Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ptpdc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTPDC1 mRNA | CTD | PMID:19465110 | Ptpdc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of PTPDC1 mRNA | CTD | PMID:33387578 | Ptpdc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTPDC1 mRNA | CTD | PMID:22574217 | Ptpdc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PTPDC1 mRNA | CTD | PMID:21570461 | Ptpdc1 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Decitabine affects the expression of PTPDC1 mRNA | CTD | PMID:23300844 | Ptpdc1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PTPDC1 mRNA | CTD | PMID:24780913 | Ptpdc1 | Rat | aflatoxin B1 | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PTPDC1 mRNA | CTD | PMID:19770486 | Ptpdc1 | Rat | all-trans-retinoic acid | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of PTPDC1 mRNA | CTD | PMID:33167477 | Ptpdc1 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of PTPDC1 mRNA | CTD | PMID:30779732 | Ptpdc1 | Rat | antirheumatic drug | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PTPDC1 mRNA | CTD | PMID:24449571 | Ptpdc1 | Rat | arsenous acid | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of PTPDC1 mRNA | CTD | PMID:20458559 | Ptpdc1 | Rat | avobenzone | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | avobenzone results in increased expression of PTPDC1 mRNA | CTD | PMID:31016361 | Ptpdc1 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | PTPDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of PTPDC1 gene | CTD | PMID:25435355 | Ptpdc1 | Rat | benzo[a]pyrene | increases methylation | ISO | PTPDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PTPDC1 promoter | CTD | PMID:27901495 | Ptpdc1 | Rat | benzo[a]pyrene | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of PTPDC1 mRNA | CTD | PMID:30453624 | Ptpdc1 | Rat | benzo[a]pyrene | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of PTPDC1 mRNA | CTD | PMID:19770486 and PMID:22228805 | Ptpdc1 | Rat | benzo[a]pyrene | multiple interactions | ISO | Ptpdc1 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of PTPDC1 mRNA] | CTD | PMID:22228805 | Ptpdc1 | Rat | benzo[b]fluoranthene | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of PTPDC1 mRNA | CTD | PMID:26377693 | Ptpdc1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PTPDC1 mRNA | CTD | PMID:25181051 | Ptpdc1 | Rat | bisphenol A | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PTPDC1 gene | CTD | PMID:31601247 | Ptpdc1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PTPDC1 gene | CTD | PMID:28505145 | Ptpdc1 | Rat | caffeine | decreases phosphorylation | ISO | PTPDC1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of PTPDC1 protein | CTD | PMID:35688186 | Ptpdc1 | Rat | carbon nanotube | decreases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Ptpdc1 | Rat | CGP 52608 | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PTPDC1 gene] | CTD | PMID:28238834 | Ptpdc1 | Rat | cisplatin | affects expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of PTPDC1 mRNA | CTD | PMID:23300844 | Ptpdc1 | Rat | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of PTPDC1 protein | CTD | PMID:17321087 | Ptpdc1 | Rat | copper atom | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PTPDC1 mRNA | CTD | PMID:20971185 | Ptpdc1 | Rat | copper(0) | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of PTPDC1 mRNA | CTD | PMID:20971185 | Ptpdc1 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of PTPDC1 mRNA | CTD | PMID:26577399 | Ptpdc1 | Rat | cyclosporin A | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of PTPDC1 mRNA | CTD | PMID:20106945 more ... | Ptpdc1 | Rat | diarsenic trioxide | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of PTPDC1 mRNA | CTD | PMID:20458559 | Ptpdc1 | Rat | dorsomorphin | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTPDC1 mRNA | CTD | PMID:27188386 | Ptpdc1 | Rat | doxorubicin | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PTPDC1 mRNA | CTD | PMID:29803840 | Ptpdc1 | Rat | ethanol | affects expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Ethanol affects the expression of PTPDC1 mRNA | CTD | PMID:30319688 | Ptpdc1 | Rat | folic acid | decreases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PTPDC1 mRNA | CTD | PMID:25629700 | Ptpdc1 | Rat | FR900359 | decreases phosphorylation | ISO | PTPDC1 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of PTPDC1 protein | CTD | PMID:37730182 | Ptpdc1 | Rat | fulvestrant | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of PTPDC1 gene | CTD | PMID:31601247 | Ptpdc1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PTPDC1 mRNA | CTD | PMID:33387578 | Ptpdc1 | Rat | glyphosate | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | Glyphosate results in increased expression of PTPDC1 mRNA | CTD | PMID:35897073 | Ptpdc1 | Rat | leflunomide | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | leflunomide results in increased expression of PTPDC1 mRNA | CTD | PMID:28988120 | Ptpdc1 | Rat | Monobutylphthalate | decreases expression | EXP | | 6480464 | monobutyl phthalate results in decreased expression of PTPDC1 mRNA | CTD | PMID:29162477 | Ptpdc1 | Rat | paracetamol | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of PTPDC1 mRNA | CTD | PMID:22230336 | Ptpdc1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PTPDC1 mRNA | CTD | PMID:33387578 | Ptpdc1 | Rat | perfluorooctanoic acid | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of PTPDC1 mRNA | CTD | PMID:36326898 | Ptpdc1 | Rat | phenylmercury acetate | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of PTPDC1 mRNA | CTD | PMID:26272509 | Ptpdc1 | Rat | phenylmercury acetate | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTPDC1 mRNA | CTD | PMID:27188386 | Ptpdc1 | Rat | pirinixic acid | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PTPDC1 mRNA | CTD | PMID:20813756 | Ptpdc1 | Rat | SB 431542 | multiple interactions | ISO | PTPDC1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTPDC1 mRNA | CTD | PMID:27188386 | Ptpdc1 | Rat | sodium arsenite | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of PTPDC1 mRNA | CTD | PMID:38568856 | Ptpdc1 | Rat | sodium arsenite | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of PTPDC1 mRNA | CTD | PMID:34032870 | Ptpdc1 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of PTPDC1 mRNA | CTD | PMID:31150632 | Ptpdc1 | Rat | thapsigargin | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of PTPDC1 mRNA | CTD | PMID:22378314 | Ptpdc1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of PTPDC1 mRNA | CTD | PMID:33387578 | Ptpdc1 | Rat | trichostatin A | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PTPDC1 mRNA | CTD | PMID:24935251 | Ptpdc1 | Rat | triphenyl phosphate | affects expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of PTPDC1 mRNA | CTD | PMID:37042841 | Ptpdc1 | Rat | Triptolide | increases expression | ISO | Ptpdc1 (Mus musculus) | 6480464 | triptolide results in increased expression of PTPDC1 mRNA | CTD | PMID:32835833 | Ptpdc1 | Rat | tunicamycin | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of PTPDC1 mRNA | CTD | PMID:22378314 | Ptpdc1 | Rat | valproic acid | decreases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PTPDC1 mRNA | CTD | PMID:23179753 | Ptpdc1 | Rat | valproic acid | affects expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PTPDC1 mRNA | CTD | PMID:25979313 | Ptpdc1 | Rat | valproic acid | increases expression | ISO | PTPDC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PTPDC1 mRNA | CTD | PMID:24935251 and PMID:29154799 | Ptpdc1 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of PTPDC1 mRNA | CTD | PMID:23869203 | |