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ONTOLOGY REPORT - ANNOTATIONS


Term:Norrin signaling pathway
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Accession:GO:0110135 term browser browse the term
Definition:The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.



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Norrin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd4 frizzled class receptor 4 involved_in ISO (PMID:15035989), (PMID:17955262)
(MGI:3621833|PMID:15035989)
RGD PMID:15035989 PMID:17955262 MGI:3621833 NCBI chr 1:143,280,065...143,288,799
Ensembl chr 1:143,280,065...143,285,724
JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO (PMID:15035989), (PMID:17955262)
(MGI:3621833|PMID:15035989)
RGD PMID:15035989 PMID:17955262 MGI:3621833 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in ISO (MGI:3621833|PMID:15035989) RGD PMID:15035989 MGI:3621833 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
G Ndp norrin cystine knot growth factor NDP involved_in ISO (PMID:15035989), (PMID:17955262)
(MGI:3621833|PMID:15035989)
RGD PMID:15035989 PMID:17955262 MGI:3621833 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19494
    signaling 7461
      cell-cell signaling 1735
        cell surface receptor signaling pathway involved in cell-cell signaling 563
          Norrin signaling pathway 4
Path 2
Term Annotations click to browse term
  biological_process 19494
    biological regulation 13507
      regulation of biological process 12763
        regulation of cellular process 12223
          signal transduction 6883
            cell surface receptor signaling pathway 2780
              cell surface receptor signaling pathway involved in cell-cell signaling 563
                Norrin signaling pathway 4
paths to the root