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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfamerazine
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Accession:CHEBI:102130 term browser browse the term
Definition:A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position.
Synonyms:exact_synonym: 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
 related_synonym: (p-Aminobenzolsulfonyl)-2-amino-4-methylpyrimidin;   2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine;   2-(Sulfanilamido)-4-methylpyrimidine;   2-(p-Aminobenzolsulfonamido)-4-methylpyrimidine;   2-Sulfa-4-methylpyrimidine;   4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide;   Formula=C11H12N4O2S;   InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15);   InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N;   N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide;   N-(4-Methyl-2-pyrimidyl)sulfanilamide;   SMILES=Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1;   Sulfamethyldiazine;   Sulphamerazine;   sulfamerazina;   sulfamerazinum
 xref: Beilstein:249133;   CAS:127-79-7;   DrugBank:DB01581;   Drug_Central:2510;   Gmelin:219949;   KEGG:D02435;   LINCS:LSM-5979
 xref_mesh: MESH:D013416
 xref: PMID:11431418;   PMID:13037579;   PMID:23627444;   PMID:2434548;   PMID:24508883;   PMID:6864729;   Patent:US2407966;   Wikipedia:Sulfamerazine


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sulfamerazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity
increases activity
EXP Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein
RGD PMID:6893114, PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,631,425...47,685,379
Ensembl chr10:47,632,192...47,666,921
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:47,587,909...47,631,373
Ensembl chr10:47,588,497...47,630,799
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19883
    role 19833
      biological role 19833
        antimicrobial agent 17416
          sulfonamide antibiotic 251
            sulfamerazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19883
    subatomic particle 19881
      composite particle 19881
        hadron 19881
          baryon 19881
            nucleon 19881
              atomic nucleus 19881
                atom 19881
                  main group element atom 19771
                    main group molecular entity 19771
                      s-block molecular entity 19520
                        hydrogen molecular entity 19512
                          hydrides 18784
                            inorganic hydride 17511
                              pnictogen hydride 17484
                                nitrogen hydride 17327
                                  azane 17043
                                    ammonia 17042
                                      organic amino compound 17041
                                        aromatic amine 13692
                                          anilines 12365
                                            substituted aniline 11861
                                              sulfanilamide 246
                                                sulfamerazine 3
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