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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:cytokine-mediated signaling pathway
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Accession:GO:0019221 term browser browse the term
Definition:The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: cytokine and chemokine mediated signaling pathway;   cytokine mediated signalling pathway


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cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAD BCL2 associated agonist of cell death involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14967141) Ensembl
MGI		 PMID:14967141 GO_REF:0000107 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G CAV1 caveolin 1 acts_upstream_of ISO (PMID:12388746) MGI PMID:12388746 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 involved_in ISO (PMID:12207323) RGD
BHF-UCL		 PMID:12207323 PMID:16174730 RGD:1625370 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCR2 C-C motif chemokine receptor 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15995708) RGD
Ensembl
MGI		 PMID:15995708 PMID:16174730 GO_REF:0000107 RGD:1625370 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698 		JBrowse link
G CD44 CD44 molecule involved_in IEA GOC GO_REF:0000108 NCBI chr18:32,735,493...32,826,483
Ensembl chr18:32,737,907...32,827,107 		JBrowse link
G CD74 CD74 molecule involved_in IEA GOC GO_REF:0000108 NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151 		JBrowse link
G CISH cytokine inducible SH2 containing protein ISO RGD PMID:10579313 RGD:724748 NCBI chr20:38,762,239...38,767,701
Ensembl chr20:38,762,378...38,766,620 		JBrowse link
G CKAP2L cytoskeleton associated protein 2 like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:36,932,689...36,964,623
Ensembl chr17:36,932,810...36,973,248 		JBrowse link
G CNOT9 CCR4-NOT transcription complex subunit 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10880228) Ensembl
MGI		 PMID:10880228 GO_REF:0000107 NCBI chr37:25,186,928...25,213,255
Ensembl chr37:25,187,066...25,212,642 		JBrowse link
G CNTFR ciliary neurotrophic factor receptor involved_in IEA GOC GO_REF:0000108 NCBI chr11:51,226,951...51,266,431
Ensembl chr11:51,227,509...51,245,188 		JBrowse link
G COQ8B coenzyme Q8B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,056,369...113,075,773
Ensembl chr 1:113,057,141...113,102,074 		JBrowse link
G CRLF1 cytokine receptor like factor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:44,466,812...44,476,055
Ensembl chr20:44,466,810...44,472,637 		JBrowse link
G CRLF2 cytokine receptor like factor 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:780,924...801,961
Ensembl chr  X:780,711...802,836 		JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G CSF2RA colony stimulating factor 2 receptor subunit alpha involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr  X:832,170...855,548
Ensembl chr  X:832,046...853,876 		JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr10:27,541,645...27,566,907
Ensembl chr10:27,541,647...27,567,278 		JBrowse link
G CSF3R colony stimulating factor 3 receptor involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr15:5,818,985...5,832,455
Ensembl chr15:5,822,025...5,831,882 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18971423) Ensembl
MGI		 PMID:18971423 GO_REF:0000107 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808 		JBrowse link
G DDX4 DEAD-box helicase 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:43,026,367...43,109,546
Ensembl chr 2:43,027,296...43,109,526 		JBrowse link
G DUOX1 dual oxidase 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr30:11,556,024...11,588,203
Ensembl chr30:11,556,024...11,588,202 		JBrowse link
G DUOX2 dual oxidase 2 involved_in ISO (PMID:16111680) UniProt PMID:16111680 NCBI chr30:11,521,833...11,541,719
Ensembl chr30:11,521,845...11,541,716 		JBrowse link
G EBI3 Epstein-Barr virus induced 3 involved_in IEA GOC GO_REF:0000108 NCBI chr20:55,382,975...55,391,252
Ensembl chr20:55,383,247...55,390,336 		JBrowse link
G EDA ectodysplasin A involved_in ISO (PMID:27144394)
(PMID:11039935)		 UniProt
ARUK-UCL		 PMID:11039935 PMID:27144394 NCBI chr  X:54,078,694...54,515,535
Ensembl chr  X:54,078,966...54,515,535 		JBrowse link
G EDAR ectodysplasin A receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:34,873,311...34,943,140
Ensembl chr10:34,848,526...34,940,784 		JBrowse link
G EDN2 endothelin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:1,647,966...1,654,272
Ensembl chr15:1,648,077...1,654,272 		JBrowse link
G EPOR erythropoietin receptor involved_in IEA
IBA		 GOC
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000108 GO_REF:0000118 NCBI chr20:49,945,777...49,950,856
Ensembl chr20:49,945,777...49,950,856 		JBrowse link
G EREG epiregulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:62,857,325...62,877,831
Ensembl chr13:62,856,709...62,877,760 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:54,709,581...54,720,603
Ensembl chr 6:54,708,471...54,720,607 		JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999 		JBrowse link
G FKBP1A FKBP prolyl isomerase 1A acts_upstream_of_or_within ISO (PMID:14605212) MGI PMID:14605212 NCBI chr24:19,618,581...19,643,685
Ensembl chr24:19,618,558...19,643,046 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30990796) Ensembl
MGI		 PMID:30990796 GO_REF:0000107 NCBI chr18:51,366,719...51,374,411
Ensembl chr18:51,368,352...51,373,748 		JBrowse link
G FZD4 frizzled class receptor 4 involved_in IEA GOC GO_REF:0000108 NCBI chr21:12,699,886...12,709,132
Ensembl chr21:12,699,774...12,724,923 		JBrowse link
G GALT galactose-1-phosphate uridylyltransferase involved_in IEA GOC GO_REF:0000108 NCBI chr11:51,319,812...51,323,337
Ensembl chr11:51,319,347...51,334,802 		JBrowse link
G GHR growth hormone receptor involved_in IEA
IBA		 GOC
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000108 GO_REF:0000118 NCBI chr 4:67,021,821...67,245,499
Ensembl chr 4:67,022,252...67,290,473 		JBrowse link
G GREM2 gremlin 2, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:32,048,151...32,157,698
Ensembl chr 7:32,048,183...32,157,146 		JBrowse link
G IFNA5 interferon, alpha 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:40,726,568...40,727,131
Ensembl chr11:40,726,568...40,727,131 		JBrowse link
G IFNA6 interferon, alpha 6 involved_in IBA GO_Central GO_REF:0000033 Ensembl chr11:40,726,568...40,727,131 JBrowse link
G IFNA7 interferon, alpha 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:40,862,587...40,863,150
Ensembl chr11:40,862,587...40,863,150 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 involved_in ISO
IEA		 RGD
InterPro		 PMID:27999109 GO_REF:0000002 RGD:12910492 NCBI chr31:28,854,765...28,876,399 JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr31:27,860,094...27,891,361 JBrowse link
G IFNB1 interferon beta 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855 		JBrowse link
G IFNGR1 interferon gamma receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:29,646,776...29,669,669
Ensembl chr 1:29,647,552...29,669,578 		JBrowse link
G IFNGR2 interferon gamma receptor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr31:28,909,930...28,948,742 JBrowse link
G IFNK interferon kappa involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr11:45,641,627...45,642,256
Ensembl chr11:45,641,627...45,642,256 		JBrowse link
G IFNLR1 interferon lambda receptor 1 involved_in IEA TreeGrafter GO_REF:0000118
G IL10RA interleukin 10 receptor subunit alpha involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:15,675,775...15,688,935
Ensembl chr 5:15,677,547...15,682,163 		JBrowse link
G IL10RB interleukin 10 receptor subunit beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1196700|PMID:9463407) GOC
TreeGrafter		 PMID:9463407 GO_REF:0000118 MGI:1196700 NCBI chr31:28,791,541...28,815,163
Ensembl chr31:27,892,394...27,915,637 		JBrowse link
G IL11RA interleukin 11 receptor subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:7957045) MGI
TreeGrafter		 PMID:7957045 GO_REF:0000118 NCBI chr11:51,324,915...51,341,981 JBrowse link
G IL12B interleukin 12B involved_in IEA UniProt
GOC		 GO_REF:0000104 GO_REF:0000108 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:44,885,410...44,908,139
Ensembl chr20:44,885,337...44,904,538 		JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:43,197,034...43,269,571
Ensembl chr 5:43,197,034...43,257,594 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr  X:90,925,497...90,981,855
Ensembl chr  X:90,924,801...90,979,963 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 involved_in IEA
IBA		 GOC
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000108 GO_REF:0000118 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798 		JBrowse link
G IL16 interleukin 16 involved_in ISO (MGI:6414686|PMID:30089723) ARUK-UCL PMID:30089723 MGI:6414686 NCBI chr 3:56,473,485...56,575,504
Ensembl chr 3:56,473,486...56,575,104 		JBrowse link
G IL17RA interleukin 17 receptor A involved_in IEA GOC GO_REF:0000108 NCBI chr27:44,798,960...44,812,287
Ensembl chr27:44,791,066...44,811,064 		JBrowse link
G IL17RB interleukin 17 receptor B involved_in IEA GOC GO_REF:0000108 NCBI chr20:36,135,620...36,148,923
Ensembl chr20:36,135,619...36,148,490 		JBrowse link
G IL17RC interleukin 17 receptor C involved_in IEA GOC GO_REF:0000108 NCBI chr20:8,342,622...8,355,996
Ensembl chr20:8,334,345...8,355,387 		JBrowse link
G IL17RD interleukin 17 receptor D involved_in IEA GOC GO_REF:0000108 NCBI chr20:33,240,728...33,306,727
Ensembl chr20:33,240,767...33,303,404 		JBrowse link
G IL17RE interleukin 17 receptor E involved_in IEA GOC GO_REF:0000108 NCBI chr20:8,356,150...8,376,175
Ensembl chr20:8,356,728...8,367,658 		JBrowse link
G IL17REL interleukin 17 receptor E like involved_in IEA GOC GO_REF:0000108 NCBI chr10:17,238,418...17,242,686
Ensembl chr10:17,216,084...17,242,226 		JBrowse link
G IL18 interleukin 18 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL18R1 interleukin 18 receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454 		JBrowse link
G IL1A interleukin 1 alpha involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:36,969,581...36,979,445
Ensembl chr17:36,970,573...36,979,435 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1F10 interleukin 1 family member 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:37,192,357...37,202,519
Ensembl chr17:37,192,175...37,202,044 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11880380), (PMID:15292196) Ensembl
MGI		 PMID:11880380 PMID:15292196 GO_REF:0000107 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 involved_in IEA GOC GO_REF:0000108 NCBI chr10:40,967,532...41,003,659
Ensembl chr10:40,896,669...41,034,113 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11880380) Ensembl
MGI
GOC		 PMID:11880380 GO_REF:0000107 GO_REF:0000108 NCBI chr34:22,547,422...22,628,628
Ensembl chr34:22,546,899...22,623,544 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 involved_in IEA GOC GO_REF:0000108 NCBI chr10:40,658,191...40,732,097
Ensembl chr10:40,659,041...40,677,357 		JBrowse link
G IL1RL2 interleukin 1 receptor like 2 involved_in IEA GOC GO_REF:0000108 NCBI chr10:40,776,670...40,817,263
Ensembl chr10:40,778,590...40,816,044 		JBrowse link
G IL20RA interleukin 20 receptor subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21844205) Ensembl
TreeGrafter
MGI		 PMID:21844205 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:29,506,582...29,545,882
Ensembl chr 1:29,506,689...29,546,006 		JBrowse link
G IL20RB interleukin 20 receptor subunit beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr23:33,384,057...33,421,619
Ensembl chr23:33,384,486...33,420,016 		JBrowse link
G IL21R interleukin 21 receptor involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr 6:19,181,846...19,217,915
Ensembl chr 6:19,182,071...19,217,931 		JBrowse link
G IL22RA1 interleukin 22 receptor subunit alpha 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:75,454,087...75,475,211
Ensembl chr 2:75,454,164...75,474,218 		JBrowse link
G IL22RA2 interleukin 22 receptor subunit alpha 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:29,611,096...29,631,811
Ensembl chr 1:29,611,722...29,631,473 		JBrowse link
G IL23R interleukin 23 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:43,307,422...43,369,806
Ensembl chr 5:43,308,982...43,368,474 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:7736574) RGD
TreeGrafter
Ensembl
MGI		 PMID:1889461 PMID:7736574 GO_REF:0000107 GO_REF:0000118 RGD:728928 NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in IEA
IBA		 GOC
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000108 GO_REF:0000118 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G IL3 interleukin 3 acts_upstream_of_or_within ISO (PMID:7519779) MGI PMID:7519779 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668 		JBrowse link
G IL31RA interleukin 31 receptor A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:43,113,194...43,198,200
Ensembl chr 2:43,144,071...43,193,293 		JBrowse link
G IL36B interleukin 36 beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:37,159,276...37,165,841
Ensembl chr17:37,159,434...37,165,423 		JBrowse link
G IL36G interleukin 36 gamma involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:37,100,557...37,148,402
Ensembl chr17:37,144,309...37,149,400 		JBrowse link
G IL37 interleukin 37 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:36,964,857...37,101,005
Ensembl chr17:36,977,063...37,100,801 		JBrowse link
G IL3RA interleukin 3 receptor subunit alpha involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr  X:894,590...912,213
Ensembl chr  X:894,552...911,556 		JBrowse link
