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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfamerazine
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Accession:CHEBI:102130 term browser browse the term
Definition:A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position.
Synonyms:exact_synonym: 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
 related_synonym: (p-Aminobenzolsulfonyl)-2-amino-4-methylpyrimidin;   2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine;   2-(Sulfanilamido)-4-methylpyrimidine;   2-(p-Aminobenzolsulfonamido)-4-methylpyrimidine;   2-Sulfa-4-methylpyrimidine;   4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide;   Formula=C11H12N4O2S;   InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15);   InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N;   N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide;   N-(4-Methyl-2-pyrimidyl)sulfanilamide;   SMILES=Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1;   Sulfamethyldiazine;   Sulphamerazine;   sulfamerazina;   sulfamerazinum
 xref: Beilstein:249133;   CAS:127-79-7;   DrugBank:DB01581;   Drug_Central:2510;   Gmelin:219949;   KEGG:D02435;   LINCS:LSM-5979
 xref_mesh: MESH:D013416
 xref: PMID:11431418;   PMID:13037579;   PMID:23627444;   PMID:2434548;   PMID:24508883;   PMID:6864729;   Patent:US2407966;   Wikipedia:Sulfamerazine



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sulfamerazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity
increases activity
EXP Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein
RGD PMID:6893114 PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      biological role 20011
        antimicrobial agent 17818
          sulfonamide antibiotic 256
            sulfamerazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    main group molecular entity 19960
                      s-block molecular entity 19784
                        hydrogen molecular entity 19777
                          hydrides 19115
                            inorganic hydride 17901
                              pnictogen hydride 17884
                                nitrogen hydride 17773
                                  azane 17503
                                    ammonia 17521
                                      organic amino compound 17521
                                        aromatic amine 14915
                                          anilines 13987
                                            substituted aniline 13665
                                              sulfanilamide 249
                                                sulfamerazine 3
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