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ONTOLOGY REPORT - ANNOTATIONS


Term:sulfamethoxazole
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Accession:CHEBI:9332 term browser browse the term
Definition:An isoxazole (1,2-oxazole) compound having a methyl substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 3-position.
Synonyms:exact_synonym: 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide
 related_synonym: 3-(p-Aminophenylsulfonamido)-5-methylisoxazole;   3-Sulfanilamido-5-methylisoxazole;   4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide;   Formula=C10H11N3O3S;   Gantanol (TN);   InChI=1S/C10H11N3O3S/c1-7-6-10(12-16-7)13-17(14,15)9-4-2-8(11)3-5-9/h2-6H,11H2,1H3,(H,12,13);   InChIKey=JLKIGFTWXXRPMT-UHFFFAOYSA-N;   SMILES=C=1(C=CC(=CC1)N)S(NC=2C=C(ON2)C)(=O)=O;   SMX;   sulphamethoxazole
 alt_id: CHEBI:102247
 xref: CAS:723-46-6 "ChemIDplus";   CAS:723-46-6 "DrugBank";   CAS:723-46-6 "KEGG COMPOUND";   DrugBank:DB01015;   Drug_Central:2514 "DrugCentral";   Gmelin:226453 "Gmelin";   HMDB:HMDB0015150;   KEGG:C07315;   KEGG:D00447;   LINCS:LSM-5422
 xref_mesh: MESH:D013420
 xref: PMID:10843725 "Europe PMC";   PMID:10891117 "ChEMBL";   PMID:10969989 "ChEMBL";   PMID:11350866 "Europe PMC";   PMID:11431418 "Europe PMC";   PMID:12019187 "Europe PMC";   PMID:15497867 "Europe PMC";   PMID:15588915 "Europe PMC";   PMID:15967282 "Europe PMC";   PMID:15984773 "Europe PMC";   PMID:17095123 "Europe PMC";   PMID:17110110 "ChEMBL";   PMID:17158933 "ChEMBL";   PMID:17311370 "ChEMBL";   PMID:17442935 "Europe PMC";   PMID:17573190 "Europe PMC";   PMID:18334600 "Europe PMC";   PMID:18958736 "Europe PMC";   PMID:19436870 "Europe PMC";   PMID:20564608 "Europe PMC";   PMID:22534821 "Europe PMC";   PMID:226453 "Europe PMC";   PMID:23611245 "Europe PMC";   PMID:23649399 "Europe PMC";   PMID:23742687 "Europe PMC";   PMID:25851465 "Europe PMC";   PMID:313909 "Europe PMC";   PMID:3906132 "ChEMBL";   PMID:6864729 "ChEMBL";   PMID:7486915 "Europe PMC";   PMID:7490723 "ChEMBL";   PMID:7534104 "Europe PMC";   PMID:7602118 "Europe PMC";   PMID:7731020 "ChEMBL";   PMID:7798534 "Europe PMC";   PMID:8208693 "Europe PMC";   PMID:8632413 "ChEMBL";   Reaxys:226453 "Reaxys";   Wikipedia:Sulfamethoxazole


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sulfamethoxazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Acan aggrecan JBrowse link 1 140,762,758 140,824,441 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6480464
G Mir155 microRNA 155 JBrowse link 11 24,176,603 24,176,667 RGD:6480464
G Mir18a microRNA 18a JBrowse link 15 100,180,015 100,180,110 RGD:6480464
G Mir21 microRNA 21 JBrowse link 10 73,902,210 73,902,301 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:6480464
G Phyh phytanoyl-CoA 2-hydroxylase JBrowse link 17 77,287,580 77,304,482 RGD:6480464
G Pir pirin JBrowse link X 31,852,322 31,968,152 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:6480464
co-trimoxazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
nitrososulfamethoxazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Srxn1 sulfiredoxin 1 JBrowse link 3 147,608,850 147,614,410 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:6480464
sulfamethoxazole hydroxylamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyb5b cytochrome b5 type B JBrowse link 19 39,357,814 39,391,680 RGD:6480464
G Cyb5r3 cytochrome b5 reductase 3 JBrowse link 7 124,024,003 124,041,564 RGD:6480464
G Mtarc1 mitochondrial amidoxime reducing component 1 JBrowse link 13 102,693,679 102,724,120 RGD:6480464
G Mtarc2 mitochondrial amidoxime reducing component 2 JBrowse link 13 102,724,266 102,755,511 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        antimicrobial agent 17151
          sulfamethoxazole 32
            N-acetylsulfamethoxazole 0
            co-trimoxazole 1
            nitrososulfamethoxazole 13
            sulfamethoxazole hydroxylamine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        aromatic amine 13572
                                          anilines 12285
                                            substituted aniline 11780
                                              sulfanilamide 189
                                                sulfamethoxazole 32
                                                  N-acetylsulfamethoxazole 0
                                                  co-trimoxazole 1
                                                  nitrososulfamethoxazole 13
                                                  sulfamethoxazole hydroxylamine 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.