RELA (RELA proto-oncogene, NF-kB subunit) - Rat Genome Database

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Gene: RELA (RELA proto-oncogene, NF-kB subunit) Canis lupus familiaris
Analyze
Symbol: RELA
Name: RELA proto-oncogene, NF-kB subunit
RGD ID: 12347408
Description: ENCODES a protein that exhibits double-stranded DNA binding (ortholog); protein-containing complex binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN acetaldehyde metabolic process (ortholog); aging (ortholog); animal organ morphogenesis (ortholog); PARTICIPATES IN ceramide signaling pathway; interleukin-1 signaling pathway; interleukin-12 signaling pathway; ASSOCIATED WITH acute necrotizing pancreatitis (ortholog); alcoholic liver cirrhosis (ortholog); amphetamine abuse (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH arsenite(3-); lipopolysaccharide; NS-398
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transcription factor p65; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,550,003 - 51,558,861 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,550,040 - 51,558,875 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,158,512 - 50,167,377 (+)NCBI
ROS_Cfam_1.01852,587,297 - 52,596,161 (+)NCBI
ROS_Cfam_1.0 Ensembl1852,587,329 - 52,596,159 (+)Ensembl
UMICH_Zoey_3.11851,687,144 - 51,696,009 (+)NCBI
UNSW_CanFamBas_1.01851,261,264 - 51,270,127 (+)NCBI
UU_Cfam_GSD_1.01852,051,615 - 52,060,481 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute necrotizing pancreatitis  (ISO)
alcoholic liver cirrhosis  (ISO)
amphetamine abuse  (ISO)
anaplastic large cell lymphoma  (ISO)
arteriosclerosis  (ISO)
Bardet-Biedl syndrome  (ISO)
Barrett's esophagus  (ISO)
Brain Injuries  (ISO)
Brain Injuries, Traumatic  (ISO)
brain ischemia  (ISO)
Brain Neoplasms  (ISO)
Breast Neoplasms  (ISO)
Cardiomegaly  (ISO)
Cerebral Hemorrhage  (ISO)
cervix uteri carcinoma in situ  (ISO)
Childhood Schizophrenia  (ISO)
cholestasis  (ISO)
cholesteatoma of middle ear  (ISO)
colitis  (ISO)
Colonic Neoplasms  (ISO)
cryptorchidism  (ISO)
cystitis  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
Disease Progression  (ISO)
Drug Eruptions  (ISO)
Drug-Induced Dyskinesia  (ISO)
ductal carcinoma in situ  (ISO)
encephalitis  (ISO)
end stage renal disease  (ISO)
epilepsy  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Neoplasms  (ISO)
extrahepatic cholestasis  (ISO)
familial temporal lobe epilepsy 8  (ISO)
fatty liver disease  (ISO)
glycogen storage disease V  (ISO)
Heat Stroke  (ISO)
Hemorrhagic Shock  (ISO)
Hepatic Insufficiency  (ISO)
Hepatomegaly  (ISO)
high grade glioma  (ISO)
hypertension  (ISO)
Insulin Resistance  (ISO)
intellectual disability  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (ISO)
lung non-small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
lymphoma  (ISO)
Mammary Neoplasms, Experimental  (ISO)
mastoiditis  (ISO)
MUCOCUTANEOUS ULCERATION, CHRONIC  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplastic Cell Transformation  (ISO)
neuroblastoma  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
otitis media  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
pancreatic carcinoma  (ISO)
Parkinsonism  (ISO)
Pneumococcal Meningitis  (ISO)
primary biliary cholangitis  (ISO)
prostate adenocarcinoma  (ISO)
prostate carcinoma in situ  (ISO)
prostatic hypertrophy  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary hypertension  (ISO)
renal cell carcinoma  (ISO)
renovascular hypertension  (ISO)
Reperfusion Injury  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Subarachnoid Hemorrhage  (ISO)
Transplant Rejection  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
uveitis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acetaldehyde metabolic process  (ISO)
aging  (ISO)
animal organ morphogenesis  (IEA,ISO)
cellular response to angiotensin  (IEA)
cellular response to hepatocyte growth factor stimulus  (IEA,ISO)
cellular response to hydrogen peroxide  (IEA)
cellular response to interleukin-1  (IEA)
cellular response to interleukin-6  (IEA)
