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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethoxzolamide
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Accession:CHEBI:101096 term browser browse the term
Definition:A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
Synonyms:exact_synonym: 6-ethoxy-1,3-benzothiazole-2-sulfonamide
 related_synonym: 6-Ethoxy-benzothiazole-2-sulfonic acid amide;   6-ethoxy-2-benzothiazolesulfonamide;   6-ethoxybenzothiazole-2-sulfonamide;   Formula=C9H10N2O3S2;   InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13);   InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N;   SMILES=CCOc1ccc2nc(sc2c1)S(N)(=O)=O;   ethoxazolamide;   ethoxyzolamide
 xref: CAS:452-35-7;   DrugBank:DB00311;   Drug_Central:1089;   KEGG:D02441;   LINCS:LSM-18787
 xref_mesh: MESH:D005016
 xref: PMID:10411484;   PMID:11087579;   PMID:11123998;   PMID:11906288;   PMID:12039560;   PMID:12617903;   PMID:12617904;   PMID:12643899;   PMID:12747790;   PMID:12747791;   PMID:14611846;   PMID:14640555;   PMID:14684333;   PMID:14971907;   PMID:15081039;   PMID:15139757;   PMID:15149691;   PMID:15454239;   PMID:15456265;   PMID:15501039;   PMID:15546717;   PMID:15603956;   PMID:15664816;   PMID:15686894;   PMID:15686895;   PMID:15686931;   PMID:15771455;   PMID:15837316;   PMID:15837325;   PMID:15905091;   PMID:15908201;   PMID:15908204;   PMID:16033263;   PMID:16039848;   PMID:16039853;   PMID:16165351;   PMID:16168653;   PMID:16302824;   PMID:16459077;   PMID:16539401;   PMID:16809036;   PMID:16942027;   PMID:17064072;   PMID:17125255;   PMID:17157501;   PMID:17228881;   PMID:17251018;   PMID:17276072;   PMID:17343373;   PMID:17475500;   PMID:17482815;   PMID:17540563;   PMID:17588751;   PMID:17646100;   PMID:17681760;   PMID:17826101;   PMID:18042384;   PMID:18242985;   PMID:18307288;   PMID:18359629;   PMID:18374572;   PMID:18513964;   PMID:2585443;   PMID:2810337;   PMID:6737424;   Patent:GB795174;   Patent:US2868800;   Wikipedia:Ethoxzolamide



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ethoxzolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca3 carbonic anhydrase 3 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Car1 carbonic anhydrase 1 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        pharmaceutical 19356
          drug 19356
            diuretic 1136
              ethoxzolamide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      chalcogen 19450
                        oxygen atom 19423
                          oxygen molecular entity 19423
                            hydroxides 19158
                              oxoacid 18472
                                chalcogen oxoacid 11498
                                  sulfur oxoacid 11106
                                    sulfonic acid 7371
                                      sulfonic acid derivative 7371
                                        sulfonamide 3196
                                          ethoxzolamide 3
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