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ONTOLOGY REPORT - ANNOTATIONS


Term:cell surface receptor signaling pathway
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Accession:GO:0007166 term browser browse the term
Definition:A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: cell surface receptor linked signal transduction;   cell surface receptor linked signaling pathway;   cell surface receptor linked signalling pathway
 xref: MIPS_funcat:30.05


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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    signaling 7456
      signal transduction 6872
        cell surface receptor signaling pathway 2674
          CD40 signaling pathway + 13
          Fas signaling pathway + 4
          Notch signaling pathway + 175
          Roundabout signaling pathway + 6
          Toll signaling pathway + 7
          anti-Mullerian hormone signaling pathway + 1
          apolipoprotein A-I-mediated signaling pathway + 5
          cell surface bile acid receptor signaling pathway 1
          cell surface receptor signaling pathway involved in cell-cell signaling + 553
          cell surface receptor signaling pathway involved in heart development + 27
          collagen-activated signaling pathway + 16
          cytokine-mediated signaling pathway + 386
          enzyme linked receptor protein signaling pathway + 925
          extrinsic apoptotic signaling pathway + 233
          glutamate receptor signaling pathway + 106
          immune response-regulating cell surface receptor signaling pathway + 309
          integrin-mediated signaling pathway + 109
          lipopolysaccharide-mediated signaling pathway + 56
          netrin-activated signaling pathway + 9
          neuropilin signaling pathway + 4
          neurotrophin signaling pathway + 42
          positive regulation of integrin activation by cell surface receptor linked signal transduction 2
          purinergic nucleotide receptor signaling pathway + 32
          receptor signaling pathway via STAT + 182
          reelin-mediated signaling pathway 7
          semaphorin-plexin signaling pathway + 45
          smoothened signaling pathway + 155
          urokinase plasminogen activator signaling pathway 2
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        regulation of cellular process 11995
          signal transduction 6872
            cell surface receptor signaling pathway 2674
              CD40 signaling pathway + 13
              Fas signaling pathway + 4
              Notch signaling pathway + 175
              Roundabout signaling pathway + 6
              Toll signaling pathway + 7
              anti-Mullerian hormone signaling pathway + 1
              apolipoprotein A-I-mediated signaling pathway + 5
              cell surface bile acid receptor signaling pathway 1
              cell surface receptor signaling pathway involved in cell-cell signaling + 553
              cell surface receptor signaling pathway involved in heart development + 27
              collagen-activated signaling pathway + 16
              cytokine-mediated signaling pathway + 386
              enzyme linked receptor protein signaling pathway + 925
              extrinsic apoptotic signaling pathway + 233
              glutamate receptor signaling pathway + 106
              immune response-regulating cell surface receptor signaling pathway + 309
              integrin-mediated signaling pathway + 109
              lipopolysaccharide-mediated signaling pathway + 56
              netrin-activated signaling pathway + 9
              neuropilin signaling pathway + 4
              neurotrophin signaling pathway + 42
              positive regulation of integrin activation by cell surface receptor linked signal transduction 2
              purinergic nucleotide receptor signaling pathway + 32
              receptor signaling pathway via STAT + 182
              reelin-mediated signaling pathway 7
              semaphorin-plexin signaling pathway + 45
              smoothened signaling pathway + 155
              urokinase plasminogen activator signaling pathway 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.