD PMID:10050855 PMID:12569124 PMID:15294024 MGI:1333378 MGI:2450020 MGI:5284801 NCBI chr19:31,525,134...31,614,487
Ensembl chr19:31,524,671...31,614,246
JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within
involved_in
ISO MGI:3578529|MGI:95728 (MGI:6094959|PMID:28778798)
(MGI:4888042|PMID:21209331)
RGD PMID:21209331 PMID:28778798 MGI:4888042 MGI:6094959 NCBI chr 4:147,756,574...147,826,983
Ensembl chr 4:147,756,553...147,826,997
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO MGI:2682066 (MGI:6094959|PMID:28778798) RGD PMID:28778798 MGI:6094959 NCBI chr 6:26,390,686...26,485,459 JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 acts_upstream_of_or_within ISO (MGI:3603087|PMID:16148242) RGD PMID:16148242 MGI:3603087 NCBI chr10:56,489,552...56,491,715
Ensembl chr10:56,489,552...56,491,715
JBrowse link
G Kctd21 potassium channel tetramerization domain containing 21 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr 1:162,307,746...162,325,284
Ensembl chr 1:162,320,730...162,325,013
JBrowse link
G Kctd6 potassium channel tetramerization domain containing 6 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr15:18,484,607...18,493,188
Ensembl chr15:18,484,510...18,493,366
JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (MGI:4355635|PMID:19666503), (MGI:4357736|PMID:19549984), (MGI:4359116|PMID:19592253) RGD PMID:19549984 PMID:19592253 PMID:19666503 MGI:4355635 MGI:4357736 MGI:4359116 NCBI chr 1:141,434,183...141,452,592
Ensembl chr 1:141,434,625...141,451,075
JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:6111022|PMID:29290584)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:29290584 GO_REF:0000024 GO_REF:0000107 MGI:6111022 NCBI chr 1:82,184,671...82,234,045
Ensembl chr 1:82,185,034...82,234,045
JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6111022|PMID:29290584)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29290584 GO_REF:0000024 GO_REF:0000107 MGI:6111022 NCBI chr10:10,832,573...10,881,999
Ensembl chr10:10,833,519...10,881,977
JBrowse link
G Mosmo modulator of smoothened involved_in IBA
ISO
PMID:21873635
(MGI:6111022|PMID:29290584)
RGD PMID:29290584, PMID:21873635 MGI:6111022, RGD:13792537 NCBI chr 1:190,604,613...190,671,906
Ensembl chr 1:190,666,149...190,671,228
JBrowse link
G Ptch1 patched 1 involved_in ISO UniProtKB:Q62226 (MGI:5306540|PMID:21931618) RGD PMID:21931618 MGI:5306540 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:32467643) RGD PMID:32467643 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1931018|MGI:3574761 (MGI:3703460|PMID:17257418)
Ensembl
RGD
PMID:17257418 GO_REF:0000107 MGI:3703460 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176465 (MGI:3656469|PMID:15668330)
Ensembl
RGD
PMID:15668330 GO_REF:0000107 MGI:3656469 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:109295 (MGI:3829797|PMID:19168674) RGD PMID:19168674 MGI:3829797 NCBI chr19:23,387,737...23,405,025
Ensembl chr19:23,389,375...23,405,039
JBrowse link
G Sall3 spalt-like transcription factor 3 acts_upstream_of_or_within ISO MGI:1889585 (MGI:3829797|PMID:19168674) RGD PMID:19168674 MGI:3829797 NCBI chr18:77,572,200...77,591,710
Ensembl chr18:77,573,702...77,579,969
JBrowse link
G Serpine2 serpin family E member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98297 (MGI:3709698|PMID:17409116)
Ensembl
RGD
PMID:17409116 GO_REF:0000107 MGI:3709698 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within
ISO (PMID:27234298), (PMID:28965847)
(MGI:5789064|PMID:27234298)
(MGI:1346364|PMID:10531011)
MGI:3619046 (MGI:3616741|PMID:16459298), (MGI:3804352|PMID:18488998)
RGD PMID:10531011 PMID:16459298 PMID:18488998 PMID:27234298 PMID:28965847 MGI:1346364 MGI:3616741 MGI:3804352 MGI:5789064 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016
JBrowse link
G Tulp3 TUB like protein 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20889716)
MGI:2388066|MGI:3664273 (MGI:3841513|PMID:19223390), (MGI:3844764|PMID:19334287)