G IL4R interleukin 4 receptor involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G IL5 interleukin 5 ISO RGD PMID:10867506 PMID:11335106 RGD:2303510 RGD:2303751 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269 		JBrowse link
G IL5RA interleukin 5 receptor subunit alpha involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr20:14,309,805...14,349,433
Ensembl chr20:14,314,227...14,343,793 		JBrowse link
G IL6 interleukin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7957045) GOC
TreeGrafter
MGI
Ensembl		 PMID:7957045 GO_REF:0000107 GO_REF:0000108 GO_REF:0000118 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G IL7 interleukin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737 		JBrowse link
G IL7R interleukin 7 receptor involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr 4:72,633,528...72,668,242
Ensembl chr 4:72,636,325...72,668,300 		JBrowse link
G INHBA inhibin subunit beta A ISO RGD PMID:14993131 RGD:1580888 NCBI chr18:8,272,978...8,288,432
Ensembl chr18:8,272,872...8,283,794 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 acts_upstream_of_or_within ISO (PMID:15292196) RGD
MGI		 PMID:15292196 PMID:15890643 RGD:1579817 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15292196) RGD
MGI
Ensembl		 PMID:15292196 PMID:15890643 GO_REF:0000107 RGD:1579817 NCBI chr27:10,313,782...10,340,652
Ensembl chr27:10,314,187...10,340,682 		JBrowse link
G IRF5 interferon regulatory factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,724,168...7,734,976
Ensembl chr14:7,724,780...7,742,795 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:39,624,554...39,687,991 JBrowse link
G JAK1 Janus kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8022486) UniProt
MGI
TreeGrafter		 PMID:8022486 GO_REF:0000117 GO_REF:0000118 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000117 GO_REF:0000118 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G JAK3 Janus kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8022486) RGD
MGI
TreeGrafter
UniProt		 PMID:7518451 PMID:8022486 GO_REF:0000117 GO_REF:0000118 RGD:1600268 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:10872802) Ensembl
MGI
UniProt		 PMID:10872802 GO_REF:0000024 GO_REF:0000107 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G KLF6 KLF transcription factor 6 acts_upstream_of_or_within ISO (PMID:10880228) MGI PMID:10880228 NCBI chr 2:31,654,142...31,664,009
Ensembl chr 2:31,654,175...31,662,351 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:14576830 RGD:1600488 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LEPR leptin receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:44,684,118...44,775,626
Ensembl chr 5:44,688,109...44,775,636 		JBrowse link
G LIFR LIF receptor subunit alpha acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:7957045) MGI
TreeGrafter
GO_Central
Ensembl
GOC		 PMID:7957045 GO_REF:0000033 GO_REF:0000107 GO_REF:0000108 GO_REF:0000118 NCBI chr 4:70,328,963...70,376,127
Ensembl chr 4:70,267,514...70,376,127 		JBrowse link
G LOC100682977 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC100683045 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC100685213 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:40,816,731...40,817,513 JBrowse link
G LOC100686341 granulocyte-macrophage colony-stimulating factor receptor subunit alpha-like involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr  X:862,267...889,005 JBrowse link
G LOC100688005 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:40,762,074...40,762,872 JBrowse link
G LOC100688084 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:40,765,515...40,766,521 JBrowse link
G LOC119873921 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876805 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876806 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876807 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876808 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876809 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876810 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC119876811 interferon alpha-1/2 involved_in IBA GO_Central GO_REF:0000033
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:102,779,562...102,786,924 JBrowse link
G LOC484309 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:102,995,743...103,014,085 JBrowse link
G LOC611446 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12021780) TreeGrafter
MGI		 PMID:12021780 GO_REF:0000118 NCBI chr 1:102,955,916...102,978,669 JBrowse link
G LOC611642 interleukin-9 receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:40,425,072...40,437,917 JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor ISO RGD PMID:15890643 RGD:1579817 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:8,147,160...8,154,401
Ensembl chr33:8,073,840...8,154,561 		JBrowse link
G NUMBL NUMB like endocytic adaptor protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,076,678...113,103,114
Ensembl chr 1:113,057,141...113,102,074 		JBrowse link
G OSMR oncostatin M receptor involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr 4:70,016,384...70,067,098
Ensembl chr 4:70,018,022...70,055,216 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PRLR prolactin receptor involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:73,147,919...73,280,970
Ensembl chr 4:73,110,858...73,273,916 		JBrowse link
G RCL1 RNA terminal phosphate cyclase like 1 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000117 GO_REF:0000118 NCBI chr 1:93,144,164...93,204,233
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:11894097) Ensembl
MGI		 PMID:11894097 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10872802) Ensembl
MGI		 PMID:10872802 GO_REF:0000107 NCBI chr 6:7,795,756...7,820,010
Ensembl chr 6:7,795,373...7,819,843 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,898,274...92,978,260
Ensembl chr 1:92,898,274...92,978,260 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:9202126), (PMID:9202127)
(PMID:11606785)		 MGI PMID:9202126 PMID:9202127 PMID:11606785 NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:48,916,446...48,977,183
Ensembl chr10:48,972,842...48,974,452 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO (PMID:12872135) MGI PMID:12872135 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097), (PMID:12213961) TreeGrafter
MGI		 PMID:11894097 PMID:12213961 GO_REF:0000118 NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10485657) TreeGrafter
MGI		 PMID:10485657 GO_REF:0000118 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10485657) Ensembl
MGI
TreeGrafter		 PMID:10485657 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:18362439 GO_REF:0000118 RGD:2298568 NCBI chr10:1,232,515...1,247,011
Ensembl chr10:1,233,691...1,247,075 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A acts_upstream_of_or_within ISO (PMID:11588035) MGI PMID:11588035 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,029,861...68,070,901
Ensembl chr12:68,030,197...68,058,518 		JBrowse link
G TRAF6 TNF receptor associated factor 6 ISO RGD PMID:15890643 RGD:1579817 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G TYK2 tyrosine kinase 2 involved_in IEA UniProt
TreeGrafter		 GO_REF:0000117 GO_REF:0000118 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
G ZC3H15 zinc finger CCCH-type containing 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10880228) Ensembl
MGI		 PMID:10880228 GO_REF:0000107 NCBI chr36:28,730,213...28,743,884
Ensembl chr36:28,725,079...28,743,884 		JBrowse link
adiponectin-activated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL1 acyl-CoA synthetase long chain family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20667975) Ensembl
MGI		 PMID:20667975 GO_REF:0000107 NCBI chr16:45,735,675...45,806,235
Ensembl chr16:45,735,703...45,804,970 		JBrowse link
G ADIPOR1 adiponectin receptor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12802337) RGD
MGI
TreeGrafter		 PMID:12802337 PMID:18394428 GO_REF:0000118 RGD:2317907 NCBI chr 7:240,035...254,287
Ensembl chr 7:240,065...282,845 		JBrowse link
G ADIPOR2 adiponectin receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12802337) Ensembl
MGI
TreeGrafter		 PMID:12802337 GO_REF:0000107 GO_REF:0000118 NCBI chr27:43,739,269...43,840,116
Ensembl chr27:43,741,679...43,878,467 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,192,261...33,243,034
Ensembl chr10:33,191,602...33,242,669 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,149,467...1,154,417
Ensembl chr12:1,149,548...1,154,418 		JBrowse link
G KLHL12 kelch like family member 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:256,814...284,132 JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20667975) Ensembl
MGI
TreeGrafter		 PMID:20667975 GO_REF:0000107 GO_REF:0000118 NCBI chr20:45,309,094...45,341,101
Ensembl chr20:45,310,088...45,340,230 		JBrowse link
C-X-C chemokine receptor CXCR4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
chemokine (C-C motif) ligand 19 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCR7 C-C motif chemokine receptor 7 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656 		JBrowse link
chemokine (C-C motif) ligand 21 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCL21 C-C motif chemokine ligand 21 involved_in ISO (MGI:6141968|PMID:27400149) BHF-UCL PMID:27400149 MGI:6141968 NCBI chr11:51,375,107...51,375,790 JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656 		JBrowse link
G OXSR1 oxidative stress responsive kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,931,636...8,026,591
Ensembl chr23:7,932,254...8,024,323 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806 		JBrowse link
chemokine (C-X-C motif) ligand 12 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL12 C-X-C motif chemokine ligand 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:2,895,916...2,903,543 JBrowse link
G OXSR1 oxidative stress responsive kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,931,636...8,026,591
Ensembl chr23:7,932,254...8,024,323 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160 		JBrowse link
chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACKR1 atypical chemokine receptor 1 involved_in IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000104 NCBI chr38:22,762,584...22,765,330
Ensembl chr38:22,758,013...22,763,958 		JBrowse link
G ACKR2 atypical chemokine receptor 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr23:11,904,020...11,962,291
Ensembl chr23:11,960,981...11,962,135 		JBrowse link
G ACKR3 atypical chemokine receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:47,327,921...47,339,632
Ensembl chr25:47,327,963...47,339,622 		JBrowse link
G ACKR4 atypical chemokine receptor 4 involved_in IEA GOC GO_REF:0000108 NCBI chr23:29,586,250...29,591,627
Ensembl chr23:29,589,767...29,590,819 		JBrowse link
G AGTR1 angiotensin II receptor type 1 involved_in IEA GOC GO_REF:0000108
G AGTR2 angiotensin II receptor type 2 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853 		JBrowse link
G APLNR apelin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr18:38,878,621...38,882,280
Ensembl chr18:38,878,947...38,886,206 		JBrowse link
G BDKRB1 bradykinin receptor B1 involved_in IEA GOC GO_REF:0000108 NCBI chr 8:65,017,655...65,028,899 JBrowse link
G BDKRB2 bradykinin receptor B2 involved_in IEA GOC GO_REF:0000108 NCBI chr 8:64,974,588...65,005,682
Ensembl chr 8:64,974,997...65,003,407 		JBrowse link
G CCL13 chemokine (C-C motif) ligand 13 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:38,938,944...38,940,231
Ensembl chr 9:38,938,135...38,940,231 		JBrowse link
G CCL17 C-C motif chemokine ligand 17 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,001,463...59,014,347
Ensembl chr 2:59,001,464...59,005,230 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 involved_in ISO
IBA		 RGD
GO_Central		 PMID:18584881 GO_REF:0000033 RGD:2303073 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCL20 C-C motif chemokine ligand 20 involved_in IBA GO_Central GO_REF:0000033 NCBI chr25:40,506,385...40,509,903
Ensembl chr25:40,506,753...40,509,709 		JBrowse link
G CCL24 C-C motif chemokine ligand 24 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:7,166,165...7,179,606
Ensembl chr 6:7,166,479...7,180,051 		JBrowse link
G CCL25 C-C motif chemokine ligand 25 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:52,689,674...52,722,291
Ensembl chr20:52,712,979...52,722,018 		JBrowse link
G CCL26 C-C motif chemokine ligand 26 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:7,151,352...7,154,509
Ensembl chr 6:7,151,212...7,154,726 		JBrowse link
G CCL3 chemokine (C-C motif) ligand 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:37,693,711...37,695,137
Ensembl chr 9:37,686,480...37,695,573 		JBrowse link
G CCL4 chemokine (C-C motif) ligand 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:37,681,342...37,682,691
Ensembl chr 9:37,676,966...37,710,209 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:37,817,409...37,823,852
Ensembl chr 9:37,817,305...37,823,852 		JBrowse link
G CCL8 C-C motif chemokine ligand 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:38,949,184...38,950,702
Ensembl chr 9:38,948,184...38,950,803 		JBrowse link
G CCR1 chemokine (C-C motif) receptor 1 involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr20:42,421,356...42,427,177
Ensembl chr20:42,421,356...42,426,958 		JBrowse link
G CCR10 C-C motif chemokine receptor 10 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1354873|PMID:10725696) GOC
GOC		 PMID:10725696 GO_REF:0000108 MGI:1354873 NCBI chr 9:20,307,755...20,312,613
Ensembl chr 9:20,307,584...20,311,464 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:79768|PMID:8631787) RGD
