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ONTOLOGY REPORT - ANNOTATIONS


Term:apoptotic signaling pathway
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Accession:GO:0097190 term browser browse the term
Definition:The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Comment:This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
Synonyms:exact_synonym: apoptotic signalling pathway;   induction of apoptosis by extracellular signals
 alt_id: GO:0008624



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apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07054614.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Adora2a adenosine A2a receptor acts_upstream_of ISO MGI:2155985 (PMID:10845921) RGD PMID:10845921 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Anxa6 annexin A6 involved_in ISO
IBA
IEA
(MGI:5485084|PMID:23341998)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
RGD
GO_Central
TreeGrafter
Ensembl
PMID:23341998 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:5485084 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:2675966|MGI:3029528 (PMID:11717309), (PMID:12931191), (PMID:15231831) RGD PMID:11717309 PMID:12931191 PMID:15231831 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:15901672) RGD PMID:15901672 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:16424160)
MGI:1857429 (PMID:12925707), (PMID:14507967)
MGI:2675387 (PMID:18436203)
GO_REF:0000024
RGD
UniProt
PMID:12925707 PMID:14507967 PMID:16424160 PMID:18436203 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO (PMID:11463392) RGD PMID:11463392 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of ISO MGI:99161 (PMID:11290297) RGD PMID:11290297 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of ISO (PMID:17367784) RGD PMID:17367784 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO (PMID:12477715), (PMID:16183742) RGD PMID:12477715 PMID:16183742 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
ISO (PMID:11101870)
(PMID:16183742)
RGD PMID:11101870 PMID:16183742 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:21382479)
GO_REF:0000107
RGD
Ensembl
PMID:21382479 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:14707049), (PMID:8920854), (PMID:8943715) RGD PMID:8920854 PMID:8943715 PMID:14707049 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:8666928) RGD PMID:8666928 NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
JBrowse link
G Cd5 Cd5 molecule involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:10429671)
Ensembl
RGD
PMID:10429671 GO_REF:0000107 NCBI chr 1:207,365,337...207,386,313
Ensembl chr 1:207,365,337...207,386,313
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO (PMID:8985253) RGD PMID:8985253 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:1858008|MGI:2148567|MGI:98957 (PMID:15131783), (PMID:20454446)
Ensembl
RGD
PMID:15131783 PMID:20454446 GO_REF:0000107 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Dap death-associated protein involved_in ISO
IBA
IEA
(PMID:1087798), (PMID:7828849)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:1087798 PMID:7828849 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:82,199,206...82,251,771
Ensembl chr 2:82,199,280...82,251,752
JBrowse link
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:7828849) RGD PMID:7828849 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1197015|MGI:2149961 (PMID:12917339), (PMID:9488481)
Ensembl
RGD
PMID:9488481 PMID:12917339 GO_REF:0000107 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558
JBrowse link
G Dapl1 death associated protein-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:1203520|MGI:2149961 (PMID:12917339) RGD PMID:12917339 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Dido1 death inducer-obliterator 1 acts_upstream_of_or_within ISO (PMID:10393935) RGD PMID:10393935 NCBI chr 3:167,772,535...167,825,894
Ensembl chr 3:167,772,770...167,817,218
JBrowse link
G ENSRNOG00000063234 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr15:17,205,053...17,206,176 JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:11101870), (PMID:8565075) RGD PMID:8565075 PMID:11101870 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of ISO MGI:4888719 (PMID:21209208) RGD PMID:21209208 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within IMP
ISO
(PMID:7511063), (PMID:8666928) RGD PMID:7511063 PMID:8666928 PMID:16953119 RGD:1600313 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand involved_in
acts_upstream_of_or_within
ISO (PMID:11101870)
(PMID:15629131), (PMID:7511063)
RGD PMID:7511063 PMID:11101870 PMID:15629131 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:11007801) RGD PMID:11007801 NCBI chr12:21,133,364...21,267,796
Ensembl chr12:21,133,406...21,267,725
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifi27l2b interferon, alpha-inducible protein 27 like 2B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of ISO UniProtKB:Q8WYH8 (PMID:21750715) RGD PMID:21750715 NCBI chr10:55,401,989...55,414,364
Ensembl chr10:55,401,982...55,414,114
JBrowse link
G Ing5 inhibitor of growth family, member 5 acts_upstream_of ISO MGI:2144284 (PMID:21750715) RGD PMID:21750715 NCBI chr 9:94,326,549...94,343,392
Ensembl chr 9:94,326,548...94,344,220
JBrowse link
G Inhbb inhibin subunit beta B involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:98957 (PMID:20454446)
Ensembl
RGD
PMID:20454446 GO_REF:0000107 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of ISO MGI:104798 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of ISO MGI:1346862 (PMID:16458303) RGD PMID:16458303 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:1346861 (PMID:16458303)
Ensembl
RGD
PMID:16458303 GO_REF:0000107 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:11060313) RGD PMID:11060313 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of ISO MGI:2682607|MGI:99702 (PMID:18436203) RGD PMID:18436203 NCBI chr19:23,978,465...23,988,933
Ensembl chr19:23,985,504...23,988,932
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:10924506) RGD PMID:10924506 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726
JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in ISO (PMID:17264311) RGD PMID:17264311 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253
JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in IDA PMID:12857854 BHF-UCL PMID:12857854 RGD:8554350 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:1197015|MGI:1203520 (PMID:12917339) RGD PMID:12917339 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028
JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of ISO MGI:88174 (PMID:11290297) RGD PMID:11290297 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISS
ISO
GO_REF:0000024
(PMID:31420216), (PMID:35104454)
UniProt
RGD
PMID:31420216 PMID:35104454 GO_REF:0000024 NCBI chr 4:174,172,804...174,443,944
Ensembl chr 4:174,172,868...174,438,274
JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within ISO MGI:1306796|MGI:1336168|MGI:97295 (PMID:16183742) RGD PMID:16183742 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta involved_in ISO (PMID:11551955) RGD PMID:11551955 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Psen1 presenilin 1 acts_upstream_of ISO MGI:109284 (PMID:15148382) RGD PMID:15148382 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 acts_upstream_of ISO MGI:1202717 (PMID:15148382) RGD PMID:15148382 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Ptgis prostaglandin I2 synthase involved_in ISO
IEA
(PMID:11551955)
GO_REF:0000107
RGD
Ensembl
PMID:11551955 GO_REF:0000107 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Senp1 SUMO specific peptidase 1 involved_in ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:14570870)
UniProt
Ensembl
RGD
PMID:14570870 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5559673|PMID:11044396)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:11044396 GO_REF:0000024 GO_REF:0000107 MGI:5559673 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
JBrowse link
G Slfn4 schlafen family member 4 involved_in ISO (PMID:31420216), (PMID:35104454) RGD PMID:31420216 PMID:35104454 NCBI chr10:67,994,601...68,018,141
Ensembl chr10:68,000,028...68,018,138
Ensembl chr10:68,000,028...68,018,138
JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G Tfpt TCF3 fusion partner involved_in ISO
IBA
IEA
(PMID:17041757)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
RGD
GO_Central
TreeGrafter
Ensembl
PMID:17041757 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:65,587,633...65,597,407
Ensembl chr 1:65,582,359...65,611,689
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794 (PMID:12872135) RGD PMID:12872135 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tm2d1 TM2 domain containing 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:11278849)
GO_Central
RGD
PMID:11278849 GO_REF:0000033 NCBI chr 5:113,020,793...113,062,134
Ensembl chr 5:113,020,760...113,050,933
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:15629131), (PMID:8208546) RGD PMID:8208546 PMID:15629131 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 involved_in IMP PMID:17998337 UniProt PMID:17998337 RGD:10047225 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO (PMID:28990932) RGD PMID:28990932 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
G Vdr vitamin D receptor IDA RGD PMID:9579411 RGD:70308 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of ISO MGI:88276|MGI:96571 (PMID:20454446) RGD PMID:20454446 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
apoptosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:20885443) RGD PMID:20885443 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:20885443)
Ensembl
RGD
PMID:20885443 GO_REF:0000107 NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) RGD PMID:15214043 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) RGD PMID:23728777 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
JBrowse link
death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO (PMID:24025841) RGD PMID:24025841 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2388026 (PMID:16365167)
Ensembl
RGD
PMID:16365167 GO_REF:0000107 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B involved_in ISO
IEA
(PMID:9884026)
GO_REF:0000107
RGD
Ensembl
PMID:9884026 GO_REF:0000107 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
IEA
IBA
(PMID:18852119)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:18852119 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) RGD PMID:15214043 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158671 (PMID:10476969)
Ensembl
RGD