cellular response to lipopolysaccharide  (IEA,ISO)
cellular response to lipoteichoic acid  (IEA)
cellular response to nicotine  (IEA)
cellular response to peptidoglycan  (IEA)
cellular response to tumor necrosis factor  (IEA,ISO)
cellular response to vascular endothelial growth factor stimulus  (IEA)
chromatin organization  (IEA)
cytokine-mediated signaling pathway  (IEA)
defense response  (IEA,ISO)
defense response to tumor cell  (IEA)
DNA-templated transcription  (IEA)
hair follicle development  (IEA,ISO)
I-kappaB kinase/NF-kappaB signaling  (IBA)
inflammatory response  (IBA,IEA)
innate immune response  (IBA)
interleukin-1-mediated signaling pathway  (IEA)
liver development  (IEA)
negative regulation of apoptotic process  (IEA)
negative regulation of DNA-templated transcription  (IEA)
negative regulation of extrinsic apoptotic signaling pathway  (IEA,ISO)
negative regulation of insulin receptor signaling pathway  (ISO)
negative regulation of miRNA transcription  (IEA)
negative regulation of NIK/NF-kappaB signaling  (IEA)
negative regulation of protein catabolic process  (IEA,ISO)
negative regulation of protein sumoylation  (IEA)
negative regulation of transcription by RNA polymerase II  (IEA)
neuropeptide signaling pathway  (IEA)
NIK/NF-kappaB signaling  (IBA)
nucleotide-binding oligomerization domain containing 2 signaling pathway  (IEA,ISO)
positive regulation of amyloid-beta formation  (IEA,ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of chondrocyte differentiation  (ISO)
positive regulation of DNA-templated transcription  (IEA,ISO)
positive regulation of gene expression  (IEA)
positive regulation of I-kappaB kinase/NF-kappaB signaling  (IEA)
positive regulation of interleukin-12 production  (IEA,ISO)
positive regulation of interleukin-8 production  (IEA)
positive regulation of leukocyte adhesion to vascular endothelial cell  (IEA)
positive regulation of miRNA metabolic process  (IEA)
positive regulation of miRNA transcription  (IEA)
positive regulation of NF-kappaB transcription factor activity  (IEA,ISO)
positive regulation of NIK/NF-kappaB signaling  (IEA)
positive regulation of Schwann cell differentiation  (ISO)
positive regulation of T cell receptor signaling pathway  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA)
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus  (IEA)
postsynapse to nucleus signaling pathway  (IEA)
protein catabolic process  (IEA,ISO)
regulation of DNA-templated transcription  (IEA)
regulation of DNA-templated transcription in response to stress  (IEA)
regulation of inflammatory response  (IEA,ISO)
regulation of NIK/NF-kappaB signaling  (IEA)
regulation of transcription by RNA polymerase II  (IBA)
response to amino acid  (ISO)
response to bacterium  (IEA,ISO)
response to cAMP  (ISO)
response to cobalamin  (ISO)
response to cytokine  (IBA,ISO)
response to hydrogen peroxide  (ISO)
response to inorganic substance  (ISO)
response to insulin  (ISO)
response to interleukin-1  (IEA)
response to lipopolysaccharide  (ISO)
response to mechanical stimulus  (ISO)
response to morphine  (ISO)
response to muramyl dipeptide  (IEA,ISO)
response to muscle stretch  (IEA,ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (IEA,ISO)
response to progesterone  (ISO)
response to UV-B  (IEA)
response to xenobiotic stimulus  (ISO)
tumor necrosis factor-mediated signaling pathway  (IEA)

Cellular Component

References
Additional References at PubMed
PMID:30562372  


Genomics

Comparative Map Data
RELA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,550,003 - 51,558,861 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,550,040 - 51,558,875 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1850,158,512 - 50,167,377 (+)NCBI
ROS_Cfam_1.01852,587,297 - 52,596,161 (+)NCBI
ROS_Cfam_1.0 Ensembl1852,587,329 - 52,596,159 (+)Ensembl
UMICH_Zoey_3.11851,687,144 - 51,696,009 (+)NCBI
UNSW_CanFamBas_1.01851,261,264 - 51,270,127 (+)NCBI
UU_Cfam_GSD_1.01852,051,615 - 52,060,481 (+)NCBI