GOC
GOC		 PMID:8631787 PMID:18584881 GO_REF:0000108 MGI:79768 RGD:2303073 NCBI chr20:42,305,344...42,313,258
Ensembl chr20:42,307,580...42,308,698 		JBrowse link
G CCR3 C-C motif chemokine receptor 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:77397|PMID:7594543) GOC
GOC		 PMID:7594543 GO_REF:0000108 MGI:77397 NCBI chr20:42,382,380...42,398,449
Ensembl chr20:42,383,135...42,384,217 		JBrowse link
G CCR4 C-C motif chemokine receptor 4 involved_in IEA GOC GO_REF:0000108 NCBI chr23:3,844,072...3,847,770
Ensembl chr23:3,844,173...3,845,255 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 involved_in IEA GOC GO_REF:0000108 NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:54,932,798...54,960,646
Ensembl chr 1:54,932,690...54,959,740 		JBrowse link
G CCR6 C-C motif chemokine receptor 6 involved_in IEA GOC GO_REF:0000108
G CCR7 C-C motif chemokine receptor 7 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:22,077,976...22,092,818
Ensembl chr 9:22,068,775...22,090,656 		JBrowse link
G CCR9 C-C motif chemokine receptor 9 involved_in IEA GOC GO_REF:0000108 NCBI chr20:42,607,024...42,616,823
Ensembl chr20:42,607,024...42,616,823 		JBrowse link
G CCRL2 C-C motif chemokine receptor like 2 involved_in IEA GOC GO_REF:0000108 NCBI chr20:42,270,431...42,272,498
Ensembl chr20:42,270,477...42,271,526 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr23:8,937,069...8,954,738
Ensembl chr23:8,938,906...8,952,808 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr32:598,406...599,925
Ensembl chr32:597,987...599,979 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 involved_in ISO (PMID:18645041) UniProt PMID:18645041 NCBI chr32:631,084...636,997
Ensembl chr32:631,478...632,868
Ensembl chr32:631,478...632,868 		JBrowse link
G CXCL11 C-X-C motif chemokine ligand 11 involved_in IEA Ensembl GO_REF:0000107
G CXCL12 C-X-C motif chemokine ligand 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:2,895,916...2,903,543 JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354 		JBrowse link
G CXCR1 chemokine (C-X-C motif) receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr37:24,862,129...24,866,069 JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:55,882,433...55,884,582
Ensembl chr  X:55,882,433...55,884,582 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 involved_in IEA UniProt GO_REF:0000117 NCBI chr19:38,874,650...38,877,740
Ensembl chr19:38,874,145...38,877,740 		JBrowse link
G CXCR5 C-X-C motif chemokine receptor 5 involved_in IEA GOC GO_REF:0000108 NCBI chr 5:14,921,447...14,932,937
Ensembl chr 5:14,923,089...14,932,762 		JBrowse link
G CXCR6 C-X-C motif chemokine receptor 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1891794|PMID:11017100) GOC
GOC		 PMID:11017100 GO_REF:0000108 MGI:1891794 NCBI chr20:42,565,251...42,569,647
Ensembl chr20:42,565,251...42,566,276 		JBrowse link
G FOXC1 forkhead box C1 involved_in ISO (MGI:3773495|PMID:18187037) UniProt PMID:18187037 MGI:3773495
G GPR15 G protein-coupled receptor 15 involved_in IEA GOC GO_REF:0000108 NCBI chr33:5,368,509...5,380,024
Ensembl chr33:5,396,083...5,397,165
Ensembl chr33:5,396,083...5,397,165 		JBrowse link
G GPR25 G protein-coupled receptor 25 involved_in IEA GOC GO_REF:0000108
G GPR35 G protein-coupled receptor 35 involved_in ISO (PMID:25411203) MGI PMID:25411203 NCBI chr25:50,566,263...50,841,473 JBrowse link
G GPR75 G protein-coupled receptor 75 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:54,858,380...54,862,734 JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G RXFP3 relaxin family peptide receptor 3 involved_in IEA GOC GO_REF:0000108
G TFF2 trefoil factor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:19064997) GO_Central
MGI
TreeGrafter		 PMID:19064997 GO_REF:0000033 GO_REF:0000118 NCBI chr31:36,665,647...36,668,423
Ensembl chr31:36,665,514...36,668,440 		JBrowse link
G XCR1 X-C motif chemokine receptor 1 involved_in IEA GOC GO_REF:0000108 NCBI chr20:42,505,534...42,516,524
Ensembl chr20:42,511,431...42,512,423 		JBrowse link
ciliary neurotrophic factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNTF ciliary neurotrophic factor involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr18:37,758,148...37,765,698 JBrowse link
G CNTFR ciliary neurotrophic factor receptor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:7585948) Ensembl
TreeGrafter
MGI
GO_Central		 PMID:7585948 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr11:51,226,951...51,266,431
Ensembl chr11:51,227,509...51,245,188 		JBrowse link
G IL6R interleukin 6 receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G LIFR LIF receptor subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:70,328,963...70,376,127
Ensembl chr 4:70,267,514...70,376,127 		JBrowse link
G ZFP91 ZFP91 zinc finger protein, atypical E3 ubiquitin ligase involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr18:37,762,200...37,809,070 JBrowse link
CXCL12-activated CXCR4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL12 C-X-C motif chemokine ligand 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:2,895,916...2,903,543 JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:31845480) UniProt
MGI		 PMID:31845480 GO_REF:0000024 NCBI chr19:38,874,650...38,877,740
Ensembl chr19:38,874,145...38,877,740 		JBrowse link
G ENTREP1 endosomal transmembrane epsin interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,004,174...88,067,491
Ensembl chr 1:88,004,615...88,067,495 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 acts_upstream_of_or_within_positive_effect ISO (PMID:33097708) ARUK-UCL PMID:33097708 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174 		JBrowse link
G WBP1L WW domain binding protein 1 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31845480) Ensembl
MGI		 PMID:31845480 GO_REF:0000107 NCBI chr28:15,218,883...15,285,211
Ensembl chr28:15,218,775...15,282,416 		JBrowse link
erythropoietin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EPO erythropoietin involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:8,994,211...8,995,954
Ensembl chr 6:8,994,211...8,996,144 		JBrowse link
G EPOR erythropoietin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr20:49,945,777...49,950,856
Ensembl chr20:49,945,777...49,950,856 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:90,925,497...90,981,855
Ensembl chr  X:90,924,801...90,979,963 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 involved_in IEA GOC GO_REF:0000108 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G RHEX regulator of hemoglobinization and erythroid cell expansion involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,416,825...2,434,203
Ensembl chr38:2,416,749...2,433,831 		JBrowse link
granulocyte colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:4837548|PMID:21029969) UniProt PMID:21029969 MGI:4837548 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G CSF3 colony stimulating factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,529,643...22,532,326
Ensembl chr 9:22,530,698...22,533,108 		JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in ISO (PMID:23001182) BHF-UCL PMID:23001182 NCBI chr 7:42,969,711...42,972,783
Ensembl chr 7:42,969,713...42,972,710 		JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:24,901,023...24,925,710
Ensembl chr33:24,901,287...24,922,923 		JBrowse link
G JAGN1 jagunal homolog 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:8,372,981...8,376,089
Ensembl chr20:8,373,316...8,376,085 		JBrowse link
granulocyte-macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF2 colony stimulating factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,342,880...20,346,959
Ensembl chr11:20,344,648...20,346,959 		JBrowse link
G CSF2RA colony stimulating factor 2 receptor subunit alpha involved_in ISO (PMID:18692472) ComplexPortal PMID:18692472 NCBI chr  X:832,170...855,548
Ensembl chr  X:832,046...853,876 		JBrowse link
G CSF2RB colony stimulating factor 2 receptor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,541,645...27,566,907
Ensembl chr10:27,541,647...27,567,278 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGR1 early growth response 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,359,551...23,419,114
Ensembl chr16:23,359,813...23,419,075 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G IL1R1 interleukin 1 receptor type 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
GOC		 PMID:20967881 GO_REF:0000107 GO_REF:0000108 GO_REF:0000118 RGD:5130945 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596 		JBrowse link
G IL1RAP interleukin 1 receptor accessory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:22,547,422...22,628,628
Ensembl chr34:22,546,899...22,623,544 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 NOT|involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11397809)
(PMID:12054681)		 UniProt
MGI
Ensembl		 PMID:11397809 PMID:12054681 GO_REF:0000107 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:8,133,987...8,197,009
Ensembl chr20:8,134,970...8,196,910 		JBrowse link
G IRAK3 interleukin 1 receptor associated kinase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12054681) Ensembl
MGI
TreeGrafter		 PMID:12054681 GO_REF:0000107 GO_REF:0000118 NCBI chr10:8,683,541...8,730,757
Ensembl chr10:8,684,242...8,729,268 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:10,313,782...10,340,652
Ensembl chr27:10,314,187...10,340,682 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:20018936) BHF-UCL PMID:20018936 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RPS6KA4 ribosomal protein S6 kinase A4 involved_in ISO (PMID:20018936) BHF-UCL PMID:20018936 NCBI chr18:52,708,849...52,720,561
Ensembl chr18:52,708,838...52,736,728 		JBrowse link
G RPS6KA5 ribosomal protein S6 kinase A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:61,801,185...61,962,846
Ensembl chr 8:61,802,812...61,973,259 		JBrowse link
G ST18 ST18 C2H2C-type zinc finger transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:3,971,851...4,266,642
Ensembl chr29:3,974,157...4,080,067 		JBrowse link
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (MGI:2149909|PMID:11544529) BHF-UCL PMID:11544529 MGI:2149909 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TNIP2 TNFAIP3 interacting protein 2 involved_in ISO (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chr 3:61,511,676...61,535,480 JBrowse link
G TOLLIP toll interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:45,559,385...45,578,467
Ensembl chr18:45,560,681...45,578,449 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20967881 GO_REF:0000107 RGD:5130945 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
interleukin-10-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 involved_in ISO (PMID:24994464) UniProt PMID:24994464 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL10RA interleukin 10 receptor subunit alpha involved_in ISO (PMID:16982608) UniProt PMID:16982608 NCBI chr 5:15,675,775...15,688,935
Ensembl chr 5:15,677,547...15,682,163 		JBrowse link
G IL10RB interleukin 10 receptor subunit beta involved_in ISO (PMID:16982608) UniProt PMID:16982608 NCBI chr31:28,791,541...28,815,163
Ensembl chr31:27,892,394...27,915,637 		JBrowse link
G JAK1 Janus kinase 1 involved_in ISO (PMID:7543512) UniProt PMID:7543512 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G LOC484306 leukocyte immunoglobulin-like receptor subfamily B member 3 involved_in ISO (PMID:17163451) ARUK-UCL PMID:17163451 NCBI chr 1:102,779,562...102,786,924 JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in ISO (PMID:7543512) UniProt PMID:7543512 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TYK2 tyrosine kinase 2 involved_in ISO (PMID:7543512) UniProt PMID:7543512 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
interleukin-11-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL11 interleukin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:102,311,960...102,319,102
Ensembl chr 1:102,316,105...102,318,653 		JBrowse link
G IL11RA interleukin 11 receptor subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,324,915...51,341,981 JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
interleukin-12-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL12A interleukin 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:26,125,529...26,133,546
Ensembl chr34:26,124,770...26,133,550 		JBrowse link
G IL12B interleukin 12B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:51,178,637...51,194,606
Ensembl chr 4:51,183,568...51,193,228 		JBrowse link
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,885,410...44,908,139
Ensembl chr20:44,885,337...44,904,538 		JBrowse link
G IL12RB2 interleukin 12 receptor subunit beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:43,197,034...43,269,571
Ensembl chr 5:43,197,034...43,257,594 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539 		JBrowse link
G STAT4 signal transducer and activator of transcription 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,566,563...1,685,378
Ensembl chr37:1,566,585...1,829,894 		JBrowse link
G TYK2 tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
interleukin-13-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300LF CD300 molecule like family member f involved_in ISO (MGI:5660125|PMID:26124135) UniProt PMID:26124135 MGI:5660125 NCBI chr 9:5,700,915...5,714,868 JBrowse link
interleukin-15-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD4 CD4 molecule involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr27:38,204,003...38,250,771
Ensembl chr27:38,204,003...38,250,771 		JBrowse link
G IL15 interleukin 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,339,607...1,364,762