PMID:10476969 GO_REF:0000107 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:104798|MGI:109324|MGI:1336166 (PMID:10588860), (PMID:12065591), (PMID:22089168), (PMID:22675671)
(PMID:21785459), (PMID:35446120)
(MGI:6401035|PMID:31748744)
UniProt
RGD
PMID:10588860 PMID:12065591 PMID:21785459 PMID:22089168 PMID:22675671 More... GO_REF:0000024 MGI:6401035 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cd27 CD27 molecule involved_in ISO (PMID:9177220) RGD PMID:9177220 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd70 Cd70 molecule involved_in ISO (PMID:9177220) RGD PMID:9177220 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715
JBrowse link
G Cttn cortactin involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:1924375 (PMID:22660580)
Ensembl
RGD
PMID:22660580 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of ISO (PMID:15734730) RGD PMID:15734730 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:16611992), (PMID:21785459)
MGI:1889507 (PMID:10588860), (PMID:16183742)
GO_REF:0000033
RGD
GO_Central
PMID:10588860 PMID:16183742 PMID:16611992 PMID:21785459 GO_REF:0000033 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor involved_in
acts_upstream_of_or_within
ISO (PMID:22891283)
(PMID:12011074), (PMID:17980593)
RGD PMID:12011074 PMID:17980593 PMID:22891283 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand involved_in ISO (PMID:22891283) RGD PMID:22891283 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19706769)
UniProt
RGD
PMID:19706769 GO_REF:0000024 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO UniProtKB:Q9WV60 (MGI:4818524|PMID:20371704) RGD PMID:20371704 MGI:4818524 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO UniProtKB:Q2NL51 (MGI:4818524|PMID:20371704) RGD PMID:20371704 MGI:4818524 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in ISO
IEA
(PMID:15701637)
GO_REF:0000107
RGD
Ensembl
PMID:15701637 GO_REF:0000107 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in ISO (PMID:24970806) RGD PMID:24970806 NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA
(PMID:16942485)
GO_REF:0000107
RGD
Ensembl
PMID:16942485 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il33 interleukin 33 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:99695 (PMID:22660580)
Ensembl
RGD
PMID:22660580 GO_REF:0000107 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:10429671) RGD PMID:10429671 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:10429671)
Ensembl
RGD
PMID:10429671 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Inhba inhibin subunit beta A involved_in ISO (PMID:9884026) RGD PMID:9884026 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (PMID:12426001) RGD PMID:12426001 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Krt18 keratin 18 acts_upstream_of_or_within ISO MGI:2178045 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt8 keratin 8 acts_upstream_of_or_within ISO MGI:2178042 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISS
ISO
GO_REF:0000024
(PMID:18852119)
UniProt
RGD
PMID:18852119 GO_REF:0000024 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 acts_upstream_of_or_within ISO (PMID:10924506) RGD PMID:10924506 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726
JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within
IDA
ISO
PMID:8614837
MGI:2386080 (PMID:17286969)
PMID:12857854
RGD PMID:17286969 PMID:8614837 PMID:12857854 RGD:69918, RGD:8554350 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 acts_upstream_of_or_within ISO (PMID:12065591) RGD PMID:12065591 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:15858817)
Ensembl
RGD
PMID:15858817 GO_REF:0000107 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA
(PMID:16207722)
GO_REF:0000107
RGD
Ensembl
PMID:16207722 GO_REF:0000107 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623
JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within ISO MGI:1261423 (PMID:16183742) RGD PMID:16183742 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO MGI:2429949 (PMID:9806545) RGD PMID:9806545 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:2668456 (PMID:15259009)
Ensembl
RGD
PMID:15259009 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of ISO MGI:3690329 (PMID:17015619) RGD PMID:17015619 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:10521396), (PMID:7538908), (PMID:8612133) RGD PMID:7538908 PMID:8612133 PMID:10521396 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:14765125) RGD PMID:14765125 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:3045799 (PMID:14976225)
Ensembl
RGD
PMID:14976225 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:12235122)
Ensembl
RGD
PMID:12235122 GO_REF:0000107 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO
IBA
IEA
(PMID:9177220)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:9177220 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (PMID:15334054) RGD PMID:15334054 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO
GO_REF:0000107
RNAcentral:URS0000554A4F_9606 (PMID:22821565)
Ensembl
RGD
PMID:22821565 GO_REF:0000107 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15334054), (PMID:26572508)
UniProt
RGD
PMID:15334054 PMID:26572508 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:17217916)
AgBase
RGD
PMID:17217916 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO (PMID:21737330) RGD PMID:21737330 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within
ISO (PMID:11577081), (PMID:16611992)
MGI:104798|MGI:108212|MGI:1261423 (PMID:19498109), (PMID:22089168)
RGD PMID:11577081 PMID:16611992 PMID:19498109 PMID:22089168 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b involved_in ISO (PMID:21785459) RGD PMID:21785459 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A acts_upstream_of_or_within ISO (PMID:12821115) RGD PMID:12821115 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000118
MGI:1857262 (PMID:7990930)
GO_REF:0000033
TreeGrafter
RGD
GO_Central
PMID:7990930 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:12821115)
GO_Central
RGD
PMID:12821115 GO_REF:0000033 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213
JBrowse link
G Tradd TNFRSF1A-associated via death domain involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:16611992)
MGI:104798|MGI:108212 (PMID:22089168)
GO_REF:0000033
RGD
GO_Central
PMID:16611992 PMID:22089168 GO_REF:0000033 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:95484 (PMID:17980593)
Ensembl
RGD
PMID:17980593 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
G Zfp110 zinc finger protein 110 acts_upstream_of_or_within ISO MGI:2156881 (PMID:10545116) RGD PMID:10545116 NCBI chr 1:73,445,303...73,461,112
Ensembl chr 1:73,445,336...73,461,086
JBrowse link
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07071210.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 8:97,646,513...97,647,024 JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1890081 (PMID:12115603), (PMID:12431371), (PMID:12944463), (PMID:14967141)
Ensembl
RGD
PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within ISO (PMID:11527400) RGD PMID:11527400 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1197519|MGI:99702 (PMID:15680329), (PMID:15967824)
GO_Central
RGD
PMID:15680329 PMID:15967824 GO_REF:0000033 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
GO_REF:0000033
MGI:1097161|MGI:1197519 (PMID:15680329), (PMID:15967824)
GO_REF:0000118
GO_Central
RGD
TreeGrafter
PMID:15680329 PMID:15967824 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baxl1 BCL2-associated X protein like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:86,524,658...86,533,056
Ensembl chr10:86,532,281...86,532,859
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:1309517 (PMID:12082633)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:12082633 GO_REF:0000033 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
GO_REF:0000033
(PMID:12115603)
GO_REF:0000118
GO_Central
RGD
TreeGrafter
PMID:12115603 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in
acts_upstream_of
IBA
ISO
GO_REF:0000033
(PMID:9878060)
GO_Central
RGD
PMID:9878060 GO_REF:0000033 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:1097161|MGI:2156498|MGI:99702 (PMID:15967824) RGD PMID:15967824 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:12115603)
GO_Central
RGD
PMID:12115603 GO_REF:0000033 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Casp2 caspase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2159368 (PMID:11536012)
GO_Central
RGD
PMID:11536012 GO_REF:0000033 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:2152978 (PMID:9299161)
Ensembl
RGD
PMID:9299161 GO_REF:0000107 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of ISO (PMID:18322241), (PMID:18971423) RGD PMID:18322241 PMID:18971423 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G ENSRNOG00000064151 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 3:138,869,480...138,870,482 JBrowse link
G ENSRNOG00000070080 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 3:138,335,033...138,336,404 JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in ISO
IEA
(PMID:17701904)
GO_REF:0000107
RGD
Ensembl
PMID:17701904 GO_REF:0000107 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of ISO MGI:1857803 (PMID:15817220) RGD PMID:15817220 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO (PMID:11700312) RGD PMID:11700312 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within ISO (PMID:13679421) RGD PMID:13679421 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000118
MGI:1856334|MGI:1861923 (PMID:13679421)
GO_REF:0000033
TreeGrafter
RGD
GO_Central
PMID:13679421 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of ISO MGI:1859647 (PMID:16956603) RGD PMID:16956603 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO MGI:1096330 (PMID:12431371) RGD PMID:12431371 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:5514334|PMID:16543145)
UniProt
GO_Central
Ensembl
RGD
PMID:16543145 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5514334 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
(MGI:5514334|PMID:16543145)
UniProt
GO_Central
TreeGrafter
RGD
PMID:16543145 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5514334 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (PMID:12431371) RGD PMID:12431371 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il1a interleukin 1 alpha involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2157371 (PMID:11536012)
Ensembl
RGD
PMID:11536012 GO_REF:0000107 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2157396 (PMID:11536012)
Ensembl
RGD
