SLIT2 (slit guidance ligand 2) - Rat Genome Database

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Gene: SLIT2 (slit guidance ligand 2) Canis lupus familiaris
Analyze
Symbol: SLIT2
Name: slit guidance ligand 2
RGD ID: 12072172
Description: ENCODES a protein that exhibits chemorepellent activity (ortholog); heparan sulfate proteoglycan binding (ortholog); INVOLVED IN aortic valve morphogenesis (ortholog); axon guidance (ortholog); axonogenesis (ortholog); PARTICIPATES IN glypican signaling pathway; ASSOCIATED WITH acute promyelocytic leukemia (ortholog); anti-basement membrane glomerulonephritis (ortholog); atrial fibrillation (ortholog); FOUND IN axon (ortholog); cell body (ortholog); cell projection (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: slit homolog 2 protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1388,964,707 - 89,311,817 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl389,948,988 - 90,298,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1389,094,518 - 89,443,898 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve morphogenesis  (ISO)
apoptotic process involved in luteolysis  (IEA)
axon extension involved in axon guidance  (IEA)
axon guidance  (IEA,ISO)
axonogenesis  (ISO)
branching morphogenesis of an epithelial tube  (IEA)
cell differentiation  (IEA)
cell migration involved in sprouting angiogenesis  (IEA)
cell-cell adhesion  (ISO)
cellular response to heparin  (IEA)
cellular response to hormone stimulus  (IEA)
cellular response to hypoxia  (ISO)
cellular response to platelet-derived growth factor stimulus  (ISO)
chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration  (ISO)
chemorepulsion involved in postnatal olfactory bulb interneuron migration  (IEA)
corticospinal neuron axon guidance through spinal cord  (IEA)
dorsal/ventral axon guidance  (ISO)
in utero embryonic development  (ISO)
induction of negative chemotaxis  (IEA)
kidney development  (ISO)
mammary duct terminal end bud growth  (ISO)
mammary gland duct morphogenesis  (ISO)
metanephros development  (ISO)
motor neuron axon guidance  (IEA)
negative chemotaxis  (IBA,IEA,ISO)
negative regulation of actin filament polymerization  (IEA)
negative regulation of axon extension  (ISO)
negative regulation of cell growth  (IEA)
negative regulation of cell migration  (IEA)
negative regulation of cell population proliferation  (ISO)
negative regulation of cellular response to growth factor stimulus  (IEA)
negative regulation of chemokine-mediated signaling pathway  (IEA)
negative regulation of endothelial cell migration  (IEA)
negative regulation of gene expression  (ISO)
negative regulation of lamellipodium assembly  (IEA)
negative regulation of leukocyte chemotaxis  (IEA)
negative regulation of monocyte chemotaxis  (ISO)
negative regulation of mononuclear cell migration  (IEA)
negative regulation of neutrophil chemotaxis  (IEA)
negative regulation of protein phosphorylation  (ISO)
negative regulation of retinal ganglion cell axon guidance  (IEA)
negative regulation of small GTPase mediated signal transduction  (IEA)
negative regulation of smooth muscle cell chemotaxis  (IEA)
negative regulation of smooth muscle cell migration  (IEA)
negative regulation of vascular permeability  (IEA)
nervous system development  (IEA)
neuron projection extension  (ISO)
neuron projection morphogenesis  (ISO)
olfactory bulb development  (ISO)
positive regulation of apoptotic process  (IEA)
positive regulation of synapse assembly  (ISO)
pulmonary valve morphogenesis  (ISO)
response to cortisol  (IEA)
response to nutrient levels  (ISO)
retinal ganglion cell axon guidance  (IBA,IEA,ISO)
Roundabout signaling pathway  (IEA)
spinal cord development  (ISO)
synapse maturation  (ISO)
telencephalon cell migration  (ISO)
ureteric bud development  (IEA)
ventricular septum morphogenesis  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:17146174   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLIT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1388,964,707 - 89,311,817 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl389,948,988 - 90,298,073 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1389,094,518 - 89,443,898 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBIUU_Cfam_GSD_1.0
SLIT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38420,251,905 - 20,620,561 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl420,251,905 - 20,620,561 (+)EnsemblGRCh38hg38GRCh38
GRCh37420,253,528 - 20,622,184 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36419,864,333 - 20,229,886 (+)NCBINCBI36Build 36hg18NCBI36
