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ONTOLOGY REPORT - ANNOTATIONS


Term:smoothened signaling pathway
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Accession:GO:0007224 term browser browse the term
Definition:The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
Synonyms:exact_synonym: hedgehog signaling pathway;   smoothened signalling pathway
 narrow_synonym: Sonic hedgehog signaling pathway;   hh signaling pathway;   hh signalling pathway
 related_synonym: Shh signaling pathway
 xref: Wikipedia:Hedgehog_signaling_pathway



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smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Arl13b ADP-ribosylation factor like GTPase 13B involved_in ISO (MGI:3707691|PMID:17488627), (MGI:5553238|PMID:21976698) RGD PMID:17488627 PMID:21976698 MGI:3707691 MGI:5553238 NCBI chr11:150,100...217,103
Ensembl chr11:150,955...217,197
JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5317033|PMID:21289087)
GO_REF:0000107
RGD
Ensembl
PMID:21289087 GO_REF:0000107 MGI:5317033 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820
JBrowse link
G B9d1 B9 domain containing 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5300833|PMID:22179047)
UniProt
RGD
PMID:22179047 GO_REF:0000024 MGI:5300833 NCBI chr10:46,186,222...46,196,309
Ensembl chr10:46,186,691...46,196,008
JBrowse link
G Bbs7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within ISO MGI:98715 (MGI:5314314|PMID:22228099) RGD PMID:22228099 MGI:5314314 NCBI chr 2:119,434,760...119,474,665
Ensembl chr 2:119,434,760...119,474,396
JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated acts_upstream_of_or_within ISO (MGI:3624617|PMID:16647303) RGD PMID:16647303 MGI:3624617 NCBI chr11:56,122,697...56,198,060
Ensembl chr11:56,122,750...56,198,059
JBrowse link
G Cc2d2a coiled-coil and C2 domain containing 2A acts_upstream_of_or_within ISO MGI:5708063 (MGI:5300833|PMID:22179047), (MGI:5696765|PMID:24947469) RGD PMID:22179047 PMID:24947469 MGI:5300833 MGI:5696765 NCBI chr14:67,349,004...67,435,883
Ensembl chr14:67,351,353...67,435,949
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of ISO (MGI:1888832|PMID:10981962) RGD PMID:10981962 MGI:1888832 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cdon cell adhesion associated, oncogene regulated involved_in
acts_upstream_of_or_within
IEA
IDA
ISO
GO_REF:0000107
PMID:16647303
MGI:98297 (MGI:3624618|PMID:16647304)
Ensembl
RGD
PMID:16647304 PMID:16647303 GO_REF:0000107 MGI:3624618, RGD:8554425 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033
JBrowse link
G Cenpj centromere protein J acts_upstream_of_or_within ISO MGI:2448985|MGI:4432238 (MGI:5563859|PMID:24706806) RGD PMID:24706806 MGI:5563859 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791
JBrowse link
G Cfap410 cilia and flagella associated protein 410 acts_upstream_of_or_within ISO (MGI:5317033|PMID:21289087) RGD PMID:21289087 MGI:5317033 NCBI chr20:10,687,863...10,694,736
Ensembl chr20:10,687,863...10,694,737
JBrowse link
G Chrd chordin involved_in ISO MGI:104327|MGI:1313268 (MGI:2389288|PMID:12397106) RGD PMID:12397106 MGI:2389288 NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673
JBrowse link
G Cluap1 clusterin associated protein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:105373|MGI:4363468 (MGI:5488668|PMID:23351563), (MGI:5509110|PMID:23742838)
GO_REF:0000107
RGD
Ensembl
PMID:23351563 PMID:23742838 GO_REF:0000107 MGI:5488668 MGI:5509110 NCBI chr10:11,587,963...11,619,711
Ensembl chr10:11,588,017...11,619,711
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887372|MGI:6887373 (MGI:6107986|PMID:29038301) RGD PMID:29038301 MGI:6107986 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of ISO MGI:108075 (MGI:3619284|PMID:16543460) RGD PMID:16543460 MGI:3619284 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Dhh desert hedgehog signaling molecule involved_in
acts_upstream_of_or_within
TAS
IBA
ISO
GO_REF:0000033
(MGI:5698232|PMID:25639508)
GO_Central
RGD
PMID:25639508 PMID:11118005 GO_REF:0000033 MGI:5698232, RGD:634737 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Disp1 dispatched RND transporter family member 1 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:105373|MGI:98297 (MGI:3051703|PMID:15269168)
GO_REF:0000033
RGD
GO_Central
PMID:15269168 GO_REF:0000033 MGI:3051703 NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702
JBrowse link
G Disp2 dispatched RND transporter family member 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:105,762,303...105,777,826
Ensembl chr 3:105,762,305...105,777,800
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in ISO (PMID:18455992) RGD PMID:18455992 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106
JBrowse link
G Dzip1 DAZ interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:5557987 (MGI:5554981|PMID:23955340) RGD PMID:23955340 MGI:5554981 NCBI chr15:95,956,329...96,009,994
Ensembl chr15:95,956,398...96,010,066
JBrowse link
G Dzip1l DAZ interacting zinc finger protein 1-like acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:6357158 (MGI:6149643|PMID:29487109)
GO_REF:0000107
RGD
Ensembl
PMID:29487109 GO_REF:0000107 MGI:6149643 NCBI chr 8:100,188,414...100,229,077
Ensembl chr 8:100,194,999...100,228,988
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO MGI:3785162 (MGI:6504350|PMID:32980560) RGD PMID:32980560 MGI:6504350 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Evc EvC ciliary complex subunit 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099
JBrowse link
G Evc2 EvC ciliary complex subunit 2 involved_in ISO (MGI:5294521|PMID:21356043) RGD PMID:21356043 MGI:5294521 NCBI chr14:73,366,832...73,454,539
Ensembl chr14:73,367,963...73,454,516
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:5609888|PMID:25053416), (MGI:6160687|PMID:29700203), (MGI:6199721|PMID:29545125) RGD PMID:25053416 PMID:29545125 PMID:29700203 MGI:5609888 MGI:6160687 MGI:6199721 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of ISO MGI:2135961 (MGI:3621094|PMID:16540513), (MGI:3629544|PMID:16778080) RGD PMID:16540513 PMID:16778080 MGI:3621094 MGI:3629544 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 acts_upstream_of_or_within ISO MGI:3042750|MGI:98297 (MGI:3039989|PMID:15105374) RGD PMID:15105374 MGI:3039989 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
JBrowse link
G Foxa1 forkhead box A1 acts_upstream_of
involved_in
ISO
IEA
MGI:1347476 (MGI:5486225|PMID:23383217)
GO_REF:0000107
RGD
Ensembl
