STAT5B (signal transducer and activator of transcription 5B) - Rat Genome Database

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Gene: STAT5B (signal transducer and activator of transcription 5B) Canis lupus familiaris
Analyze
Symbol: STAT5B
Name: signal transducer and activator of transcription 5B
RGD ID: 12359015
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN activated T cell proliferation (ortholog); acute-phase response (ortholog); B cell differentiation (ortholog); PARTICIPATES IN erythropoietin signaling pathway; fibroblast growth factor signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; ASSOCIATED WITH Acute-Phase Reaction (ortholog); colon adenocarcinoma (ortholog); colorectal adenocarcinoma (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC490969
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,647,712 - 20,718,453 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,691,483 - 20,716,485 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,109,403 - 20,179,537 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,367,403 - 21,437,279 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,367,403 - 21,437,269 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,152,431 - 20,222,600 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,419,706 - 20,489,689 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,522,505 - 20,592,735 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activated T cell proliferation  (IEA,ISO)
acute-phase response  (ISO)
B cell differentiation  (IEA,ISO)
cell population proliferation  (IEA,ISO)
cell surface receptor signaling pathway via JAK-STAT  (IEA,ISO)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to growth factor stimulus  (IEA)
cellular response to hormone stimulus  (IEA)
cytokine-mediated signaling pathway  (IEA,ISO)
defense response  (IEA)
development of secondary female sexual characteristics  (IEA,ISO)
development of secondary male sexual characteristics  (IEA,ISO)
erythrocyte differentiation  (IEA,ISO)
female pregnancy  (IEA,ISO)
gamma-delta T cell differentiation  (IEA,ISO)
growth hormone receptor signaling pathway via JAK-STAT  (IEA)
lactation  (IEA,ISO)
lipid storage  (IEA,ISO)
liver development  (ISO)
luteinization  (IEA,ISO)
lymphocyte differentiation  (IEA,ISO)
mast cell migration  (IEA,ISO)
mitotic cell cycle  (IEA,ISO)
myeloid cell apoptotic process  (IEA,ISO)
natural killer cell differentiation  (IEA,ISO)
natural killer cell mediated cytotoxicity  (IEA,ISO)
natural killer cell proliferation  (IEA,ISO)
negative regulation of erythrocyte differentiation  (IEA,ISO)
negative regulation of myeloid cell apoptotic process  (IEA,ISO)
Peyer's patch development  (IEA,ISO)
positive regulation of activated T cell proliferation  (IEA,ISO)
positive regulation of B cell differentiation  (IEA,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of erythrocyte differentiation  (IEA)
positive regulation of fibroblast growth factor production  (ISO)
positive regulation of gamma-delta T cell differentiation  (IEA,ISO)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (IEA,ISO)
positive regulation of interleukin-2 production  (IEA,ISO)
positive regulation of lymphocyte differentiation  (IEA,ISO)
positive regulation of mitotic cell cycle  (IEA,ISO)
positive regulation of multicellular organism growth  (IEA,ISO)
positive regulation of natural killer cell differentiation  (IEA,ISO)
positive regulation of natural killer cell mediated cytotoxicity  (IEA,ISO)
positive regulation of natural killer cell proliferation  (IEA,ISO)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
progesterone metabolic process  (IEA,ISO)
regulation of cell adhesion  (IEA,ISO)
regulation of cell population proliferation  (IEA)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of epithelial cell differentiation  (IEA,ISO)
regulation of gene expression  (IEA)
regulation of multicellular organism growth  (IEA)
regulation of primary metabolic process  (IEA)
regulation of steroid metabolic process  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA,ISO)
response to estradiol  (IEA)
response to ethanol  (ISO)
response to hypoxia  (ISO)
response to interleukin-15  (IEA,ISO)
response to interleukin-2  (IEA,ISO)
response to interleukin-4  (IEA,ISO)
response to lipopolysaccharide  (ISO)
response to peptide hormone  (IEA,ISO)
sex differentiation  (IEA,ISO)
signal transduction  (IEA)
T cell differentiation in thymus  (IEA,ISO)
T cell homeostasis  (IEA,ISO)
taurine metabolic process  (IEA,ISO)
transcription by RNA polymerase II  (IEA,ISO)

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:10967132   PMID:30032202  


Genomics

Comparative Map Data
STAT5B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,647,712 - 20,718,453 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl920,691,483 - 20,716,485 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,109,403 - 20,179,537 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,367,403 - 21,437,279 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl921,367,403 - 21,437,269 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1920,152,431 - 20,222,600 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,419,706 - 20,489,689 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0920,522,505 - 20,592,735 (+)NCBIUU_Cfam_GSD_1.0
