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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:3770 term browser browse the term
Definition:A two-component mixture comprising trimethoprim and sulfamethoxazole.
Synonyms:exact_synonym: 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide - 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine (1:1)
 related_synonym: Bactrim;   Cotrimoxazol;   Cotrimoxazole;   Septra;   Sulfamethoxazole - trimethoprim mixture;   Sulfamethoxazole and trimethoprim;   Sulfamethoxazole mixture with trimethoprim;   Trimethoprim and sulphamethoxazole;   Trimethoprim-sulfamethoxazole;   Trimethoprim-sulfamethoxazole combination;   sulfamethoxazol/trimetoprim
 xref: CAS:8064-90-2;   KEGG:D00285
 xref_mesh: MESH:D015662
 xref: PMID:10737909;   PMID:11120976;   PMID:445303;   PMID:9756768;   Reaxys:5236098;   Wikipedia:Trimethoprim/sulfamethoxazole

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co-trimoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 increases secretion ISO Trimethoprim, Sulfamethoxazole Drug Combination results in increased secretion of INS protein modified form CTD PMID:14714756 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    role 19713
      biological role 19711
        antimicrobial agent 17880
          co-trimoxazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    main group molecular entity 19686
                      s-block molecular entity 19541
                        hydrogen molecular entity 19534
                          hydrides 19019
                            inorganic hydride 17950
                              pnictogen hydride 17935
                                nitrogen hydride 17832
                                  azane 17616
                                    ammonia 17615
                                      organic amino compound 17615
                                        aromatic amine 15002
                                          anilines 13972
                                            substituted aniline 13646
                                              sulfanilamide 263
                                                sulfamethoxazole 33
                                                  co-trimoxazole 1
paths to the root