RELA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,653,601 - 65,662,916 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1165,653,599 - 65,663,090 (-)EnsemblGRCh38hg38GRCh38
GRCh371165,421,072 - 65,430,387 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,178,393 - 65,186,951 (-)NCBINCBI36hg18NCBI36
Build 341165,178,392 - 65,186,951NCBI
Celera1162,747,772 - 62,757,128 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,748,056 - 61,757,436 (-)NCBIHuRef
CHM1_11165,305,002 - 65,314,374 (-)NCBICHM1_1
T2T-CHM13v2.01165,647,771 - 65,657,086 (-)NCBI
Rela
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,687,569 - 5,698,162 (+)NCBIGRCm39mm39
GRCm39 Ensembl195,687,511 - 5,698,158 (+)Ensembl
GRCm38195,637,442 - 5,648,134 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,637,483 - 5,648,130 (+)EnsemblGRCm38mm10GRCm38
MGSCv37195,637,490 - 5,648,130 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,637,490 - 5,648,130 (+)NCBImm8
Celera195,507,082 - 5,517,707 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
Rela
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21202,925,001 - 202,935,484 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1202,924,945 - 202,935,484 (+)Ensembl
Rnor_6.01220,992,770 - 221,003,249 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,992,770 - 221,003,249 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,928,092 - 227,938,571 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41208,262,669 - 208,273,148 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11208,416,121 - 208,426,601 (+)NCBI
Celera1200,460,753 - 200,471,232 (+)NCBICelera
Cytogenetic Map1q43NCBI
Rela
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,603,345 - 19,611,516 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542219,602,930 - 19,612,263 (+)NCBIChiLan1.0ChiLan1.0
RELA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11164,347,859 - 64,357,461 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,347,859 - 64,356,868 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01161,012,839 - 61,022,225 (-)NCBIMhudiblu_PPA_v0panPan3
Rela
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,359,432 - 7,368,234 (+)NCBI
SpeTri2.0NW_0049365993,800,142 - 3,810,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RELA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,593,969 - 6,603,469 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.126,594,869 - 6,602,684 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,699,452 - 5,707,267 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RELA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,576,059 - 8,585,561 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl18,576,542 - 8,586,516 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038105,871,180 - 105,881,402 (+)NCBIVero_WHO_p1.0
Rela
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,732,938 - 20,741,272 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462476720,732,813 - 20,742,016 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 6 12 8 10 6
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005631472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005631473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005631474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014121307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022405652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038424980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038501238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038563920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038628047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_540850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ353849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000021166   ⟹   ENSCAFP00000019655
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1851,550,040 - 51,558,875 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000077303   ⟹   ENSCAFP00000064376