Build 34419,931,503 - 20,297,057NCBI
Celera420,712,350 - 21,077,291 (+)NCBICelera
Cytogenetic Map4p15.31NCBI
HuRef419,604,199 - 19,969,514 (+)NCBIHuRef
CHM1_1420,253,276 - 20,618,733 (+)NCBICHM1_1
T2T-CHM13v2.0420,234,597 - 20,602,238 (+)NCBIT2T-CHM13v2.0
Slit2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39548,138,633 - 48,465,077 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl548,140,480 - 48,465,075 (+)EnsemblGRCm39 Ensembl
GRCm38547,981,291 - 48,307,735 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl547,983,138 - 48,307,733 (+)EnsemblGRCm38mm10GRCm38
MGSCv37548,374,394 - 48,697,017 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36548,273,041 - 48,593,759 (+)NCBIMGSCv36mm8
Celera545,381,658 - 45,708,133 (+)NCBICelera
Cytogenetic Map5B3NCBI
cM Map526.05NCBI
Slit2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81466,829,661 - 67,168,517 (-)NCBIGRCr8
mRatBN7.21462,616,337 - 62,955,934 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1462,617,067 - 62,955,948 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1467,016,997 - 67,353,404 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01468,330,637 - 68,667,055 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01464,727,393 - 65,063,822 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01466,831,848 - 67,171,491 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1466,831,848 - 67,170,361 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01466,864,065 - 67,202,691 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41467,546,283 - 67,891,840 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11467,624,799 - 67,894,206 (-)NCBI
Celera1461,665,582 - 62,001,006 (-)NCBICelera
Cytogenetic Map14q11NCBI
Slit2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554803,984,586 - 4,313,908 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554803,982,977 - 4,314,160 (-)NCBIChiLan1.0ChiLan1.0
SLIT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2320,490,764 - 20,869,771 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1420,698,666 - 21,066,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0414,654,448 - 15,023,708 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1419,946,369 - 20,314,656 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl420,158,952 - 20,314,656 (+)Ensemblpanpan1.1panPan2
Slit2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528554,409,516 - 54,746,912 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364778,109,228 - 8,446,653 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364778,111,212 - 8,448,567 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLIT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl814,758,335 - 15,148,133 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1814,758,426 - 15,149,515 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2814,998,769 - 15,257,500 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLIT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12729,650,589 - 30,020,105 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2729,650,337 - 29,803,612 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604776,267,556 - 76,654,726 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slit2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475511,472,377 - 11,819,266 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475511,470,810 - 11,819,800 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLIT2
6660 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014112671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014112672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014112673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014112674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014112675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022417276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022417277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038472605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038482448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038533596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038597879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038662102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB194048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000026343   ⟹   ENSCAFP00000024465
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl388,966,232 - 89,105,329 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000044488   ⟹   ENSCAFP00000038588
