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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfisomidine
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Accession:CHEBI:32166 term browser browse the term
Definition:A sulfonamide consisting of pyrimidine having methyl substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.
Synonyms:exact_synonym: 4-amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide
 related_synonym: (p-Aminobenzolsulfonyl)-4-amino-2,6-dimethylpyrimidin;   (p-Aminobenzolsulfonyl)-4-amino-2,6-dimethylpyrimidine;   2,4-Dimethyl-6-sulfanilamidopyrimidine;   4-Sulfa-2,6-dimethylpyrimidine;   4-Sulfanilamido-2,6-dimethylpyrimidine;   6-(4-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine;   6-(p-Aminobenzenesulfonamido)-2,4-dimethylpyrimidine;   6-(p-Aminobenzenesulfonyl)amino-2,4-dimethylpyrimidine;   Formula=C12H14N4O2S;   InChI=1S/C12H14N4O2S/c1-8-7-12(15-9(2)14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16);   InChIKey=YZMCKZRAOLZXAZ-UHFFFAOYSA-N;   N(1)-(2,6-Dimethyl-4-pyrimidinyl)sulfanilamide;   SMILES=Cc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1;   Sulfaisodimidine;   Sulfasomidine;   Sulphasomidine;   solfisomidina;   sulfaisodimidinum
 xref: Beilstein:261305;   CAS:515-64-0;   Drug_Central:2526;   KEGG:D01526
 xref_mesh: MESH:D013443
 xref: PMID:11431418;   PMID:13316533;   PMID:24727175;   PMID:621636;   PMID:6483571;   PMID:7051761;   Patent:FR886009;   Patent:US2351333;   Patent:US2386852;   Patent:US2429184



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sulfisomidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity EXP Sulfisomidine decreases activity of purified Hmbs protein RGD PMID:6893114 RGD:26923963 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Pon1 paraoxonase 1 decreases activity ISO Sulfisomidine results in decreased activity of PON1 protein CTD PMID:28665493 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        antimicrobial agent 17818
          sulfonamide antibiotic 256
            sulfisomidine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    main group molecular entity 19960
                      s-block molecular entity 19784
                        hydrogen molecular entity 19777
                          hydrides 19115
                            inorganic hydride 17901
                              pnictogen hydride 17884
                                nitrogen hydride 17773
                                  azane 17503
                                    ammonia 17521
                                      organic amino compound 17521
                                        aromatic amine 14915
                                          anilines 13987
                                            substituted aniline 13665
                                              sulfanilamide 249
                                                sulfisomidine 2
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