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1851,550,040 - 51,556,935 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000090501   ⟹   ENSCAFP00000065170
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1851,550,040 - 51,558,075 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845033625   ⟹   ENSCAFP00845026326
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1852,587,329 - 52,596,159 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845033705   ⟹   ENSCAFP00845026386
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1852,587,329 - 52,595,375 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845033784   ⟹   ENSCAFP00845026441
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1852,587,329 - 52,594,235 (+)Ensembl
RefSeq Acc Id: XM_005631472   ⟹   XP_005631529
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,413 - 51,558,861 (+)NCBI
Dog10K_Boxer_Tasha1850,158,933 - 50,167,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005631473   ⟹   XP_005631530
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,003 - 51,558,860 (+)NCBI
Dog10K_Boxer_Tasha1850,158,535 - 50,167,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005631474   ⟹   XP_005631531
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,262 - 51,558,861 (+)NCBI
Dog10K_Boxer_Tasha1850,158,777 - 50,167,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014121307   ⟹   XP_013976782
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,435 - 51,558,861 (+)NCBI
Dog10K_Boxer_Tasha1850,158,949 - 50,167,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022405652   ⟹   XP_022261360
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,278 - 51,558,861 (+)NCBI
Dog10K_Boxer_Tasha1850,158,819 - 50,167,377 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038424975   ⟹   XP_038280903
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01852,587,734 - 52,596,161 (+)NCBI
RefSeq Acc Id: XM_038424976   ⟹   XP_038280904
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01852,587,718 - 52,596,161 (+)NCBI
RefSeq Acc Id: XM_038424977   ⟹   XP_038280905
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01852,587,320 - 52,596,161 (+)NCBI
RefSeq Acc Id: XM_038424978   ⟹   XP_038280906
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01852,587,297 - 52,596,161 (+)NCBI
RefSeq Acc Id: XM_038424979   ⟹   XP_038280907
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01852,587,562 - 52,596,161 (+)NCBI
RefSeq Acc Id: XM_038424980   ⟹   XP_038280908
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01852,587,604 - 52,596,161 (+)NCBI
RefSeq Acc Id: XM_038501233   ⟹   XP_038357161
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11851,687,581 - 51,696,009 (+)NCBI
RefSeq Acc Id: XM_038501234   ⟹   XP_038357162
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11851,687,565 - 51,696,009 (+)NCBI
RefSeq Acc Id: XM_038501235   ⟹   XP_038357163
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11851,687,167 - 51,696,009 (+)NCBI
RefSeq Acc Id: XM_038501236   ⟹   XP_038357164
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11851,687,144 - 51,696,009 (+)NCBI
RefSeq Acc Id: XM_038501237   ⟹   XP_038357165
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11851,687,409 - 51,696,009 (+)NCBI
RefSeq Acc Id: XM_038501238   ⟹   XP_038357166
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11851,687,451 - 51,696,009 (+)NCBI
RefSeq Acc Id: XM_038563915   ⟹   XP_038419843
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01852,052,052 - 52,060,481 (+)NCBI
RefSeq Acc Id: XM_038563916   ⟹   XP_038419844
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01852,052,036 - 52,060,481 (+)NCBI
RefSeq Acc Id: XM_038563917   ⟹   XP_038419845
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01852,051,638 - 52,060,481 (+)NCBI
RefSeq Acc Id: XM_038563918   ⟹   XP_038419846
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01852,051,615 - 52,060,481 (+)NCBI
RefSeq Acc Id: XM_038563919   ⟹   XP_038419847
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01852,051,880 - 52,060,481 (+)NCBI
