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Gene: Mgrn1 (mahogunin ring finger 1) Rattus norvegicus
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Symbol: Mgrn1
Name: mahogunin ring finger 1
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in cellular protein modification process; endosome to lysosome transport; and negative regulation of signal transduction. Predicted to localize to the early endosome; nucleus; and plasma membrane. Orthologous to human MGRN1 (mahogunin ring finger 1); PARTICIPATES IN melanocortin system pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH bisphenol A; furan; vinclozolin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase MGRN1; LOC302938; mahoganoid; mahogunin ring finger 1, E3 ubiquitin protein ligase; mahogunin RING finger protein 1; mahogunin, ring finger 1; probable E3 ubiquitin-protein ligase MGRN1; RGD1311862; RING-type E3 ubiquitin transferase MGRN1; similar to mahogunin, ring finger 1
Orthologs:
Homo sapiens (human) : MGRN1 (mahogunin ring finger 1)  HGNC  Alliance
Mus musculus (house mouse) : Mgrn1 (mahogunin, ring finger 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mgrn1 (mahogunin ring finger 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MGRN1 (mahogunin ring finger 1)
Canis lupus familiaris (dog) : MGRN1 (mahogunin ring finger 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mgrn1 (mahogunin ring finger 1)
Sus scrofa (pig) : MGRN1 (mahogunin ring finger 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01010,832,573 - 10,881,999 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0109,599,503 - 9,648,909 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,756,804 - 10,805,883 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11010,756,804 - 10,805,883 (-)NCBI
Celera109,604,036 - 9,652,494 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mgrn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311862
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.