PMID:11536012 GO_REF:0000107 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:12082633) RGD PMID:12082633 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:11527400), (PMID:12124386), (PMID:12944463), (PMID:14967141), (PMID:15231831), (PMID:15680329) RGD PMID:11527400 PMID:12124386 PMID:12944463 PMID:14967141 PMID:15231831 More... NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12115603) RGD PMID:12115603 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (MGI:3530680|PMID:15591537) RGD PMID:15591537 MGI:3530680 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO (PMID:15039234) RGD PMID:15039234 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Lcn2 lipocalin 2 acts_upstream_of_or_within ISO (PMID:16377569) RGD PMID:16377569 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(MGI:5514334|PMID:16543145)
(PMID:16543145)
UniProt
GO_Central
RGD
PMID:16543145 GO_REF:0000024 GO_REF:0000033 MGI:5514334 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO MGI:3052673|MGI:894279 (PMID:17903173) RGD PMID:17903173 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3052675|MGI:894316 (PMID:17903173)
Ensembl
RGD
PMID:17903173 GO_REF:0000107 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:1857478 (PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Ngf nerve growth factor acts_upstream_of_or_within ISO (PMID:14623868) RGD PMID:14623868 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of ISO (PMID:8206089) RGD PMID:8206089 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,802,968...198,823,032
Ensembl chr 1:198,802,971...198,823,418
JBrowse link
extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3029528 (PMID:12431371)
Ensembl
RGD
PMID:12431371 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within ISO (PMID:10597216) RGD PMID:10597216 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (PMID:10597216) RGD PMID:10597216 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:10597216)
GO_REF:0000107
RGD
Ensembl
PMID:10597216 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bex3 brain expressed X-linked 3 acts_upstream_of_or_within ISO PR:Q9Z0W1 (PMID:10764727) RGD PMID:10764727 NCBI chr  X:99,273,270...99,274,799
Ensembl chr  X:99,273,161...99,274,800
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
IEA
ISS
(PMID:18188704)
GO_REF:0000107
RGD
Ensembl
PMID:18188704 PMID:18188704 GO_REF:0000107, RGD:8553738 NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2177602|MGI:3054930 (PMID:15322156)
GO_Central
RGD
PMID:15322156 GO_REF:0000033 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17245429)
(PMID:10235259)
GO_REF:0000033
RGD
GO_Central
PMID:10235259 PMID:17245429 GO_REF:0000033 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
(PMID:19903888)
GO_REF:0000107
RGD
Ensembl
PMID:19903888 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within ISO MGI:3042776|MGI:3052030 (PMID:15010850), (PMID:20053891) RGD PMID:15010850 PMID:20053891 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
JBrowse link
G Daxx death-domain associated protein involved_in ISO
IEA
(PMID:9215629)
GO_REF:0000107
RGD
Ensembl
PMID:9215629 GO_REF:0000107 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Ddx47 DEAD-box helicase 47 involved_in ISO (PMID:15977068) RGD PMID:15977068 NCBI chr 4:167,845,652...167,858,115
Ensembl chr 4:167,845,640...167,859,115
JBrowse link
G Dedd death effector domain-containing involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:9774341)
GO_Central
RGD
PMID:9774341 GO_REF:0000033 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332
JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO
IBA
(PMID:11741985)
GO_REF:0000033
RGD
GO_Central
PMID:11741985 GO_REF:0000033 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO
IBA
ISS
(PMID:20563667)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:20563667 GO_REF:0000024 GO_REF:0000033 NCBI chr18:30,085,093...30,098,105
Ensembl chr18:30,085,126...30,098,756
JBrowse link
G Fadd Fas associated via death domain involved_in ISO (PMID:24025841) RGD PMID:24025841 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor involved_in
acts_upstream_of_or_within
ISO (MGI:5009197|PMID:10950869)
MGI:1096330|MGI:1856334 (PMID:10429671), (PMID:10588860), (PMID:12431371), (PMID:12801066), (PMID:15039234), (PMID:15632112), (PMID:18363966), (PMID:8524870)
RGD PMID:8524870 PMID:10429671 PMID:10588860 PMID:10950869 PMID:12431371 More... MGI:5009197 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand acts_upstream_of_or_within
involved_in
IMP
ISO
IBA
(PMID:10588860), (PMID:15039234)
GO_REF:0000033
(PMID:26582200)
(PMID:18835034)
RGD
GO_Central
PMID:10588860 PMID:15039234 PMID:18835034 PMID:26582200 PMID:16689665 GO_REF:0000033, RGD:1582444 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO
GO_REF:0000024
(PMID:15977068)
UniProt
RGD
PMID:15977068 GO_REF:0000024 NCBI chr10:54,714,777...54,718,099
Ensembl chr10:54,714,198...54,717,765
JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of ISO MGI:2387671 (PMID:19139395) RGD PMID:19139395 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:11131641)
(PMID:11429161)
RGD PMID:11131641 PMID:11429161 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of ISO MGI:1916885 (PMID:20053891) RGD PMID:20053891 NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857478|MGI:97583 (PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Ngf nerve growth factor involved_in ISO
IEA
(PMID:14985763)
GO_REF:0000107
RGD
Ensembl
PMID:14985763 GO_REF:0000107 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within ISO MGI:109324 (PMID:16183742) RGD PMID:16183742 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:97306 (PMID:15039234)
Ensembl
RGD
PMID:15039234 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:2388026|MGI:95484|MGI:99255 (PMID:16365167)
Ensembl
RGD
PMID:16365167 GO_REF:0000107 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within ISO MGI:95484|MGI:97847 (PMID:16365167) RGD PMID:16365167 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of ISO MGI:2387096 (PMID:10811619) RGD PMID:10811619 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Sort1 sortilin 1 involved_in ISO
IEA
(PMID:14985763)
GO_REF:0000107
RGD
Ensembl
PMID:14985763 GO_REF:0000107 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
JBrowse link
G Stk3 serine/threonine kinase 3 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:1928487|MGI:1929004 (PMID:20080598)
Ensembl
RGD
PMID:20080598 GO_REF:0000107 NCBI chr 7:66,053,209...66,323,292
Ensembl chr 7:66,052,345...66,323,233
JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of ISO MGI:104798|MGI:1928487 (PMID:20080598) RGD PMID:20080598 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744
JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within
ISO
IBA
IEA
(PMID:10521396), (PMID:18202225), (PMID:18676776)
MGI:1096330|MGI:1928487|MGI:1929004 (PMID:12431371), (PMID:20080598)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:10521396 PMID:12431371 PMID:18202225 PMID:18676776 PMID:20080598 GO_REF:0000033 GO_REF:0000118 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b IMP RGD PMID:19934367 RGD:4142856 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467
JBrowse link
fibroblast growth factor receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:16720875) RGD PMID:16720875 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (PMID:16720875) RGD PMID:16720875 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (PMID:17561467) RGD PMID:17561467 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
granzyme-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ube4b ubiquitination factor E4B involved_in ISO (PMID:11802788) RGD PMID:11802788 NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509
JBrowse link
hormone-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA RGD PMID:11790788 RGD:1358682 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Esr2 estrogen receptor 2 acts_upstream_of_or_within ISO MGI:2152217 (PMID:15187231) RGD PMID:15187231 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Mettl21c methyltransferase 21C, AARS1 lysine acts_upstream_of_or_within ISO (PMID:24677265) RGD PMID:24677265 NCBI chr 9:46,130,451...46,145,128
Ensembl chr 9:46,134,001...46,145,112
JBrowse link
intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISS
IEA
IBA
ISO
GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
(PMID:18676776)
UniProt
TreeGrafter
GO_Central
RGD
PMID:18676776 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO (PMID:22006182) RGD PMID:22006182 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of
ISS
ISO
GO_REF:0000024
MGI:2158306 (PMID:14502238)
(PMID:16462759), (PMID:9219694)
UniProt
RGD
PMID:9219694 PMID:14502238 PMID:16462759 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO (PMID:17024184) RGD PMID:17024184 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bnip3 BCL2 interacting protein 3 acts_upstream_of_or_within ISO MGI:96224 (PMID:16954213) RGD PMID:16954213 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of ISO MGI:3793294 (PMID:17938250) RGD PMID:17938250 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Casp12 caspase 12 involved_in IMP PMID:10638761 ParkinsonsUK-UCL PMID:10638761 RGD:10047306 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 involved_in ISO (PMID:15565177) RGD PMID:15565177 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:15123740) RGD PMID:15123740 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp9 caspase 9 involved_in ISO (PMID:35446120) RGD PMID:35446120 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Clu clusterin involved_in ISO
ISS
(PMID:21567405)
GO_REF:0000024
RGD
UniProt
PMID:21567405 GO_REF:0000024 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Coa8 cytochrome c oxidase assembly factor 8 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
(PMID:16782708)
InterPro
RGD
PMID:16782708 GO_REF:0000002 NCBI chr 6:130,772,218...130,797,081
Ensembl chr 6:130,771,199...130,797,081
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:16301996) RGD PMID:16301996 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Flcn folliculin acts_upstream_of ISO MGI:4348628 (PMID:21258407) RGD PMID:21258407 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:109326 (PMID:16954213) RGD PMID:16954213 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Htra2 HtrA serine peptidase 2 acts_upstream_of_or_within ISO MGI:3512633 (PMID:15509788) RGD PMID:15509788 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of ISO MGI:4820513 (PMID:15485691) RGD PMID:15485691 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Lgals12 galectin 12 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:11435439)