PMID:23383217 GO_REF:0000107 MGI:5486225 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of ISO MGI:1347472 (MGI:5486225|PMID:23383217) RGD PMID:23383217 MGI:5486225 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO (MGI:2135612|PMID:11493558) RGD PMID:11493558 MGI:2135612 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of ISO MGI:2388397|MGI:3711070 (MGI:3710452|PMID:17504940), (MGI:3713422|PMID:17525797) RGD PMID:17504940 PMID:17525797 MGI:3710452 MGI:3713422 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli1 GLI family zinc finger 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:19878745), (PMID:31279575)
GO_REF:0000033
MGI:95728 (MGI:1306711|PMID:9769173), (MGI:3624180|PMID:16571625), (MGI:3790581|PMID:18449196), (MGI:3836883|PMID:19124651), (MGI:5465379|PMID:23201751)
RGD
GO_Central
PMID:9769173 PMID:16571625 PMID:18449196 PMID:19124651 PMID:19878745 More... GO_REF:0000033 MGI:1306711 MGI:3624180 MGI:3790581 MGI:3836883 MGI:5465379 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gli2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:15994174), (PMID:31279575)
GO_REF:0000033
MGI:1857509|MGI:2446434|MGI:3664541|MGI:3834146|MGI:95727 (MGI:3624180|PMID:16571625), (MGI:3833793|PMID:19056373), (MGI:3836883|PMID:19124651)
RGD
GO_Central
PMID:15994174 PMID:16571625 PMID:19056373 PMID:19124651 PMID:31279575 GO_REF:0000033 MGI:3624180 MGI:3833793 MGI:3836883 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within
TAS
IBA
ISO
GO_REF:0000033
MGI:106676 (MGI:5314312|PMID:22234993)
MGI:108075|MGI:96533|MGI:98297 (MGI:2445271|PMID:12435628), (MGI:3608261|PMID:16284117), (MGI:3611729|PMID:16396903), (MGI:3624182|PMID:16571630), (MGI:3686547|PMID:17043310)
(PMID:31279575)
GO_Central
RGD
PMID:12435628 PMID:16284117 PMID:16396903 PMID:16571630 PMID:17043310 More... GO_REF:0000033 MGI:2445271 MGI:3608261 MGI:3611729 MGI:3624182 MGI:3686547 MGI:5314312, RGD:1303367 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Gpc2 glypican 2 involved_in IMP
IBA
GO_REF:0000033 GO_Central
RGD
PMID:20231458 GO_REF:0000033, RGD:5510027 NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208
JBrowse link
G Gpc3 glypican 3 acts_upstream_of
involved_in
ISO
IEA
MGI:2159355 (MGI:4367926|PMID:19733558)
GO_REF:0000107
RGD
Ensembl
PMID:19733558 GO_REF:0000107 MGI:4367926 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of ISO MGI:5439169 (MGI:5512663|PMID:24062445) RGD PMID:24062445 MGI:5512663 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3836883|PMID:19124651)
Ensembl
RGD
PMID:19124651 GO_REF:0000107 MGI:3836883 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes5 hes family bHLH transcription factor 5 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3836883|PMID:19124651)
UniProt
RGD
PMID:19124651 GO_REF:0000024 MGI:3836883 NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
JBrowse link
G Hhat hedgehog acyltransferase acts_upstream_of_or_within ISO MGI:3051900|MGI:3051901 (MGI:3039193|PMID:15075292) RGD PMID:15075292 MGI:3039193 NCBI chr13:104,024,507...104,283,580
Ensembl chr13:104,010,916...104,282,893
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
MGI:1314872 (MGI:3619785|PMID:16537918)
Ensembl
GO_Central
TreeGrafter
RGD
PMID:16537918 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:3619785 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:1314872 (MGI:3619785|PMID:16537918) RGD PMID:16537918 MGI:3619785 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IDA RGD PMID:21720682 RGD:5510033 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
JBrowse link
G Ift172 intraflagellar transport 172 involved_in ISO
IEA
(MGI:1926671|PMID:11062270)
GO_REF:0000107
RGD
Ensembl
PMID:11062270 GO_REF:0000107 MGI:1926671 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Ift20 intraflagellar transport 20 acts_upstream_of_or_within ISO (MGI:4361064|PMID:19654211) RGD PMID:19654211 MGI:4361064 NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124
JBrowse link
G Ift25 intraflagellar transport 25 involved_in ISO (MGI:5426280|PMID:22595669) RGD PMID:22595669 MGI:5426280 NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421
JBrowse link
G Ift27 intraflagellar transport 27 involved_in ISO (MGI:5605390|PMID:25446516) RGD PMID:25446516 MGI:5605390 NCBI chr 7:109,738,622...109,754,416
Ensembl chr 7:109,738,622...109,754,416
JBrowse link
G Ift46 intraflagellar transport 46 acts_upstream_of_or_within ISO (MGI:5317033|PMID:21289087) RGD PMID:21289087 MGI:5317033 NCBI chr 8:45,081,593...45,104,052
Ensembl chr 8:45,087,440...45,104,052
JBrowse link
G Ift52 intraflagellar transport 52 acts_upstream_of_or_within ISO (MGI:3579954|PMID:15930098) RGD PMID:15930098 MGI:3579954 NCBI chr 3:151,672,505...151,696,975
Ensembl chr 3:151,672,493...151,696,980
JBrowse link
G Ift56 intraflagellar transport 56 involved_in ISS
ISO
GO_REF:0000024
(MGI:5608603|PMID:25340710), (MGI:5887147|PMID:28264835)
UniProt
RGD
PMID:25340710 PMID:28264835 GO_REF:0000024 MGI:5608603 MGI:5887147 NCBI chr 4:67,090,622...67,154,707
Ensembl chr 4:67,090,660...67,147,903
JBrowse link
G Ift57 intraflagellar transport 57 acts_upstream_of_or_within ISO MGI:3707373 (MGI:3703110|PMID:17027958) RGD PMID:17027958 MGI:3703110 NCBI chr11:51,051,520...51,124,909
Ensembl chr11:51,059,611...51,124,812
JBrowse link
G Ift80 intraflagellar transport 80 acts_upstream_of_or_within ISO MGI:3665440|MGI:3689350|MGI:3856827|MGI:5818514 (MGI:4940140|PMID:21227999), (MGI:5473722|PMID:23333501), (MGI:5807019|PMID:26996322), (MGI:5817320|PMID:26098911), (MGI:6458221|PMID:30683845) RGD PMID:21227999 PMID:23333501 PMID:26098911 PMID:26996322 PMID:30683845 MGI:4940140 MGI:5473722 MGI:5807019 MGI:5817320 MGI:6458221 NCBI chr 2:153,144,707...153,240,024
Ensembl chr 2:153,145,795...153,240,024
JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:2157527|MGI:2445832|MGI:3027342|MGI:3710185|MGI:3823090|MGI:98297 (MGI:3579954|PMID:15930098), (MGI:3821634|PMID:19036983), (MGI:4361064|PMID:19654211), (MGI:4949010|PMID:21429982), (MGI:5314314|PMID:22228099) RGD PMID:15930098 PMID:19036983 PMID:19654211 PMID:21429982 PMID:22228099 MGI:3579954 MGI:3821634 MGI:4361064 MGI:4949010 MGI:5314314 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21537345)
(MGI:5142377|PMID:11517919)
GO_REF:0000033
MGI:104903 (MGI:4430672|PMID:19590577), (MGI:5698232|PMID:25639508)
RGD
GO_Central
PMID:11517919 PMID:19590577 PMID:21537345 PMID:25639508 GO_REF:0000033 MGI:4430672 MGI:5142377 MGI:5698232 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Intu inturned planar cell polarity protein acts_upstream_of
