TRIM44 (tripartite motif containing 44) - Rat Genome Database

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Gene: TRIM44 (tripartite motif containing 44) Canis lupus familiaris
Analyze
Symbol: TRIM44
Name: tripartite motif containing 44
RGD ID: 12311818
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN response to angiotensin (ortholog); ASSOCIATED WITH aniridia (ortholog); Aniridia 3 (ortholog); Cardiomegaly (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tripartite motif-containing protein 44
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11832,242,830 - 32,351,540 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1832,247,146 - 32,351,648 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1831,849,489 - 31,958,122 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01832,853,137 - 32,961,804 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1832,853,874 - 32,962,301 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11832,414,167 - 32,522,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01831,999,405 - 32,108,058 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01832,644,829 - 32,753,492 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
TRIM44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11832,242,830 - 32,351,540 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1832,247,146 - 32,351,648 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1831,849,489 - 31,958,122 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01832,853,137 - 32,961,804 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1832,853,874 - 32,962,301 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11832,414,167 - 32,522,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01831,999,405 - 32,108,058 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01832,644,829 - 32,753,492 (-)NCBIUU_Cfam_GSD_1.0
TRIM44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381135,662,775 - 35,818,007 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1135,662,775 - 35,818,007 (+)EnsemblGRCh38hg38GRCh38
GRCh371135,684,323 - 35,839,557 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361135,640,929 - 35,786,351 (+)NCBINCBI36Build 36hg18NCBI36
Build 341135,640,928 - 35,786,333NCBI
Celera1135,831,618 - 35,978,179 (+)NCBICelera
Cytogenetic Map11p13NCBI
HuRef1135,382,982 - 35,529,605 (+)NCBIHuRef
CHM1_11135,682,770 - 35,829,354 (+)NCBICHM1_1
T2T-CHM13v2.01135,801,539 - 35,956,748 (+)NCBIT2T-CHM13v2.0
Trim44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392102,130,464 - 102,231,541 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2102,130,464 - 102,238,173 (-)EnsemblGRCm39 Ensembl
GRCm382102,300,119 - 102,400,900 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2102,300,119 - 102,407,828 (-)EnsemblGRCm38mm10GRCm38
MGSCv372102,140,276 - 102,241,057 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362102,100,958 - 102,201,739 (-)NCBIMGSCv36mm8
Celera2103,537,119 - 103,637,729 (-)NCBICelera
Cytogenetic Map2E2NCBI
cM Map254.13NCBI
Trim44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83109,048,643 - 109,183,821 (-)NCBIGRCr8
mRatBN7.2388,593,619 - 88,729,085 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl388,592,719 - 88,729,188 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx392,174,688 - 92,232,227 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03100,773,706 - 100,831,243 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0398,593,249 - 98,650,810 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0391,968,781 - 92,242,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl392,183,556 - 92,242,318 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0398,626,537 - 98,894,480 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4387,458,183 - 87,594,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1387,354,610 - 87,490,757 (-)NCBI
Celera387,703,331 - 87,822,337 (-)NCBICelera
Cytogenetic Map3q32NCBI
Trim44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542210,580,002 - 10,690,349 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542210,580,002 - 10,690,349 (-)NCBIChiLan1.0ChiLan1.0
TRIM44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2937,881,633 - 38,111,341 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11137,886,297 - 38,116,016 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,633,985 - 35,782,260 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11135,508,589 - 35,656,684 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1135,508,083 - 35,656,684 (+)Ensemblpanpan1.1panPan2
Trim44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494729,315,842 - 29,424,036 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365332,437,641 - 2,548,837 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365332,440,241 - 2,548,831 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl225,276,859 - 25,378,448 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1225,275,193 - 25,378,738 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2227,638,106 - 27,737,932 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,461,928 - 29,592,084 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,464,090 - 29,592,270 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038126,584,251 - 126,719,217 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476711,378,172 - 11,550,337 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476711,373,992 - 11,550,622 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRIM44
