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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamate receptor signaling pathway
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Accession:GO:0007215 term browser browse the term
Definition:A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: glutamate signaling pathway;   glutamate signalling pathway


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glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:11059594
RGD:1624291
G Gna11 G protein subunit alpha 11 JBrowse link 7 11,033,400 11,047,284 RGD:1624291
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:1624291
RGD:13792537
RGD:1600115
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1624291
G Kcnb1 potassium voltage-gated channel subfamily B member 1 JBrowse link 3 163,850,785 163,935,610 RGD:10047372
G Ncstn nicastrin JBrowse link 13 90,451,046 90,467,256 RGD:1624291
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:1624291
RGD:1600115
G Sstr1 somatostatin receptor 1 JBrowse link 6 79,252,914 79,258,611 RGD:1624291
adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07002241.1 RGD:1600115
G AABR07061755.1 RGD:1600115
G AC119691.1 RGD:1600115
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1600115
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:1600115
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:1600115
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:1624291
RGD:1600115
G Grm6 glutamate metabotropic receptor 6 JBrowse link 10 36,345,503 36,363,416 RGD:69945
G Grm7 glutamate metabotropic receptor 7 JBrowse link 4 142,452,616 143,368,460 RGD:728749
RGD:1600115
RGD:1624291
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:6484727
RGD:1600115
RGD:1624291
G Vom2r-ps45 vomeronasal 2 receptor, pseudogene 45 JBrowse link 1 69,496,309 69,523,063 RGD:1600115
AMPA selective glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plp1 proteolipid protein 1 JBrowse link X 107,494,326 107,511,355 RGD:30296668
G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07002241.1 RGD:13792537
G AABR07061755.1 RGD:13792537
G AC119691.1 RGD:13792537
G Dagla diacylglycerol lipase, alpha JBrowse link 1 226,297,013 226,353,712 RGD:1624291
RGD:13792537
G Daglb diacylglycerol lipase, beta JBrowse link 12 13,113,073 13,157,748 RGD:13792537
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:625670
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1624291
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:1304458
RGD:13792537
RGD:1600115
RGD:1624291
G Grm2 glutamate metabotropic receptor 2 JBrowse link 8 115,344,999 115,358,628 RGD:13792537
G Grm3 glutamate metabotropic receptor 3 JBrowse link 4 21,316,761 21,567,561 RGD:13792537
G Grm4 glutamate metabotropic receptor 4 JBrowse link 20 6,745,682 6,791,521 RGD:13792537
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:8553991
RGD:13792537
RGD:1600115
RGD:1624291
RGD:12050103
G Grm6 glutamate metabotropic receptor 6 JBrowse link 10 36,345,503 36,363,416 RGD:1624291
RGD:13792537
RGD:1600115
G Grm7 glutamate metabotropic receptor 7 JBrowse link 4 142,452,616 143,368,460 RGD:13792537
G Grm8 glutamate metabotropic receptor 8 JBrowse link 4 54,474,344 55,409,526 RGD:13792537
G Homer1 homer scaffold protein 1 JBrowse link 2 22,909,550 23,012,303 RGD:633021
RGD:13792537
G Homer2 homer scaffold protein 2 JBrowse link 1 143,443,300 143,535,579 RGD:13792537
G Homer3 homer scaffold protein 3 JBrowse link 16 20,880,447 20,890,968 RGD:13792537
G Trpm1 transient receptor potential cation channel, subfamily M, member 1 JBrowse link 1 124,983,391 125,101,759 RGD:1600115
RGD:1624291
G Vom2r-ps45 vomeronasal 2 receptor, pseudogene 45 JBrowse link 1 69,496,309 69,523,063 RGD:13792537
ionotropic glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
RGD:1600115
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 JBrowse link 1 81,852,423 81,881,565 RGD:1624291
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:8554161
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:8554161
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin JBrowse link 1 197,986,384 197,999,726 RGD:1624291
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 JBrowse link 10 15,984,520 16,047,209 RGD:8553637
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:1358550
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 JBrowse link 10 42,441,723 42,760,200 RGD:1600115
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:1600115
RGD:1624291
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 JBrowse link X 127,561,843 127,829,763 RGD:1600115
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 JBrowse link 8 1,548,145 2,045,874 RGD:1600115
G Grid1 glutamate ionotropic receptor delta type subunit 1 JBrowse link 16 11,170,831 11,932,197 RGD:1600115
G Grid2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 4 94,068,112 95,476,864 RGD:1600115