STAT5B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,199,177 - 42,288,370 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,199,176 - 42,288,633 (-)EnsemblGRCh38hg38GRCh38
GRCh371740,351,195 - 40,428,409 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,604,721 - 37,681,950 (-)NCBINCBI36Build 36hg18NCBI36
Build 341737,604,721 - 37,681,950NCBI
Celera1737,005,458 - 37,083,308 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1736,116,230 - 36,193,344 (-)NCBIHuRef
CHM1_11740,586,923 - 40,664,134 (-)NCBICHM1_1
T2T-CHM13v2.01743,055,661 - 43,144,521 (-)NCBIT2T-CHM13v2.0
Stat5b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,671,557 - 100,741,407 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,671,557 - 100,741,550 (-)EnsemblGRCm39 Ensembl
GRCm3811100,780,731 - 100,859,004 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,780,731 - 100,850,724 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711100,642,045 - 100,711,899 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,596,821 - 100,638,618 (-)NCBIMGSCv36mm8
MGSCv3611101,557,264 - 101,599,060 (-)NCBIMGSCv36mm8
Cytogenetic Map11DNCBI
cM Map1163.63NCBI
Stat5b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,205,148 - 86,276,178 (-)NCBIGRCr8
mRatBN7.21085,704,841 - 85,775,856 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,705,670 - 85,775,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,743,399 - 90,812,008 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,222,166 - 90,290,624 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,615,217 - 85,683,927 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,686,207 - 88,712,313 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,686,207 - 88,754,829 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01088,480,377 - 88,506,888 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,716,624 - 89,743,134 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,730,993 - 89,757,504 (-)NCBI
Celera1084,424,576 - 84,451,052 (-)NCBICelera
RH 3.4 Map10837.39RGD
Cytogenetic Map10q31NCBI
Stat5b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545116,253,645 - 16,295,337 (-)NCBIChiLan1.0ChiLan1.0
LOC100989105
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,696,139 - 22,784,759 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11724,586,321 - 24,674,917 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,040,303 - 15,116,682 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,306,412 - 15,338,973 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,306,418 - 15,336,463 (+)Ensemblpanpan1.1panPan2
LOC101954516
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560220,031,387 - 20,054,040 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649017,021,051 - 17,043,941 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649017,022,268 - 17,043,751 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STAT5B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1220,508,404 - 20,574,266 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11220,498,103 - 20,574,365 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21220,634,155 - 20,864,515 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103243413
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11663,997,486 - 64,070,392 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1663,997,441 - 64,070,445 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607734,795,632 - 34,884,310 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in STAT5B
526 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 10 6
Low 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005624461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005624462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014116559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_548092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB538856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ222754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000024702   ⟹   ENSCAFP00000022915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl920,691,483 - 20,716,485 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017531   ⟹   ENSCAFP00845013643
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl921,367,403 - 21,436,481 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845017626   ⟹   ENSCAFP00845013723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl921,367,427 - 21,437,269 (+)Ensembl
RefSeq Acc Id: XM_005624461   ⟹   XP_005624518
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,648,805 - 20,715,188 (+)NCBI
Dog10K_Boxer_Tasha920,109,872 - 20,176,272 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005624462   ⟹   XP_005624519
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,691,484 - 20,718,453 (+)NCBI
Dog10K_Boxer_Tasha920,152,842 - 20,179,537 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038485527   ⟹   XP_038341455
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1920,152,900 - 20,222,600 (+)NCBI
RefSeq Acc Id: XM_038485528   ⟹   XP_038341456
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1920,152,431 - 20,222,600 (+)NCBI
RefSeq Acc Id: XM_038485529   ⟹   XP_038341457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1920,152,899 - 20,219,334 (+)NCBI
