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ONTOLOGY REPORT - ANNOTATIONS

Term:netrin-activated signaling pathway
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Accession:GO:0038007 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a netrin protein to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.
Synonyms:exact_synonym: netrin signaling pathway;   netrin-activated signal transduction pathway;   netrin-activated signalling pathway;   netrin-mediated signaling pathway


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netrin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dcc DCC netrin 1 receptor involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr18:67,144,272...68,248,159
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Dscam DS cell adhesion molecule involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
UniProtKB:O08747 (PMID:22685302) 		UniProt
Ensembl
RGD		 PMID:22685302 GO_REF:0000024 GO_REF:0000107 NCBI chr11:35,921,924...36,507,100
Ensembl chr11:35,926,896...36,507,415 		JBrowse link
G Shtn1 shootin 1 involved_in IDA PMID:23453953 UniProt PMID:23453953 RGD:10054078 NCBI chr 1:258,121,966...258,225,861
Ensembl chr 1:258,121,968...258,228,265 		JBrowse link
G Tubb3 tubulin, beta 3 class III involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28483977)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28483977 GO_REF:0000024 GO_REF:0000107 NCBI chr19:68,365,687...68,374,741
Ensembl chr19:51,457,184...51,466,243 		JBrowse link
G Unc5a unc-5 netrin receptor A involved_in IMP
IEA 		PMID:19755150
GO_REF:0000002 		InterPro PMID:19755150 GO_REF:0000002, RGD:10400861 NCBI chr17:9,614,841...9,670,558
Ensembl chr17:9,614,838...9,670,526 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Unc5c unc-5 netrin receptor C involved_in IEA
ISO 		GO_REF:0000002
GO_REF:0000107
UniProtKB:Q9ERC8 (PMID:22685302) 		InterPro
Ensembl
RGD		 PMID:22685302 GO_REF:0000002 GO_REF:0000107 NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217 		JBrowse link
G Unc5cl unc-5 family C-terminal like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:12,528,109...12,543,382
Ensembl chr 9:12,528,246...12,542,233 		JBrowse link
G Unc5d unc-5 netrin receptor D involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:62,860,119...63,406,932
Ensembl chr16:62,860,174...63,401,143 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          netrin-activated signaling pathway 9
            negative regulation of netrin-activated signaling pathway 0
            positive regulation of netrin-activated signaling pathway 0
            regulation of netrin-activated signaling pathway + 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        signaling 7874
          signal transduction 7313
            cell surface receptor signaling pathway 2915
              netrin-activated signaling pathway 9
                negative regulation of netrin-activated signaling pathway 0
                positive regulation of netrin-activated signaling pathway 0
                regulation of netrin-activated signaling pathway + 0
paths to the root