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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2502
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyb5r3
Name: cytochrome b5 reductase 3
Acc ID: CHEBI:53016
Term: sulfamethoxazole hydroxylamine
Definition: A sulfonamide compound having a 4-hydroxylaminophenyl group attached to the sulfur atom and a 1,2-oxazol-3-yl group attached to the nitrogen atom.
Chemical ID: MESH:C059873
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyb5r3multiple interactionsISORGD:7317316480464CTD[MTARC1 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine; [MTARC2 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylaminePMID:25170804
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