GO_REF:0000033
RGD
GO_Central
PMID:11435439 GO_REF:0000033 NCBI chr 1:204,832,065...204,842,759
Ensembl chr 1:204,832,065...204,842,759
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISO
ISS
(PMID:18852119)
GO_REF:0000024
RGD
UniProt
PMID:18852119 GO_REF:0000024 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:2151803 (PMID:14632208) RGD PMID:14632208 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Nbn nibrin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3027036 (PMID:18614044)
Ensembl
RGD
PMID:18614044 GO_REF:0000107 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:5573029|PMID:24312627)
Ensembl
RGD
PMID:24312627 GO_REF:0000107 MGI:5573029 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO (MGI:5315351|PMID:15863367) RGD PMID:15863367 MGI:5315351 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711) RGD PMID:14500711 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F involved_in ISO
ISS
(PMID:11559703)
GO_REF:0000024
RGD
UniProt
PMID:11559703 GO_REF:0000024 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340
JBrowse link
G Prkca protein kinase C, alpha acts_upstream_of_or_within ISO MGI:3029711 (PMID:12928424) RGD PMID:12928424 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:10859351)
Ensembl
RGD
PMID:10859351 GO_REF:0000107 NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23313858) RGD PMID:23313858 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor NOT|involved_in ISO (PMID:12011449) RGD PMID:12011449 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO (PMID:10479688) RGD PMID:10479688 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO (PMID:15102863) RGD PMID:15102863 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS
(PMID:22858542)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:22858542 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of ISO MGI:98834 (PMID:26158450) RGD PMID:26158450 NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177
JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO (PMID:15660129) RGD PMID:15660129 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283
JBrowse link
G E2f1 E2F transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:11095619)
Ensembl
RGD
PMID:11095619 GO_REF:0000107 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f2 E2F transcription factor 2 acts_upstream_of_or_within ISO (PMID:11095619) RGD PMID:11095619 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G Eda2r ectodysplasin A2 receptor acts_upstream_of_or_within ISO MGI:98834 (PMID:20434500) RGD PMID:20434500 NCBI chr  X:62,224,763...62,269,333
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO MGI:2183949 (PMID:18545656) RGD PMID:18545656 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:15313915)
UniProt
GO_Central
TreeGrafter
Ensembl
RGD
PMID:15313915 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 involved_in ISO
ISS
(PMID:16835243)
GO_REF:0000024
RGD
UniProt
PMID:16835243 GO_REF:0000024 NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568
JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:10518217)
GO_Central
RGD
PMID:10518217 GO_REF:0000033 NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006
JBrowse link
G Mybbp1a MYB binding protein 1a involved_in ISO
IEA
(PMID:21471221)
GO_REF:0000107
RGD
Ensembl
PMID:21471221 GO_REF:0000107 NCBI chr10:57,056,897...57,067,258
Ensembl chr10:57,056,874...57,067,255
JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO
IEA
(PMID:22123926)
GO_REF:0000107
RGD
Ensembl
PMID:22123926 GO_REF:0000107 NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
JBrowse link
G Perp p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO (PMID:10733530) RGD PMID:10733530 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(MGI:2679929|PMID:14500851)
RGD PMID:14500851 PMID:15102863 MGI:2679929 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO (PMID:14992722) RGD PMID:14992722 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5825431|PMID:17145718)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17145718 GO_REF:0000024 GO_REF:0000107 MGI:5825431 NCBI chr15:81,253,714...81,260,057
Ensembl chr15:81,257,781...81,259,728
JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5825431|PMID:17145718)
UniProt
RGD
PMID:17145718 GO_REF:0000024 MGI:5825431 NCBI chr19:29,486,686...29,490,327
Ensembl chr19:29,486,686...29,490,327
JBrowse link
G Ppp1r13b protein phosphatase 1, regulatory subunit 13B involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr 6:130,890,682...130,963,845
Ensembl chr 6:130,890,679...130,963,330
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of ISO MGI:3584037 (PMID:15989966) RGD PMID:15989966 NCBI chr10:2,129,949...2,165,381
Ensembl chr10:2,129,978...2,165,663
JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISO
IEA
(PMID:21471221)
GO_REF:0000107
RGD
Ensembl
PMID:21471221 GO_REF:0000107 NCBI chr 1:160,081,092...160,088,709
Ensembl chr 1:160,084,295...160,089,331
JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO (PMID:12135983) RGD PMID:12135983 NCBI chr 8:109,691,504...109,706,411
Ensembl chr 8:109,691,522...109,706,408
JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO
ISS
(PMID:11430832)
GO_REF:0000024
RGD
UniProt
PMID:11430832 GO_REF:0000024 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO (PMID:12172011), (PMID:16322561), (PMID:17310983)
MGI:2442860 (PMID:12135983), (PMID:16107883), (PMID:20434500)
RGD PMID:12135983 PMID:12172011 PMID:16107883 PMID:16322561 PMID:17310983 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432
JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO MGI:98834 (PMID:11058590) RGD PMID:11058590 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
G Zfp385b zinc finger protein 385B involved_in ISO (PMID:22945289) RGD PMID:22945289 NCBI chr 3:62,355,182...62,640,417
Ensembl chr 3:62,355,196...62,640,510
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07071210.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 8:97,646,513...97,647,024 JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:1328356|MGI:88138 (PMID:15983387) RGD PMID:15983387 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Atm ATM serine/threonine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:109337|MGI:1933746 (PMID:11040211), (PMID:16777961), (PMID:17476307)
GO_Central
RGD
PMID:11040211 PMID:16777961 PMID:17476307 GO_REF:0000033 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3029528 (PMID:12431371), (PMID:15231831)
Ensembl
RGD
PMID:12431371 PMID:15231831 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1197519|MGI:99702 (PMID:15901672), (PMID:15967824)
GO_Central
RGD
PMID:15901672 PMID:15967824 GO_REF:0000033 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000118
MGI:1097161|MGI:1197519|MGI:1857429 (PMID:12952892), (PMID:15901672), (PMID:15967824)
GO_REF:0000033
TreeGrafter
RGD
GO_Central
PMID:12952892 PMID:15901672 PMID:15967824 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Baxl1 BCL2-associated X protein like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr10:86,524,658...86,533,056
Ensembl chr10:86,532,281...86,532,859
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:2442925 (PMID:15983387)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:15983387 GO_REF:0000033 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000118
MGI:2158303 (PMID:14517295)
GO_REF:0000033
TreeGrafter
RGD
GO_Central
PMID:14517295 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:11546872)
MGI:1097161|MGI:99702 (PMID:15967824)
GO_REF:0000107
RGD
Ensembl
PMID:11546872 PMID:15967824 GO_REF:0000107 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Brca1 BRCA1, DNA repair associated acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:14654789)
GO_REF:0000107
RGD
Ensembl
PMID:14654789 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated acts_upstream_of_or_within ISO MGI:107202 (PMID:17476307) RGD PMID:17476307 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Casp2 caspase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp9 caspase 9 involved_in ISO
IBA
(PMID:15657060)
GO_REF:0000033
RGD
GO_Central
PMID:15657060 GO_REF:0000033 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Casp9_v1 caspase-9-carboxyl-terminal divergent involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Chek2 checkpoint kinase 2 involved_in ISO (PMID:12402044), (PMID:12717439), (PMID:18644861) RGD PMID:12402044 PMID:12717439 PMID:18644861 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Crip1 cysteine rich protein 1 involved_in ISS
IEA
IBA
ISO
PMID:20415737
GO_REF:0000118
GO_REF:0000033
(PMID:20415737)
TreeGrafter
GO_Central
RGD
PMID:20415737 PMID:20415737 GO_REF:0000033 GO_REF:0000118, RGD:8553326 NCBI chr 6:132,226,746...132,234,620
Ensembl chr 6:132,226,746...132,234,620
JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO
IEA
ISS
(PMID:12717439)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12717439 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO (PMID:10594026) RGD PMID:10594026 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571
JBrowse link
G ENSRNOG00000064151 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 3:138,869,480...138,870,482 JBrowse link
G ENSRNOG00000070080 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 3:138,335,033...138,336,404 JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:18339848) RGD PMID:18339848 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO MGI:1932102 (PMID:11005836) RGD PMID:11005836 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Fnip2 folliculin interacting protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5284752|PMID:19137017)
UniProt
RGD
PMID:19137017 GO_REF:0000024 MGI:5284752 NCBI chr 2:164,596,557...164,708,147
Ensembl chr 2:164,598,906...164,707,901
JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (PMID:16269335)
(MGI:5297787|PMID:16269335)
RGD PMID:16269335 MGI:5297787 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:11854317 RGD:625692 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:11602612) RGD PMID:11602612 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO (PMID:11753682) RGD PMID:11753682 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:20188669) RGD PMID:20188669 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143
JBrowse link
G Mael maelstrom spermatogenic transposon silencer acts_upstream_of_or_within ISO MGI:3795667 (PMID:18694567) RGD PMID:18694567 NCBI chr13:78,457,073...78,496,657
Ensembl chr13:78,457,073...78,496,657
JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase acts_upstream_of_or_within ISO MGI:2183491 (PMID:14562041) RGD PMID:14562041 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:15901672)
GO_Central
RGD
PMID:15901672 GO_REF:0000033 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mlh1 mutL homolog 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857946 (PMID:14562041)
Ensembl
RGD
PMID:14562041 GO_REF:0000107 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643
JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO MGI:1858055|MGI:2680817 (PMID:10097137), (PMID:14744764) RGD PMID:10097137 PMID:14744764 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO MGI:1858014 (PMID:15324697) RGD PMID:15324697 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (PMID:14517295) RGD PMID:14517295 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO MGI:97583 (PMID:17242187) RGD PMID:17242187 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610
JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) RGD PMID:10891498 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:104798|MGI:2149414 (PMID:17242187)
Ensembl
RGD
PMID:17242187 GO_REF:0000107 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO MGI:2678372 (PMID:12952892) RGD PMID:12952892 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pml PML nuclear body scaffold involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:12402044)
MGI:104662|MGI:2429949 (PMID:15626733), (PMID:9806545)
GO_REF:0000033
RGD
GO_Central
PMID:9806545 PMID:12402044 PMID:15626733 GO_REF:0000033 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO (PMID:10197627) RGD PMID:10197627 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1857113 (PMID:12604618)
GO_Central
RGD
PMID:12604618 GO_REF:0000033 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of ISO MGI:2442925 (PMID:15983387) RGD PMID:15983387 NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608
JBrowse link
G Sfn stratifin involved_in ISO (PMID:11574543) RGD PMID:11574543 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(MGI:5297787|PMID:16269335)
GO_REF:0000107
RGD
Ensembl
PMID:16269335 GO_REF:0000107 MGI:5297787 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of ISO MGI:2387096 (PMID:10811619) RGD PMID:10811619 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857480 (PMID:15642323) RGD PMID:15642323 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:17242187) RGD PMID:17242187 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A acts_upstream_of_or_within ISO (PMID:17242187) RGD PMID:17242187 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000118
(PMID:17242187)
GO_REF:0000033
TreeGrafter
RGD
GO_Central
PMID:17242187 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in ISO (PMID:20188669) RGD PMID:20188669 NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO MGI:3043446 (PMID:15271982) RGD PMID:15271982 NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789
JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of ISO MGI:4130032 (PMID:19966869) RGD PMID:19966869 NCBI chr 1:166,152,104...166,235,312
Ensembl chr 1:166,152,199...166,235,312
JBrowse link
G Xpa XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:1857939 (PMID:11005836) RGD PMID:11005836 NCBI chr 5:60,431,673...60,475,726
Ensembl chr 5:60,431,673...60,475,726
JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:18264133)
UniProt
GO_Central
RGD
PMID:18264133 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:1336991|MGI:98834 (PMID:15983387) RGD PMID:15983387 NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17403783)
UniProt
Ensembl
RGD
PMID:17403783 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2681654 (PMID:16151013)
Ensembl
RGD
PMID:16151013 GO_REF:0000107 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Brca2 BRCA2, DNA repair associated involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2429691|MGI:3052655|MGI:98834 (PMID:15735671), (PMID:17476307)
Ensembl
RGD
PMID:15735671 PMID:17476307 GO_REF:0000107 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Cdip1 cell death-inducing p53 target 1 acts_upstream_of_or_within
involved_in
ISO
IBA
IEA
(PMID:17599062)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:17599062 GO_REF:0000033 GO_REF:0000107 NCBI chr10:10,773,538...10,796,979
Ensembl chr10:10,774,705...10,796,980
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:1933751 (PMID:12952892) RGD PMID:12952892 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO MGI:2386905 (PMID:10710310) RGD PMID:10710310 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5298149|PMID:21896779)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21896779 GO_REF:0000024 GO_REF:0000107 MGI:5298149 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in ISO (PMID:17349958) RGD PMID:17349958 NCBI chr 7:54,348,724...54,381,363
Ensembl chr 7:54,349,610...54,380,106
JBrowse link
G Ell3 elongation factor for RNA polymerase II 3 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:22768269)
Ensembl
RGD
PMID:22768269 GO_REF:0000107 NCBI chr 3:108,413,035...108,417,181
Ensembl chr 3:108,410,448...108,417,132
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:17403783) RGD PMID:17403783 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:1314872|MGI:98834 (PMID:16537918)
GO_REF:0000033
GO_REF:0000118
Ensembl
RGD
GO_Central
TreeGrafter
PMID:16537918 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:1314872|MGI:98834 (PMID:16537918) RGD PMID:16537918 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Msh2 mutS homolog 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:98834 (PMID:10097137)
Ensembl
RGD
PMID:10097137 GO_REF:0000107 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator acts_upstream_of_or_within ISO MGI:3784016 (PMID:11896600) RGD PMID:11896600 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 involved_in ISO
IBA
ISS
(PMID:19203586)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:19203586 GO_REF:0000024 GO_REF:0000033 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:10807576)
Ensembl
RGD
PMID:10807576 GO_REF:0000107 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pml PML nuclear body scaffold involved_in ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO (PMID:17057733), (PMID:18056458) RGD PMID:17057733 PMID:18056458 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418
JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO (PMID:12135983) RGD PMID:12135983 NCBI chr 8:109,691,504...109,706,411
Ensembl chr 8:109,691,522...109,706,408
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20100829) RGD PMID:20100829 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:21460037) RGD PMID:21460037 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536
JBrowse link
G Tmem109 transmembrane protein 109 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:4453832 (PMID:20060811)
GO_REF:0000033
GO_REF:0000118
Ensembl
RGD
GO_Central
TreeGrafter
PMID:20060811 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215
JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase acts_upstream_of_or_within ISO (PMID:15735665) RGD PMID:15735665 NCBI chr 5:55,388,033...55,399,937
Ensembl chr 5:55,387,632...55,399,937
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
ISO
IEA
(MGI:4944151|PMID:20818388), (MGI:5882892|PMID:16213212)
MGI:109337|MGI:1096393|MGI:1336991|MGI:1857263|MGI:1926340|MGI:2442925 (PMID:12135983), (PMID:12952892), (PMID:15983387), (PMID:16286009), (PMID:16777961), (PMID:17476307)
GO_REF:0000107
(PMID:14654789), (PMID:14744935)
(PMID:16213212), (PMID:17403783)
RGD
Ensembl
PMID:12135983 PMID:12952892 PMID:14654789 PMID:14744935 PMID:15983387 More... GO_REF:0000107 MGI:4944151 MGI:5882892 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934269 (PMID:17122775) RGD PMID:17122775 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tp73 tumor protein p73 involved_in
acts_upstream_of
ISO (PMID:18174154), (PMID:19490146)
MGI:2442925|MGI:98834 (PMID:15983387)
RGD PMID:15983387 PMID:18174154 PMID:19490146 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO
ISS
(PMID:16901786)
GO_REF:0000024
RGD
UniProt
PMID:16901786 GO_REF:0000024 NCBI chr 8:49,325,766...49,386,229
Ensembl chr 8:49,325,867...49,386,229
JBrowse link
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07005775.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Aifm1 apoptosis inducing factor, mitochondria associated 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3774040|PMID:18056262)
UniProt
RGD
PMID:18056262 GO_REF:0000024 MGI:3774040 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in ISO (MGI:5621265|PMID:16407291) RGD PMID:16407291 MGI:5621265 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
ISO
GO_REF:0000024
(MGI:4879048|PMID:21159964), (MGI:5496937|PMID:23624402)
UniProt
RGD
PMID:21159964 PMID:23624402 GO_REF:0000024 MGI:4879048 MGI:5496937 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO
IEA
(PMID:19061639)
GO_REF:0000107
RGD
Ensembl
PMID:19061639 GO_REF:0000107 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in ISO
IEA
(PMID:16725111)
GO_REF:0000107
RGD
Ensembl
PMID:16725111 GO_REF:0000107 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:3774040|PMID:18056262)
UniProt
Ensembl
RGD
PMID:18056262 GO_REF:0000024 GO_REF:0000107 MGI:3774040 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO MGI:99702|UniProtKB:P10415 (PMID:12847083), (PMID:15776018) RGD PMID:12847083 PMID:15776018 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:1097161|UniProtKB:P10415 (PMID:12847083), (PMID:15776018)
(PMID:16645094)
UniProt
RGD
PMID:12847083 PMID:15776018 PMID:16645094 GO_REF:0000024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:16407291)
(MGI:4879048|PMID:21159964), (MGI:5448480|PMID:22761832), (MGI:5621265|PMID:16407291)
UniProt
GO_Central
Ensembl
RGD
PMID:16407291 PMID:21159964 PMID:22761832 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:4879048 MGI:5448480 MGI:5621265 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:15776018)
GO_REF:0000107
RGD
Ensembl
PMID:15776018 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISO
IEA
(PMID:22713462)
GO_REF:0000107
RGD
Ensembl
PMID:22713462 GO_REF:0000107 NCBI chr 1:197,035,505...197,088,624
Ensembl chr 1:197,035,633...197,088,092
JBrowse link
G Casp12 caspase 12 involved_in
acts_upstream_of_or_within
NAS
ISO
IEA
PMID:10638761
MGI:1097161|MGI:99702 (PMID:12847083)
GO_REF:0000107
(MGI:1351404|PMID:10638761), (MGI:5634893|PMID:12097332)
RGD
Ensembl
PMID:10638761 PMID:12097332 PMID:12847083 PMID:10638761 GO_REF:0000107 MGI:1351404 MGI:5634893, RGD:10047306 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:15123740) RGD PMID:15123740 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISO
IEA
(MGI:1335331|PMID:9531536)
GO_REF:0000107
RGD
Ensembl
PMID:9531536 GO_REF:0000107 MGI:1335331 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO (PMID:19109178) RGD PMID:19109178 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA
(MGI:3796479|PMID:18281285)
GO_REF:0000107
RGD
Ensembl
PMID:18281285 GO_REF:0000107 MGI:3796479 NCBI chr 3:18,915,290...19,086,282
Ensembl chr 3:18,915,290...19,086,280
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in
acts_upstream_of_or_within
ISS
ISO
IBA
IEA
GO_REF:0000024
MGI:2179046 (PMID:11854325)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(MGI:1335331|PMID:9531536), (MGI:4879048|PMID:21159964), (MGI:5496937|PMID:23624402)
(PMID:15322075), (PMID:18940792), (PMID:20829347)
UniProt
RGD
GO_Central
TreeGrafter
Ensembl
PMID:9531536 PMID:11854325 PMID:15322075 PMID:18940792 PMID:20829347 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:1335331 MGI:4879048 MGI:5496937 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 involved_in ISO (PMID:19122239) RGD PMID:19122239 NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (PMID:11430819) RGD PMID:11430819 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(MGI:3840374|PMID:19328063)
(PMID:11146108)
GO_REF:0000033
RGD
GO_Central
PMID:11146108 PMID:19328063 GO_REF:0000033 MGI:3840374 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:9755171)
GO_Central
RGD
PMID:9755171 GO_REF:0000033 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha involved_in ISS
ISO
GO_REF:0000024
(MGI:4366390|PMID:19752026)
UniProt
RGD
PMID:19752026 GO_REF:0000024 MGI:4366390 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (MGI:5619738|PMID:23028846) RGD PMID:23028846 MGI:5619738 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Ins2 insulin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857572 (PMID:11854325)
Ensembl
RGD
PMID:11854325 GO_REF:0000107 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:4366390|PMID:19752026)
UniProt
Ensembl
RGD
PMID:19752026 GO_REF:0000024 GO_REF:0000107 MGI:4366390 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO (MGI:5616327|PMID:12050113) RGD PMID:12050113 MGI:5616327 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of ISO MGI:2181360 (PMID:20811152) RGD PMID:20811152 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO
IEA
(MGI:5621265|PMID:16407291)
GO_REF:0000107
RGD
Ensembl
PMID:16407291 GO_REF:0000107 MGI:5621265 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO (PMID:21030605) RGD PMID:21030605 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Qrich1 glutamine-rich 1 involved_in ISO (PMID:33384352) RGD PMID:33384352 NCBI chr 8:109,216,900...109,256,472
Ensembl chr 8:109,217,376...109,261,359
JBrowse link
G Rnf186 ring finger protein 186 involved_in ISO
IBA
(PMID:23896122)
GO_REF:0000033
RGD
GO_Central
PMID:23896122 GO_REF:0000033 NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716
JBrowse link
G Selenok selenoprotein K involved_in ISO (PMID:20692228) RGD PMID:20692228 NCBI chr16:5,152,066...5,160,648
Ensembl chr16:5,152,066...5,159,188
JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of ISO MGI:102851 (PMID:20811152) RGD PMID:20811152 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955
JBrowse link
G Syvn1 synoviolin 1 acts_upstream_of ISO MGI:2679656 (PMID:15611074) RGD PMID:15611074 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within ISO MGI:3052422 (PMID:15304216) RGD PMID:15304216 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Tmem117 transmembrane protein 117 involved_in ISO (PMID:28285135) RGD PMID:28285135 NCBI chr 7:125,757,591...126,219,692
Ensembl chr 7:125,757,591...126,219,690
JBrowse link
G Tmem238l transmembrane protein 238 like involved_in ISO (PMID:33112233) RGD PMID:33112233 NCBI chr10:51,647,871...51,662,206 JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA
(MGI:5621265|PMID:16407291)
GO_REF:0000107
RGD
Ensembl
PMID:16407291 GO_REF:0000107 MGI:5621265 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:15775988)
UniProt
RGD
PMID:15775988 GO_REF:0000024 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K acts_upstream_of_or_within IMP PMID:18710920 MGI PMID:18710920 RGD:8554156 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:3840374 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k4 mitogen activated protein kinase kinase 4 involved_in ISO (MGI:5770039|PMID:24705900) RGD PMID:24705900 MGI:5770039 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA
UniProtKB:O00506 (PMID:22652780)
GO_REF:0000107
RGD
Ensembl
PMID:22652780 GO_REF:0000107 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO UniProtKB:Q9BUL8 (PMID:22652780) RGD PMID:22652780 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244
JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in IEA
ISO
GO_REF:0000107
MGI:1857283 (PMID:17189429)
Ensembl
RGD
PMID:17189429 GO_REF:0000107 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO (PMID:20436456) RGD PMID:20436456 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:20935145)
Ensembl
RGD
PMID:20935145 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
intrinsic apoptotic signaling pathway in response to nitrosative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 involved_in ISO (MGI:5784990|PMID:14752510) RGD PMID:14752510 MGI:5784990 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 involved_in ISO (PMID:21716255)
(MGI:5474549|PMID:21716255)
RGD PMID:21716255 MGI:5474549 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 acts_upstream_of_or_within
involved_in
ISS
ISO
IEA
GO_REF:0000024
MGI:2180186 (PMID:10827969)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:10827969 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:98834|MGI:99702 (PMID:16571598)
Ensembl
RGD
PMID:16571598 GO_REF:0000107 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
JBrowse link
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 involved_in ISO
IEA
(PMID:18387645)
GO_REF:0000107
RGD
Ensembl
PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:12855558)
Ensembl
RGD
PMID:12855558 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5492227|PMID:23568032), (MGI:5544856|PMID:23979599)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:23568032 PMID:23979599 GO_REF:0000024 GO_REF:0000107 MGI:5492227 MGI:5544856 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:16085184)
GO_Central
RGD
PMID:16085184 GO_REF:0000033 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Diablol1 diablo, IAP-binding mitochondrial protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:141,744,994...141,746,345
Ensembl chr 5:141,744,961...141,746,356
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in
acts_upstream_of
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2158814 (PMID:16373599)
MGI:2158814 (PMID:11562367), (PMID:15663476)
Ensembl
RGD
PMID:11562367 PMID:15663476 PMID:16373599 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gskip GSK3B interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:25920809)
UniProt
Ensembl
RGD
PMID:25920809 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:124,586,087...124,609,106
Ensembl chr 6:124,586,070...124,609,100
JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:15659221 RGD:1641883 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21771788), (PMID:26095851)
(PMID:18948261)
GO_REF:0000033
RGD
GO_Central
PMID:18948261 PMID:21771788 PMID:26095851 GO_REF:0000033 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
JBrowse link
G Mapt microtubule-associated protein tau IDA RGD PMID:12420308 RGD:8158111 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Melk maternal embryonic leucine zipper kinase acts_upstream_of_or_within ISO (PMID:18948261) RGD PMID:18948261 NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937
JBrowse link
G Nox1 NADPH oxidase 1 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
MGI:3616995 (PMID:19661248)
Ensembl
RGD
PMID:19661248 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:18541534)
UniProt
Ensembl
RGD
PMID:18541534 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO (PMID:21030605) RGD PMID:21030605 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (PMID:10082581) RGD PMID:10082581 NCBI chr 8:97,038,845...97,048,080
Ensembl chr 8:97,038,840...97,047,824
JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO MGI:1857480 (PMID:15642323) RGD PMID:15642323 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO
ISS
(PMID:19604147)
GO_REF:0000024
RGD
UniProt
PMID:19604147 GO_REF:0000024 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO MGI:3043446 (PMID:15271982) RGD PMID:15271982 NCBI chr 8:61,259,415...61,347,789
Ensembl chr 8:61,259,477...61,347,789
JBrowse link
G Zfp622 zinc finger protein 622 involved_in ISO (PMID:21771788) RGD PMID:21771788 NCBI chr 2:76,479,605...76,494,405
Ensembl chr 2:76,335,609...76,493,898
JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07067600.1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 9:48,763,742...48,764,305 JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1929260 (PMID:20436477)
Ensembl
RGD
PMID:20436477 GO_REF:0000107 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
IEA
ISS
(PMID:18188704)
GO_REF:0000107
RGD
Ensembl
PMID:18188704 PMID:18188704 GO_REF:0000107, RGD:8553738 NCBI chr 1:243,024,611...243,031,749
Ensembl chr 1:243,024,614...243,031,653
JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO
IBA
(PMID:18371312)
GO_REF:0000033
RGD
GO_Central
PMID:18371312 GO_REF:0000033 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bnip3-ps3 BCL2 interacting protein 3, pseudogene 3 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr  X:41,782,256...41,782,924
Ensembl chr  X:41,782,209...41,782,898
Ensembl chr  X:41,782,209...41,782,898
JBrowse link
G Bnip3l BCL2 interacting protein 3 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803
JBrowse link
G ENSRNOG00000066967 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 8:96,464,314...96,465,381 JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO (PMID:11700312) RGD PMID:11700312 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Rhot1 ras homolog family member T1 involved_in ISO (PMID:12482879) RGD PMID:12482879 NCBI chr10:65,198,700...65,262,807
Ensembl chr10:65,170,560...65,262,804
JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISS
ISO
GO_REF:0000024
(PMID:12482879)
UniProt
RGD
PMID:12482879 GO_REF:0000024 NCBI chr10:14,858,954...14,864,751
Ensembl chr10:14,858,956...14,864,751
JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO
ISS
(PMID:31015432)
GO_REF:0000024
RGD
UniProt
PMID:31015432 GO_REF:0000024 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO MGI:1930187 (PMID:17488777) RGD PMID:17488777 NCBI chr10:69,299,029...69,392,207
Ensembl chr10:69,299,037...69,392,201
JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS
(PMID:15946935)
GO_REF:0000024
RGD
UniProt
PMID:15946935 GO_REF:0000024 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162
JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:2675387 (PMID:18436203) RGD PMID:18436203 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:20097879)
(PMID:11546872)
RGD PMID:11546872 PMID:20097879 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in ISO RNAcentral:URS000055128B_10090 (MGI:6295053|PMID:26708520) RGD PMID:26708520 MGI:6295053 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO MGI:99161 (PMID:11290297) RGD PMID:11290297 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Cdk11b cyclin-dependent kinase 11B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3043373 (PMID:15060143)
Ensembl
RGD
PMID:15060143 GO_REF:0000107 NCBI chr 5:166,212,761...166,238,883
Ensembl chr 5:166,212,829...166,238,876
JBrowse link
G Cth cystathionine gamma-lyase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:22244329)
Ensembl
RGD
PMID:22244329 GO_REF:0000107 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO MGI:1858008|MGI:2148567|MGI:98957 (PMID:15131783), (PMID:20454446) RGD PMID:15131783 PMID:20454446 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO UniProtKB:P35411 (PMID:10869418) RGD PMID:10869418 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:4888719 (PMID:21209208)
GO_Central
RGD
PMID:21209208 GO_REF:0000033 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (MGI:5780531|PMID:25590961) RGD PMID:25590961 MGI:5780531 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within ISO (PMID:15731106) RGD PMID:15731106 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Igbp1 immunoglobulin binding protein 1 acts_upstream_of_or_within ISO MGI:2448686|MGI:3056510 (PMID:15499020) RGD PMID:15499020 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049
JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within ISO MGI:4879096 (PMID:21124965) RGD PMID:21124965 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within ISO (PMID:14735464) RGD PMID:14735464 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO (PMID:10756100) RGD PMID:10756100 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO (PMID:21059917) RGD PMID:21059917 NCBI chr 1:76,861,267...76,872,691
Ensembl chr 1:76,861,924...76,872,691
JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:26780211) RGD PMID:26780211 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within ISO MGI:2678322 (PMID:12970171) RGD PMID:12970171 NCBI chr10:59,699,208...59,714,848
Ensembl chr10:59,699,585...59,714,835
JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within ISO (PMID:12019265) RGD PMID:12019265 NCBI chr 7:112,544,305...112,714,418
Ensembl chr 7:112,544,312...112,714,418
JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within ISO MGI:2682607|MGI:99702 (PMID:18436203) RGD PMID:18436203 NCBI chr19:23,978,465...23,988,933
Ensembl chr19:23,985,504...23,988,932
JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1862000 (PMID:16712836)
Ensembl
RGD
PMID:16712836 GO_REF:0000107 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO
IEA
(PMID:19429166)
GO_REF:0000107
RGD
Ensembl
PMID:19429166 GO_REF:0000107 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (PMID:20719856) RGD PMID:20719856 NCBI chr10:10,942,534...10,950,654
Ensembl chr10:10,943,001...10,950,649
JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within ISO MGI:88174 (PMID:11290297) RGD PMID:11290297 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:109284 (PMID:15148382) RGD PMID:15148382 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:15148382) RGD PMID:15148382 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA
(PMID:11096076)
GO_REF:0000107
RGD
Ensembl
PMID:11096076 GO_REF:0000107 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IMP PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA
IEA
(PMID:21075086)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:21075086 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO RNAcentral:URS0000330617_9606 (PMID:31124343) RGD PMID:31124343 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO (PMID:17200136) RGD PMID:17200136 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380
JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO MGI:88276|MGI:96571 (PMID:20454446) RGD PMID:20454446 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IDA PMID:12191471
PMID:15383280
UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS
(PMID:29507230)
GO_REF:0000024
RGD
UniProt
PMID:29507230 GO_REF:0000024 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO (PMID:16940180) RGD PMID:16940180 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO
PMID:15665855
(MGI:5616321|PMID:15665855)
RGD PMID:15665855 PMID:15665855 MGI:5616321, RGD:1558627 NCBI chr 3:77,952,589...77,993,513
Ensembl chr 3:77,952,540...77,993,456
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1341830|MGI:99682 (PMID:22240901)
Ensembl
RGD
PMID:22240901 GO_REF:0000107 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IBA
(PMID:15102845)
GO_REF:0000033
RGD
GO_Central
PMID:15102845 GO_REF:0000033 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (MGI:5495588|PMID:23453807) RGD PMID:23453807 MGI:5495588 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21857923) RGD PMID:21857923 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:5495588|PMID:23453807)
UniProtKB:P58281 (PMID:23453807)
ParkinsonsUK-UCL
Ensembl
RGD
PMID:23453807 GO_REF:0000024 GO_REF:0000107 MGI:5495588 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
GO_REF:0000107
(MGI:5613479|PMID:14652021)
RGD
Ensembl
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO MGI:2181360 (PMID:20811152) RGD PMID:20811152 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
GO_REF:0000024
(MGI:5433837|PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)
ParkinsonsUK-UCL
RGD
PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 MGI:5433837 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO (MGI:5619464|PMID:21216966) RGD PMID:21216966 MGI:5619464 NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA
(PMID:17210132)
GO_REF:0000107
RGD
Ensembl
PMID:17210132 GO_REF:0000107 NCBI chr 1:119,659,779...119,669,546
Ensembl chr 1:119,659,751...119,669,833
JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within
ISO (PMID:12459480), (PMID:17059562)
MGI:2679656 (PMID:15611074)
RGD PMID:12459480 PMID:15611074 PMID:17059562 NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within
ISO (PMID:21075086)
MGI:1913418 (PMID:22240901)
RGD PMID:21075086 PMID:22240901 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:18628206)
GO_REF:0000107
RGD
Ensembl
PMID:18628206 GO_REF:0000107 NCBI chr 5:123,587,854...123,612,886
Ensembl chr 5:123,586,781...123,612,870
JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO (MGI:3629256|PMID:16571599) RGD PMID:16571599 MGI:3629256 NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP
(PMID:19135031)
GO_REF:0000107
PMID:20625543
RGD
Ensembl
PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in ISO
IEA
(MGI:3697528|PMID:17116640)
GO_REF:0000107
RGD
Ensembl
PMID:17116640 GO_REF:0000107 MGI:3697528 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
UniProtKB:O15354 (MGI:3697528|PMID:17116640), (MGI:5495588|PMID:23453807)
GO_REF:0000107
RGD
Ensembl
PMID:17116640 PMID:23453807 GO_REF:0000107 MGI:3697528 MGI:5495588 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA
(PMID:9884026)
GO_REF:0000107
RGD
Ensembl
PMID:9884026 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241
JBrowse link
G Ar androgen receptor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21310825)
Ensembl
UniProt
RGD
PMID:21310825 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO (PMID:14765125) RGD PMID:14765125 NCBI chr 6:20,722,922...20,916,396
Ensembl chr 6:20,722,922...20,916,434
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3039210|PMID:15070745)
Ensembl
RGD
PMID:15070745 GO_REF:0000107 MGI:3039210 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:22266862), (PMID:9208847)
MGI:109324|MGI:2154952 (PMID:22675671)
RGD PMID:9208847 PMID:22266862 PMID:22675671 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cttn cortactin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1924375 (PMID:22660580)
Ensembl
RGD
PMID:22660580 GO_REF:0000107 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164
JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (PMID:15734730) RGD PMID:15734730 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (PMID:15632112) RGD PMID:15632112 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO MGI:104995 (PMID:15288121) RGD PMID:15288121 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO MGI:104990 (PMID:15288121) RGD PMID:15288121 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO (PMID:16636664) RGD PMID:16636664 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Htt huntingtin involved_in ISO
IEA
(PMID:19240112)
GO_REF:0000107
RGD
Ensembl
PMID:19240112 GO_REF:0000107 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
IDA
(PMID:16942485)
GO_REF:0000107
PMID:17023532
RGD
Ensembl
PMID:16942485 PMID:17023532 GO_REF:0000107, RGD:1600072 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:23468852) RGD PMID:23468852 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) RGD PMID:21310825 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Itgav integrin subunit alpha V involved_in ISO (PMID:10708943) RGD PMID:10708943 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Lgals3 galectin 3 involved_in ISO
IBA
IEA
(PMID:22761016)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
RGD
GO_Central
TreeGrafter
Ensembl
PMID:22761016 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lmna lamin A/C involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:21151901)
Ensembl
RGD
PMID:21151901 GO_REF:0000107 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Mir142 microRNA 142 involved_in ISO UniProtKB:P01137 (PMID:26572508) RGD PMID:26572508 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:22821565) RGD PMID:22821565 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IEA
IBA
(PMID:9560245)
GO_REF:0000118
GO_REF:0000107
GO_REF:0000033
RGD
TreeGrafter
Ensembl
GO_Central
