Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:CD40 signaling pathway
go back to main search page
Accession:GO:0023035 term browser browse the term
Definition:The series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: CD40 signalling pathway


show annotations for term's descendants           Sort by:
CD40 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 molecule involved_in ISO
IEA 		MGI:2143599 (PMID:18624351)
(PMID:15708970), (PMID:21410936), (PMID:31331973), (PMID:8910514)
GO_REF:0000107 		RGD
Ensembl		 PMID:8910514 PMID:15708970 PMID:18624351 PMID:21410936 PMID:31331973 GO_REF:0000107 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand involved_in IEA
ISO 		GO_REF:0000107
(PMID:1280226), (PMID:31331973) 		Ensembl
RGD		 PMID:1280226 PMID:31331973 GO_REF:0000107 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Itga5 integrin subunit alpha 5 involved_in ISO
IEA 		(PMID:31331973)
GO_REF:0000107 		RGD
Ensembl		 PMID:31331973 GO_REF:0000107 NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:31331973) RGD PMID:31331973 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Rnf31 ring finger protein 31 involved_in ISO
IEA 		(PMID:20614026)
GO_REF:0000107 		RGD
Ensembl		 PMID:20614026 GO_REF:0000107 NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO
IEA 		(PMID:16633345)
GO_REF:0000107 		RGD
Ensembl		 PMID:16633345 GO_REF:0000107 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO
IEA 		(PMID:15708970)
GO_REF:0000107 		RGD
Ensembl		 PMID:15708970 GO_REF:0000107 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 involved_in ISO MGI:88336 (PMID:18624351) RGD PMID:18624351 NCBI chr20:44,565,992...44,609,240
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf5 TNF receptor-associated factor 5 involved_in ISO
IEA 		(PMID:15708970)
GO_REF:0000107 		RGD
Ensembl		 PMID:15708970 GO_REF:0000107 NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in ISO (PMID:8910514) RGD PMID:8910514 NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
negative regulation of CD40 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO
IEA 		(PMID:16317102)
GO_REF:0000107 		RGD
Ensembl		 PMID:16317102 GO_REF:0000107 NCBI chr13:86,802,708...86,837,890
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA 		(PMID:12885753)
GO_REF:0000107 		RGD
Ensembl		 PMID:12885753 GO_REF:0000107 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
positive regulation of CD40 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IEA 		(PMID:11602640)
GO_REF:0000107 		RGD
Ensembl		 PMID:11602640 GO_REF:0000107 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of CD40 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fanca FA complementation group A acts_upstream_of_or_within ISO
IEA 		MGI:2674094 (PMID:24501220)
GO_REF:0000107 		RGD
Ensembl		 PMID:24501220 GO_REF:0000107 NCBI chr19:68,210,562...68,271,080
Ensembl chr19:51,304,021...51,362,527 		JBrowse link
G Fancd2 FA complementation group D2 acts_upstream_of_or_within ISO
IEA 		MGI:2673422 (PMID:24501220)
GO_REF:0000107 		RGD
Ensembl		 PMID:24501220 GO_REF:0000107 NCBI chr 4:148,234,633...148,299,035
Ensembl chr 4:146,679,179...146,743,412 		JBrowse link
G Sharpin SHANK-associated RH domain interactor involved_in ISO
ISS 		(PMID:21455173)
GO_REF:0000024 		RGD
UniProt		 PMID:21455173 GO_REF:0000024 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955 		JBrowse link
G Tnfsf18 TNF superfamily member 18 NOT|involved_in ISO (PMID:24107315) RGD PMID:24107315 NCBI chr13:76,366,790...76,440,673
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          CD40 signaling pathway 17
            negative regulation of CD40 signaling pathway 2
            positive regulation of CD40 signaling pathway 1
            regulation of CD40 signaling pathway + 7
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        signaling 7874
          signal transduction 7313
            cell surface receptor signaling pathway 2915
              CD40 signaling pathway 17
                negative regulation of CD40 signaling pathway 2
                positive regulation of CD40 signaling pathway 1
                regulation of CD40 signaling pathway + 7
paths to the root