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000062102   ⟹   ENSCAFP00000044662
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000076619   ⟹   ENSCAFP00000065353
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000082842   ⟹   ENSCAFP00000059643
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000090541   ⟹   ENSCAFP00000053143
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl388,966,232 - 89,312,955 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845017852   ⟹   ENSCAFP00845013905
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl389,948,988 - 90,298,073 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845018027   ⟹   ENSCAFP00845014044
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl389,948,988 - 90,298,073 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845018350   ⟹   ENSCAFP00845014325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl389,948,988 - 90,298,073 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845018577   ⟹   ENSCAFP00845014491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl389,948,988 - 90,298,073 (-)Ensembl
RefSeq Acc Id: XM_014112671   ⟹   XP_013968146
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1388,964,707 - 89,311,816 (-)NCBI
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014112672   ⟹   XP_013968147
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1388,964,707 - 89,311,816 (-)NCBI
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014112673   ⟹   XP_013968148
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1388,964,707 - 89,311,816 (-)NCBI
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014112674   ⟹   XP_013968149
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1388,964,707 - 89,311,816 (-)NCBI
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014112675   ⟹   XP_013968150
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1388,964,707 - 89,311,817 (-)NCBI
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022417276   ⟹   XP_022272984
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1388,964,707 - 89,311,817 (-)NCBI
Dog10K_Boxer_Tasha391,423,926 - 91,773,328 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038472605   ⟹   XP_038328533
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1389,094,518 - 89,443,898 (-)NCBI
RefSeq Acc Id: XM_038482448   ⟹   XP_038338376
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha391,423,926 - 91,761,420 (-)NCBI
RefSeq Acc Id: XM_038533590   ⟹   XP_038389518
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBI
RefSeq Acc Id: XM_038533591   ⟹   XP_038389519
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBI
RefSeq Acc Id: XM_038533592   ⟹   XP_038389520
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBI
RefSeq Acc Id: XM_038533593   ⟹   XP_038389521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBI
RefSeq Acc Id: XM_038533594   ⟹   XP_038389522
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBI
RefSeq Acc Id: XM_038533595   ⟹   XP_038389523
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,912,569 (-)NCBI
RefSeq Acc Id: XM_038533596   ⟹   XP_038389524
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0389,562,948 - 89,900,592 (-)NCBI
RefSeq Acc Id: XM_038597873   ⟹   XP_038453801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBI
RefSeq Acc Id: XM_038597874   ⟹   XP_038453802
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBI
RefSeq Acc Id: XM_038597875   ⟹   XP_038453803
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBI
RefSeq Acc Id: XM_038597876   ⟹   XP_038453804
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBI
RefSeq Acc Id: XM_038597877   ⟹   XP_038453805
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBI
RefSeq Acc Id: XM_038597878   ⟹   XP_038453806
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,528,769 (-)NCBI
RefSeq Acc Id: XM_038597879   ⟹   XP_038453807
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0389,179,097 - 89,516,865 (-)NCBI
RefSeq Acc Id: XM_038662096   ⟹   XP_038518024
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBI
RefSeq Acc Id: XM_038662097   ⟹   XP_038518025
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBI
RefSeq Acc Id: XM_038662098   ⟹   XP_038518026
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBI
RefSeq Acc Id: XM_038662099   ⟹   XP_038518027
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBI
RefSeq Acc Id: XM_038662100   ⟹   XP_038518028
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBI
RefSeq Acc Id: XM_038662101   ⟹   XP_038518029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,297,465 (-)NCBI