RefSeq Acc Id: XM_038563920   ⟹   XP_038419848
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01852,051,922 - 52,060,481 (+)NCBI
RefSeq Acc Id: XM_038628042   ⟹   XP_038483970
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01851,261,701 - 51,270,127 (+)NCBI
RefSeq Acc Id: XM_038628043   ⟹   XP_038483971
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01851,261,685 - 51,270,127 (+)NCBI
RefSeq Acc Id: XM_038628044   ⟹   XP_038483972
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01851,261,287 - 51,270,127 (+)NCBI
RefSeq Acc Id: XM_038628045   ⟹   XP_038483973
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01851,261,264 - 51,270,127 (+)NCBI
RefSeq Acc Id: XM_038628046   ⟹   XP_038483974
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01851,261,529 - 51,270,127 (+)NCBI
RefSeq Acc Id: XM_038628047   ⟹   XP_038483975
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01851,261,571 - 51,270,127 (+)NCBI
RefSeq Acc Id: XM_540850   ⟹   XP_540850
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,007 - 51,558,860 (+)NCBI
Dog10K_Boxer_Tasha1850,158,512 - 50,167,377 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005631529 (Get FASTA)   NCBI Sequence Viewer  
  XP_005631530 (Get FASTA)   NCBI Sequence Viewer  
  XP_005631531 (Get FASTA)   NCBI Sequence Viewer  
  XP_013976782 (Get FASTA)   NCBI Sequence Viewer  
  XP_022261360 (Get FASTA)   NCBI Sequence Viewer  
  XP_038280903 (Get FASTA)   NCBI Sequence Viewer  
  XP_038280904 (Get FASTA)   NCBI Sequence Viewer  
  XP_038280905 (Get FASTA)   NCBI Sequence Viewer  
  XP_038280906 (Get FASTA)   NCBI Sequence Viewer  
  XP_038280907 (Get FASTA)   NCBI Sequence Viewer  
  XP_038280908 (Get FASTA)   NCBI Sequence Viewer  
  XP_038357161 (Get FASTA)   NCBI Sequence Viewer  
  XP_038357162 (Get FASTA)   NCBI Sequence Viewer  
  XP_038357163 (Get FASTA)   NCBI Sequence Viewer  
  XP_038357164 (Get FASTA)   NCBI Sequence Viewer  
  XP_038357165 (Get FASTA)   NCBI Sequence Viewer  
  XP_038357166 (Get FASTA)   NCBI Sequence Viewer  
  XP_038419843 (Get FASTA)   NCBI Sequence Viewer  
  XP_038419844 (Get FASTA)   NCBI Sequence Viewer  
  XP_038419845 (Get FASTA)   NCBI Sequence Viewer  
  XP_038419846 (Get FASTA)   NCBI Sequence Viewer  
  XP_038419847 (Get FASTA)   NCBI Sequence Viewer  
  XP_038419848 (Get FASTA)   NCBI Sequence Viewer  
  XP_038483970 (Get FASTA)   NCBI Sequence Viewer  
  XP_038483971 (Get FASTA)   NCBI Sequence Viewer  
  XP_038483972 (Get FASTA)   NCBI Sequence Viewer  
  XP_038483973 (Get FASTA)   NCBI Sequence Viewer  
  XP_038483974 (Get FASTA)   NCBI Sequence Viewer  
  XP_038483975 (Get FASTA)   NCBI Sequence Viewer  
  XP_540850 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABC86233 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005631530   ⟸   XM_005631473
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_540850   ⟸   XM_540850
- Peptide Label: isoform X4
- UniProtKB: F1PCU1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005631531   ⟸   XM_005631474
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_013976782   ⟸   XM_014121307
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005631529   ⟸   XM_005631472
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022261360   ⟸   XM_022405652
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCAFP00000019655   ⟸   ENSCAFT00000021166
RefSeq Acc Id: ENSCAFP00000064376   ⟸   ENSCAFT00000077303
RefSeq Acc Id: ENSCAFP00000065170   ⟸   ENSCAFT00000090501
RefSeq Acc Id: XP_038357164   ⟸   XM_038501236
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038357163   ⟸   XM_038501235
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038357165   ⟸   XM_038501237
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038357166   ⟸   XM_038501238
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038357162   ⟸   XM_038501234
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038357161   ⟸   XM_038501233
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038483973   ⟸   XM_038628045
