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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sulfamerazine
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Accession:CHEBI:102130 term browser browse the term
Definition:A sulfonamide consisting of pyrimidine with a methyl substituent at the 4-position and a 4-aminobenzenesulfonamido group at the 2-position.
Synonyms:exact_synonym: 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
 related_synonym: (p-Aminobenzolsulfonyl)-2-amino-4-methylpyrimidin;   2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine;   2-(Sulfanilamido)-4-methylpyrimidine;   2-(p-Aminobenzolsulfonamido)-4-methylpyrimidine;   2-Sulfa-4-methylpyrimidine;   4-Amino-N-(4-methyl-2-pyrimidinyl)-benzenesulfonamide;   Formula=C11H12N4O2S;   InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15);   InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N;   N(1)-(4-Methyl-2-pyrimidinyl)sulfanilamide;   N-(4-Methyl-2-pyrimidyl)sulfanilamide;   SMILES=Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1;   Sulfamethyldiazine;   Sulphamerazine;   sulfamerazina;   sulfamerazinum
 xref: Beilstein:249133;   CAS:127-79-7;   DrugBank:DB01581;   Drug_Central:2510;   Gmelin:219949;   KEGG:D02435;   LINCS:LSM-5979
 xref_mesh: MESH:D013416
 xref: PMID:11431418;   PMID:13037579;   PMID:23627444;   PMID:2434548;   PMID:24508883;   PMID:6864729;   Patent:US2407966;   Wikipedia:Sulfamerazine


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sulfamerazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity
increases activity		 EXP Sulfamerazine decreases activity of purified Hmbs protein
Sulfamerazine increases activity of purified Hmbs protein		 RGD PMID:6893114 PMID:3702597 RGD:26923963, RGD:4144820 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Sulfamerazine affects the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19932
    role 19904
      biological role 19902
        antimicrobial agent 18269
          sulfonamide antibiotic 2937
            sulfamerazine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    main group molecular entity 19876
                      s-block molecular entity 19705
                        hydrogen molecular entity 19686
                          hydrides 19179
                            inorganic hydride 18191
                              pnictogen hydride 18181
                                nitrogen hydride 18092
                                  azane 17895
                                    ammonia 17894
                                      organic amino compound 17894
                                        aromatic amine 15496
                                          anilines 14428
                                            substituted aniline 14070
                                              sulfanilamide 2932
                                                sulfamerazine 3
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