RefSeq Acc Id: XM_038662102   ⟹   XP_038518030
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0389,948,981 - 90,285,517 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013968146 (Get FASTA)   NCBI Sequence Viewer  
  XP_013968147 (Get FASTA)   NCBI Sequence Viewer  
  XP_013968148 (Get FASTA)   NCBI Sequence Viewer  
  XP_013968149 (Get FASTA)   NCBI Sequence Viewer  
  XP_013968150 (Get FASTA)   NCBI Sequence Viewer  
  XP_022272984 (Get FASTA)   NCBI Sequence Viewer  
  XP_038328533 (Get FASTA)   NCBI Sequence Viewer  
  XP_038338376 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389518 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389519 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389520 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389521 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389522 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389523 (Get FASTA)   NCBI Sequence Viewer  
  XP_038389524 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453801 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453802 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453803 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453804 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453805 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453806 (Get FASTA)   NCBI Sequence Viewer  
  XP_038453807 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518024 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518025 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518026 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518027 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518028 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518029 (Get FASTA)   NCBI Sequence Viewer  
  XP_038518030 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD91587 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000024465.4
  ENSCAFP00000038588.3
  ENSCAFP00000044662.1
  ENSCAFP00000053143.1
  ENSCAFP00000059643.1
  ENSCAFP00000065353.1
  ENSCAFP00030001447.1
  ENSCAFP00030001512.1
  ENSCAFP00030001602.1
  ENSCAFP00030001711.1
  ENSCAFP00040004906.1
  ENSCAFP00040004919.1
  ENSCAFP00845013905.1
  ENSCAFP00845014044
  ENSCAFP00845014044.1
  ENSCAFP00845014325
  ENSCAFP00845014325.1
  ENSCAFP00845014491
  ENSCAFP00845014491.1
RefSeq Acc Id: XP_013968149   ⟸   XM_014112674
- Peptide Label: isoform X5
- UniProtKB: A0A8C0PWL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013968147   ⟸   XM_014112672
- Peptide Label: isoform X3
- UniProtKB: A0A8C0PVR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013968148   ⟸   XM_014112673
- Peptide Label: isoform X4
- UniProtKB: A0A8C0PWL5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013968150   ⟸   XM_014112675
- Peptide Label: isoform X6
- UniProtKB: A0A8C0LRZ8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013968146   ⟸   XM_014112671
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LX73 (UniProtKB/TrEMBL),   A0A8I3NDC9 (UniProtKB/TrEMBL),   A0A8C0PVR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022272984   ⟸   XM_022417276
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PVR3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000038588   ⟸   ENSCAFT00000044488
Ensembl Acc Id: ENSCAFP00000044662   ⟸   ENSCAFT00000062102
Ensembl Acc Id: ENSCAFP00000065353   ⟸   ENSCAFT00000076619
Ensembl Acc Id: ENSCAFP00000059643   ⟸   ENSCAFT00000082842
Ensembl Acc Id: ENSCAFP00000053143   ⟸   ENSCAFT00000090541
Ensembl Acc Id: ENSCAFP00000024465   ⟸   ENSCAFT00000026343
RefSeq Acc Id: XP_038328533   ⟸   XM_038472605
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038453805   ⟸   XM_038597877
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038453803   ⟸   XM_038597875
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038453804   ⟸   XM_038597876
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038453806   ⟸   XM_038597878
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038453802   ⟸   XM_038597874
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038453801   ⟸   XM_038597873
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038453807   ⟸   XM_038597879
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038518028   ⟸   XM_038662100
- Peptide Label: isoform X5
- UniProtKB: A0A8C0PWL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038518026   ⟸   XM_038662098
- Peptide Label: isoform X3
- UniProtKB: A0A8C0PVR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038518027   ⟸   XM_038662099
- Peptide Label: isoform X4
- UniProtKB: A0A8C0PWL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038518029   ⟸   XM_038662101