G Grik1 glutamate ionotropic receptor kainate type subunit 1 JBrowse link 11 27,811,954 28,213,940 RGD:1642466
RGD:1600115
G Grik2 glutamate ionotropic receptor kainate type subunit 2 JBrowse link 20 53,791,428 54,517,691 RGD:1600115
G Grik3 glutamate ionotropic receptor kainate type subunit 3 JBrowse link 5 143,500,441 143,715,546 RGD:1600115
G Grik4 glutamate ionotropic receptor kainate type subunit 4 JBrowse link 8 46,804,134 47,237,546 RGD:1600115
G Grik5 glutamate ionotropic receptor kainate type subunit 5 JBrowse link 1 81,885,516 81,946,731 RGD:1600115
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:1642190
RGD:13792537
RGD:1624291
RGD:1600115
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:1642190
RGD:1600115
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:1642190
RGD:1600115
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C JBrowse link 10 103,798,290 103,816,923 RGD:1600115
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D JBrowse link 1 101,819,068 101,859,146 RGD:1600115
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A JBrowse link 5 64,928,620 65,073,012 RGD:1642190
RGD:13792537
RGD:1600115
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B JBrowse link 7 12,764,993 12,771,310 RGD:632842
RGD:13792537
RGD:1600115
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8655534
negative regulation of glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:13673766
negative regulation of NMDA glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:13463453
G Slc6a9 solute carrier family 6 member 9 JBrowse link 5 136,669,674 136,703,702 RGD:1624291
NMDA selective glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:12050125
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B JBrowse link 4 169,541,620 170,000,216 RGD:12050132
G Kalrn kalirin, RhoGEF kinase JBrowse link 11 69,484,293 70,025,682 RGD:12050112
G Tiam1 TIAM Rac1 associated GEF 1 JBrowse link 11 29,931,083 30,061,173 RGD:12050147
phospholipase C-activating G protein-coupled glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grm1 glutamate metabotropic receptor 1 JBrowse link 1 4,753,141 5,165,859 RGD:728711
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:625594
RGD:728711
positive regulation of AMPA receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1600115
RGD:1624291
G Arc activity-regulated cytoskeleton-associated protein JBrowse link 7 115,907,097 115,911,059 RGD:10047209
RGD:13792537
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 JBrowse link 7 119,228,112 119,353,332 RGD:13515081
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 JBrowse link 1 192,613,766 192,708,371 RGD:13515082
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:13515082
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 JBrowse link 1 64,330,106 64,350,338 RGD:13515082
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1624291
RGD:1600115
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:1624291
RGD:1600115
positive regulation of glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Necab2 N-terminal EF-hand calcium binding protein 2 JBrowse link 19 52,086,325 52,112,633 RGD:1624291
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:7349315
RGD:1624291
G Unc13a unc-13 homolog A JBrowse link 16 20,056,398 20,103,951 RGD:1624291
RGD:1600115
positive regulation of NMDA glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:14397550
G Ccr2 C-C motif chemokine receptor 2 RGD:14397550
G Cfl1 cofilin 1 JBrowse link 1 220,869,805 220,873,337 RGD:11570552
G Ephb2 Eph receptor B2 JBrowse link 5 155,024,478 155,143,539 RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:14397550
G Ifngr1 interferon gamma receptor 1 JBrowse link 1 15,062,380 15,080,815 RGD:14397550
G Ifngr2 interferon gamma receptor 2 JBrowse link 11 31,694,339 31,712,611 RGD:14397550
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:13463453
G Rgs9 regulator of G-protein signaling 9 JBrowse link 10 97,509,971 97,582,188 RGD:1599994
regulation of AMPA receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 JBrowse link 7 119,228,112 119,353,332 RGD:8553817
RGD:13792537
RGD:1624291
RGD:8554136
RGD:8554069
RGD:8554789
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 JBrowse link 1 192,613,766 192,708,371 RGD:8553817
RGD:13792537
RGD:8554069
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 JBrowse link 10 95,954,160 96,015,484 RGD:8553817
RGD:13792537
RGD:1624291
RGD:8554069
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 JBrowse link 10 96,122,240 96,166,606 RGD:8554789
RGD:13792537
RGD:8554069
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 JBrowse link 1 64,374,547 64,405,380 RGD:8554789
RGD:13792537
RGD:1600115
RGD:1624291
RGD:8554069
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 JBrowse link 1 64,330,106 64,350,338 RGD:8553817
RGD:13792537
RGD:1624291
RGD:8554069
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 JBrowse link 1 220,474,485 220,480,723 RGD:8554136
RGD:1624291
RGD:10400859
