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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:3770 term browser browse the term
Definition:A two-component mixture comprising trimethoprim and sulfamethoxazole.
Synonyms:exact_synonym: 4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide - 5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine (1:1)
 related_synonym: Bactrim;   Cotrimoxazol;   Cotrimoxazole;   Septra;   Sulfamethoxazole - trimethoprim mixture;   Sulfamethoxazole and trimethoprim;   Sulfamethoxazole mixture with trimethoprim;   Trimethoprim and sulphamethoxazole;   Trimethoprim-sulfamethoxazole;   Trimethoprim-sulfamethoxazole combination;   sulfamethoxazol/trimetoprim
 xref: CAS:8064-90-2;   KEGG:D00285
 xref_mesh: MESH:D015662
 xref: PMID:10737909;   PMID:11120976;   PMID:445303;   PMID:9756768;   Reaxys:5236098;   Wikipedia:Trimethoprim/sulfamethoxazole

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co-trimoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 increases secretion ISO Trimethoprim, Sulfamethoxazole Drug Combination results in increased secretion of INS protein modified form CTD PMID:14714756 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        antimicrobial agent 17400
          co-trimoxazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        aromatic amine 13701
                                          anilines 12359
                                            substituted aniline 11852
                                              sulfanilamide 249
                                                sulfamethoxazole 32
                                                  co-trimoxazole 1
paths to the root