Ensembl chr19:1,339,967...1,364,762 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 2:29,981,385...30,034,364
Ensembl chr 2:29,981,234...30,038,945 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK3 Janus kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G MFAP3 microfibril associated protein 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:55,609,857...55,629,303
Ensembl chr 4:55,613,386...55,617,446 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:13,337,285...13,996,218
Ensembl chr24:13,322,296...13,995,539 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,747,303...2,772,574
Ensembl chr38:2,747,297...2,772,587 		JBrowse link
G IL17A interleukin 17A involved_in ISO (PMID:21350122) UniProt PMID:21350122 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G IL17F interleukin 17F involved_in ISO (PMID:21350122) UniProt PMID:21350122 NCBI chr12:19,904,283...19,908,497
Ensembl chr12:19,904,126...19,908,619 		JBrowse link
G IL17RA interleukin 17 receptor A involved_in ISO (PMID:33723527)
(MGI:6694386|PMID:33723527), (PMID:19825828), (PMID:28561022)
(PMID:21350122)		 UniProt PMID:19825828 PMID:21350122 PMID:28561022 PMID:33723527 MGI:6694386 NCBI chr27:44,798,960...44,812,287
Ensembl chr27:44,791,066...44,811,064 		JBrowse link
G NOTCH1 notch receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277 		JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 involved_in ISO (PMID:21822258) MGI PMID:21822258 NCBI chr 9:32,692,517...32,696,325
Ensembl chr 9:32,694,073...32,696,285 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,688,071...48,713,936
Ensembl chr 9:48,689,331...48,703,633 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,029,861...68,070,901
Ensembl chr12:68,030,197...68,058,518 		JBrowse link
G TRAF5 TNF receptor associated factor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:9,812,019...9,831,955
Ensembl chr 7:9,812,132...9,831,955 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in ISO (PMID:23042150) MGI PMID:23042150 NCBI chr31:12,555,614...12,692,765
Ensembl chr31:12,555,595...12,691,694 		JBrowse link
interleukin-17A-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL17A interleukin 17A involved_in ISO (PMID:12297109) UniProt PMID:12297109 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G IL17RA interleukin 17 receptor A involved_in ISO (PMID:9367539) UniProt PMID:9367539 NCBI chr27:44,798,960...44,812,287
Ensembl chr27:44,791,066...44,811,064 		JBrowse link
G IL17RC interleukin 17 receptor C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,342,622...8,355,996
Ensembl chr20:8,334,345...8,355,387 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,029,861...68,070,901
Ensembl chr12:68,030,197...68,058,518 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G IL18 interleukin 18 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:15843532) UniProt
MGI
Ensembl		 PMID:15843532 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:20,972,742...20,995,327
Ensembl chr 5:20,972,871...20,995,348 		JBrowse link
G IL18R1 interleukin 18 receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10227969) Ensembl
TreeGrafter
MGI		 PMID:10227969 GO_REF:0000107 GO_REF:0000118 NCBI chr10:40,614,336...40,653,300
Ensembl chr10:40,615,312...40,653,454 		JBrowse link
G IL18RAP interleukin 18 receptor accessory protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15843532) Ensembl
TreeGrafter
MGI		 PMID:15843532 GO_REF:0000107 GO_REF:0000118 NCBI chr10:40,578,503...40,605,800
Ensembl chr10:40,581,096...40,605,766 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:25,798,877...25,819,422
Ensembl chr10:25,798,938...25,817,746 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
interleukin-2-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2 interleukin 2 involved_in ISO (PMID:22844114) UniProt PMID:22844114 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha involved_in IEA GOC GO_REF:0000108 NCBI chr 2:29,892,130...29,948,926
Ensembl chr 2:29,894,125...29,944,643 		JBrowse link
G IL2RB interleukin 2 receptor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,370,797...27,388,775
Ensembl chr10:27,370,797...27,388,775 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma involved_in ISO (PMID:7568005) UniProt PMID:7568005 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK3 Janus kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
interleukin-22-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNAR2 interferon alpha and beta receptor subunit 2 involved_in IEA GOC GO_REF:0000108 NCBI chr31:27,860,094...27,891,361 JBrowse link
G IL22RA1 interleukin 22 receptor subunit alpha 1 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:75,454,087...75,475,211
Ensembl chr 2:75,454,164...75,474,218 		JBrowse link
G IL22RA2 interleukin 22 receptor subunit alpha 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:29,611,096...29,631,811
Ensembl chr 1:29,611,722...29,631,473 		JBrowse link
interleukin-23-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL12RB1 interleukin 12 receptor subunit beta 1 involved_in IEA GOC GO_REF:0000108 NCBI chr20:44,885,410...44,908,139
Ensembl chr20:44,885,337...44,904,538 		JBrowse link
G IL23R interleukin 23 receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 5:43,307,422...43,369,806
Ensembl chr 5:43,308,982...43,368,474 		JBrowse link
G MIR301A microRNA mir-301a acts_upstream_of_or_within ISO (PMID:22517757) MGI PMID:22517757 NCBI chr 9:33,724,572...33,724,655
Ensembl chr 9:33,724,571...33,724,655 		JBrowse link
interleukin-27-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL27RA interleukin 27 receptor subunit alpha involved_in IEA GOC GO_REF:0000108 NCBI chr20:48,456,766...48,475,414
Ensembl chr20:48,457,134...48,472,450 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G LOC477518 oligoadenylate synthetase-like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,855,386...16,869,102
Ensembl chr26:16,855,386...16,869,102 		JBrowse link
G MX1 MX dynamin like GTPase 1 involved_in ISO (PMID:32270034) ARUK-UCL PMID:32270034 NCBI chr31:35,898,206...35,929,802
Ensembl chr31:35,860,590...35,951,350 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,385,393...10,396,734
Ensembl chr26:10,385,447...10,396,733 		JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,431,881...10,450,085
Ensembl chr26:10,432,042...10,449,009 		JBrowse link
G OASL 2'-5'-oligoadenylate synthetase like involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:16,837,376...16,850,388
Ensembl chr26:16,837,376...16,850,388 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
interleukin-3-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF2RB colony stimulating factor 2 receptor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,541,645...27,566,907
Ensembl chr10:27,541,647...27,567,278 		JBrowse link
G FCER1G Fc epsilon receptor Ig involved_in ISO (MGI:3831068|PMID:19098920) UniProt PMID:19098920 MGI:3831068 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940 		JBrowse link
G IL3 interleukin 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:35281014)
(PMID:19109256)		 UniProt
MGI		 PMID:19109256 PMID:35281014 NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668 		JBrowse link
G IL3RA interleukin 3 receptor subunit alpha involved_in
acts_upstream_of_or_within		 ISO (PMID:8649415)
(PMID:19109256)		 UniProt
MGI		 PMID:8649415 PMID:19109256 NCBI chr  X:894,590...912,213
Ensembl chr  X:894,552...911,556 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
interleukin-33-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RAP interleukin 1 receptor accessory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:22,547,422...22,628,628
Ensembl chr34:22,546,899...22,623,544 		JBrowse link
G IL1RL1 interleukin 1 receptor like 1 involved_in ISO (PMID:16286016) UniProt PMID:16286016 NCBI chr10:40,658,191...40,732,097
Ensembl chr10:40,659,041...40,677,357 		JBrowse link
G IL33 interleukin 33 involved_in ISO (MGI:6414704|PMID:26936882) ARUK-UCL PMID:26936882 MGI:6414704 NCBI chr11:27,219,878...27,256,723
Ensembl chr11:27,219,878...27,256,721 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IRAK4 interleukin 1 receptor associated kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:10,313,782...10,340,652
Ensembl chr27:10,314,187...10,340,682 		JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:49,669,849...49,740,039
Ensembl chr12:49,672,389...49,739,850 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
interleukin-34-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL34 interleukin 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:76,601,310...76,612,665
Ensembl chr 5:76,555,214...76,625,012 		JBrowse link
interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL4 interleukin 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G IL4R interleukin 4 receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK3 Janus kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G STAT6 signal transducer and activator of transcription 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,232,515...1,247,011
Ensembl chr10:1,233,691...1,247,075 		JBrowse link
interleukin-5-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF2RB colony stimulating factor 2 receptor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:27,541,645...27,566,907
Ensembl chr10:27,541,647...27,567,278 		JBrowse link
G IL5 interleukin 5 involved_in ISO (PMID:33099778) UniProt PMID:33099778 NCBI chr11:20,825,469...20,827,269
Ensembl chr11:20,825,469...20,827,269 		JBrowse link
G IL5RA interleukin 5 receptor subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:14,309,805...14,349,433
Ensembl chr20:14,314,227...14,343,793 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPA CCAAT enhancer binding protein alpha involved_in ISO (PMID:24429361) ARUK-UCL PMID:24429361 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CTR9 CTR9 homolog, Paf1/RNA polymerase II complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:33,915,804...33,949,597
Ensembl chr21:33,915,772...33,949,103 		JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999 		JBrowse link
G GAB1 GRB2 associated binding protein 1 acts_upstream_of_or_within ISO (PMID:10779359) MGI PMID:10779359 NCBI chr19:10,269...117,808
Ensembl chr19:12,616...156,694 		JBrowse link
G IL6 interleukin 6 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:1312474) UniProt
MGI
Ensembl		 PMID:1312474 GO_REF:0000024 GO_REF:0000107 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G IL6R interleukin 6 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1312474) Ensembl
MGI
TreeGrafter		 PMID:1312474 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:42,877,731...42,920,149
Ensembl chr 7:42,880,885...42,920,090 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer involved_in ISO
IEA		 RGD
GOC
Ensembl		 PMID:18280048 GO_REF:0000107 GO_REF:0000108 RGD:5686900 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G SMAD4 SMAD family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:23,875,989...23,930,027
Ensembl chr 1:23,882,139...23,969,405 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G ST18 ST18 C2H2C-type zinc finger transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:3,971,851...4,266,642
Ensembl chr29:3,974,157...4,080,067 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TUT4 terminal uridylyl transferase 4 involved_in ISO (MGI:4365679|PMID:19701194) UniProt PMID:19701194 MGI:4365679 NCBI chr15:8,832,208...8,958,136
Ensembl chr15:8,832,199...9,047,152 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:29,394,760...29,495,977
Ensembl chr 5:29,394,541...29,496,251 		JBrowse link
interleukin-7-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2RG interleukin 2 receptor subunit gamma involved_in ISO (PMID:8128231) UniProt PMID:8128231 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G IL7 interleukin 7 involved_in ISO (PMID:25870237) UniProt PMID:25870237 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737 		JBrowse link
G IL7R interleukin 7 receptor involved_in ISO (PMID:8128231) UniProt PMID:8128231 NCBI chr 4:72,633,528...72,668,242
Ensembl chr 4:72,636,325...72,668,300 		JBrowse link
G TSLP thymic stromal lymphopoietin involved_in ISO (PMID:11480573) UniProt PMID:11480573 NCBI chr 3:1,502,469...1,507,696
Ensembl chr 3:1,503,188...1,507,696 		JBrowse link
interleukin-8-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCR2 C-X-C motif chemokine receptor 2 involved_in ISO (PMID:10820279) UniProt PMID:10820279 NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247 		JBrowse link
interleukin-9-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL2RG interleukin 2 receptor subunit gamma involved_in ISO (PMID:18829468) UniProt PMID:18829468 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK3 Janus kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,051,135...45,068,445
Ensembl chr20:45,050,526...45,072,805 		JBrowse link
G LOC611642 interleukin-9 receptor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6506914|PMID:30082831) GOC
GOC		 PMID:30082831 GO_REF:0000108 MGI:6506914 NCBI chr 6:40,425,072...40,437,917 JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
Kit signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in IEA
IBA
ISS		 Ensembl
GO_Central
TreeGrafter
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 acts_upstream_of ISO (PMID:16533754) MGI PMID:16533754 NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547 		JBrowse link
leptin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOR1 adiponectin receptor 1 ISO RGD PMID:18394428 RGD:2317907 NCBI chr 7:240,035...254,287
Ensembl chr 7:240,065...282,845 		JBrowse link