PMID:9560245 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:5287519|PMID:21828096) RGD PMID:21828096 MGI:5287519 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within ISO (PMID:12897128) RGD PMID:12897128 NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930
JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS
(PMID:21785459)
GO_REF:0000024
RGD
ParkinsonsUK-UCL
PMID:21785459 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO (PMID:24113711)
MGI:5441750 (PMID:23950925)
RGD PMID:23950925 PMID:24113711 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857
JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (PMID:17636024) RGD PMID:17636024 NCBI chr 8:83,776,802...83,891,192
Ensembl chr 8:83,781,465...83,894,283
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:15259009) RGD PMID:15259009 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO (PMID:18309296) RGD PMID:18309296 NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO MGI:3690329 (PMID:17015619) RGD PMID:17015619 NCBI chr 5:13,161,648...13,225,560
Ensembl chr 5:13,161,648...13,225,560
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within
ISO (PMID:21310825)
(PMID:22244329)
RGD PMID:21310825 PMID:22244329 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within
ISO (PMID:21525013)
MGI:104798|MGI:109200 (PMID:22089168)
RGD PMID:21525013 PMID:22089168 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within ISO (PMID:11493700) RGD PMID:11493700 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Scg2 secretogranin II involved_in ISO
IEA
(PMID:14970115)
GO_REF:0000107
RGD
Ensembl
PMID:14970115 GO_REF:0000107 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097
JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO (PMID:21586138) RGD PMID:21586138 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA
(PMID:19767770)
GO_REF:0000033
RGD
GO_Central
PMID:19767770 GO_REF:0000033 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IMP PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA
(PMID:18625725)
GO_REF:0000107
RGD
Ensembl
PMID:18625725 GO_REF:0000107 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (MGI:3055167|PMID:11009421) RGD PMID:11009421 MGI:3055167 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) RGD PMID:11567634 MGI:2150820 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599
JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (MGI:5287519|PMID:21828096) RGD PMID:21828096 MGI:5287519 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Yap1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:95484 (PMID:17980593)
Ensembl
RGD
PMID:17980593 GO_REF:0000107 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:60,542,669...60,631,913
Ensembl chr17:60,543,077...60,631,902
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295
JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:99702 (PMID:8358790)
GO_REF:0000107
RGD
Ensembl
PMID:8358790 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2152978 (PMID:9299161)
Ensembl
RGD
PMID:9299161 GO_REF:0000107 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within ISO (PMID:18322241), (PMID:18971423) RGD PMID:18322241 PMID:18971423 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1857803 (PMID:15817220)
GO_Central
RGD
PMID:15817220 GO_REF:0000033 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518
JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976
JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:16956603) RGD PMID:16956603 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:15070677) RGD PMID:15070677 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA
(PMID:10921886)
GO_REF:0000107
RGD
Ensembl
PMID:10921886 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Gfral GDNF family receptor alpha like involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16086688)
Ensembl
RGD
PMID:16086688 GO_REF:0000107 NCBI chr 8:76,917,894...76,963,258
Ensembl chr 8:76,918,657...76,959,425
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:8950980)
Ensembl
RGD
PMID:8950980 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA
UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107
RGD
Ensembl
PMID:20551324 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:9115640)
Ensembl
RGD
PMID:9115640 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:5306563|PMID:20125124) RGD PMID:20125124 MGI:5306563 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:11050396)
Ensembl
RGD
PMID:11050396 GO_REF:0000107 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (PMID:10518215) RGD PMID:10518215 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO (PMID:12574163) RGD PMID:12574163 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084
JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:10449030) RGD PMID:10449030 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10666185), (PMID:10748004) RGD PMID:10666185 PMID:10748004 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO
IEA
(PMID:18469807)
GO_REF:0000107
RGD
Ensembl
PMID:18469807 GO_REF:0000107 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 acts_upstream_of_or_within ISO (PMID:12748172) RGD PMID:12748172 NCBI chr 4:58,989,989...59,011,925
Ensembl chr 4:58,989,987...59,011,933
JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355
JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
(PMID:23415688)
GO_REF:0000107
RGD
Ensembl
PMID:23415688 GO_REF:0000107 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within
ISO (PMID:18202225)
(PMID:26582200)
RGD PMID:18202225 PMID:26582200 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:10075978)
GO_Central
RGD
PMID:10075978 GO_REF:0000033 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Faiml Fas apoptotic inhibitory molecule like involved_in IBA
IEA
GO_REF:0000033
GO_REF:0000118
GO_Central
TreeGrafter
GO_REF:0000033 GO_REF:0000118 NCBI chr 8:99,791,849...99,810,206
Ensembl chr 8:99,791,981...99,810,228
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IEA
IBA
(PMID:10903502)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:10903502 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fgl1 fibrinogen-like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:12221075)
Ensembl
RGD
PMID:12221075 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:18846110)
UniProt
Ensembl
RGD
PMID:18846110 GO_REF:0000024 GO_REF:0000107 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hgf hepatocyte growth factor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:15314156)
Ensembl
RGD
PMID:15314156 GO_REF:0000107 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within ISO MGI:2387671 (PMID:19139395) RGD PMID:19139395 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA
(PMID:18202225)
GO_REF:0000107
RGD
Ensembl
PMID:18202225 GO_REF:0000107 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within ISO MGI:1916885 (PMID:20053891) RGD PMID:20053891 NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408
JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:12191471
PMID:15383280
UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:10442631)
(PMID:10588860)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
RGD
TreeGrafter
GO_Central
Ensembl
PMID:10442631 PMID:10588860 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2388026|MGI:95484|MGI:99255 (PMID:16365167)
Ensembl
RGD
PMID:16365167 GO_REF:0000107 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
IEA
IBA
ISS
(PMID:15069192)
GO_REF:0000118
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
TreeGrafter
GO_Central
Ensembl
UniProt
PMID:15069192 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434
JBrowse link
G Rnf34 ring finger protein 34 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:15069192)
UniProt
GO_Central
Ensembl
RGD
PMID:15069192 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:18835034)
GO_REF:0000107
RGD
Ensembl
PMID:18835034 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (MGI:4835156|PMID:9391078) RGD PMID:9391078 MGI:4835156 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISO
ISS
(PMID:21107705)
GO_REF:0000024
RGD
UniProt
PMID:21107705 GO_REF:0000024 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:12167698) RGD PMID:12167698 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 acts_upstream_of_or_within ISO (PMID:12466268) MGI
RGD
PMID:12466268 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309
JBrowse link
G Ybx3 Y box binding protein 3 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA
UniProtKB:Q99LX0 (PMID:14652021)
GO_REF:0000107
(MGI:5613479|PMID:14652021)
RGD
Ensembl
PMID:14652021 GO_REF:0000107 MGI:5613479 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (PMID:21177249), (PMID:23261939) RGD PMID:21177249 PMID:23261939 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IDA
IBA
IEA
ISO
PMID:11231630
GO_REF:0000033
GO_REF:0000107
(PMID:10037731)
GO_Central
Ensembl
RGD
PMID:10037731 PMID:11231630 GO_REF:0000033 GO_REF:0000107, RGD:10047348 NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
JBrowse link
G Kdm6a lysine demethylase 6A IMP RGD PMID:30887465 RGD:151665136 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP
PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO
GO_REF:0000107
(MGI:6444553|PMID:30496354)
Ensembl
RGD
PMID:30496354 GO_REF:0000107 MGI:6444553 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:5558956|PMID:24553947) RGD PMID:24553947 MGI:5558956 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19911006)
Ensembl
RGD
PMID:19911006 GO_REF:0000107 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IBA
IEA
(PMID:11684014)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:11684014 GO_REF:0000033 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO
IEA
IBA
(PMID:12011449)
GO_REF:0000118
GO_REF:0000033
(PMID:21567405)
RGD
TreeGrafter
GO_Central
PMID:12011449 PMID:21567405 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367
JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:9,479,532...9,493,169
Ensembl chr  X:9,479,532...9,493,168
JBrowse link
G Fignl1 fidgetin-like 1 acts_upstream_of_or_within ISO (PMID:20886204) RGD PMID:20886204 NCBI chr14:86,368,670...86,381,728
Ensembl chr14:86,368,675...86,377,455
JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3808723 (PMID:18511420) RGD PMID:18511420 NCBI chr 6:68,763,847...68,795,305
Ensembl chr 6:68,764,185...68,793,924
JBrowse link
G Gcg glucagon involved_in ISO (MGI:4453294|PMID:19915011) RGD PMID:19915011 MGI:4453294 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:1097691 (PMID:21093383) RGD PMID:21093383 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G