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ONTOLOGY REPORT - ANNOTATIONS

Term:Norrin signaling pathway
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Accession:GO:0110135 term browser browse the term
Definition:The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.


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Norrin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fzd4 frizzled class receptor 4 involved_in ISO
IEA 		(PMID:15035989), (PMID:17955262)
GO_REF:0000107 		RGD
Ensembl		 PMID:15035989 PMID:17955262 GO_REF:0000107 NCBI chr 1:143,279,934...143,288,799
Ensembl chr 1:143,280,065...143,285,724 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO
IEA 		(PMID:15035989), (PMID:17955262)
GO_REF:0000107 		RGD
Ensembl		 PMID:15035989 PMID:17955262 GO_REF:0000107 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in ISO (PMID:15035989) RGD PMID:15035989 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Ndp norrin cystine knot growth factor NDP involved_in ISO
IBA
IEA 		(PMID:15035989), (PMID:17955262)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:15035989 PMID:17955262 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Tspan12 tetraspanin 12 acts_upstream_of_or_within ISO
IEA 		MGI:6105927 (PMID:30478038)
GO_REF:0000107 		RGD
Ensembl		 PMID:30478038 GO_REF:0000107 NCBI chr 4:50,313,768...50,389,246
Ensembl chr 4:50,313,772...50,389,246 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          Norrin signaling pathway 5
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        signaling 7874
          signal transduction 7313
            cell surface receptor signaling pathway 2915
              Norrin signaling pathway 5
paths to the root