Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:reelin-mediated signaling pathway
go back to main search page
Accession:GO:0038026 term browser browse the term
Definition:The series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: reeler-mediated signaling pathway;   reelin-mediated signal transduction pathway;   reelin-mediated signalling pathway


show annotations for term's descendants           Sort by:
reelin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crk CRK proto-oncogene, adaptor protein acts_upstream_of_or_within ISO
IEA 		MGI:104686 (PMID:18477607), (PMID:19074029)
GO_REF:0000107 		RGD
Ensembl		 PMID:18477607 PMID:19074029 GO_REF:0000107 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:1931805|MGI:88508 (PMID:17394141), (PMID:18477607), (PMID:19074029) RGD PMID:17394141 PMID:18477607 PMID:19074029 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Cul5 cullin 5 acts_upstream_of_negative_effect ISS
ISO 		GO_REF:0000024
(PMID:17974915), (PMID:24210661) 		UniProt
RGD		 PMID:17974915 PMID:24210661 GO_REF:0000024 NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:54,016,006...54,066,666 		JBrowse link
G Dab1 DAB adaptor protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12526739), (PMID:9338784), (PMID:9338785) 		Ensembl
RGD		 PMID:9338784 PMID:9338785 PMID:12526739 GO_REF:0000107 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552 		JBrowse link
G Fkrp fukutin related protein acts_upstream_of_or_within ISO MGI:4835411 (PMID:28039900) RGD PMID:28039900 NCBI chr 1:77,479,641...77,486,954
Ensembl chr 1:77,476,084...77,486,992 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:12526739) 		UniProt
Ensembl
RGD		 PMID:12526739 GO_REF:0000024 GO_REF:0000107 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Lrp8 LDL receptor related protein 8 involved_in ISO
IEA 		(PMID:10571241), (PMID:18778775), (PMID:21852430)
GO_REF:0000107 		RGD
Ensembl		 PMID:10571241 PMID:18778775 PMID:21852430 GO_REF:0000107 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:17330141)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:17330141 GO_REF:0000024 GO_REF:0000107 NCBI chr10:60,031,441...60,090,259
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Reln reelin involved_in ISS
ISO 		GO_REF:0000024
(PMID:10571240), (PMID:10571241), (PMID:10880573), (PMID:21852430) 		UniProt
RGD		 PMID:10571240 PMID:10571241 PMID:10880573 PMID:21852430 GO_REF:0000024 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_negative_effect ISO (PMID:24210661) RGD PMID:24210661 NCBI chr 8:105,918,395...105,927,643
Ensembl chr 8:97,038,840...97,047,824 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO
IEA 		(PMID:29581031)
GO_REF:0000107 		RGD
Ensembl		 PMID:29581031 GO_REF:0000107 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Vldlr very low density lipoprotein receptor involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q924X6 (PMID:10571241), (PMID:18778775) 		Ensembl
RGD		 PMID:10571241 PMID:18778775 GO_REF:0000107 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    cellular process 19534
      signal transduction 7313
        cell surface receptor signaling pathway 2915
          reelin-mediated signaling pathway 12
Path 2
Term Annotations click to browse term
  biological_process 20543
    biological regulation 13835
      regulation of biological process 13398
        signaling 7874
          signal transduction 7313
            cell surface receptor signaling pathway 2915
              reelin-mediated signaling pathway 12
paths to the root