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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethoxzolamide
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Accession:CHEBI:101096 term browser browse the term
Definition:A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.
Synonyms:exact_synonym: 6-ethoxy-1,3-benzothiazole-2-sulfonamide
 related_synonym: 6-Ethoxy-benzothiazole-2-sulfonic acid amide;   6-ethoxy-2-benzothiazolesulfonamide;   6-ethoxybenzothiazole-2-sulfonamide;   Formula=C9H10N2O3S2;   InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13);   InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N;   SMILES=CCOc1ccc2nc(sc2c1)S(N)(=O)=O;   ethoxazolamide;   ethoxyzolamide
 xref: CAS:452-35-7;   DrugBank:DB00311;   Drug_Central:1089;   KEGG:D02441;   LINCS:LSM-18787
 xref_mesh: MESH:D005016
 xref: PMID:10411484;   PMID:11087579;   PMID:11123998;   PMID:11906288;   PMID:12039560;   PMID:12617903;   PMID:12617904;   PMID:12643899;   PMID:12747790;   PMID:12747791;   PMID:14611846;   PMID:14640555;   PMID:14684333;   PMID:14971907;   PMID:15081039;   PMID:15139757;   PMID:15149691;   PMID:15454239;   PMID:15456265;   PMID:15501039;   PMID:15546717;   PMID:15603956;   PMID:15664816;   PMID:15686894;   PMID:15686895;   PMID:15686931;   PMID:15771455;   PMID:15837316;   PMID:15837325;   PMID:15905091;   PMID:15908201;   PMID:15908204;   PMID:16033263;   PMID:16039848;   PMID:16039853;   PMID:16165351;   PMID:16168653;   PMID:16302824;   PMID:16459077;   PMID:16539401;   PMID:16809036;   PMID:16942027;   PMID:17064072;   PMID:17125255;   PMID:17157501;   PMID:17228881;   PMID:17251018;   PMID:17276072;   PMID:17343373;   PMID:17475500;   PMID:17482815;   PMID:17540563;   PMID:17588751;   PMID:17646100;   PMID:17681760;   PMID:17826101;   PMID:18042384;   PMID:18242985;   PMID:18307288;   PMID:18359629;   PMID:18374572;   PMID:18513964;   PMID:2585443;   PMID:2810337;   PMID:6737424;   Patent:GB795174;   Patent:US2868800;   Wikipedia:Ethoxzolamide


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ethoxzolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ca3 carbonic anhydrase 3 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Car1 carbonic anhydrase 1 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA1 protein CTD PMID:17826101 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Ethoxzolamide binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      application 19426
        pharmaceutical 19301
          drug 19301
            diuretic 1122
              ethoxzolamide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      chalcogen 19399
                        oxygen atom 19361
                          oxygen molecular entity 19361
                            hydroxides 19107
                              oxoacid 18241
                                chalcogen oxoacid 11491
                                  sulfur oxoacid 11095
                                    sulfonic acid 7340
                                      sulfonic acid derivative 7340
                                        sulfonamide 3174
                                          ethoxzolamide 3
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