involved_in
ISO
IEA
MGI:4441401 (MGI:5545722|PMID:22935613)
GO_REF:0000107
RGD
Ensembl
PMID:22935613 GO_REF:0000107 MGI:5545722 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676
JBrowse link
G Iqub IQ motif and ubiquitin domain containing acts_upstream_of_or_within ISO (MGI:5317033|PMID:21289087) RGD PMID:21289087 MGI:5317033 NCBI chr 4:52,931,768...52,993,795
Ensembl chr 4:52,931,767...52,993,834
JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 acts_upstream_of ISO (MGI:3603087|PMID:16148242) RGD PMID:16148242 MGI:3603087 NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760
JBrowse link
G Kiaa0586 KIAA0586 homolog involved_in ISO
IBA
(MGI:5286003|PMID:21750036)
GO_REF:0000033
RGD
GO_Central
PMID:21750036 GO_REF:0000033 MGI:5286003 NCBI chr 6:89,622,711...89,725,951
Ensembl chr 6:89,623,699...89,725,962
JBrowse link
G Kif3a kinesin family member 3a acts_upstream_of_or_within
involved_in
ISO MGI:1861960|MGI:2179048|MGI:2386464 (MGI:3794243|PMID:18297065), (MGI:3841503|PMID:19286674)
(MGI:5896703|PMID:27793670)
RGD PMID:18297065 PMID:19286674 PMID:27793670 MGI:3794243 MGI:3841503 MGI:5896703 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191
JBrowse link
G Map3k10 mitogen activated protein kinase kinase kinase 10 involved_in ISO (PMID:18455992) RGD PMID:18455992 NCBI chr 1:82,955,784...82,974,084
Ensembl chr 1:82,955,207...82,974,084
JBrowse link
G Mosmo modulator of smoothened acts_upstream_of_or_within ISO (MGI:6781668|PMID:34486668) RGD PMID:34486668 MGI:6781668 NCBI chr 1:175,217,680...175,288,521
Ensembl chr 1:175,217,545...175,288,334
JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (MGI:5465379|PMID:23201751) RGD PMID:23201751 MGI:5465379 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934
JBrowse link
G Nkx2-2 NK2 homeobox 2 acts_upstream_of_or_within ISO (MGI:3806189|PMID:18590716) RGD PMID:18590716 MGI:3806189 NCBI chr 3:134,619,701...134,630,282
Ensembl chr 3:134,620,039...134,622,411
JBrowse link
G Nkx6-1 NK6 homeobox 1 acts_upstream_of_or_within ISO (MGI:3806189|PMID:18590716) RGD PMID:18590716 MGI:3806189 NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681
JBrowse link
G Nog noggin involved_in ISO
IEA
MGI:104327|MGI:1313268 (MGI:2389288|PMID:12397106)
GO_REF:0000107
RGD
Ensembl
PMID:12397106 GO_REF:0000107 MGI:2389288 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like acts_upstream_of_or_within ISO MGI:105373 (MGI:3690259|PMID:17028112) RGD PMID:17028112 MGI:3690259 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3806189|PMID:18590716)
Ensembl
RGD
PMID:18590716 GO_REF:0000107 MGI:3806189 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 IMP RGD PMID:11181516 RGD:2311195 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (MGI:5559921|PMID:24336288) RGD PMID:24336288 MGI:5559921 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031
JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of ISO MGI:98218 (MGI:2149056|PMID:11532916) RGD PMID:11532916 MGI:2149056 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866
JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of ISO MGI:97712 (MGI:2149056|PMID:11532916) RGD PMID:11532916 MGI:2149056 NCBI chr 3:14,132,574...14,168,533
Ensembl chr 3:14,094,004...14,168,535
JBrowse link
G Ptch1 patched 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptchd1 patched domain containing 1 involved_in ISO (PMID:20844286) RGD PMID:20844286 NCBI chr  X:39,681,910...39,733,416
Ensembl chr  X:39,681,910...39,733,519
JBrowse link
G Ptpdc1 protein tyrosine phosphatase domain containing 1 acts_upstream_of_or_within ISO (MGI:5317033|PMID:21289087) RGD PMID:21289087 MGI:5317033 NCBI chr17:16,028,964...16,076,512
Ensembl chr17:16,049,382...16,076,512
JBrowse link
G Rb1 RB transcriptional corepressor 1 acts_upstream_of
involved_in
ISO
IEA
MGI:1931018|MGI:3574761 (MGI:3703460|PMID:17257418)
GO_REF:0000107
RGD
Ensembl
PMID:17257418 GO_REF:0000107 MGI:3703460 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Ro60 Ro60, Y RNA binding protein acts_upstream_of_or_within ISO (MGI:5317033|PMID:21289087) RGD PMID:21289087 MGI:5317033 NCBI chr13:55,499,514...55,520,504
Ensembl chr13:55,499,534...55,520,504
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 acts_upstream_of_or_within ISO MGI:3793279 (MGI:4822496|PMID:20660756) RGD PMID:20660756 MGI:4822496 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
JBrowse link
G Runx2 RUNX family transcription factor 2 acts_upstream_of
involved_in
ISO
IEA
MGI:2176465 (MGI:3656469|PMID:15668330)
GO_REF:0000107
RGD
Ensembl
PMID:15668330 GO_REF:0000107 MGI:3656469 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of ISO MGI:109295 (MGI:3829797|PMID:19168674) RGD PMID:19168674 MGI:3829797 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
G Sall3 spalt-like transcription factor 3 acts_upstream_of ISO MGI:1889585 (MGI:3829797|PMID:19168674) RGD PMID:19168674 MGI:3829797 NCBI chr18:74,406,066...74,425,974
Ensembl chr18:74,407,560...74,426,789
JBrowse link
G Septin2 septin 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:4462072|PMID:20558667)
UniProt
RGD
PMID:20558667 GO_REF:0000024 MGI:4462072 NCBI chr 9:94,018,141...94,051,386
Ensembl chr 9:94,018,208...94,051,386
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within
ISO
IBA
ISS
(PMID:17850284), (PMID:31279575)
(MGI:5142377|PMID:11517919)
GO_REF:0000033
MGI:108075|MGI:1857796|MGI:1916147|MGI:95728 (MGI:1336531|PMID:10340755), (MGI:1338342|PMID:10375501), (MGI:1928592|PMID:11118883), (MGI:3051703|PMID:15269168), (MGI:3624046|PMID:16611981), (MGI:3653954|PMID:16880529), (MGI:3686547|PMID:17043310), (MGI:5698232|PMID:25639508), (MGI:84001|PMID:8906787)
(MGI:3039193|PMID:15075292)
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:8906787 PMID:10340755 PMID:10375501 PMID:11118883 PMID:11517919 More... GO_REF:0000024 GO_REF:0000033 MGI:1336531 MGI:1338342 MGI:1928592 MGI:3039193 MGI:3051703 MGI:3624046 MGI:3653954 MGI:3686547 MGI:5142377 MGI:5698232 MGI:84001 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Shox2 SHOX homeobox 2 acts_upstream_of
involved_in
ISO
IEA
MGI:3605739 (MGI:3714677|PMID:17481601)
GO_REF:0000107
RGD
Ensembl
PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of ISO MGI:5300464 (MGI:5300220|PMID:21937600) RGD PMID:21937600 MGI:5300220 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342
JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