- Peptide Label: isoform X6
- UniProtKB: A0A8C0LRZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038518025   ⟸   XM_038662097
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PVR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038518024   ⟸   XM_038662096
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LX73 (UniProtKB/TrEMBL),   A0A8I3NDC9 (UniProtKB/TrEMBL),   A0A8C0PVR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038518030   ⟸   XM_038662102
- Peptide Label: isoform X7
- UniProtKB: A0A8P0SKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038338376   ⟸   XM_038482448
- Peptide Label: isoform X7
- UniProtKB: A0A8P0SKY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389522   ⟸   XM_038533594
- Peptide Label: isoform X5
- UniProtKB: A0A8C0PWL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389520   ⟸   XM_038533592
- Peptide Label: isoform X3
- UniProtKB: A0A8C0PVR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389521   ⟸   XM_038533593
- Peptide Label: isoform X4
- UniProtKB: A0A8C0PWL5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389523   ⟸   XM_038533595
- Peptide Label: isoform X6
- UniProtKB: A0A8C0LRZ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389519   ⟸   XM_038533591
- Peptide Label: isoform X2
- UniProtKB: A0A8C0PVR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389518   ⟸   XM_038533590
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LX73 (UniProtKB/TrEMBL),   A0A8C0PVR3 (UniProtKB/TrEMBL),   A0A8I3NDC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038389524   ⟸   XM_038533596
- Peptide Label: isoform X7
- UniProtKB: A0A8P0SKY9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845014491   ⟸   ENSCAFT00845018577
Ensembl Acc Id: ENSCAFP00845014044   ⟸   ENSCAFT00845018027
Ensembl Acc Id: ENSCAFP00845013905   ⟸   ENSCAFT00845017852
Ensembl Acc Id: ENSCAFP00845014325   ⟸   ENSCAFT00845018350
Protein Domains
CTCK   EGF-like   Laminin G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016608 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000940 UniProtKB/TrEMBL
  ENSCAFG00040002597 UniProtKB/TrEMBL
  ENSCAFG00845010097 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026343.5 UniProtKB/TrEMBL
  ENSCAFT00000044488.4 UniProtKB/TrEMBL
  ENSCAFT00000062102.2 UniProtKB/TrEMBL
  ENSCAFT00000076619.2 UniProtKB/TrEMBL
  ENSCAFT00000082842.2 UniProtKB/TrEMBL
  ENSCAFT00000090541.2 UniProtKB/TrEMBL
  ENSCAFT00030001624.1 UniProtKB/TrEMBL
  ENSCAFT00030001696.1 UniProtKB/TrEMBL
  ENSCAFT00030001804.1 UniProtKB/TrEMBL
  ENSCAFT00030001929.1 UniProtKB/TrEMBL
  ENSCAFT00040005700.1 UniProtKB/TrEMBL
  ENSCAFT00040005715.1 UniProtKB/TrEMBL
  ENSCAFT00845017852.1 UniProtKB/TrEMBL
  ENSCAFT00845018027 ENTREZGENE
  ENSCAFT00845018027.1 UniProtKB/TrEMBL
  ENSCAFT00845018350 ENTREZGENE
  ENSCAFT00845018350.1 UniProtKB/TrEMBL
  ENSCAFT00845018577 ENTREZGENE
  ENSCAFT00845018577.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
  Laminin UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Cys_knot_C UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Fol_N UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  Notch/Slit_guidance UniProtKB/TrEMBL
KEGG Report cfa:595148 UniProtKB/TrEMBL
NCBI Gene SLIT2 ENTREZGENE
PANTHER SLIT HOMOLOG UniProtKB/TrEMBL
  SLIT HOMOLOG 2 PROTEIN UniProtKB/TrEMBL
Pfam EGF UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/TrEMBL
  Laminin_G_2 UniProtKB/TrEMBL
  LRR_1 UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
PRINTS EGFBLOOD UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  CTCK_1 UniProtKB/TrEMBL
  CTCK_2 UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  FOLN UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  LRRNT UniProtKB/TrEMBL
  SM00041 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  L domain-like UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A8C0LRZ8 ENTREZGENE
  A0A8C0LTK6_CANLF UniProtKB/TrEMBL
  A0A8C0LTU3_CANLF UniProtKB/TrEMBL
  A0A8C0LWJ6_CANLF UniProtKB/TrEMBL
  A0A8C0LX73 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PVR3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PWL5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NDC9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NF96_CANLF UniProtKB/TrEMBL
  A0A8I3NQC4_CANLF UniProtKB/TrEMBL
  A0A8I3RVP2_CANLF UniProtKB/TrEMBL
  A0A8P0NQ66_CANLF UniProtKB/TrEMBL
  A0A8P0SKY9 ENTREZGENE, UniProtKB/TrEMBL
  Q59I57_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0P2T3 UniProtKB/TrEMBL
VGNC ID VGNC:46504 ENTREZGENE