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Gene: Gli2 (GLI family zinc finger 2) Rattus norvegicus
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Symbol: Gli2
Name: GLI family zinc finger 2
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; promoter-specific chromatin binding activity; and zinc ion binding activity. Involved in prostate gland development and response to mechanical stimulus. Predicted to localize to several cellular components, including the axoneme; ciliary tip; and nuclear lumen. Biomarker of esophageal atresia/tracheoesophageal fistula. Human ortholog(s) of this gene implicated in Culler-Jones syndrome; holoprosencephaly 9; and spina bifida. Orthologous to human GLI2 (GLI family zinc finger 2); PARTICIPATES IN Hedgehog signaling pathway; basal cell carcinoma pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GLI-Kruppel family member GLI2; LOC304729; zinc finger protein GLI2
Orthologs:
Homo sapiens (human) : GLI2 (GLI family zinc finger 2)  HGNC  Alliance
Mus musculus (house mouse) : Gli2 (GLI-Kruppel family member GLI2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gli2 (GLI family zinc finger 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GLI2 (GLI family zinc finger 2)
Canis lupus familiaris (dog) : GLI2 (GLI family zinc finger 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gli2 (GLI family zinc finger 2)
Sus scrofa (pig) : GLI2 (GLI family zinc finger 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01334,829,021 - 35,049,172 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1334,829,139 - 35,048,444 (-)Ensembl
Rnor_5.01339,955,094 - 40,170,750 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41331,551,089 - 31,607,264 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11331,555,563 - 31,574,381 (-)NCBI
Celera1329,844,054 - 29,900,050 (-)NCBICelera
Cytogenetic Map13q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gli2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309270
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.