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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfamethoxazole hydroxylamine
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Accession:CHEBI:53016 term browser browse the term
Definition:A sulfonamide compound having a 4-hydroxylaminophenyl group attached to the sulfur atom and a 1,2-oxazol-3-yl group attached to the nitrogen atom.
Synonyms:exact_synonym: 4-(hydroxyamino)-N-(5-methylisoxazol-3-yl)benzenesulfonamide
 related_synonym: 4-(Hydroxyamino)-N-(5-methyl-3-isoxazolyl)benzenesulfonamide;   Formula=C10H11N3O4S;   InChI=1S/C10H11N3O4S/c1-7-6-10(12-17-7)13-18(15,16)9-4-2-8(11-14)3-5-9/h2-6,11,14H,1H3,(H,12,13);   InChIKey=MJAMPGKHIZXVFJ-UHFFFAOYSA-N;   SMILES=Cc1cc(NS(=O)(=O)c2ccc(NO)cc2)no1;   SMX-NHOH;   Smx-HA
 xref: Beilstein:6336217;   CAS:114438-33-4
 xref_mesh: MESH:C059873
 xref: PMID:10506572;   PMID:10843725;   PMID:11350866;   PMID:11448455;   PMID:15588915;   PMID:16473451;   PMID:1686233;   PMID:1997005;   PMID:1997006;   PMID:19997042;   PMID:20221587;   PMID:7628308;   PMID:8062495;   Reaxys:6336217



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sulfamethoxazole hydroxylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyb5b cytochrome b5 type B multiple interactions ISO [MTARC1 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine; [MTARC2 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine CTD PMID:25170804 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 multiple interactions ISO [MTARC1 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine; [MTARC2 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine CTD PMID:25170804 NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 multiple interactions ISO [MTARC1 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine CTD PMID:25170804 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 multiple interactions ISO [MTARC2 protein co-treated with CYB5B protein co-treated with CYB5R3 protein co-treated with NAD] results in increased reduction of sulfamethoxazole hydroxylamine CTD PMID:25170804 NCBI chr13:96,362,810...96,397,284 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19904
    role 19880
      biological role 19878
        biochemical role 19576
          metabolite 19562
            sulfamethoxazole hydroxylamine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19904
    subatomic particle 19902
      composite particle 19902
        hadron 19902
          baryon 19902
            nucleon 19902
              atomic nucleus 19902
                atom 19902
                  main group element atom 19852
                    main group molecular entity 19852
                      s-block molecular entity 19684
                        hydrogen molecular entity 19670
                          hydrides 19149
                            inorganic hydride 18128
                              pnictogen hydride 18117
                                nitrogen hydride 18020
                                  azane 17819
                                    ammonia 17818
                                      organic amino compound 17818
                                        aromatic amine 15425
                                          anilines 14439
                                            substituted aniline 14080
                                              sulfanilamide 2922
                                                sulfamethoxazole 33
                                                  sulfamethoxazole hydroxylamine 4
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