RGD:8553646
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 JBrowse link 13 99,663,150 99,770,625 RGD:8554136
RGD:1624291
G Gsg1l GSG1-like JBrowse link 1 197,271,704 197,482,776 RGD:8553757
RGD:13792537
RGD:12859070
G LOC103690160 SH3 and multiple ankyrin repeat domains protein 2-like JBrowse link 1 215,208,591 215,246,638 RGD:13792537
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Mink1 misshapen-like kinase 1 JBrowse link 10 57,185,310 57,238,531 RGD:8553980
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8553502
G Nlgn2 neuroligin 2 JBrowse link 10 56,431,586 56,444,847 RGD:1624291
RGD:1600115
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:1600115
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1600115
RGD:1624291
G Prrt1 proline-rich transmembrane protein 1 JBrowse link 20 4,392,605 4,396,271 RGD:1624291
G Shank1 SH3 and multiple ankyrin repeat domains 1 JBrowse link 1 100,297,137 100,344,377 RGD:1624291
RGD:13792537
RGD:1600115
G Shank2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 1 217,149,156 217,593,950 RGD:13792537
G Shank3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 7 130,474,278 130,534,679 RGD:13792537
G Shisa6 shisa family member 6 JBrowse link 10 52,744,069 53,037,853 RGD:13792537
G Shisa7 shisa family member 7 JBrowse link 1 72,545,413 72,564,513 RGD:13792537
RGD:1624291
G Shisa8 shisa family member 8 JBrowse link 7 123,440,163 123,445,613 RGD:13792537
G Shisa9 shisa family member 9 JBrowse link 10 2,777,675 3,072,842 RGD:1624291
regulation of glutamate receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Frrs1l ferric-chelate reductase 1-like JBrowse link 5 73,997,958 74,029,381 RGD:1624291
RGD:13792537
RGD:1600115
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:1624291
G Prnp prion protein JBrowse link 3 124,515,917 124,531,320 RGD:1624291
regulation of kainate selective glutamate receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Klhl24 kelch-like family member 24 JBrowse link 11 84,613,101 84,643,674 RGD:1600115
G Neto1 neuropilin and tolloid like 1 JBrowse link 18 83,471,342 83,585,043 RGD:1624291
G Neto2 neuropilin and tolloid like 2 JBrowse link 19 22,450,579 22,486,530 RGD:1600115
regulation of NMDA receptor activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 JBrowse link 1 220,474,485 220,480,723 RGD:10400859
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:8553912
RGD:1624291
G Crhbp corticotropin releasing hormone binding protein JBrowse link 2 25,141,471 25,153,334 RGD:1600115
RGD:1624291
G Dapk1 death associated protein kinase 1 JBrowse link 17 4,297,038 4,454,941 RGD:1624291
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:8554754
RGD:11085451
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:11085451
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 JBrowse link 7 130,430,588 130,440,838 RGD:1624291
G Mef2c myocyte enhancer factor 2C JBrowse link 2 11,658,534 11,822,788 RGD:1624291
RGD:1600115
G Nlgn1 neuroligin 1 JBrowse link 2 111,057,291 111,973,681 RGD:8553502
RGD:1624291
RGD:11554338
RGD:8554760
G Nlgn3 neuroligin 3 JBrowse link X 71,199,390 71,227,460 RGD:1624291
RGD:8553412
RGD:1600115
G Nrxn1 neurexin 1 JBrowse link 6 13,886,757 15,191,660 RGD:1624291
RGD:1600115
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:8656012
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6484258
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:8553497
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 JBrowse link 8 97,277,250 97,405,095 RGD:1624291
RGD:1600115
G Rasgrf2 RAS protein-specific guanine nucleotide-releasing factor 2 JBrowse link 2 21,460,041 21,698,937 RGD:1624291
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:1600115
RGD:1624291
G Rph3a rabphilin 3A JBrowse link 12 41,073,296 41,149,799 RGD:11085451

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      signal transduction 6968
        cell surface receptor signaling pathway 2772
          glutamate receptor signaling pathway 111
            G protein-coupled glutamate receptor signaling pathway + 20
            ionotropic glutamate receptor signaling pathway + 29
            negative regulation of glutamate receptor signaling pathway + 4
            positive regulation of glutamate receptor signaling pathway + 20
            regulation of glutamate receptor signaling pathway + 59
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            cell surface receptor signaling pathway 2772
              glutamate receptor signaling pathway 111
                G protein-coupled glutamate receptor signaling pathway + 20
                ionotropic glutamate receptor signaling pathway + 29
                negative regulation of glutamate receptor signaling pathway + 4
                positive regulation of glutamate receptor signaling pathway + 20
                regulation of glutamate receptor signaling pathway + 59
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.