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19150989) Ensembl
MGI		 PMID:19150989 GO_REF:0000107 NCBI chr30:36,058,932...36,109,206
Ensembl chr30:35,927,233...36,108,381 		JBrowse link
G BBS2 Bardet-Biedl syndrome 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19150989) Ensembl
MGI		 PMID:19150989 GO_REF:0000107 NCBI chr 2:59,650,439...59,705,728
Ensembl chr 2:59,677,216...59,705,730 		JBrowse link
G LEP leptin involved_in ISO
IEA
ISS		 RGD
Ensembl
UniProt		 PMID:9070213 PMID:9618284 GO_REF:0000024 GO_REF:0000107 RGD:2290293 RGD:2290294 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LEPR leptin receptor involved_in ISO
IEA		 RGD
Ensembl		 PMID:9070213 PMID:9618284 GO_REF:0000107 RGD:2290293 RGD:2290294 NCBI chr 5:44,684,118...44,775,626
Ensembl chr 5:44,688,109...44,775,636 		JBrowse link
G MKKS MKKS centrosomal shuttling protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19150989) Ensembl
MGI		 PMID:19150989 GO_REF:0000107 NCBI chr24:11,887,504...11,914,055
Ensembl chr24:11,898,236...11,913,740 		JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 involved_in ISO (MGI:5299282|PMID:21726645) UniProt PMID:21726645 MGI:5299282 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (MGI:4821191|PMID:20620997) UniProt PMID:20620997 MGI:4821191 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:66,439,346...66,472,897
Ensembl chr11:66,439,346...66,472,897 		JBrowse link
macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF1 colony stimulating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371 		JBrowse link
G CSF1R colony stimulating factor 1 receptor involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 4:58,980,699...59,010,683
Ensembl chr 4:58,980,788...59,010,510 		JBrowse link
G DOK1 docking protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10585470) Ensembl
MGI		 PMID:10585470 GO_REF:0000107 NCBI chr17:48,588,579...48,591,523
Ensembl chr17:48,589,023...48,591,721 		JBrowse link
macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD74 CD74 molecule involved_in ISO (MGI:4943655|PMID:19413900) BHF-UCL PMID:19413900 MGI:4943655 NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151 		JBrowse link
negative regulation of appetite by leptin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:36,058,932...36,109,206
Ensembl chr30:35,927,233...36,108,381 		JBrowse link
G BBS2 Bardet-Biedl syndrome 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,650,439...59,705,728
Ensembl chr 2:59,677,216...59,705,730 		JBrowse link
G LEP leptin involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G MKKS MKKS centrosomal shuttling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:11,887,504...11,914,055
Ensembl chr24:11,898,236...11,913,740 		JBrowse link
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR101-1 microRNA mir-101-1 involved_in ISO (PMID:27693460) BHF-UCL PMID:27693460 NCBI chr 5:45,184,774...45,184,828
Ensembl chr 5:45,184,759...45,184,841 		JBrowse link
G MIR101-2 microRNA mir-101-2 involved_in ISO (PMID:27693460) BHF-UCL PMID:27693460 NCBI chr 1:93,194,328...93,194,382
Ensembl chr 1:93,194,309...93,194,399 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:28972028) ARUK-UCL PMID:28972028 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G PADI2 peptidyl arginine deiminase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:81,116,031...81,147,889
Ensembl chr 2:81,116,140...81,145,043 		JBrowse link
G RNF113A ring finger protein 113A involved_in ISO (PMID:28978524) UniProt PMID:28978524 NCBI chr  X:91,884,757...91,885,998
Ensembl chr  X:91,884,808...91,885,854 		JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:8,082,363...8,594,623
Ensembl chr31:7,626,126...8,593,728 		JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204 		JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:88,964,707...89,311,817
Ensembl chr 3:88,966,232...89,312,955 		JBrowse link
G SLIT3 slit guidance ligand 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:42,506,680...43,099,053
Ensembl chr 4:42,508,426...43,094,714 		JBrowse link
negative regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (PMID:12388746) MGI PMID:12388746 NCBI chr14:55,458,934...55,494,563
Ensembl chr14:55,461,048...55,492,935 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21217760) Ensembl
MGI		 PMID:21217760 GO_REF:0000107 NCBI chr17:59,696,125...59,701,990
Ensembl chr17:59,696,477...59,701,744 		JBrowse link
G IL36RN interleukin 36 receptor antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:37,184,527...37,190,094
Ensembl chr17:37,184,801...37,189,018 		JBrowse link
G MIR20A microRNA mir-20a involved_in ISO (PMID:28972028) BHF-UCL PMID:28972028 NCBI chr22:42,478,462...42,478,520
Ensembl chr22:42,478,462...42,478,520 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:30106099) ARUK-UCL PMID:30106099 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR29B-1 microRNA mir-29b-1 acts_upstream_of ISO (PMID:23729669) ARUK-UCL PMID:23729669 NCBI chr14:6,184,457...6,184,521
Ensembl chr14:6,184,446...6,184,531 		JBrowse link
G MIR29B-2 microRNA mir-29b-2 acts_upstream_of ISO (PMID:23729669) ARUK-UCL PMID:23729669 NCBI chr 7:6,651,878...6,651,943
Ensembl chr 7:6,651,866...6,651,955 		JBrowse link
G PALM3 paralemmin 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:48,452,778...48,456,625
Ensembl chr20:48,452,772...48,456,397 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:4,155,876...4,282,151
Ensembl chr 7:4,137,728...4,282,124 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F ISO hepatocyte growth factor/Met signaling RGD PMID:16415345 RGD:1642742 NCBI chr15:16,590,908...16,666,673
Ensembl chr15:16,591,308...16,666,673 		JBrowse link
G SIGIRR single Ig and TIR domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,548,484...25,553,720
Ensembl chr18:25,548,637...25,553,923 		JBrowse link
negative regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1R2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 NCBI chr10:40,967,532...41,003,659
Ensembl chr10:40,896,669...41,034,113 		JBrowse link
G IL1RN interleukin 1 receptor antagonist involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329 		JBrowse link
G IL6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) BHF-UCL PMID:11159963 MGI:5795829 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G MIR21 microRNA mir-21 acts_upstream_of_or_within ISO (PMID:25327529) BHF-UCL PMID:25327529 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MIR27A microRNA mir-27a involved_in ISO (PMID:25327529) BHF-UCL PMID:25327529 NCBI chr20:48,620,556...48,620,615
Ensembl chr20:48,620,556...48,620,615 		JBrowse link
G OTUD4 OTU deubiquitinase 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr15:43,816,656...43,861,813
Ensembl chr15:43,818,196...43,861,784 		JBrowse link
negative regulation of interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR135A-1 microRNA mir-135a-1 involved_in ISO (PMID:29734196) ARUK-UCL PMID:29734196 NCBI chr20:37,461,817...37,461,903
Ensembl chr20:37,461,817...37,461,903 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:12,555,614...12,692,765
Ensembl chr31:12,555,595...12,691,694 		JBrowse link
negative regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175 		JBrowse link
negative regulation of interleukin-2-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
negative regulation of interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
negative regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL6ST interleukin 6 cytokine family signal transducer involved_in ISO (PMID:8353278) BHF-UCL PMID:8353278 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G MIR125A microRNA mir-125a acts_upstream_of_or_within ISO (PMID:30670152) ARUK-UCL PMID:30670152 NCBI chr 1:105,400,273...105,400,332
Ensembl chr 1:105,400,270...105,400,337 		JBrowse link
G MIR125B-1 microRNA mir-125b-1 involved_in ISO (PMID:26455324) ARUK-UCL PMID:26455324 NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745 		JBrowse link
G MIR125B-2 microRNA mir-125b-2 involved_in ISO (PMID:26455324) ARUK-UCL PMID:26455324 NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052 		JBrowse link
G MIR26A-1 microRNA mir-26a-1 involved_in ISO (PMID:23389848) ARUK-UCL PMID:23389848 NCBI chr23:7,747,073...7,747,133
Ensembl chr23:7,747,064...7,747,140 		JBrowse link
G MIR26A-2 microRNA mir-26a-2 involved_in ISO (PMID:23389848) ARUK-UCL PMID:23389848 NCBI chr10:1,880,513...1,880,572
Ensembl chr10:1,880,513...1,880,572 		JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:26587789)
(PMID:31886314)		 ARUK-UCL PMID:26587789 PMID:31886314 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775 		JBrowse link
G MIR99A-1 microRNA mir-99a-1 involved_in ISO (PMID:26455324) ARUK-UCL PMID:26455324 NCBI chr31:13,258,782...13,258,840
Ensembl chr31:13,258,782...13,258,840 		JBrowse link
G MIRLET7A-1 microRNA let-7a-1 involved_in ISO (PMID:19878981) ARUK-UCL PMID:19878981 NCBI chr10:20,034,319...20,034,387
Ensembl chr10:20,034,319...20,034,387 		JBrowse link
G MIRLET7A-2 microRNA let-7a-2 involved_in ISO (PMID:19878981) ARUK-UCL PMID:19878981 NCBI chr 5:12,052,786...12,052,881
Ensembl chr 5:12,052,786...12,052,881 		JBrowse link
G MIRLET7C microRNA let-7c involved_in ISO (PMID:26455324) ARUK-UCL PMID:26455324 NCBI chr31:13,259,522...13,259,588
Ensembl chr31:13,259,502...13,259,609 		JBrowse link
G MIRLET7E microRNA let-7e acts_upstream_of_or_within ISO (PMID:30670152) ARUK-UCL PMID:30670152 NCBI chr 1:105,400,740...105,400,806
Ensembl chr 1:105,400,730...105,400,816 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
negative regulation of Kit signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RABGEF1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO (PMID:16533754) MGI PMID:16533754 NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547 		JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204 		JBrowse link
negative regulation of macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:58,091,457...58,148,902
Ensembl chr13:58,091,477...58,133,711 		JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 involved_in ISO (PMID:33097708) ARUK-UCL PMID:33097708 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174 		JBrowse link
negative regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844 		JBrowse link
G APOA1 apolipoprotein A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G BIRC7 baculoviral IAP repeat containing 7 involved_in ISO (PMID:11865055) UniProt PMID:11865055 NCBI chr24:46,950,700...46,956,375
Ensembl chr24:46,952,474...46,955,495 		JBrowse link
G CCDC3 coiled-coil domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:23,477,696...23,593,107
Ensembl chr 2:23,477,696...23,591,036 		JBrowse link
G CLDN18 claudin 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22437732) Ensembl
MGI		 PMID:22437732 GO_REF:0000107 NCBI chr23:34,229,115...34,257,431
Ensembl chr23:34,228,992...34,255,650 		JBrowse link
G DICER1 dicer 1, ribonuclease III involved_in
acts_upstream_of		 IEA
ISO		 (PMID:26435691) Ensembl
ARUK-UCL		 PMID:26435691 GO_REF:0000107 NCBI chr 8:63,970,245...64,029,438
Ensembl chr 8:63,972,027...64,019,879 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,801,119...29,810,006
Ensembl chr 3:29,800,211...29,810,180 		JBrowse link
G GAS6 growth arrest specific 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875 		JBrowse link
G GPS2 G protein pathway suppressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,273,169...32,275,915
Ensembl chr 5:32,273,173...32,275,580 		JBrowse link
G H2BC11 H2B clustered histone 11 involved_in ISO (PMID:11859126) UniProt PMID:11859126 NCBI chr35:24,540,629...24,543,786 JBrowse link
G HSF4 heat shock transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:82,190,996...82,201,224
Ensembl chr 5:82,196,500...82,201,151
Ensembl chr 5:82,196,500...82,201,151 		JBrowse link
G LOC119876002 caspase recruitment domain-containing protein 8-like involved_in IEA Ensembl GO_REF:0000107
G LOC491519 caspase recruitment domain family, member 8 involved_in ISO (PMID:11821383) UniProt PMID:11821383 NCBI chr 1:107,994,215...108,025,875 JBrowse link
G MIR125B-1 microRNA mir-125b-1 acts_upstream_of ISO (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr 5:12,097,672...12,097,732
Ensembl chr 5:12,097,658...12,097,745 		JBrowse link
G MIR125B-2 microRNA mir-125b-2 acts_upstream_of ISO (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr31:13,304,980...13,305,040
Ensembl chr31:13,304,964...13,305,052 		JBrowse link
G MIR130A microRNA mir-130a acts_upstream_of ISO (PMID:26435691) ARUK-UCL PMID:26435691 NCBI chr18:38,543,618...38,543,679
Ensembl chr18:38,543,618...38,543,681 		JBrowse link
G MIR152 microRNA mir-152 involved_in ISO (PMID:24813629) BHF-UCL PMID:24813629 NCBI chr 9:24,335,161...24,335,219
Ensembl chr 9:24,335,146...24,335,225 		JBrowse link
G MIR27B microRNA mir-27b acts_upstream_of_or_within ISO (PMID:31124343) ARUK-UCL PMID:31124343 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116 		JBrowse link
G PELI3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24113711)
(PMID:23950925)		 MGI
Ensembl		 PMID:23950925 PMID:24113711 GO_REF:0000107 NCBI chr18:50,870,483...50,881,089
Ensembl chr18:50,872,426...50,879,826 		JBrowse link
G PIAS4 protein inhibitor of activated STAT 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr20:55,529,841...55,553,604
Ensembl chr20:55,524,443...55,553,525 		JBrowse link
G PPP2CB protein phosphatase 2 catalytic subunit beta acts_upstream_of
involved_in		 ISO
IEA		 (PMID:28159925) ARUK-UCL
Ensembl		 PMID:28159925 GO_REF:0000107 NCBI chr16:33,532,703...33,567,011