ISS
IBA
ISO
IEA
GO_REF:0000024
GO_REF:0000033
MGI:1934268|MGI:2176173|MGI:2176255|MGI:2176256|MGI:2445832|MGI:2684317|MGI:95729|MGI:98297 (MGI:3040160|PMID:15107405), (MGI:3606828|PMID:16136078), (MGI:3624180|PMID:16571625), (MGI:3686547|PMID:17043310), (MGI:3696007|PMID:17199044), (MGI:3841503|PMID:19286674), (MGI:4833770|PMID:20185815), (MGI:6149643|PMID:29487109), (MGI:7262356|PMID:35353806)
(MGI:4888042|PMID:21209331), (MGI:5142377|PMID:11517919), (MGI:5285138|PMID:21177415), (MGI:5896703|PMID:27793670), (MGI:6868252|PMID:23831757)
GO_REF:0000107
(PMID:17850284), (PMID:19304771), (PMID:21177415), (PMID:32413283), (PMID:36202993), (PMID:9422511)
UniProt
GO_Central
RGD
Ensembl
PMID:9422511 PMID:11517919 PMID:15107405 PMID:16136078 PMID:16571625 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:3040160 MGI:3606828 MGI:3624180 MGI:3686547 MGI:3696007 MGI:3841503 MGI:4833770 MGI:4888042 MGI:5142377 MGI:5285138 MGI:5896703 MGI:6149643 MGI:6868252 MGI:7262356 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Stil STIL, centriolar assembly protein acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2152962 (MGI:1339521|PMID:10385121)
GO_REF:0000033
RGD
GO_Central
PMID:10385121 GO_REF:0000033 MGI:1339521 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730
JBrowse link
G Stk36 serine/threonine kinase 36 involved_in ISO
IBA
(PMID:31279575)
(MGI:4943382|PMID:18600476)
GO_REF:0000033
RGD
GO_Central
PMID:18600476 PMID:31279575 GO_REF:0000033 MGI:4943382 NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_negative_effect ISO MGI:4461193 (MGI:6149643|PMID:29487109)
MGI:3619046 (MGI:3616741|PMID:16459298)
RGD PMID:16459298 PMID:29487109 MGI:3616741 MGI:6149643 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:4127851|MGI:4440463 (MGI:4439200|PMID:20159594) RGD PMID:20159594 MGI:4439200 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415
JBrowse link
G Tctn2 tectonic family member 2 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:5013991|PMID:21565611)
UniProt
GO_Central
TreeGrafter
RGD
PMID:21565611 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5013991 NCBI chr12:31,982,440...32,007,242
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Tctn3 tectonic family member 3 involved_in ISO (PMID:22883145) RGD PMID:22883145 NCBI chr 1:239,414,003...239,425,273
Ensembl chr 1:239,415,203...239,425,272
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2384513 (MGI:3829327|PMID:18990706)
GO_REF:0000107
RGD
Ensembl
PMID:18990706 GO_REF:0000107 MGI:3829327 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Tmem17 transmembrane protein 17 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:5300833|PMID:22179047)
UniProt
RGD
PMID:22179047 GO_REF:0000024 MGI:5300833 NCBI chr14:96,483,648...96,524,238
Ensembl chr14:96,518,793...96,524,233
JBrowse link
G Tmem231 transmembrane protein 231 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5300833|PMID:22179047)
UniProt
Ensembl
RGD
PMID:22179047 GO_REF:0000024 GO_REF:0000107 MGI:5300833 NCBI chr19:39,883,077...39,904,296
Ensembl chr19:39,883,077...39,904,269
JBrowse link
G Ttbk2 tau tubulin kinase 2 involved_in ISO (MGI:5493390|PMID:23141541) RGD PMID:23141541 MGI:5493390 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544|MGI:2179048|MGI:5587034 (MGI:3784018|PMID:18327258), (MGI:6152587|PMID:29615573) RGD PMID:18327258 PMID:29615573 MGI:3784018 MGI:6152587 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903
JBrowse link
G Tuba1a tubulin, alpha 1A involved_in ISO (MGI:5896703|PMID:27793670) RGD PMID:27793670 MGI:5896703 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of ISO MGI:3664273 (MGI:3841513|PMID:19223390) RGD PMID:19223390 MGI:3841513 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO (PMID:31279575) RGD PMID:31279575 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
JBrowse link
G Wdpcp WD repeat containing planar cell polarity effector acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:5558098 (MGI:5544506|PMID:24302887)
GO_REF:0000107
RGD
Ensembl
PMID:24302887 GO_REF:0000107 MGI:5544506 NCBI chr14:95,645,955...95,977,120
Ensembl chr14:95,646,038...95,977,113
JBrowse link
G Wdr19 WD repeat domain 19 acts_upstream_of_or_within ISO MGI:5315747|MGI:5315748 (MGI:5314316|PMID:22228095) RGD PMID:22228095 MGI:5314316 NCBI chr14:43,042,474...43,106,337
Ensembl chr14:43,042,478...43,106,288
JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (MGI:3703195|PMID:17284610) RGD PMID:17284610 MGI:3703195 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of ISO MGI:3701350 (MGI:3701031|PMID:16818445) RGD PMID:16818445 MGI:3701031 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133
JBrowse link
G Zfp423 zinc finger protein 423 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5805574|PMID:27727273)
GO_REF:0000107
RGD
Ensembl
PMID:27727273 GO_REF:0000107 MGI:5805574 NCBI chr19:19,111,213...19,407,373
Ensembl chr19:19,110,238...19,407,373
JBrowse link
G Zic3 Zic family member 3 involved_in ISO MGI:95729 (MGI:5314312|PMID:22234993) RGD PMID:22234993 MGI:5314312 NCBI chr  X:136,123,662...136,129,627
Ensembl chr  X:136,124,026...136,134,746
JBrowse link
mesenchymal smoothened signaling pathway involved in prostate gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:2386799|PMID:12221011)
GO_REF:0000107
RGD
Ensembl
PMID:12221011 GO_REF:0000107 MGI:2386799 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
negative regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (MGI:1888832|PMID:10981962) RGD PMID:10981962 MGI:1888832 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:108075|MGI:99833 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO MGI:1931521 (MGI:1307032|PMID:9811582) RGD PMID:9811582 MGI:1307032 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (MGI:2150860|PMID:11572986) RGD PMID:11572986 MGI:2150860 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1932386 (MGI:6094959|PMID:28778798) RGD PMID:28778798 MGI:6094959 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (MGI:4355451|PMID:19667090) RGD PMID:19667090 MGI:4355451 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Glis2 GLIS family zinc finger 2 involved_in ISO (MGI:5292436|PMID:21816948) RGD PMID:21816948 MGI:5292436 NCBI chr10:10,951,157...10,978,524
Ensembl chr10:10,951,371...10,971,578