RefSeq Acc Id: XM_038485530   ⟹   XP_038341458
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1920,195,919 - 20,222,600 (+)NCBI
RefSeq Acc Id: XM_038485531   ⟹   XP_038341459
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1920,199,281 - 20,222,600 (+)NCBI
RefSeq Acc Id: XM_038547293   ⟹   XP_038403221
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0920,522,975 - 20,592,735 (+)NCBI
RefSeq Acc Id: XM_038547294   ⟹   XP_038403222
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0920,522,505 - 20,592,735 (+)NCBI
RefSeq Acc Id: XM_038547295   ⟹   XP_038403223
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0920,522,974 - 20,589,469 (+)NCBI
RefSeq Acc Id: XM_038547296   ⟹   XP_038403224
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0920,565,994 - 20,592,735 (+)NCBI
RefSeq Acc Id: XM_038547297   ⟹   XP_038403225
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0920,569,367 - 20,592,735 (+)NCBI
RefSeq Acc Id: XM_038602762   ⟹   XP_038458690
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha920,109,403 - 20,179,537 (+)NCBI
RefSeq Acc Id: XM_038602790   ⟹   XP_038458718
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha920,156,207 - 20,179,537 (+)NCBI
RefSeq Acc Id: XM_038611261   ⟹   XP_038467189
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0920,419,706 - 20,489,689 (+)NCBI
RefSeq Acc Id: XM_038611262   ⟹   XP_038467190
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0920,420,172 - 20,489,689 (+)NCBI
RefSeq Acc Id: XM_038611263   ⟹   XP_038467191
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0920,419,706 - 20,486,423 (+)NCBI
RefSeq Acc Id: XM_038611264   ⟹   XP_038467192
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0920,462,763 - 20,489,689 (+)NCBI
RefSeq Acc Id: XM_038611265   ⟹   XP_038467193
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0920,466,130 - 20,489,689 (+)NCBI
RefSeq Acc Id: XM_038676451   ⟹   XP_038532379
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0921,367,403 - 21,437,279 (+)NCBI
RefSeq Acc Id: XM_038676452   ⟹   XP_038532380
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0921,367,869 - 21,437,279 (+)NCBI
RefSeq Acc Id: XM_038676453   ⟹   XP_038532381
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0921,367,403 - 21,434,013 (+)NCBI
RefSeq Acc Id: XM_038676454   ⟹   XP_038532382
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0921,410,458 - 21,437,279 (+)NCBI
RefSeq Acc Id: XM_038676455   ⟹   XP_038532383
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0921,413,826 - 21,437,279 (+)NCBI
RefSeq Acc Id: XM_548092   ⟹   XP_548092
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,648,806 - 20,718,453 (+)NCBI
Dog10K_Boxer_Tasha920,109,873 - 20,179,537 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005624518 (Get FASTA)   NCBI Sequence Viewer  
  XP_005624519 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341455 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341456 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341457 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341458 (Get FASTA)   NCBI Sequence Viewer  
  XP_038341459 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403221 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403222 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403223 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403224 (Get FASTA)   NCBI Sequence Viewer  
  XP_038403225 (Get FASTA)   NCBI Sequence Viewer  
  XP_038458690 (Get FASTA)   NCBI Sequence Viewer  
  XP_038458718 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467189 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467190 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467191 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467192 (Get FASTA)   NCBI Sequence Viewer  
  XP_038467193 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532379 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532380 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532381 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532382 (Get FASTA)   NCBI Sequence Viewer  
  XP_038532383 (Get FASTA)   NCBI Sequence Viewer  
  XP_548092 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAJ09630 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000022915.5
  ENSCAFP00030000458.1
  ENSCAFP00030000482.1
  ENSCAFP00040013745.1
  ENSCAFP00040013829.1
  ENSCAFP00845013643
  ENSCAFP00845013643.1
  ENSCAFP00845013723
  ENSCAFP00845013723.1
Reference Protein Sequences
RefSeq Acc Id: XP_005624518   ⟸   XM_005624461
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LWA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_548092   ⟸   XM_548092
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ2 (UniProtKB/TrEMBL),   A0A8C0S0Y3 (UniProtKB/TrEMBL),   A0A8I3RXG9 (UniProtKB/TrEMBL),   A0A8I3N974 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005624519   ⟸   XM_005624462
- Peptide Label: isoform X3
- UniProtKB: A0A8I3N974 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000022915   ⟸   ENSCAFT00000024702
RefSeq Acc Id: XP_038341456   ⟸   XM_038485528
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038341457   ⟸   XM_038485529
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038341455   ⟸   XM_038485527
