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Term:
Parent Terms Term With Siblings Child Terms
(2R,3S,2'R)-nadolol +   
(R)-nicardipine +   
(S)-nicardipine +   
(S)-timolol (anhydrous) +   
(S)-timolol hemihydrate 
(S)-timolol maleate 
2-hydroxyoleic acid 
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine 
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  
3-fluoro-6a,7,8,9,10,11-hexahydro-6H-azepino[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide 
4-hydroxychalcone  
6-chloro-1,1-dioxo-3-[(prop-2-enylthio)methyl]-3,4-dihydro-2H-1$l^\{6\},2,4-benzothiadiazine-7-sulfonamide 
6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^\{6\},2,4-benzothiadiazine-7-sulfonamide 
6-O-galloyl-beta-D-glucose 
7-chloro-3-methyl-3,4-dihydro-2H-1$l^\{6\},2,4-benzothiadiazine 1,1-dioxide 
acebutolol  
acebutolol hydrochloride 
acetazolamide +   
ACT-132577 +   
ajmalicine  
alfuzosin +   
aliskiren +   
aliskiren fumarate 
alpha-methyl-L-dopa +   
alpha-methyl-L-dopa ethyl ester 
alpha-methyl-L-tyrosine 
alprenolol +   
amiloride +   
amiloride hydrochloride +  
amiloride hydrochloride dihydrate 
amlodipine +   
amlodipine benzenesulfonate +  
angiotensin (1-9) 
angiotensin (1-9) dizwitterion 
apelin-13 
aquaretic +   
atenolol +   
auraptene  
azilsartan +   
azilsartan kamedoxomil 
azilsartan medoxomil 
BAY 41-2272 
bemetizide 
bendroflumethiazide +   
bentazone  
benzthiazide 
Benzylhydrochlorothiazide 
bepridil +   
beraprost  
beraprost sodium 
betaxolol +   
betaxolol hydrochloride +  
bethanidine +  
bethanidine sulfate 
bevantolol +   
bevantolol hydrochloride +  
bexagliflozin  
bimatoprost 
bisoprolol +   
bopindolol  
bosentan +   
bretylium +   
bretylium tosylate  
brimonidine +   
bumetanide  
butizide 
Byvalson 
caffeine +   
camostat  
camostat mesylate 
candesartan  
captopril +   
carmoxirole  
carmoxirole hydrochloride 
carteolol  
carteolol hydrochloride 
carvedilol  
cassaine 
chlormerodrin +  
chlorothiazide 
cilazapril +   
cilazapril monohydrate  
cilnidipine  
cinaciguat  
cleistanthin A 
cleistanthin B +  
clonidine +   
colforsin daropate 
colforsin daropate hydrochloride  
corilagin  
cyclothiazide  
debrisoquin +   
diazoxide  
diltiazem  
diltiazem hydrochloride 
dorzolamide +   
dorzolamide hydrochloride  
doxazosin +   
droxidopa 
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor +   
efonidipine 
enalapril +   
enalapril maleate 
enalaprilat (anhydrous) +   
enalaprilat dihydrate  
enrasentan  
epitizide 
eplerenone  
eprosartan +   
eprosartan methanesulfonate 
Ethiazide 
ethoxzolamide  
fasudil  
fasudil hydrochloride +  
fasudil hydrochloride hydrate 
felodipine  
fenoldopam  
flumethiazide 
fluprostenol +   
forasartan 
forskolin +   
fosinopril  
fosinopril sodium 
fosinoprilat +   
G-1 
grayanotoxin I 
GSK2181236A  
guanadrel 
guanadrel sulfate 
guanethidine +   
guanethidine monosulfate +  
guanethidine sulfate 
HU-308  
hydralazine +   
hydralazine hydrochloride 
hydrochlorothiazide  
hydroflumethiazide 
imidapril +   
imidaprilat  
indanomycin 
indapamide  
irbesartan  
isoamyl nitrite 
isopropyl unoprostone 
kaempferide +   
ketanserin  
ketanserin tartrate 
labetalol  
latanoprost  
latanoprost free acid +   
lisinopril dihydrate  
lofexidine 
loop diuretic +   
losartan +   
macitentan  
mebutizide 
Methyclothiazide 
metipranolol  
metipranolol hydrochloride 
metolazone  
metoprolol  
minoxidil  
morin  
nadolol  
nebivolol  
nebivolol hydrochloride +  
nelociguat 
nerolidol +   
nicardipine  
nimodipine  
nisoldipine  
nitrendipine  
norverapamil  
oleuropein +   
olmesartan  
osmotic diuretic +   
palmitoyl ethanolamide  
pentamethonium +  
pentamethonium bromide 
pentolinium tartrate  
perindopril  
perindopril arginine +  
perindopril erbumine 
perindoprilat 
phthalylsulfathiazole 
pindolol +   
Polythiazide 
potassium citrate (anhydrous) +   
potassium citrate monohydrate  
praliciguat 
pratosartan 
prazosin +   
Prestalia 
propranolol +   
quinapril 
quinapril hydrochloride  
quinaprilat  
quinethazone 
remikiren 
rescinnamine  
reserpine  
riociguat  
rottlerin  
scoparone  
sodium nitrite  
solasodine +   
sotagliflozin 
sparsentan 
spirapril  
spiraprilat +   
spironolactone  
sulfabenzamide 
sulfadiazine  
sulfadimethoxine  
sulfaguanidine 
sulfamazone 
sulfamerazine  
sulfamethazine +   
sulfamethizole  
sulfamethopyrazine 
sulfamethoxazole +   
sulfamethoxydiazine 
sulfamethoxypyridazine 
sulfametrole 
sulfamoxole  
sulfanilamide +   
sulfaperin 
sulfaphenazole  
sulfapyridine  
sulfathiazole +   
sulfathiourea 
sulfisomidine  
sulfisoxazole +   
teclothiazide 
telmisartan  
terazosin +   
tienilic acid  
tolazoline  
torasemide +   
trandolapril  
trandolaprilat +   
travoprost 
treprostinil +   
triamterene  
trichlormethiazide  
A benzothiadiazine, hydrogenated at positions 2, 3 and 4 and substituted with an aminosulfonyl group at C-7, a chloro substituent at C-6 and a dichloromethyl group at C-3 and with S-1 as an S,S-dioxide. A sulfonamide antibiotic, it is used as a diuretic to treat oedema (including that associated with heart failure) and hypertension.
trimethaphan +   
trimethaphan camsylate 
trimethoprim +   
U50488  
U69593  
unoprostone +  
valsartan +   
verapamil  
vericiguat 
vincamine  
visnagin 
xyloketal B 
zibotentan 
zolasartan 

Synonyms
Exact Synonyms: 6-chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Related Synonyms: Formula=C8H8Cl3N3O4S2 ;   InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16) ;   InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N ;   SMILES=C12=C(NC(C(Cl)Cl)NS1(=O)=O)C=C(Cl)C(=C2)S(N)(=O)=O ;   hydrotrichlorothiazide ;   trichlormethiazidum ;   triclormetiazida
Xrefs: CAS:133-67-5 ;   DrugBank:DB01021 ;   Drug_Central:2733 ;   KEGG:C07767 ;   KEGG:D00658 ;   LINCS:LSM-4383
Xref Mesh: MESH:D014237
Xrefs: PMID:21605415 ;   PMID:24678944 ;   PMID:25692026 ;   PMID:25938807 ;   PMID:28089902 ;   PMID:28166217 ;   PMID:29438107 ;   Wikipedia:Trichlormethiazide

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