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:2159356|MGI:96533 (MGI:3790551|PMID:18477453), (MGI:4430672|PMID:19590577)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18477453 PMID:19590577 GO_REF:0000024 GO_REF:0000107 MGI:3790551 MGI:4430672 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Gpr37l1 G protein-coupled receptor 37-like 1 acts_upstream_of_or_within ISO MGI:5439169 (MGI:5512663|PMID:24062445) RGD PMID:24062445 MGI:5512663 NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 involved_in ISO (PMID:31010679) RGD PMID:31010679 NCBI chr20:25,329,972...25,404,657
Ensembl chr20:25,330,280...25,404,657
JBrowse link
G Hhip Hedgehog-interacting protein involved_in
acts_upstream_of_or_within
ISO (MGI:5284801|PMID:15294024)
MGI:2450891 (MGI:1333378|PMID:10050855), (MGI:2450020|PMID:12569124)
RGD PMID:10050855 PMID:12569124 PMID:15294024 MGI:1333378 MGI:2450020 MGI:5284801 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within
involved_in
ISO MGI:3578529|MGI:95728 (MGI:6094959|PMID:28778798)
(MGI:4888042|PMID:21209331)
RGD PMID:21209331 PMID:28778798 MGI:4888042 MGI:6094959 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2682066 (MGI:6094959|PMID:28778798)
GO_REF:0000107
RGD
Ensembl
PMID:28778798 GO_REF:0000107 MGI:6094959 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Kctd11 potassium channel tetramerization domain containing 11 acts_upstream_of_or_within ISO (MGI:3603087|PMID:16148242) RGD PMID:16148242 MGI:3603087 NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760
JBrowse link
G Kctd21 potassium channel tetramerization domain containing 21 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr 1:151,650,074...151,669,775
Ensembl chr 1:151,650,104...151,667,645
JBrowse link
G Kctd6 potassium channel tetramerization domain containing 6 involved_in ISO (PMID:21472142) RGD PMID:21472142 NCBI chr15:16,695,297...16,712,460
Ensembl chr15:16,695,297...16,698,699
JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (MGI:4355635|PMID:19666503), (MGI:4357736|PMID:19549984), (MGI:4359116|PMID:19592253) RGD PMID:19549984 PMID:19592253 PMID:19666503 MGI:4355635 MGI:4357736 MGI:4359116 NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576
JBrowse link
G Megf8 multiple EGF-like-domains 8 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:6111022|PMID:29290584)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:29290584 GO_REF:0000024 GO_REF:0000107 MGI:6111022 NCBI chr 1:80,902,236...80,951,614
Ensembl chr 1:80,902,574...80,951,613
JBrowse link
G Mgrn1 mahogunin ring finger 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6111022|PMID:29290584)
UniProt
Ensembl
RGD
PMID:29290584 GO_REF:0000024 GO_REF:0000107 MGI:6111022 NCBI chr10:10,638,881...10,688,332
Ensembl chr10:10,638,880...10,688,315
JBrowse link
G Mir29a microRNA 29a IDA RGD PMID:32544883 RGD:243065126 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir9 microRNA 9 IDA RGD PMID:32544883 RGD:243065126 NCBI chr 9:1,080,274...1,080,383
Ensembl chr 9:1,080,274...1,080,383
JBrowse link
G Mosmo modulator of smoothened involved_in ISO (MGI:6111022|PMID:29290584) RGD PMID:29290584 MGI:6111022 NCBI chr 1:175,217,680...175,288,521
Ensembl chr 1:175,217,545...175,288,334
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:97760 (MGI:5308523|PMID:22007132)
GO_REF:0000107
RGD
Ensembl
PMID:22007132 GO_REF:0000107 MGI:5308523 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:97592 (MGI:5308523|PMID:22007132)
GO_REF:0000107
RGD
Ensembl
PMID:22007132 GO_REF:0000107 MGI:5308523 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Ptch1 patched 1 involved_in
acts_upstream_of_or_within
ISO
IBA
UniProtKB:Q62226 (MGI:5306540|PMID:21931618)
GO_REF:0000033
MGI:1857447|MGI:1916147|MGI:2142166|MGI:2153143 (MGI:2135612|PMID:11493558), (MGI:2152606|PMID:11784021), (MGI:3051703|PMID:15269168), (MGI:3821640|PMID:19004860), (MGI:4355593|PMID:19684112), (MGI:4367286|PMID:19809516), (MGI:85754|PMID:9006067)
RGD
GO_Central
PMID:9006067 PMID:11493558 PMID:11784021 PMID:15269168 PMID:19004860 More... GO_REF:0000033 MGI:2135612 MGI:2152606 MGI:3051703 MGI:3821640 MGI:4355593 MGI:4367286 MGI:5306540 MGI:85754 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Ptch2 patched 2 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405
JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:32467643) RGD PMID:32467643 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1931018|MGI:3574761 (MGI:3703460|PMID:17257418)
Ensembl
RGD
PMID:17257418 GO_REF:0000107 MGI:3703460 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rfx4 regulatory factor X4 acts_upstream_of_or_within ISO MGI:3799278 (MGI:5430880|PMID:19887680) RGD PMID:19887680 MGI:5430880 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176465 (MGI:3656469|PMID:15668330)
Ensembl
RGD
PMID:15668330 GO_REF:0000107 MGI:3656469 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Sall1 spalt-like transcription factor 1 acts_upstream_of_or_within ISO MGI:109295 (MGI:3829797|PMID:19168674) RGD PMID:19168674 MGI:3829797 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705
JBrowse link
G Sall3 spalt-like transcription factor 3 acts_upstream_of_or_within ISO MGI:1889585 (MGI:3829797|PMID:19168674) RGD PMID:19168674 MGI:3829797 NCBI chr18:74,406,066...74,425,974
Ensembl chr18:74,407,560...74,426,789
JBrowse link
G Serpine2 serpin family E member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98297 (MGI:3709698|PMID:17409116)
Ensembl
RGD
PMID:17409116 GO_REF:0000107 MGI:3709698 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within
ISO (PMID:27234298), (PMID:28965847)
MGI:3619046|MGI:4840420 (MGI:3616741|PMID:16459298), (MGI:3804352|PMID:18488998), (MGI:4355593|PMID:19684112)
(MGI:5789064|PMID:27234298)
(MGI:1346364|PMID:10531011)
RGD PMID:10531011 PMID:16459298 PMID:18488998 PMID:19684112 PMID:27234298 More... MGI:1346364 MGI:3616741 MGI:3804352 MGI:4355593 MGI:5789064 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:7262356|PMID:35353806)
GO_REF:0000107
RGD
Ensembl
PMID:35353806 GO_REF:0000107 MGI:7262356 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Traf3ip1 TRAF3 interacting protein 1 acts_upstream_of_or_within ISO MGI:4129326 (MGI:5298450|PMID:21945076) RGD PMID:21945076 MGI:5298450 NCBI chr 9:92,073,622...92,110,427
Ensembl chr 9:92,073,640...92,108,977
JBrowse link
G Tulp3 TUB like protein 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20889716)
MGI:2388066|MGI:3664273 (MGI:3841503|PMID:19286674), (MGI:3841513|PMID:19223390), (MGI:3844764|PMID:19334287)
RGD PMID:19223390 PMID:19286674 PMID:19334287 PMID:20889716 MGI:3841503 MGI:3841513 MGI:3844764 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS
(PMID:20643644)
GO_REF:0000024
RGD
UniProt
PMID:20643644 GO_REF:0000024 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
JBrowse link
G Vcp valosin-containing protein involved_in ISO (PMID:23747190) RGD PMID:23747190 NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (MGI:1855801|PMID:10781055) RGD PMID:10781055 MGI:1855801 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581
JBrowse link
negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr161 G protein-coupled receptor 161 involved_in ISO (MGI:5468365|PMID:23332756) RGD PMID:23332756 MGI:5468365 NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613
JBrowse link
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rfx4 regulatory factor X4 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:18,853,065...19,015,378
Ensembl chr 7:18,853,322...19,014,967
JBrowse link
positive regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07063281.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Armc9 armadillo repeat containing 9 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6152361|PMID:29459677)
UniProt
Ensembl
RGD
PMID:29459677 GO_REF:0000024 GO_REF:0000107 MGI:6152361 NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:86,802,868...86,928,860
JBrowse link
G Chsy1 chondroitin sulfate synthase 1 acts_upstream_of_or_within ISO MGI:5007063 (MGI:5316547|PMID:22280990) RGD PMID:22280990 MGI:5316547 NCBI chr 1:119,689,626...119,750,711
Ensembl chr 1:119,686,350...119,750,601
JBrowse link
G Cibar1 CBY1 interacting BAR domain containing 1 involved_in ISO (MGI:6152361|PMID:29459677) RGD PMID:29459677 MGI:6152361 NCBI chr 5:25,613,993...25,632,440
Ensembl chr 5:25,614,033...25,632,489
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:108075 (MGI:3619284|PMID:16543460) RGD PMID:16543460 MGI:3619284 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Dcdc2 doublecortin domain containing 2 involved_in ISO (PMID:21698230) RGD PMID:21698230 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743
JBrowse link
G Dhh desert hedgehog signaling molecule involved_in ISO (PMID:24342078)
(PMID:33063110)
RGD PMID:24342078 PMID:33063110 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (MGI:5617062|PMID:25644602) RGD PMID:25644602 MGI:5617062 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:4359237 (MGI:3804352|PMID:18488998)
GO_REF:0000107
RGD
Ensembl
PMID:18488998 GO_REF:0000107 MGI:3804352 NCBI chr 8:4,189,067...4,412,183
Ensembl chr 8:4,189,257...4,412,183
JBrowse link
G Evc EvC ciliary complex subunit 1 involved_in ISO (MGI:3720528|PMID:17660199) RGD PMID:17660199 MGI:3720528 NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099
JBrowse link
G Fgf9 fibroblast growth factor 9 acts_upstream_of_or_within ISO MGI:2135961 (MGI:3621094|PMID:16540513), (MGI:3629544|PMID:16778080) RGD PMID:16540513 PMID:16778080 MGI:3621094 MGI:3629544 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
JBrowse link
G Foxa1 forkhead box A1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1347476 (MGI:5486225|PMID:23383217)
Ensembl
RGD
PMID:23383217 GO_REF:0000107 MGI:5486225 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 acts_upstream_of_or_within ISO MGI:1347472 (MGI:5486225|PMID:23383217) RGD PMID:23383217 MGI:5486225 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO MGI:2388397|MGI:3711070 (MGI:3710452|PMID:17504940), (MGI:3713422|PMID:17525797) RGD PMID:17504940 PMID:17525797 MGI:3710452 MGI:3713422 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gas8 growth arrest specific 8 involved_in ISS
ISO
GO_REF:0000024
(MGI:6148647|PMID:21659505)
UniProt
RGD
PMID:21659505 GO_REF:0000024 MGI:6148647 NCBI chr19:51,552,770...51,572,323
Ensembl chr19:51,552,816...51,572,305
JBrowse link
G Gli1 GLI family zinc finger 1 involved_in ISO (PMID:17035233) RGD PMID:17035233 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251
JBrowse link
G Gorab golgin, RAB6-interacting acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5766823|PMID:26967474)
GO_REF:0000107
RGD
Ensembl
PMID:26967474 GO_REF:0000107 MGI:5766823 NCBI chr13:75,745,678...75,762,307
Ensembl chr13:75,745,680...75,762,298
JBrowse link
G Gpc3 glypican 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2159355 (MGI:4367926|PMID:19733558)
Ensembl
RGD
PMID:19733558 GO_REF:0000107 MGI:4367926 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2682066 (MGI:3804352|PMID:18488998)
GO_REF:0000107
RGD
Ensembl
PMID:18488998 GO_REF:0000107 MGI:3804352 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO (PMID:24342078) RGD PMID:24342078 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4441401 (MGI:5545722|PMID:22935613)
Ensembl
RGD
PMID:22935613 GO_REF:0000107 MGI:5545722 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676
JBrowse link
G Isl1 ISL LIM homeobox 1 IDA RGD PMID:32544883 RGD:243065126 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
JBrowse link
G Kif7 kinesin family member 7 involved_in ISO (MGI:4355635|PMID:19666503), (MGI:4357736|PMID:19549984) RGD PMID:19549984 PMID:19666503 MGI:4355635 MGI:4357736 NCBI chr 1:133,639,487...133,658,539
Ensembl chr 1:133,640,065...133,658,576
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 acts_upstream_of_or_within ISO MGI:98297 (MGI:3588476|PMID:16020517) RGD PMID:16020517 MGI:3588476 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Pdcl phosducin like involved_in ISS
ISO
GO_REF:0000024
(MGI:6111022|PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 MGI:6111022 NCBI chr 3:21,110,165...21,119,763
Ensembl chr 3:21,110,167...21,119,715
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Prrx1 paired related homeobox 1 acts_upstream_of_or_within ISO MGI:98218 (MGI:2149056|PMID:11532916) RGD PMID:11532916 MGI:2149056 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866
JBrowse link
G Prrx2 paired related homeobox 2 acts_upstream_of_or_within ISO MGI:97712 (MGI:2149056|PMID:11532916) RGD PMID:11532916 MGI:2149056 NCBI chr 3:14,132,574...14,168,533
Ensembl chr 3:14,094,004...14,168,535
JBrowse link
G Rab34 RAB34, member RAS oncogene family involved_in ISS
ISO
GO_REF:0000024
(MGI:6111022|PMID:29290584)
UniProt
RGD
PMID:29290584 GO_REF:0000024 MGI:6111022 NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940
JBrowse link
G Scube2 signal peptide, CUB domain and EGF like domain containing 2 acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr 1:163,831,876...163,899,925
Ensembl chr 1:163,832,015...163,899,393
JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 acts_upstream_of_or_within ISO (MGI:5698232|PMID:25639508) RGD PMID:25639508 MGI:5698232 NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA
(PMID:17035233)
GO_REF:0000107
RGD
Ensembl
PMID:17035233 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:19561609), (PMID:24342078)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19561609 PMID:24342078 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Shox2 SHOX homeobox 2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3605739 (MGI:3714677|PMID:17481601)
GO_REF:0000107
RGD
Ensembl
PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (MGI:5300220|PMID:21937600) RGD PMID:21937600 MGI:5300220 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342
JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3616743|PMID:16459297)
Ensembl
RGD
PMID:16459297 GO_REF:0000107 MGI:3616743 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829
JBrowse link
G Stk36 serine/threonine kinase 36 involved_in ISO (MGI:4943382|PMID:18600476) RGD PMID:18600476 MGI:4943382 NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422
JBrowse link
G Tedc1 tubulin epsilon and delta complex 1 involved_in ISO (MGI:6152361|PMID:29459677) RGD PMID:29459677 MGI:6152361 NCBI chr 6:132,234,764...132,245,164
Ensembl chr 6:132,236,925...132,244,928
JBrowse link
G Tedc2 tubulin epsilon and delta complex 2 involved_in ISO (MGI:6152361|PMID:29459677) RGD PMID:29459677 MGI:6152361 NCBI chr10:13,246,032...13,251,196
Ensembl chr10:13,246,037...13,251,124
JBrowse link
G Ttc23 tetratricopeptide repeat domain 23 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:6152361|PMID:29459677)
UniProt
Ensembl
RGD
PMID:29459677 GO_REF:0000024 GO_REF:0000107 MGI:6152361 NCBI chr 1:121,245,996...121,329,500
Ensembl chr 1:121,248,084...121,329,494
JBrowse link
G Tubd1 tubulin, delta 1 involved_in ISO (MGI:6111022|PMID:29290584) RGD PMID:29290584 MGI:6111022 NCBI chr10:71,367,936...71,391,387
Ensembl chr10:71,368,133...71,391,266
JBrowse link
G Txndc15 thioredoxin domain containing 15 involved_in ISS
ISO
GO_REF:0000024
(MGI:6152361|PMID:29459677)
UniProt
RGD
PMID:29459677 GO_REF:0000024 MGI:6152361 NCBI chr17:8,898,074...8,910,538
Ensembl chr17:8,845,084...8,910,539
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:28992318) RGD PMID:28992318 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
JBrowse link
G Ulk3 unc-51 like kinase 3 involved_in ISO
ISS
(PMID:19878745), (PMID:20643644)
GO_REF:0000024
RGD
UniProt
PMID:19878745 PMID:20643644 GO_REF:0000024 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350 (MGI:3701031|PMID:16818445) RGD PMID:16818445 MGI:3701031 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133
JBrowse link
regulation of smoothened signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actrt1 actin-related protein T1 involved_in ISO
ISS
(PMID:28869610)
GO_REF:0000024
RGD
UniProt
PMID:28869610 GO_REF:0000024 NCBI chr  X:125,584,102...125,585,455
Ensembl chr  X:125,584,065...125,585,457
JBrowse link
G Arl6 ADP-ribosylation factor like GTPase 6 acts_upstream_of_or_within ISO MGI:5310744 (MGI:5306530|PMID:22139371) RGD PMID:22139371 MGI:5306530 NCBI chr11:40,711,878...40,738,254
Ensembl chr11:40,712,022...40,737,937
JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within ISO MGI:105373|MGI:99833 (MGI:3821640|PMID:19004860) RGD PMID:19004860 MGI:3821640 NCBI chr 1:154,715,151...154,812,955
Ensembl chr 1:154,715,310...154,812,520
JBrowse link
G Cdk20 cyclin-dependent kinase 20 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
JBrowse link
G Cplane2 ciliogenesis and planar polarity effector complex subunit 2 acts_upstream_of_or_within ISO MGI:6887372|MGI:6887373 (MGI:6107986|PMID:29038301) RGD PMID:29038301 MGI:6107986 NCBI chr 5:153,515,507...153,516,455
Ensembl chr 5:153,515,376...153,522,508
JBrowse link
G Efcab7 EF-hand calcium binding domain 7 involved_in ISO (MGI:5908325|PMID:24582806) RGD PMID:24582806 MGI:5908325 NCBI chr 5:114,525,403...114,576,130
Ensembl chr 5:114,525,167...114,576,129
JBrowse link
G Fbxl17 F-box and leucine-rich repeat protein 17 involved_in ISO (PMID:27234298) RGD PMID:27234298 NCBI chr 9:102,780,573...103,206,978
Ensembl chr 9:102,782,440...103,208,950
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647|MGI:1927833 (MGI:3588480|PMID:15958512), (MGI:3722952|PMID:16618415) RGD PMID:15958512 PMID:16618415 MGI:3588480 MGI:3722952 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (MGI:3722952|PMID:16618415) RGD PMID:16618415 MGI:3722952 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fuz fuzzy planar cell polarity protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4438317|PMID:19767740), (MGI:5009776|PMID:20962855), (MGI:5296432|PMID:21935430), (MGI:5498583|PMID:23806618)
MGI:4346364 (MGI:4367921|PMID:19877275)
UniProt
RGD
PMID:19767740 PMID:19877275 PMID:20962855 PMID:21935430 PMID:23806618 GO_REF:0000024 MGI:4367921 MGI:4438317 MGI:5009776 MGI:5296432 MGI:5498583 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Gas1 growth arrest-specific 1 involved_in ISO (MGI:4357747|PMID:19478089) RGD PMID:19478089 MGI:4357747 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2145349 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2145349 (MGI:5912686|PMID:28817564) RGD PMID:28817564 MGI:5912686 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Ift140 intraflagellar transport 140 acts_upstream_of_or_within ISO MGI:4458412 (MGI:5635784|PMID:24009529) RGD PMID:24009529 MGI:5635784 NCBI chr10:14,032,665...14,121,682
Ensembl chr10:14,032,648...14,120,433
JBrowse link
G Ift172 intraflagellar transport 172 acts_upstream_of_or_within ISO MGI:4821824 (MGI:5285455|PMID:21653639) RGD PMID:21653639 MGI:5285455 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860
JBrowse link
G Ift81 intraflagellar transport 81 involved_in ISS
ISO
GO_REF:0000024
(PMID:27666822)
UniProt
RGD
PMID:27666822 GO_REF:0000024 NCBI chr12:33,957,744...34,037,164
Ensembl chr12:33,957,806...34,037,057
JBrowse link
G Intu inturned planar cell polarity protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:4441234|PMID:20067783)
(MGI:5644615|PMID:25774014)
UniProt
RGD
PMID:20067783 PMID:25774014 GO_REF:0000024 MGI:4441234 MGI:5644615 NCBI chr 2:123,600,972...123,685,331
Ensembl chr 2:123,609,807...123,682,676
JBrowse link
G Iqce IQ motif containing E involved_in ISO (MGI:5908325|PMID:24582806) RGD PMID:24582806 MGI:5908325 NCBI chr12:13,943,290...13,982,708