942 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 16 5 1 12 1 10 6
Low 5 5 6 6 1 6 5 6 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000011015   ⟹   ENSCAFP00000010210
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1832,288,409 - 32,351,648 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000061365   ⟹   ENSCAFP00000056475
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1832,247,146 - 32,351,648 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000081034   ⟹   ENSCAFP00000043908
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1832,247,358 - 32,351,648 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845036769   ⟹   ENSCAFP00845028789
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1832,853,874 - 32,962,301 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845036821   ⟹   ENSCAFP00845028828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1832,898,709 - 32,962,301 (-)Ensembl
RefSeq Acc Id: XM_022405323   ⟹   XP_022261031
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11832,288,394 - 32,351,540 (-)NCBI
Dog10K_Boxer_Tasha1831,893,646 - 31,958,122 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038424107   ⟹   XP_038280035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01832,853,137 - 32,961,804 (-)NCBI
RefSeq Acc Id: XM_038424108   ⟹   XP_038280036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01832,897,290 - 32,961,804 (-)NCBI
RefSeq Acc Id: XM_038500455   ⟹   XP_038356383
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11832,414,167 - 32,522,742 (-)NCBI
RefSeq Acc Id: XM_038563026   ⟹   XP_038418954
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01832,644,829 - 32,753,492 (-)NCBI
RefSeq Acc Id: XM_038563027   ⟹   XP_038418955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01832,688,975 - 32,753,492 (-)NCBI
RefSeq Acc Id: XM_038627149   ⟹   XP_038483077
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01831,999,405 - 32,108,058 (-)NCBI
RefSeq Acc Id: XM_038627150   ⟹   XP_038483078
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01832,044,412 - 32,108,058 (-)NCBI
RefSeq Acc Id: XM_540542   ⟹   XP_540542
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11832,242,830 - 32,351,540 (-)NCBI
Dog10K_Boxer_Tasha1831,849,489 - 31,958,122 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_540542   ⟸   XM_540542
- Peptide Label: isoform X1
- UniProtKB: A0A8P0NUA8 (UniProtKB/TrEMBL),   A0A8C0PPI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022261031   ⟸   XM_022405323
- Peptide Label: isoform X2
- UniProtKB: A0A8P0SCA0 (UniProtKB/TrEMBL),   A0A8C0PPI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000010210   ⟸   ENSCAFT00000011015
RefSeq Acc Id: ENSCAFP00000056475   ⟸   ENSCAFT00000061365
RefSeq Acc Id: ENSCAFP00000043908   ⟸   ENSCAFT00000081034
RefSeq Acc Id: XP_038356383   ⟸   XM_038500455
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038483077   ⟸   XM_038627149
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038483078   ⟸   XM_038627150
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038280035   ⟸   XM_038424107
- Peptide Label: isoform X1
- UniProtKB: A0A8I3S1Z8 (UniProtKB/TrEMBL),   A0A8C0PPI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038280036   ⟸   XM_038424108
- Peptide Label: isoform X2
- UniProtKB: A0A8I3PJ69 (UniProtKB/TrEMBL),   A0A8C0PPI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418954   ⟸   XM_038563026
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PPI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418955   ⟸   XM_038563027
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PPI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028828   ⟸   ENSCAFT00845036821
RefSeq Acc Id: ENSCAFP00845028789   ⟸   ENSCAFT00845036769
Protein Domains
B box-type

Promoters
RGD ID:13686475
Promoter ID:EPDNEW_C4543
Type:multiple initiation site
Name:TRIM44_1
Description:tripartite motif containing 44
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11832,351,537 - 32,351,597EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006848 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030024752 UniProtKB/TrEMBL
  ENSCAFG00845020854 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000011015.5 UniProtKB/TrEMBL
  ENSCAFT00000081034.2 UniProtKB/TrEMBL
  ENSCAFT00030045560.1 UniProtKB/TrEMBL
  ENSCAFT00845036769 ENTREZGENE
  ENSCAFT00845036769.1 UniProtKB/TrEMBL
  ENSCAFT00845036821 ENTREZGENE
  ENSCAFT00845036821.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.830.40 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_B-box UniProtKB/TrEMBL
NCBI Gene TRIM44 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE TRIM UniProtKB/TrEMBL
  TRIPARTITE MOTIF-CONTAINING PROTEIN 44 UniProtKB/TrEMBL
Pfam zf-B_box UniProtKB/TrEMBL
PROSITE ZF_BBOX UniProtKB/TrEMBL
SMART BBOX UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
UniProt A0A8C0PPI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PJ69 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S1Z8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NUA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SCA0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47823 ENTREZGENE