Ensembl chr16:33,532,958...33,566,640 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in ISO (PMID:18450452) UniProt PMID:18450452 NCBI chr 9:38,271,419...38,346,103
Ensembl chr 9:38,222,051...38,365,621 		JBrowse link
G TANK TRAF family member associated NFKB activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:6,732,507...6,826,762
Ensembl chr36:6,750,265...6,826,486 		JBrowse link
G TJP2 tight junction protein 2 acts_upstream_of_or_within ISO (PMID:22437732) MGI PMID:22437732 NCBI chr 1:88,126,134...88,251,018
Ensembl chr 1:88,126,136...88,230,654 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29415886) Ensembl
MGI		 PMID:29415886 GO_REF:0000107 NCBI chr13:18,155,765...18,183,263
Ensembl chr13:18,156,367...18,183,444 		JBrowse link
G TRAIP TRAF interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:39,430,109...39,454,437
Ensembl chr20:39,430,489...39,453,933 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,300,234...95,356,103
Ensembl chr  X:95,331,827...95,351,582 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAR adenosine deaminase RNA specific involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19060901) Ensembl
MGI		 PMID:19060901 GO_REF:0000107 NCBI chr 7:42,762,021...42,785,192
Ensembl chr 7:42,748,136...42,782,999 		JBrowse link
G CACTIN cactin, spliceosome C complex subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,803,494...55,817,467
Ensembl chr20:55,803,530...55,816,549 		JBrowse link
G CNOT7 CCR4-NOT transcription complex subunit 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:40,554,214...40,571,841
Ensembl chr16:40,555,565...40,571,720 		JBrowse link
G DCST1 DC-STAMP domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,443,787...42,457,361
Ensembl chr 7:42,428,113...42,457,062 		JBrowse link
G EIF4E2 eukaryotic translation initiation factor 4E family member 2 involved_in ISO (PMID:35878012) UniProt PMID:35878012 NCBI chr25:44,192,037...44,203,401
Ensembl chr25:44,192,038...44,214,631 		JBrowse link
G GIGYF2 GRB10 interacting GYF protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:44,317,540...44,453,761
Ensembl chr25:44,317,517...44,452,064 		JBrowse link
G ISG15 ISG15 ubiquitin like modifier involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:56,230,879...56,237,354
Ensembl chr 5:56,236,318...56,404,695 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807 		JBrowse link
G METTL3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,528,755...18,546,303
Ensembl chr15:18,528,772...18,546,531 		JBrowse link
G MIR21 microRNA mir-21 involved_in ISO (PMID:23633945) BHF-UCL PMID:23633945 NCBI chr 9:34,340,550...34,340,609
Ensembl chr 9:34,340,533...34,340,624 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,918,626...28,933,404
Ensembl chr 5:28,918,594...28,933,309 		JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) UniProt PMID:23399697 NCBI chr 2:78,394,013...78,402,032
Ensembl chr 2:78,394,040...78,425,482 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:59,279,535...59,359,327
Ensembl chr 2:59,280,390...59,338,931 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,385,393...10,396,734
Ensembl chr26:10,385,447...10,396,733 		JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,404,548...10,423,039
Ensembl chr26:10,404,414...10,423,039 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:25,623,997...25,676,336
Ensembl chr24:25,626,134...25,680,902 		JBrowse link
G SMIM30 small integral membrane protein 30 involved_in ISO (PMID:37656786) UniProt PMID:37656786 NCBI chr14:52,594,889...52,596,902
Ensembl chr14:52,595,562...52,595,741 		JBrowse link
G STAT2 signal transducer and activator of transcription 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:641,543...660,882
Ensembl chr10:642,718...658,546 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18724932) Ensembl
MGI		 PMID:18724932 GO_REF:0000107 NCBI chr20:40,624,845...40,626,840
Ensembl chr20:40,624,891...40,626,906 		JBrowse link
G TTLL12 tubulin tyrosine ligase like 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:22,367,590...22,385,167
Ensembl chr10:22,367,367...22,386,617 		JBrowse link
G USP18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) UniProt PMID:28165510 NCBI chr27:45,739,845...45,814,668 JBrowse link
G YTHDF2 YTH N6-methyladenosine RNA binding protein F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:71,760,232...71,791,420
Ensembl chr 2:71,760,312...71,792,527 		JBrowse link
G YTHDF3 YTH N6-methyladenosine RNA binding protein F3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:13,239,900...13,280,035
Ensembl chr29:13,239,966...13,277,051 		JBrowse link
negative regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARG1 arginase 1 involved_in ISO (PMID:16709924) UniProt PMID:16709924 NCBI chr12:242,717...255,736
Ensembl chr12:242,714...255,305 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11679576) UniProt PMID:11679576 NCBI chr 6:36,921,941...36,967,718
Ensembl chr 6:36,917,858...36,967,689 		JBrowse link
G OTOP1 otopetrin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,639,550...69,665,051
Ensembl chr 3:69,640,492...69,649,201 		JBrowse link
G PARP14 poly(ADP-ribose) polymerase family member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:25,763,282...25,798,284
Ensembl chr33:25,763,255...25,798,198 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:21268089) BHF-UCL PMID:21268089 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in
NOT|involved_in		 IEA
ISO		 (PMID:12138178) Ensembl
UniProt		 PMID:12138178 GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
oncostatin-M-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL6ST interleukin 6 cytokine family signal transducer involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:43,214,050...43,273,014
Ensembl chr 2:43,214,050...43,248,124 		JBrowse link
G LIFR LIF receptor subunit alpha involved_in IEA GOC
Ensembl		 GO_REF:0000107 GO_REF:0000108 NCBI chr 4:70,328,963...70,376,127
Ensembl chr 4:70,267,514...70,376,127 		JBrowse link
G OSM oncostatin M involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr26:23,421,787...23,439,332
Ensembl chr26:23,421,787...23,426,036 		JBrowse link
G OSMR oncostatin M receptor involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 4:70,016,384...70,067,098
Ensembl chr 4:70,018,022...70,055,216 		JBrowse link
positive regulation of C-C chemokine receptor CCR7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREML1 triggering receptor expressed on myeloid cells like 1 involved_in ISO (PMID:11602640) BHF-UCL PMID:11602640 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174 		JBrowse link
positive regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 acts_upstream_of ISO (PMID:17178876) BHF-UCL PMID:17178876 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha acts_upstream_of
involved_in		 ISO
IEA		 (PMID:17178876) BHF-UCL
Ensembl		 PMID:17178876 GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
positive regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXL AXL receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,699,679...112,727,434
Ensembl chr 1:112,700,365...112,726,960 		JBrowse link
G CD74 CD74 molecule involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151 		JBrowse link
G GAS6 growth arrest specific 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,975,196...61,005,869
Ensembl chr22:60,974,849...61,005,875 		JBrowse link
G IL7 interleukin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737 		JBrowse link
G PAFAH1B1 platelet activating factor acetylhydrolase 1b regulatory subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22073305) Ensembl
MGI		 PMID:22073305 GO_REF:0000107 NCBI chr 9:46,648,057...46,731,259
Ensembl chr 9:46,648,052...46,771,400 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11894097) Ensembl
MGI		 PMID:11894097 GO_REF:0000107 NCBI chr29:35,283,209...35,311,608
Ensembl chr29:35,282,072...35,311,333 		JBrowse link
G TRIM44 tripartite motif containing 44 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:32,242,830...32,351,540
Ensembl chr18:32,247,146...32,351,648 		JBrowse link
G TSLP thymic stromal lymphopoietin involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:1,502,469...1,507,696
Ensembl chr 3:1,503,188...1,507,696 		JBrowse link
positive regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1R1 interleukin 1 receptor type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23395675) Ensembl
MGI		 PMID:23395675 GO_REF:0000107 NCBI chr10:40,825,986...40,897,898
Ensembl chr10:40,827,377...40,897,596 		JBrowse link
positive regulation of interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRIM32 tripartite motif containing 32 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr11:70,453,130...70,465,030
Ensembl chr11:70,462,007...70,463,974 		JBrowse link
positive regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP4 caspase 4, apoptosis-related cysteine peptidase involved_in ISO (PMID:33377178)
(MGI:6259277|PMID:30392956)		 UniProt PMID:30392956 PMID:33377178 MGI:6259277 NCBI chr 5:27,133,778...27,147,954
Ensembl chr 5:27,132,565...27,149,736 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,433,481...25,440,703
Ensembl chr18:25,433,698...25,440,740 		JBrowse link
G TICAM2 toll like receptor adaptor molecule 2 involved_in ISO (MGI:5488868|PMID:22685567)
(PMID:22685567)		 UniProt PMID:22685567 MGI:5488868 NCBI chr11:5,312,383...5,313,099
Ensembl chr11:5,312,383...5,313,099 		JBrowse link
positive regulation of interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300LF CD300 molecule like family member f involved_in ISO (MGI:5660125|PMID:26124135) UniProt PMID:26124135 MGI:5660125 NCBI chr 9:5,700,915...5,714,868 JBrowse link
G PARP14 poly(ADP-ribose) polymerase family member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:25,763,282...25,798,284
Ensembl chr33:25,763,255...25,798,198 		JBrowse link
positive regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QTNF4 C1q and TNF related 4 involved_in ISO (PMID:21658842) UniProt PMID:21658842 NCBI chr18:42,060,880...42,065,411 JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:11060035) UniProt PMID:11060035 NCBI chr 6:56,473,032...56,484,422
Ensembl chr 6:56,256,305...56,484,422 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883 		JBrowse link
positive regulation of macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF1 colony stimulating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,028,454...42,047,028
Ensembl chr 6:42,034,149...42,049,371 		JBrowse link
positive regulation of macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD74 CD74 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:58,689,745...58,698,421
Ensembl chr 4:58,689,752...58,698,151 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 involved_in ISO (PMID:19665027) ARUK-UCL PMID:19665027 NCBI chr19:38,874,650...38,877,740
Ensembl chr19:38,874,145...38,877,740 		JBrowse link
positive regulation of prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor acts_upstream_of_or_within ISO (PMID:23071095) MGI PMID:23071095 NCBI chr 4:39,308,429...39,366,031
Ensembl chr 4:39,313,512...39,365,953 		JBrowse link
positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM17 ADAM metallopeptidase domain 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731 		JBrowse link
G CASP4 caspase 4, apoptosis-related cysteine peptidase involved_in ISO (PMID:16920334) UniProt PMID:16920334 NCBI chr 5:27,133,778...27,147,954
Ensembl chr 5:27,132,565...27,149,736 		JBrowse link
G CPNE1 copine 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:24,554,636...24,589,748
Ensembl chr24:24,554,636...24,589,731 		JBrowse link
G HSP70 heat shock protein 70 involved_in ISO (PMID:24790089) UniProt PMID:24790089 NCBI chr12:1,285,282...1,287,670 JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) ARUK-UCL PMID:22733818 MGI:6391873 NCBI chr 2:70,188,382...70,215,361
Ensembl chr 2:70,152,739...70,333,073 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:29,036,381...29,047,180
Ensembl chr 5:29,035,820...29,046,808 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G RBM12 RNA binding motif protein 12 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:24,577,335...24,589,731
Ensembl chr24:24,554,636...24,589,731 		JBrowse link
G RIPK1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:6271183|PMID:30439713) ARUK-UCL PMID:30439713 MGI:6271183 NCBI chr35:3,367,796...3,407,631
Ensembl chr35:3,263,226...3,405,883 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,688,071...48,713,936
Ensembl chr 9:48,689,331...48,703,633 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20054338) Ensembl
MGI		 PMID:20054338 GO_REF:0000107 NCBI chr11:70,453,130...70,465,030
Ensembl chr11:70,462,007...70,463,974 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:72,713,035...72,780,199
Ensembl chr 3:72,717,236...72,780,210 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FADD Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:48,087,447...48,094,497 JBrowse link
G IKBKE inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,747,303...2,772,574
Ensembl chr38:2,747,297...2,772,587 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17618271) Ensembl
MGI		 PMID:17618271 GO_REF:0000107 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065 		JBrowse link
G IRF7 interferon regulatory factor 7 acts_upstream_of_or_within ISO (PMID:17618271) MGI PMID:17618271
G LSM14A LSM14A mRNA processing body assembly factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22745163) Ensembl
MGI		 PMID:22745163 GO_REF:0000107 NCBI chr 1:118,061,854...118,117,493
Ensembl chr 1:118,063,512...118,117,478 		JBrowse link