Ensembl chr12:13,943,487...13,982,693
JBrowse link
G Mks1 MKS transition zone complex subunit 1 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:4433029|MGI:4887578 (MGI:4868517|PMID:21045211), (MGI:5487695|PMID:23454480)
GO_REF:0000107
RGD
Ensembl
PMID:21045211 PMID:23454480 GO_REF:0000107 MGI:4868517 MGI:5487695 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655
JBrowse link
G Ptch1 patched 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333
JBrowse link
G Rab23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO MGI:2142166 (MGI:3821640|PMID:19004860) RGD PMID:19004860 MGI:3821640 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927
JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO (MGI:2683830|PMID:14687547) RGD PMID:14687547 MGI:2683830 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rpgrip1l Rpgrip1-like acts_upstream_of_or_within ISO MGI:3716208 (MGI:3715393|PMID:17553904) RGD PMID:17553904 MGI:3715393 NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083
JBrowse link
G Tctn1 tectonic family member 1 acts_upstream_of_or_within ISO MGI:3716885 (MGI:3610767|PMID:16357211) RGD PMID:16357211 MGI:3610767 NCBI chr12:34,309,795...34,347,190
Ensembl chr12:34,309,897...34,342,267
JBrowse link
G Ttbk2 tau tubulin kinase 2 acts_upstream_of_or_within ISO MGI:5496675 (MGI:5493390|PMID:23141541) RGD PMID:23141541 MGI:5493390 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2152544 (MGI:4367927|PMID:19732765) RGD PMID:19732765 MGI:4367927 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:2388066 (MGI:3841503|PMID:19286674) RGD PMID:19286674 MGI:3841503 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Wdr11 WD repeat domain 11 involved_in ISO (MGI:6116377|PMID:29263200) RGD PMID:29263200 MGI:6116377 NCBI chr 1:184,165,260...184,210,834
Ensembl chr 1:184,165,571...184,210,846
JBrowse link
G Zic1 Zic family member 1 involved_in ISO UniProtKB:P47806 (MGI:3688043|PMID:11238441) RGD PMID:11238441 MGI:3688043 NCBI chr 8:91,908,548...91,918,020
Ensembl chr 8:91,908,576...91,912,731
JBrowse link
smoothened signaling pathway involved in dorsal/ventral neural tube patterning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:2442827|MGI:95729 (MGI:3709667|PMID:17395647), (MGI:4439200|PMID:20159594) RGD PMID:17395647 PMID:20159594 MGI:3709667 MGI:4439200 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:2442827|MGI:95728 (MGI:3709667|PMID:17395647), (MGI:4439200|PMID:20159594) RGD PMID:17395647 PMID:20159594 MGI:3709667 MGI:4439200 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Ift122 intraflagellar transport 122 acts_upstream_of_or_within ISO MGI:2443231 (MGI:5428054|PMID:22689656) RGD PMID:22689656 MGI:5428054 NCBI chr 4:148,905,031...148,975,458
Ensembl chr 4:148,905,046...148,975,458
JBrowse link
G Tbc1d32 TBC1 domain family, member 32 acts_upstream_of_or_within ISO MGI:95728|MGI:95729 (MGI:4439200|PMID:20159594) RGD PMID:20159594 MGI:4439200 NCBI chr20:35,359,865...35,590,992
Ensembl chr20:35,359,863...35,590,415
JBrowse link
G Tulp3 TUB like protein 3 acts_upstream_of_or_within ISO MGI:3664273 (MGI:3841513|PMID:19223390) RGD PMID:19223390 MGI:3841513 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Wdr19 WD repeat domain 19 acts_upstream_of_or_within ISO MGI:1932386|MGI:5315748 (MGI:5428054|PMID:22689656) RGD PMID:22689656 MGI:5428054 NCBI chr14:43,042,474...43,106,337
Ensembl chr14:43,042,478...43,106,288
JBrowse link
smoothened signaling pathway involved in lung development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:5912649|PMID:28859094) RGD PMID:28859094 MGI:5912649 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mks1 MKS transition zone complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4821832 (MGI:5811184|PMID:27340223)
Ensembl
RGD
PMID:27340223 GO_REF:0000107 MGI:5811184 NCBI chr10:72,655,921...72,667,007
Ensembl chr10:72,655,921...72,666,655
JBrowse link
smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
smoothened signaling pathway involved in ventral spinal cord interneuron specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95729 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (MGI:3051712|PMID:15215207) RGD PMID:15215207 MGI:3051712 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within ISO MGI:4840420 (MGI:4355593|PMID:19684112) RGD PMID:19684112 MGI:4355593 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20295
    cellular process 18772
      signal transduction 7171
        cell surface receptor signaling pathway 2883
          smoothened signaling pathway 170
            ciliary receptor clustering involved in smoothened signaling pathway 0
            mesenchymal smoothened signaling pathway involved in prostate gland development 1
            negative regulation of smoothened signaling pathway + 42
            positive regulation of smoothened signaling pathway + 46
            regulation of smoothened signaling pathway + 103
            smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 7
            smoothened signaling pathway involved in lung development 1
            smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 0
            smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
            smoothened signaling pathway involved in ventral spinal cord patterning + 4
Path 2
Term Annotations click to browse term
  biological_process 20295
    biological regulation 13636
      regulation of biological process 13225
        signaling 7735
          signal transduction 7171
            cell surface receptor signaling pathway 2883
              smoothened signaling pathway 170
                ciliary receptor clustering involved in smoothened signaling pathway 0
                mesenchymal smoothened signaling pathway involved in prostate gland development 1
                negative regulation of smoothened signaling pathway + 42
                positive regulation of smoothened signaling pathway + 46
                regulation of smoothened signaling pathway + 103
                smoothened signaling pathway involved in dorsal/ventral neural tube patterning + 7
                smoothened signaling pathway involved in lung development 1
                smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation 0
                smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1
                smoothened signaling pathway involved in ventral spinal cord patterning + 4
paths to the root