MIR101-2 (microRNA mir-101-2) - Rat Genome Database

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Gene: MIR101-2 (microRNA mir-101-2) Canis lupus familiaris
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Symbol: MIR101-2
Name: microRNA mir-101-2 (Ensembl:microRNA 101-2)
RGD ID: 12263817
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: cfa-mir-101-2; microRNA 101-2
RGD Orthologs
Human
Mouse
Rat
Pig
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,194,328 - 93,194,382 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,194,309 - 93,194,399 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0193,749,531 - 93,749,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,749,512 - 93,749,602 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,380,331 - 93,380,385 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,103,859 - 93,103,913 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,869,446 - 93,869,500 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
RISC complex  (IEA)
synapse  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:16381832   PMID:18392026  


Genomics

Comparative Map Data
MIR101-2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1193,194,328 - 93,194,382 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl193,194,309 - 93,194,399 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0193,749,531 - 93,749,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl193,749,512 - 93,749,602 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1193,380,331 - 93,380,385 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0193,103,859 - 93,103,913 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0193,869,446 - 93,869,500 (+)NCBIUU_Cfam_GSD_1.0
MIR101-2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3894,850,297 - 4,850,375 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl94,850,297 - 4,850,375 (+)EnsemblGRCh38hg38GRCh38
GRCh3794,850,297 - 4,850,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3694,840,296 - 4,840,374 (+)NCBINCBI36Build 36hg18NCBI36
Celera94,775,888 - 4,775,966 (+)NCBICelera
Cytogenetic Map9p24.1NCBI
HuRef94,805,891 - 4,805,969 (+)NCBIHuRef
CHM1_194,850,518 - 4,850,596 (+)NCBICHM1_1
T2T-CHM13v2.094,855,423 - 4,855,501 (+)NCBIT2T-CHM13v2.0
Mir101b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391929,112,679 - 29,112,775 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1929,112,679 - 29,112,775 (+)EnsemblGRCm39 Ensembl
GRCm381929,135,279 - 29,135,375 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1929,135,279 - 29,135,375 (+)EnsemblGRCm38mm10GRCm38
MGSCv371929,209,769 - 29,209,865 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1929,910,729 - 29,910,825 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1923.61NCBI
Mir101-2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81236,273,922 - 236,274,018 (+)NCBIGRCr8
mRatBN7.21226,860,371 - 226,860,467 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,860,371 - 226,860,467 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1235,262,206 - 235,262,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01242,191,870 - 242,191,966 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01235,010,639 - 235,010,735 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01247,263,723 - 247,263,819 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1247,263,723 - 247,263,819 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01254,503,393 - 254,503,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1224,011,283 - 224,011,379 (+)NCBICelera
Cytogenetic Map1q52NCBI
MIR101-1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1217,152,783 - 217,152,873 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11217,152,783 - 217,152,873 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21242,988,419 - 242,988,509 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

musculoskeletal system
High
Medium
Low
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000032637
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl193,194,309 - 93,194,399 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845028144
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl193,749,512 - 93,749,602 (+)Ensembl
RefSeq Acc Id: NR_049226
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1193,194,328 - 93,194,382 (+)NCBI
ROS_Cfam_1.0193,749,531 - 93,749,585 (+)NCBI
UMICH_Zoey_3.1193,380,331 - 93,380,385 (+)NCBI
UNSW_CanFamBas_1.0193,103,859 - 93,103,913 (+)NCBI
UU_Cfam_GSD_1.0193,869,446 - 93,869,500 (+)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000020530 Ensembl
  ENSCAFG00845015812 Ensembl, ENTREZGENE
Ensembl Transcript ENSCAFT00845028144 ENTREZGENE
miRBase MI0007995 ENTREZGENE
NCBI Gene MIR101-2 ENTREZGENE
RNAcentral URS00002CC426 RNACentral
  URS00007E38D3 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR101-2  microRNA mir-101-2    microRNA 101-2  Symbol and/or name change 5135510 APPROVED