G MAVS mitochondrial antiviral signaling protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807 		JBrowse link
G MMP12 matrix metallopeptidase 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,918,626...28,933,404
Ensembl chr 5:28,918,594...28,933,309 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,279,535...59,359,327
Ensembl chr 2:59,280,390...59,338,931 		JBrowse link
G RBM47 RNA binding motif protein 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:71,985,725...72,135,271
Ensembl chr 3:71,985,831...72,132,918 		JBrowse link
G RNF185 ring finger protein 185 involved_in ISO (PMID:28273161) UniProt PMID:28273161 NCBI chr26:24,146,172...24,177,747
Ensembl chr26:24,146,005...24,240,653 		JBrowse link
G STING1 stimulator of interferon response cGAMP interactor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,783,947...34,792,204
Ensembl chr 2:34,784,232...34,789,072 		JBrowse link
G TBK1 TANK binding kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:7,169,664...7,208,890
Ensembl chr10:7,168,007...7,208,899 		JBrowse link
G TRIM41 tripartite motif containing 41 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:414,725...426,074
Ensembl chr11:415,764...425,656 		JBrowse link
G TRIM56 tripartite motif containing 56 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:8,744,970...8,752,896
Ensembl chr 6:8,749,438...8,751,753 		JBrowse link
G TRIM6 tripartite motif containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:28,595,887...28,611,562
Ensembl chr21:28,595,448...28,611,124 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:72,713,035...72,780,199
Ensembl chr 3:72,717,236...72,780,210 		JBrowse link
G USP27X ubiquitin specific peptidase 27 X-linked involved_in ISO (PMID:31534008) UniProt PMID:31534008 NCBI chr  X:42,645,534...42,648,801 JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17618271) InterPro
MGI
TreeGrafter		 PMID:17618271 GO_REF:0000002 GO_REF:0000118 NCBI chr24:42,583,674...42,589,857
Ensembl chr24:42,584,083...42,589,753 		JBrowse link
positive regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPX hemopexin acts_upstream_of_or_within ISO (PMID:18641331) MGI PMID:18641331 NCBI chr21:29,749,913...29,759,176
Ensembl chr21:29,719,589...29,759,046 		JBrowse link
G LOC481473 immunity-related GTPase family M protein involved_in ISO (PMID:16888103) UniProt PMID:16888103 NCBI chr11:793,416...795,373
Ensembl chr11:793,424...794,617 		JBrowse link
G LOC606863 immunity-related GTPase family M protein-like involved_in ISO (MGI:3656111|PMID:16888103) UniProt PMID:16888103 MGI:3656111 NCBI chr11:506,981...523,338
Ensembl chr11:509,636...510,829 		JBrowse link
G MED1 mediator complex subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18339625) Ensembl
MGI		 PMID:18339625 GO_REF:0000107 NCBI chr 9:22,989,257...23,019,350
Ensembl chr 9:22,989,301...23,019,349 		JBrowse link
G NLRC5 NLR family CARD domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:59,279,535...59,359,327
Ensembl chr 2:59,280,390...59,338,931 		JBrowse link
G PARP9 poly(ADP-ribose) polymerase family member 9 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr33:25,643,439...25,676,979
Ensembl chr33:25,643,883...25,677,462 		JBrowse link
G TXK TXK tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:43,911,881...43,977,499
Ensembl chr13:43,914,534...43,976,655 		JBrowse link
prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824 		JBrowse link
G PRLR prolactin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 4:73,147,919...73,280,970
Ensembl chr 4:73,110,858...73,273,916 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD24 CD24 molecule involved_in ISO (MGI:3614932|PMID:16390867) UniProt PMID:16390867 MGI:3614932 NCBI chr12:64,239,957...64,245,114 JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IRAK2 interleukin 1 receptor associated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,133,987...8,197,009
Ensembl chr20:8,134,970...8,196,910 		JBrowse link
regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VRK2 VRK serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:58,432,144...58,544,189
Ensembl chr10:58,431,978...58,544,189 		JBrowse link
G ZBP1 Z-DNA binding protein 1 involved_in ISO (MGI:6394181|PMID:31630209) UniProt PMID:31630209 MGI:6394181 NCBI chr24:42,583,674...42,589,857
Ensembl chr24:42,584,083...42,589,753 		JBrowse link
regulation of macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPT1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20060382) Ensembl
MGI		 PMID:20060382 GO_REF:0000107 NCBI chr13:8,068,920...8,312,090
Ensembl chr13:8,048,205...8,311,618 		JBrowse link
regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYLD CYLD lysine 63 deubiquitinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175 		JBrowse link
G EXT1 exostosin glycosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29415886) Ensembl
MGI		 PMID:29415886 GO_REF:0000107 NCBI chr13:17,172,497...17,457,084
Ensembl chr13:17,172,705...17,456,469 		JBrowse link
G HIPK1 homeodomain interacting protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,732,079...51,783,534
Ensembl chr17:51,732,016...51,781,063 		JBrowse link
G LOC119877641 NF-kappa-B inhibitor-interacting Ras-like protein 2 involved_in IEA Ensembl GO_REF:0000107
G NKIRAS1 NFKB inhibitor interacting Ras like 1 acts_upstream_of_or_within ISO (PMID:25220458) MGI PMID:25220458 NCBI chr23:19,829,764...19,861,462
Ensembl chr23:19,830,124...19,861,424 		JBrowse link
G NKIRAS2 NFKB inhibitor interacting Ras like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25220458) Ensembl
MGI		 PMID:25220458 GO_REF:0000107 NCBI chr 9:20,851,014...20,854,953
Ensembl chr 9:20,852,103...20,854,892 		JBrowse link
G OTULIN OTU deubiquitinase with linear linkage specificity involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr34:119,307...159,419
Ensembl chr34:122,274...159,394 		JBrowse link
G PIAS3 protein inhibitor of activated STAT 3 acts_upstream_of_or_within ISO (PMID:17442941) MGI PMID:17442941 NCBI chr17:58,650,791...58,660,755
Ensembl chr17:58,571,694...58,660,663 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G SHARPIN SHANK associated RH domain interactor involved_in ISO (PMID:21455173)
(MGI:4947438|PMID:21455180), (MGI:4947439|PMID:21455173)		 UniProt PMID:21455173 PMID:21455180 MGI:4947438 MGI:4947439 NCBI chr13:37,594,155...37,598,510
Ensembl chr13:37,594,203...37,599,456 		JBrowse link
G SPATA2 spermatogenesis associated 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:36,443,856...36,454,264
Ensembl chr24:36,445,870...36,448,585 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A acts_upstream_of_or_within ISO (PMID:25220458) MGI PMID:25220458 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282 		JBrowse link
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16280321) MGI
Ensembl		 PMID:16280321 GO_REF:0000107 NCBI chr20:50,727,702...50,738,197
Ensembl chr20:50,727,749...50,736,269 		JBrowse link
regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16280321) MGI
Ensembl		 PMID:16280321 GO_REF:0000107 NCBI chr20:50,727,702...50,738,197
Ensembl chr20:50,727,749...50,736,269 		JBrowse link
thrombopoietin-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CIB1 calcium and integrin binding 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,184,713...53,209,195
Ensembl chr 3:53,184,714...53,188,224 		JBrowse link
G MPL MPL proto-oncogene, thrombopoietin receptor involved_in IEA GOC
TreeGrafter		 GO_REF:0000108 GO_REF:0000118 NCBI chr15:16,815,102...16,825,321
Ensembl chr15:16,815,294...16,825,350 		JBrowse link
G RBM15 RNA binding motif protein 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:41,645,765...41,653,621
Ensembl chr 6:41,645,769...41,653,799 		JBrowse link
G SH2B3 SH2B adaptor protein 3 acts_upstream_of_or_within_negative_effect
involved_in
acts_upstream_of_negative_effect		 ISO
IEA		 (PMID:20404132)
(MGI:5905608|PMID:27430239)		 ARUK-UCL
Ensembl
BHF-UCL		 PMID:20404132 PMID:27430239 GO_REF:0000107 MGI:5905608 NCBI chr26:9,033,851...9,073,095
Ensembl chr26:9,005,281...9,070,204 		JBrowse link
G THPO thrombopoietin involved_in ISS
IBA
IEA		 UniProt
GO_Central
TreeGrafter
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr34:17,245,006...17,255,250
Ensembl chr34:17,247,731...17,253,033 		JBrowse link
tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN4 actinin alpha 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:114,354,993...114,427,997
Ensembl chr 1:114,309,693...114,427,991 		JBrowse link
G ADAM17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr17:6,589,874...6,638,788
Ensembl chr17:6,589,878...6,638,731 		JBrowse link
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 7:41,835,322...41,850,488
Ensembl chr 7:41,812,353...41,850,488 		JBrowse link
G CARD14 caspase recruitment domain family member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:1,547,645...1,571,567
Ensembl chr 9:1,547,686...1,573,581 		JBrowse link
G CD70 CD70 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr20:53,639,315...53,642,687
Ensembl chr20:53,639,436...53,642,319 		JBrowse link
G CHUK component of inhibitor of nuclear factor kappa B kinase complex involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:12,964,670...13,001,557
Ensembl chr28:12,965,479...13,001,512 		JBrowse link
G COMMD7 COMM domain containing 7 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:22,035,590...22,057,799
Ensembl chr24:22,035,990...22,079,583 		JBrowse link
G EIF5A eukaryotic translation initiation factor 5A involved_in ISO (PMID:17187778) UniProt PMID:17187778 NCBI chr 5:32,268,103...32,272,970 JBrowse link
G FAS Fas cell surface death receptor involved_in IEA GOC GO_REF:0000108 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FOXO3 forkhead box O3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,552,455...65,673,467
Ensembl chr12:65,552,310...65,670,198 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:23,359,551...23,419,114
Ensembl chr16:23,359,813...23,419,075 		JBrowse link
G ILK integrin linked kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,911,326...29,917,972
Ensembl chr21:29,911,364...29,917,974 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G KRT18 keratin 18 acts_upstream_of_or_within ISO (PMID:10747083) MGI PMID:10747083 NCBI chr27:2,189,269...2,193,368
Ensembl chr27:2,189,269...2,193,368 		JBrowse link
G KRT8 keratin 8 acts_upstream_of_or_within ISO (PMID:10747083) MGI PMID:10747083 NCBI chr27:2,221,608...2,229,343 JBrowse link
G LGALS7B galectin 7B involved_in IEA Ensembl GO_REF:0000107
G LIMS1 LIM zinc finger domain containing 1 involved_in ISO (PMID:21343177) CAFA PMID:21343177 NCBI chr10:35,192,582...35,339,100 JBrowse link
G LOC100683370 thymosin beta-4 acts_upstream_of_or_within_positive_effect ISO (PMID:21343177) CAFA PMID:21343177 NCBI chr 1:21,127,694...21,128,346 JBrowse link
G MIR34A microRNA mir-34a involved_in ISO (PMID:26949937) ARUK-UCL PMID:26949937 NCBI chr 5:62,485,832...62,485,897
Ensembl chr 5:62,485,832...62,485,897 		JBrowse link
G NFKBIA NFKB inhibitor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:14,100,203...14,103,453
Ensembl chr 8:14,100,671...14,103,433 		JBrowse link
G NSMAF neutral sphingomyelinase activation associated factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:9,371,111...9,427,781
Ensembl chr29:9,371,446...9,428,149 		JBrowse link
G PHF19 PHD finger protein 19 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:73,895,104...73,911,030 JBrowse link
G PLVAP plasmalemma vesicle associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,405,295...45,417,093
Ensembl chr20:45,351,091...45,416,477 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:30,137,546...30,264,221
Ensembl chr25:30,138,209...30,264,133 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:17,049,352...17,051,348
Ensembl chr 6:17,049,705...17,051,240 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RRAGA Ras related GTP binding A involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:38,886,990...38,888,634
Ensembl chr11:38,886,397...38,888,184 		JBrowse link
G ST18 ST18 C2H2C-type zinc finger transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:3,971,851...4,266,642
Ensembl chr29:3,974,157...4,080,067 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G TIFA TRAF interacting protein with forkhead associated domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:32,125,870...32,135,159
Ensembl chr32:32,126,634...32,127,191 		JBrowse link
G TNF tumor necrosis factor involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:3898078) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:3898078 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425 		JBrowse link
G TNFRSF11A TNF receptor superfamily member 11a involved_in IEA Ensembl
GOC		 GO_REF:0000107 GO_REF:0000108 NCBI chr 1:14,504,595...14,555,956
Ensembl chr 1:14,503,033...14,556,041 		JBrowse link
G TNFRSF13C TNF receptor superfamily member 13C involved_in IEA InterPro GO_REF:0000002 NCBI chr10:23,430,960...23,434,972
Ensembl chr10:23,433,052...23,438,946 		JBrowse link
G TNFRSF17 TNF receptor superfamily member 17 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:30,842,269...30,846,124
Ensembl chr 6:30,841,152...30,845,905 		JBrowse link
G TNFRSF18 TNF receptor superfamily member 18 involved_in IEA GOC GO_REF:0000108 NCBI chr 5:56,394,559...56,397,502
Ensembl chr 5:56,394,659...56,397,741 		JBrowse link
G TNFRSF1A TNF receptor superfamily member 1A involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:2152007|PMID:11588035) RGD
GOC
GOC
InterPro		 PMID:11588035 PMID:20967881 GO_REF:0000002 GO_REF:0000108 MGI:2152007 RGD:5130945 NCBI chr27:38,641,837...38,654,693
