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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:3770 term browser browse the term
Definition:A two-component mixture comprising trimethoprim and sulfamethoxazole.
Synonyms:exact_synonym: 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide - 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine (1:1)
 related_synonym: Bactrim;   Cotrimoxazol;   Cotrimoxazole;   Septra;   Sulfamethoxazole - trimethoprim mixture;   Sulfamethoxazole and trimethoprim;   Sulfamethoxazole mixture with trimethoprim;   Trimethoprim and sulphamethoxazole;   Trimethoprim-sulfamethoxazole;   Trimethoprim-sulfamethoxazole combination;   sulfamethoxazol/trimetoprim
 xref: CAS:8064-90-2;   KEGG:D00285
 xref_mesh: MESH:D015662
 xref: PMID:10737909;   PMID:11120976;   PMID:445303;   PMID:9756768;   Reaxys:5236098;   Wikipedia:Trimethoprim/sulfamethoxazole

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co-trimoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 increases secretion ISO Trimethoprim, Sulfamethoxazole Drug Combination results in increased secretion of INS protein modified form CTD PMID:14714756 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        antimicrobial agent 17309
          co-trimoxazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19428
                        hydrogen molecular entity 19418
                          hydrides 18685
                            inorganic hydride 17409
                              pnictogen hydride 17381
                                nitrogen hydride 17223
                                  azane 16940
                                    ammonia 16939
                                      organic amino compound 16938
                                        aromatic amine 13616
                                          anilines 12327
                                            substituted aniline 11823
                                              sulfanilamide 243
                                                sulfamethoxazole 31
                                                  co-trimoxazole 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.