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038341458   ⟸   XM_038485530
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038341459   ⟸   XM_038485531
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038467189   ⟸   XM_038611261
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038467191   ⟸   XM_038611263
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038467190   ⟸   XM_038611262
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038467192   ⟸   XM_038611264
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038467193   ⟸   XM_038611265
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038532379   ⟸   XM_038676451
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ2 (UniProtKB/TrEMBL),   A0A8C0S0Y3 (UniProtKB/TrEMBL),   A0A8I3RXG9 (UniProtKB/TrEMBL),   A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532381   ⟸   XM_038676453
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LWA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532380   ⟸   XM_038676452
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ2 (UniProtKB/TrEMBL),   A0A8C0S0Y3 (UniProtKB/TrEMBL),   A0A8I3RXG9 (UniProtKB/TrEMBL),   A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532382   ⟸   XM_038676454
- Peptide Label: isoform X3
- UniProtKB: A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532383   ⟸   XM_038676455
- Peptide Label: isoform X3
- UniProtKB: A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038458690   ⟸   XM_038602762
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ2 (UniProtKB/TrEMBL),   A0A8C0S0Y3 (UniProtKB/TrEMBL),   A0A8I3RXG9 (UniProtKB/TrEMBL),   A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038458718   ⟸   XM_038602790
- Peptide Label: isoform X3
- UniProtKB: A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403222   ⟸   XM_038547294
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ2 (UniProtKB/TrEMBL),   A0A8C0S0Y3 (UniProtKB/TrEMBL),   A0A8I3N974 (UniProtKB/TrEMBL),   A0A8I3RXG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403223   ⟸   XM_038547295
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LWA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403221   ⟸   XM_038547293
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KHJ2 (UniProtKB/TrEMBL),   A0A8C0S0Y3 (UniProtKB/TrEMBL),   A0A8I3N974 (UniProtKB/TrEMBL),   A0A8I3RXG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403224   ⟸   XM_038547296
- Peptide Label: isoform X3
- UniProtKB: A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403225   ⟸   XM_038547297
- Peptide Label: isoform X3
- UniProtKB: A0A8I3N974 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845013643   ⟸   ENSCAFT00845017531
RefSeq Acc Id: ENSCAFP00845013723   ⟸   ENSCAFT00845017626
Protein Domains
SH2   STAT transcription factor DNA-binding

Promoters
RGD ID:13684520
Promoter ID:EPDNEW_C2588
Type:single initiation site
Name:STAT5B_1
Description:signal transducer and activator of transcription 5B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,648,733 - 20,648,793EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000015509 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000321 UniProtKB/TrEMBL
  ENSCAFG00040008482 UniProtKB/TrEMBL
  ENSCAFG00845009970 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000024702.5 UniProtKB/TrEMBL
  ENSCAFT00030000521.1 UniProtKB/TrEMBL
  ENSCAFT00030000550.1 UniProtKB/TrEMBL
  ENSCAFT00040015851.1 UniProtKB/TrEMBL
  ENSCAFT00040015952.1 UniProtKB/TrEMBL
  ENSCAFT00845017531 ENTREZGENE
  ENSCAFT00845017531.1 UniProtKB/TrEMBL
  ENSCAFT00845017626 ENTREZGENE
  ENSCAFT00845017626.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.532.10 UniProtKB/TrEMBL
  2.60.40.630 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  STAT transcription factor, all-alpha domain UniProtKB/TrEMBL
InterPro p53-like_TF_DNA-bd UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  STAT UniProtKB/TrEMBL
  STAT5_CCD UniProtKB/TrEMBL
  STAT5a/5b UniProtKB/TrEMBL
  STAT5b_SH2 UniProtKB/TrEMBL
  STAT_linker UniProtKB/TrEMBL
  STAT_N_sf UniProtKB/TrEMBL
  STAT_TF_alpha UniProtKB/TrEMBL
  STAT_TF_coiled-coil UniProtKB/TrEMBL
  STAT_TF_DNA-bd UniProtKB/TrEMBL
  STAT_TF_DNA-bd_N UniProtKB/TrEMBL
  STAT_TF_prot_interaction UniProtKB/TrEMBL
NCBI Gene LOC490969 ENTREZGENE
PANTHER PTHR11801 UniProtKB/TrEMBL
  SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 5B UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  STAT_alpha UniProtKB/TrEMBL
  STAT_bind UniProtKB/TrEMBL
  STAT_int UniProtKB/TrEMBL
  STAT_linker UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  STAT_int UniProtKB/TrEMBL
Superfamily-SCOP SSF47655 UniProtKB/TrEMBL
  SSF48092 UniProtKB/TrEMBL
  SSF49417 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C0KHJ2 ENTREZGENE
  A0A8C0LWA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S0Y3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0S0Z0_CANLF UniProtKB/TrEMBL
  A0A8I3N974 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RXG9 ENTREZGENE, UniProtKB/TrEMBL
  D6RUR3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:55825 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-06-26 STAT5B  signal transducer and activator of transcription 5B  LOC490969    Symbol and/or name change 5135510 APPROVED