RGD PMID:19223390 PMID:19334287 PMID:20889716 MGI:3841513 MGI:3844764 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS
(PMID:20643644)
GO_REF:0000024
RGD
UniProt
PMID:20643644 GO_REF:0000024 NCBI chr 8:62,368,548...62,375,229
Ensembl chr 8:62,368,998...62,374,504
JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:23747190) RGD PMID:23747190 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (MGI:1855801|PMID:10781055) RGD PMID:10781055 MGI:1855801 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:108075|MGI:99833 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:1,935,900...1,942,867
Ensembl chr17:1,936,163...1,942,865
JBrowse link
G Gpr161 G protein-coupled receptor 161 involved_in ISO (MGI:5468365|PMID:23332756) RGD PMID:23332756 MGI:5468365 NCBI chr13:83,530,389...83,576,117
Ensembl chr13:83,531,018...83,571,505
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97760 (MGI:5308523|PMID:22007132)
Ensembl
RGD
PMID:22007132 GO_REF:0000107 MGI:5308523 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within ISO MGI:97592 (MGI:5308523|PMID:22007132) RGD PMID:22007132 MGI:5308523 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:266,143,766...266,241,742
Ensembl chr 1:266,143,818...266,239,016
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (MGI:5298450|PMID:21945076) RGD PMID:21945076 MGI:5298450 NCBI chr 9:98,621,499...98,658,223
Ensembl chr 9:98,621,506...98,656,901
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3844764|PMID:19334287) RGD PMID:19334287 MGI:3844764 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ift122 intraflagellar transport 122 involved_in ISO (MGI:4888042|PMID:21209331) RGD PMID:21209331 MGI:4888042 NCBI chr 4:147,756,574...147,826,983
Ensembl chr 4:147,756,553...147,826,997
JBrowse link
G Rfx4 regulatory factor X4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3799278 (MGI:5430880|PMID:19887680)
RGD PMID:19887680, PMID:21873635 MGI:5430880, RGD:13792537 NCBI chr 7:25,831,358...25,909,976
Ensembl chr 7:25,808,419...25,907,849
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3841503|PMID:19286674) RGD PMID:19286674 MGI:3841503 NCBI chr 4:161,636,084...161,677,807
Ensembl chr 4:161,637,892...161,658,519
JBrowse link
positive regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc9 armadillo repeat containing 9 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6152361|PMID:29459677)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:29459677 GO_REF:0000024 GO_REF:0000107 MGI:6152361 NCBI chr 9:93,172,718...93,299,119
Ensembl chr 9:93,172,673...93,296,750
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within ISO MGI:5007063 (MGI:5316547|PMID:22280990) RGD PMID:22280990 MGI:5316547 NCBI chr 1:127,010,587...127,071,570
Ensembl chr 1:127,010,588...127,071,570
JBrowse link
G Cibar1 CBY1 interacting BAR domain containing 1 involved_in ISO (MGI:6152361|PMID:29459677) RGD PMID:29459677 MGI:6152361 NCBI chr 5:25,732,457...25,750,953
Ensembl chr 5:25,732,644...25,750,826
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:108075 (MGI:3619284|PMID:16543460) RGD PMID:16543460 MGI:3619284 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Dcdc2 doublecortin domain containing 2 involved_in ISO (PMID:21698230) RGD PMID:21698230 NCBI chr17:41,838,201...42,031,265
Ensembl chr17:41,838,201...42,031,265
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (MGI:5617062|PMID:25644602) RGD PMID:25644602 MGI:5617062 NCBI chr15:120,213...230,312
Ensembl chr15:120,372...228,977
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4359237 (MGI:3804352|PMID:18488998)
Ensembl
RGD
PMID:18488998 GO_REF:0000107 MGI:3804352 NCBI chr 8:5,217,054...5,436,969
Ensembl chr 8:5,217,217...5,429,581
JBrowse link
G Evc EvC ciliary complex subunit 1 involved_in ISO (MGI:3720528|PMID:17660199) RGD PMID:17660199 MGI:3720528 NCBI chr14:78,213,601...78,253,266
Ensembl chr14:78,213,635...78,253,266
JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961 (MGI:3621094|PMID:16540513), (MGI:3629544|PMID:16778080) RGD PMID:16540513 PMID:16778080 MGI:3621094 MGI:3629544 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1347476 (MGI:5486225|PMID:23383217)
Ensembl
RGD
PMID:23383217 GO_REF:0000107 MGI:5486225 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO MGI:1347472 (MGI:5486225|PMID:23383217) RGD PMID:23383217 MGI:5486225 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO MGI:2388397|MGI:3711070 (MGI:3710452|PMID:17504940), (MGI:3713422|PMID:17525797) RGD PMID:17504940 PMID:17525797 MGI:3710452 MGI:3713422 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gas8 growth arrest specific 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:6148647|PMID:21659505)
UniProt
RGD
PMID:21659505 GO_REF:0000024 MGI:6148647 NCBI chr19:56,316,367...56,335,873
Ensembl chr19:56,316,268...56,335,870
JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:17035233) RGD PMID:17035233 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2159355 (MGI:4367926|PMID:19733558)
Ensembl
RGD
PMID:19733558 GO_REF:0000107 MGI:4367926 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO MGI:2682066 (MGI:3804352|PMID:18488998) RGD PMID:18488998 MGI:3804352 NCBI chr 6:26,390,686...26,485,459 JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (MGI:5142377|PMID:11517919) RGD PMID:11517919 MGI:5142377 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4441401 (MGI:5545722|PMID:22935613)
Ensembl
RGD
PMID:22935613 GO_REF:0000107 MGI:5545722 NCBI chr 2:127,459,089...127,521,327
Ensembl chr 2:127,459,012...127,525,437
JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (MGI:4355635|PMID:19666503), (MGI:4357736|PMID:19549984) RGD PMID:19549984 PMID:19666503 MGI:4355635 MGI:4357736 NCBI chr 1:141,434,183...141,452,592
Ensembl chr 1:141,434,625...141,451,075
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:98297 (MGI:3588476|PMID:16020517) RGD PMID:16020517 MGI:3588476 NCBI chr18:55,951,497...56,014,107
Ensembl chr18:55,955,389...55,992,885
JBrowse link
G Pdcl phosducin-like involved_in ISS
ISO
GO_REF:0000024
(MGI:6111022|PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 MGI:6111022 NCBI chr 3:21,602,349...21,609,821
Ensembl chr 3:21,601,816...21,609,853
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of_or_within ISO MGI:98218 (MGI:2149056|PMID:11532916) RGD PMID:11532916 MGI:2149056 NCBI chr13:81,147,038...81,215,559
Ensembl chr13:81,147,348...81,214,546
JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of_or_within ISO MGI:97712 (MGI:2149056|PMID:11532916) RGD PMID:11532916 MGI:2149056 NCBI chr 3:9,681,871...9,718,051
Ensembl chr 3:9,681,871...9,718,051
JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in ISS
ISO
GO_REF:0000024
(MGI:6111022|PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 MGI:6111022 NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 7:124,501,988...124,620,755
Ensembl chr 7:124,501,988...124,620,703
JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 1:174,428,056...174,495,356
Ensembl chr 1:174,428,699...174,495,258
JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr20:7,718,260...7,749,847
Ensembl chr20:7,718,282...7,746,331
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:17035233)
GO_REF:0000107
RGD
Ensembl
PMID:17035233 GO_REF:0000107 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5142377|PMID:11517919)
GO_REF:0000107
(PMID:19561609)
UniProt
RGD
Ensembl
PMID:11517919 PMID:19561609 GO_REF:0000024 GO_REF:0000107 MGI:5142377 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Shox2 short stature homeobox 2 acts_upstream_of_or_within ISO MGI:3605739 (MGI:3714677|PMID:17481601) RGD PMID:17481601 MGI:3714677 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (MGI:5300220|PMID:21937600) RGD PMID:21937600 MGI:5300220 NCBI chr18:73,145,596...73,199,395
Ensembl chr18:73,157,973...73,193,377
JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:3616743|PMID:16459297)
GO_REF:0000107
RGD
Ensembl
PMID:16459297, PMID:21873635 GO_REF:0000107 MGI:3616743, RGD:13792537 NCBI chr 4:57,019,941...57,041,779
Ensembl chr 4:57,019,941...57,042,770
JBrowse link
G Stk36 serine/threonine kinase 36 involved_in ISO (MGI:4943382|PMID:18600476) RGD PMID:18600476 MGI:4943382 NCBI chr 9:81,880,175...81,908,014
Ensembl chr 9:81,880,177...81,907,273
JBrowse link
G Tedc1 tubulin epsilon and delta complex 1 involved_in ISO (MGI:6152361|PMID:29459677) RGD PMID:29459677 MGI:6152361 NCBI chr 6:137,967,119...137,976,324
Ensembl chr 6:137,967,401...137,980,217
JBrowse link
G Tedc2 tubulin epsilon and delta complex 2 involved_in ISO (MGI:6152361|PMID:29459677) RGD PMID:29459677 MGI:6152361 NCBI chr10:13,586,852...13,591,938
Ensembl chr10:13,586,648...13,591,953
JBrowse link
G Ttc23 tetratricopeptide repeat domain 23 involved_in ISS
ISO
GO_REF:0000024
(MGI:6152361|PMID:29459677)
UniProt
RGD
PMID:29459677 GO_REF:0000024 MGI:6152361 NCBI chr 1:128,604,324...128,687,900
Ensembl chr 1:128,606,770...128,687,893
JBrowse link
G Tubd1 tubulin, delta 1 involved_in ISO (MGI:6111022|PMID:29290584) RGD PMID:29290584 MGI:6111022 NCBI chr10:73,865,828...73,886,976
Ensembl chr10:73,868,943...73,886,669
JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in ISS
ISO
GO_REF:0000024
(MGI:6152361|PMID:29459677)
UniProt
RGD
PMID:29459677 GO_REF:0000024 MGI:6152361 NCBI chr17:9,429,171...9,441,628
Ensembl chr17:9,429,175...9,441,526
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:28992318) RGD PMID:28992318 NCBI chr13:60,568,102...60,603,812
Ensembl chr13:60,545,635...60,603,811
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS
(PMID:19878745), (PMID:20643644)
GO_REF:0000024
RGD
UniProt
PMID:19878745 PMID:20643644 GO_REF:0000024 NCBI chr 8:62,368,548...62,375,229
Ensembl chr 8:62,368,998...62,374,504
JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350 (MGI:3701031|PMID:16818445) RGD PMID:16818445 MGI:3701031 NCBI chr10:45,659,045...45,686,103
Ensembl chr10:45,659,143...45,681,393
JBrowse link
positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gorab golgin, RAB6-interacting acts_upstream_of_or_within ISO (MGI:5766823|PMID:26967474) RGD PMID:26967474 MGI:5766823 NCBI chr13:81,682,207...81,698,827
Ensembl chr13:81,682,018...81,698,833
JBrowse link
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:1,935,900...1,942,867
Ensembl chr17:1,936,163...1,942,865
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2145349 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2145349 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036
JBrowse link
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4887578 (MGI:4868517|PMID:21045211)
Ensembl
RGD
PMID:21045211 GO_REF:0000107 MGI:4868517 NCBI chr10:75,149,814...75,160,481
Ensembl chr10:75,149,814...75,160,480
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    cellular process 18457
      signal transduction 6956
        regulation of signal transduction 2963
          regulation of smoothened signaling pathway 94
            negative regulation of smoothened signaling pathway + 38
            positive regulation of smoothened signaling pathway + 43
            regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 11
Path 2
Term Annotations click to browse term
  biological_process 19612
    biological regulation 13583
      regulation of biological process 12857
        regulation of cellular process 12354
          signal transduction 6956
            cell surface receptor signaling pathway 2761
              smoothened signaling pathway 158
                regulation of smoothened signaling pathway 94
                  negative regulation of smoothened signaling pathway + 38
                  positive regulation of smoothened signaling pathway + 43
                  regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 11
paths to the root