Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
cell surface receptor signaling pathway (GO:0007166)
Annotations: Rat: (2786) Mouse: (2890) Human: (3136) Chinchilla: (2140) Bonobo: (2418) Dog: (2558) Squirrel: (2368) Pig: (2670)
Parent Terms Term With Siblings Child Terms
signal transduction +     
apoptotic signaling pathway +   
bile acid signaling pathway +   
calmodulin dependent kinase signaling pathway +   
carbohydrate mediated signaling +   
cell surface receptor signaling pathway +   
The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
chloroplast-nucleus signaling pathway 
dopamine receptor signaling pathway +   
endoplasmic reticulum unfolded protein response +   
ER-nucleus signaling pathway +   
extracellular ATP signaling 
G protein-coupled receptor signaling pathway +   
granzyme-mediated programmed cell death signaling pathway +   
hormone-mediated signaling pathway +   
hydrogen peroxide mediated signaling pathway +  
hypoxia-inducible factor-1alpha signaling pathway +   
immune response-regulating signaling pathway +   
intracellular receptor signaling pathway +   
intracellular signal transduction +   
ligand-gated ion channel signaling pathway +   
lipoprotein particle mediated signaling +   
mitochondria-nucleus signaling pathway  
necroptotic signaling pathway  
negative regulation of signal transduction +   
neuronal signal transduction +   
opioid growth factor receptor signaling pathway 
phototransduction +   
positive regulation of signal transduction +   
postsynaptic signal transduction +   
presynaptic signal transduction +   
red or far-red light signaling pathway +   
regulation of blood pressure by chemoreceptor signaling pathway 
regulation of floral organ abscission by signal transduction +  
regulation of signal transduction +   
salicylic acid mediated signaling pathway +  
serotonin receptor signaling pathway +   
signal transduction in absence of ligand +   
signal transduction involved in cellular response to ammonium ion 
signal transduction involved in filamentous growth 
signal transduction involved in positive regulation of conjugation with cellular fusion +  
signal transduction involved in regulation of gene expression  
sphingolipid mediated signaling pathway +   

Synonyms
Exact Synonyms: cell surface receptor linked signal transduction ;   cell surface receptor linked signaling pathway ;   cell surface receptor linked signalling pathway
Definition Sources: GOC:bf, GOC:mah, GOC:pr, GOC:signaling

paths to the root