Ensembl chr27:38,638,753...38,700,282 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in IEA GOC GO_REF:0000108 NCBI chr 2:84,140,179...84,151,219
Ensembl chr 2:84,141,911...84,157,191 		JBrowse link
G TNFRSF4 TNF receptor superfamily member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2683815|PMID:14635034) GOC
GOC		 PMID:14635034 GO_REF:0000108 MGI:2683815 NCBI chr 5:56,401,410...56,404,410
Ensembl chr 5:56,401,384...56,404,761 		JBrowse link
G TNFSF11 TNF superfamily member 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17442941), (PMID:18269914), (PMID:22437732) Ensembl
MGI		 PMID:17442941 PMID:18269914 PMID:22437732 GO_REF:0000107 NCBI chr22:8,226,931...8,257,926
Ensembl chr22:8,227,555...8,258,645 		JBrowse link
G TNFSF13B TNF superfamily member 13b involved_in ISO (PMID:18624351) MGI PMID:18624351 NCBI chr22:57,036,307...57,069,053
Ensembl chr22:57,036,292...57,068,320 		JBrowse link
G TNFSF18 TNF superfamily member 18 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 7:25,983,064...25,994,605
Ensembl chr 7:25,963,719...25,992,801 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TRADD TNFRSF1A associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:82,200,430...82,211,430
Ensembl chr 5:82,206,111...82,210,963 		JBrowse link
G TRAF2 TNF receptor associated factor 2 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:10713108 PMID:20967881 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:2298798 RGD:5130945 NCBI chr 9:48,688,071...48,713,936
Ensembl chr 9:48,689,331...48,703,633 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:70,739,389...70,794,448
Ensembl chr 8:70,739,417...70,790,645 		JBrowse link
G TRAF3IP2 TRAF3 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,029,861...68,070,901
Ensembl chr12:68,030,197...68,058,518 		JBrowse link
G TRAF4 TNF receptor associated factor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:42,933,638...42,940,033
Ensembl chr 9:42,933,750...42,939,520 		JBrowse link
G TRAF5 TNF receptor associated factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:9,812,019...9,831,955
Ensembl chr 7:9,812,132...9,831,955 		JBrowse link
G TRAF6 TNF receptor associated factor 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:31,674,242...31,689,160
Ensembl chr18:31,675,391...31,688,641 		JBrowse link
G TXNDC17 thioredoxin domain containing 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:30,701,673...30,703,742
Ensembl chr 5:30,701,700...30,703,739 		JBrowse link
G UMOD uromodulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28990932) Ensembl
MGI		 PMID:28990932 GO_REF:0000107 NCBI chr 6:24,991,459...25,006,735
Ensembl chr 6:24,991,459...25,006,735 		JBrowse link
type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HDAC4 histone deacetylase 4 involved_in ISO (PMID:31127039) UniProt PMID:31127039 NCBI chr25:49,318,621...49,545,314
Ensembl chr25:49,317,349...49,453,478 		JBrowse link
G IFIH1 interferon induced with helicase C domain 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28031478) Ensembl
MGI		 PMID:28031478 GO_REF:0000107 NCBI chr36:7,668,925...7,727,040
Ensembl chr36:7,649,727...8,261,048 		JBrowse link
G IFNAR1 interferon alpha and beta receptor subunit 1 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr31:28,854,765...28,876,399 JBrowse link
G IFNAR2 interferon alpha and beta receptor subunit 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr31:27,860,094...27,891,361 JBrowse link
G IFNB1 interferon beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:40,668,295...40,668,855
Ensembl chr11:40,668,295...40,668,855 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576 		JBrowse link
G IRF3 interferon regulatory factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,875,016...106,879,065
Ensembl chr 1:106,875,118...106,879,065 		JBrowse link
G IRF7 interferon regulatory factor 7 involved_in ISO (MGI:5792628|PMID:27129230) UniProt PMID:27129230 MGI:5792628
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G LOC119864110 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC119864111 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC119864112 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC119864113 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC119864114 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118
G LOC475935 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:25,484,731...25,485,927 JBrowse link
G LOC475936 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:25,486,525...25,488,376 JBrowse link
G LOC483396 interferon-induced transmembrane protein 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:25,461,913...25,463,021 JBrowse link
G LOC483397 interferon-induced transmembrane protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:25,494,018...25,495,114 JBrowse link
G LOC606890 interferon-induced transmembrane protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr18:25,459,466...25,461,399 JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G OAS1 2'-5'-oligoadenylate synthetase 1 involved_in ISO (PMID:28640813) ARUK-UCL PMID:28640813 NCBI chr26:10,385,393...10,396,734
Ensembl chr26:10,385,447...10,396,733 		JBrowse link
G OAS2 2'-5'-oligoadenylate synthetase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:10,431,881...10,450,085
Ensembl chr26:10,432,042...10,449,009 		JBrowse link
G SIN3A SIN3 transcription regulator family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:38,231,844...38,306,665
Ensembl chr30:38,232,680...38,382,635 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G STAT2 signal transducer and activator of transcription 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:641,543...660,882
Ensembl chr10:642,718...658,546 		JBrowse link
G TREX1 three prime repair exonuclease 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28351661) Ensembl
MGI		 PMID:28351661 GO_REF:0000107 NCBI chr20:40,624,845...40,626,840
Ensembl chr20:40,624,891...40,626,906 		JBrowse link
G TRIM65 tripartite motif containing 65 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28031478) Ensembl
MGI		 PMID:28031478 GO_REF:0000107 NCBI chr 9:4,713,535...4,720,268
Ensembl chr 9:4,714,086...4,718,592 		JBrowse link
G TYK2 tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HPX hemopexin acts_upstream_of ISO (PMID:18641331) MGI PMID:18641331 NCBI chr21:29,749,913...29,759,176
Ensembl chr21:29,719,589...29,759,046 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IFNGR1 interferon gamma receptor 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:29,646,776...29,669,669
Ensembl chr 1:29,647,552...29,669,578 		JBrowse link
G IRF1 interferon regulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,773,801...20,781,106
Ensembl chr11:20,760,120...20,781,608 		JBrowse link
G JAK1 Janus kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:45,251,653...45,408,571
Ensembl chr 5:45,251,653...45,408,571 		JBrowse link
G JAK2 Janus kinase 2 involved_in ISO PMID:11536325 BHF-UCL PMID:11536325 RGD:8553830 NCBI chr 1:93,321,055...93,438,898
Ensembl chr 1:93,142,635...93,435,997 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G TP53 tumor protein p53 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109 		JBrowse link
G TYK2 tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,747,145...50,770,008
Ensembl chr20:50,748,329...50,769,216 		JBrowse link
type III interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,406,866...10,411,698
Ensembl chr10:10,406,867...10,411,698 		JBrowse link
G IFNGR1 interferon gamma receptor 1 involved_in ISO (PMID:20015550) UniProt PMID:20015550 NCBI chr 1:29,646,776...29,669,669
Ensembl chr 1:29,647,552...29,669,578 		JBrowse link
G IFNGR2 interferon gamma receptor 2 involved_in ISO (PMID:20015550) UniProt PMID:20015550 NCBI chr31:28,909,930...28,948,742 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17925
    cellular process 16926
      signal transduction 6329
        cell surface receptor signaling pathway 2806
          cytokine-mediated signaling pathway 493
            Kit signaling pathway + 4
            adiponectin-activated signaling pathway 8
            chemokine-mediated signaling pathway + 76
            ciliary neurotrophic factor-mediated signaling pathway 6
            erythropoietin-mediated signaling pathway 6
            granulocyte colony-stimulating factor signaling pathway 5
            granulocyte-macrophage colony-stimulating factor signaling pathway 4
            interferon-mediated signaling pathway + 81
            interleukin-1-mediated signaling pathway + 30
            interleukin-10-mediated signaling pathway 7
            interleukin-11-mediated signaling pathway 5
            interleukin-12-mediated signaling pathway 8
            interleukin-13-mediated signaling pathway 1
            interleukin-15-mediated signaling pathway 11
            interleukin-17-mediated signaling pathway + 13
            interleukin-17A-mediated signaling pathway 6
            interleukin-18-mediated signaling pathway + 10
            interleukin-19-mediated signaling pathway 0
            interleukin-2-mediated signaling pathway + 9
            interleukin-20-mediated signaling pathway 0
            interleukin-21-mediated signaling pathway 0
            interleukin-22-mediated signaling pathway 3
            interleukin-23-mediated signaling pathway 3
            interleukin-27-mediated signaling pathway + 8
            interleukin-3-mediated signaling pathway 7
            interleukin-32-mediated signaling pathway 0
            interleukin-33-mediated signaling pathway 8
            interleukin-34-mediated signaling pathway 1
            interleukin-35-mediated signaling pathway + 0
            interleukin-4-mediated signaling pathway + 9
            interleukin-5-mediated signaling pathway 6
            interleukin-6-mediated signaling pathway + 30
            interleukin-7-mediated signaling pathway 4
            interleukin-8-mediated signaling pathway 1
            interleukin-9-mediated signaling pathway 7
            leptin-mediated signaling pathway + 10
            macrophage colony-stimulating factor signaling pathway + 6
            macrophage migration inhibitory factor signaling pathway + 3
            negative regulation of cytokine-mediated signaling pathway + 96
            oncostatin-M-mediated signaling pathway 4
            positive regulation of cytokine-mediated signaling pathway + 57
            prolactin signaling pathway + 4
            regulation of cytokine-mediated signaling pathway + 166
            tumor necrosis factor-mediated signaling pathway + 102
Path 2
Term Annotations click to browse term
  biological_process 17925
    biological regulation 12448
      regulation of biological process 12084
        regulation of cellular process 11579
          signal transduction 6329
            cell surface receptor signaling pathway 2806
              cytokine-mediated signaling pathway 493
                Kit signaling pathway + 4
                adiponectin-activated signaling pathway 8
                chemokine-mediated signaling pathway + 76
                ciliary neurotrophic factor-mediated signaling pathway 6
                erythropoietin-mediated signaling pathway 6
                granulocyte colony-stimulating factor signaling pathway 5
                granulocyte-macrophage colony-stimulating factor signaling pathway 4
                interferon-mediated signaling pathway + 81
                interleukin-1-mediated signaling pathway + 30
                interleukin-10-mediated signaling pathway 7
                interleukin-11-mediated signaling pathway 5
                interleukin-12-mediated signaling pathway 8
                interleukin-13-mediated signaling pathway 1
                interleukin-15-mediated signaling pathway 11
                interleukin-17-mediated signaling pathway + 13
                interleukin-17A-mediated signaling pathway 6
                interleukin-18-mediated signaling pathway + 10
                interleukin-19-mediated signaling pathway 0
                interleukin-2-mediated signaling pathway + 9
                interleukin-20-mediated signaling pathway 0
                interleukin-21-mediated signaling pathway 0
                interleukin-22-mediated signaling pathway 3
                interleukin-23-mediated signaling pathway 3
                interleukin-27-mediated signaling pathway + 8
                interleukin-3-mediated signaling pathway 7
                interleukin-32-mediated signaling pathway 0
                interleukin-33-mediated signaling pathway 8
                interleukin-34-mediated signaling pathway 1
                interleukin-35-mediated signaling pathway + 0
                interleukin-4-mediated signaling pathway + 9
                interleukin-5-mediated signaling pathway 6
                interleukin-6-mediated signaling pathway + 30
                interleukin-7-mediated signaling pathway 4
                interleukin-8-mediated signaling pathway 1
                interleukin-9-mediated signaling pathway 7
                leptin-mediated signaling pathway + 10
                macrophage colony-stimulating factor signaling pathway + 6
                macrophage migration inhibitory factor signaling pathway + 3
                negative regulation of cytokine-mediated signaling pathway + 96
                oncostatin-M-mediated signaling pathway 4
                positive regulation of cytokine-mediated signaling pathway + 57
                prolactin signaling pathway + 4
                regulation of cytokine-mediated signaling pathway + 166
                tumor necrosis factor-mediated signaling pathway + 102
paths to the root