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ONTOLOGY REPORT - ANNOTATIONS


Term:ligand-gated ion channel signaling pathway
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Accession:GO:1990806 term browser browse the term
Definition:The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: ligand-gated ion channel signalling pathway



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AMPA selective glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plp1 proteolipid protein 1 IMP RGD PMID:16510724 RGD:30296668 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032
JBrowse link
ionotropic glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2652346 (MGI:3604036|PMID:16025111)
UniProt
RGD
PMID:16025111 GO_REF:0000024 MGI:3604036 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:3696954 (MGI:3696486|PMID:17234593) RGD PMID:17234593 MGI:3696486 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in IDA PMID:12223541 UniProt PMID:12223541 RGD:8554161 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 involved_in IDA PMID:12223541 UniProt PMID:12223541 RGD:8554161 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO MGI:1933976 (MGI:3653554|PMID:16483786) RGD PMID:16483786 MGI:3653554 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cpeb4 cytoplasmic polyadenylation element binding protein 4 involved_in IDA PMID:20937770 UniProt PMID:20937770 RGD:8553637 NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase TAS RGD PMID:12736333 RGD:1358550 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 involved_in IEA
ISS
ISO
GO_REF:0000108
GO_REF:0000024
(PMID:20614889)
GOC
UniProt
RGD
PMID:20614889 GO_REF:0000024 GO_REF:0000108 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Grid1 glutamate ionotropic receptor delta type subunit 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr16:10,138,564...10,885,803
Ensembl chr16:10,138,925...10,885,808
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 acts_upstream_of_or_within
involved_in
IDA
ISO
IEA
MGI:95815 (MGI:3575241|PMID:11985817)
GO_REF:0000108
RGD
GOC
PMID:11985817 PMID:17395219 GO_REF:0000108 MGI:3575241, RGD:1642466 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000108
(MGI:2387276|PMID:12223554)
GOC
RGD
PMID:12223554 GO_REF:0000108 MGI:2387276 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in
acts_upstream_of_or_within
IDA
IC
IEA
ISO
IBA
GO_REF:0000114
GO_REF:0000108
PMID:19793963
(MGI:3604036|PMID:16025111)
PMID:21873635
(PMID:28228639)
ComplexPortal
GOC
RGD
PMID:16025111 PMID:28228639 PMID:16477151 PMID:19793963 PMID:21873635 GO_REF:0000108 GO_REF:0000114 MGI:3604036, RGD:1642190, RGD:150521643, RGD:13792537 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A involved_in IDA
IC
IEA
GO_REF:0000114
PMID:19793963
GO_REF:0000108
ComplexPortal
GOC
RGD
PMID:16477151 PMID:19793963 GO_REF:0000108 GO_REF:0000114, RGD:1642190, RGD:150521643 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in IDA
IEA
IC
GO_REF:0000108
GO_REF:0000114
PMID:19793963
GOC
ComplexPortal
RGD
PMID:16477151 PMID:19793963 GO_REF:0000108 GO_REF:0000114, RGD:1642190, RGD:150521643 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C involved_in IEA
IDA
GO_REF:0000108
PMID:19793963
GOC PMID:19793963 GO_REF:0000108, RGD:150521643 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D involved_in
acts_upstream_of_or_within
IDA
ISO
PMID:19793963
MGI:1928298 (MGI:2667489|PMID:12832518)
RGD PMID:12832518 PMID:19793963 MGI:2667489, RGD:150521643 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A involved_in IDA
IEA
IBA
GO_REF:0000108
PMID:21873635
GOC
RGD
PMID:16477151 PMID:21873635 GO_REF:0000108, RGD:1642190, RGD:13792537 NCBI chr 5:64,006,847...64,206,408
Ensembl chr 5:64,009,980...64,206,085
JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B involved_in IDA
IEA
IBA
GO_REF:0000108
PMID:21873635
GOC
RGD
PMID:11823786 PMID:21873635 GO_REF:0000108, RGD:632842, RGD:13792537 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP PMID:15814199 Alzheimers_University_of_Toronto PMID:15814199 RGD:8655534 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
NMDA selective glutamate receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha involved_in IMP PMID:20670832 SynGO PMID:20670832 RGD:12050125 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in IMP PMID:15987933 SynGO PMID:15987933 RGD:12050132 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Kalrn kalirin, RhoGEF kinase involved_in IMP PMID:18031682 SynGO PMID:18031682 RGD:12050112 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in IMP PMID:15721239 SynGO PMID:15721239 RGD:12050147 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20094
    signaling 7674
      signal transduction 7105
        ligand-gated ion channel signaling pathway 29
          ionotropic glutamate receptor signaling pathway + 29
          serotonin-gated cation-selective signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20094
    biological regulation 13926
      regulation of biological process 13157
        regulation of cellular process 12435
          signal transduction 7105
            ligand-gated ion channel signaling pathway 29
              ionotropic glutamate receptor signaling pathway + 29
              serotonin-gated cation-selective signaling pathway 0
paths to the root