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038483972   ⟸   XM_038628044
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038483974   ⟸   XM_038628046
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038483975   ⟸   XM_038628047
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038483971   ⟸   XM_038628043
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038483970   ⟸   XM_038628042
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038280906   ⟸   XM_038424978
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038280905   ⟸   XM_038424977
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038280907   ⟸   XM_038424979
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038280908   ⟸   XM_038424980
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038280904   ⟸   XM_038424976
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038280903   ⟸   XM_038424975
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038419846   ⟸   XM_038563918
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038419845   ⟸   XM_038563917
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038419847   ⟸   XM_038563919
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038419848   ⟸   XM_038563920
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038419844   ⟸   XM_038563916
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038419843   ⟸   XM_038563915
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845026441   ⟸   ENSCAFT00845033784
RefSeq Acc Id: ENSCAFP00845026386   ⟸   ENSCAFT00845033705
RefSeq Acc Id: ENSCAFP00845026326   ⟸   ENSCAFT00845033625
Protein Domains
RHD

Promoters
RGD ID:13686601
Promoter ID:EPDNEW_C4669
Type:initiation region
Name:RELA_1
Description:RELA proto-oncogene, NF-kB subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11851,550,045 - 51,550,105EPDNEW
Damaging Variants


Assembly: CanFam3.1

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
18 51552685 51552686 G A snv Wolf (WO002_732)
18 51556669 51556670 C T snv Bearded Collie (BD089), Miniature Bullterrier (BT007), Landseer (ZS14), Pembroke Welsh Corgi (SRS732551), Shetland Sheepdog (SRS932138), Shetland Sheepdog (SS004), Bearded Collie (BD036), Bullterrier (BT012)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013334 Ensembl
  ENSCAFG00030013567 UniProtKB/TrEMBL
  ENSCAFG00040016546 UniProtKB/TrEMBL
  ENSCAFG00845019016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030021970.1 UniProtKB/TrEMBL
  ENSCAFP00030021986.1 UniProtKB/TrEMBL
  ENSCAFP00030022013.1 UniProtKB/TrEMBL
  ENSCAFP00040026571 UniProtKB/TrEMBL
  ENSCAFP00040026642 UniProtKB/TrEMBL
  ENSCAFP00040026672 UniProtKB/TrEMBL
  ENSCAFP00845026326 ENTREZGENE
  ENSCAFP00845026326.1 UniProtKB/TrEMBL
  ENSCAFP00845026386.1 UniProtKB/TrEMBL
  ENSCAFP00845026441.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030025165.1 UniProtKB/TrEMBL
  ENSCAFT00030025183.1 UniProtKB/TrEMBL
  ENSCAFT00030025211.1 UniProtKB/TrEMBL
  ENSCAFT00040030571 UniProtKB/TrEMBL
  ENSCAFT00040030648 UniProtKB/TrEMBL
  ENSCAFT00040030682 UniProtKB/TrEMBL
  ENSCAFT00845033625 ENTREZGENE
  ENSCAFT00845033625.1 UniProtKB/TrEMBL
  ENSCAFT00845033705.1 UniProtKB/TrEMBL
  ENSCAFT00845033784.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  2.60.40.340 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  IPT_NFkappaB UniProtKB/TrEMBL
  NFkB/Dor UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/TrEMBL
  RelA UniProtKB/TrEMBL
  RHD_CS UniProtKB/TrEMBL
  RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind_dom UniProtKB/TrEMBL
  RHD_DNA_bind_dom_sf UniProtKB/TrEMBL
NCBI Gene RELA ENTREZGENE
PANTHER PTHR24169 UniProtKB/TrEMBL
  PTHR24169:SF1 UniProtKB/TrEMBL
Pfam RHD_dimer UniProtKB/TrEMBL
  RHD_DNA_bind UniProtKB/TrEMBL
PRINTS NFKBTNSCPFCT UniProtKB/TrEMBL
PROSITE REL_1 UniProtKB/TrEMBL
  REL_2 UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A8C0N5N6_CANLF UniProtKB/TrEMBL
  A0A8C0SX55_CANLF UniProtKB/TrEMBL
  A0A8C0Z002_CANLF UniProtKB/TrEMBL
  A0A8I3P3H3_CANLF UniProtKB/TrEMBL
  A0A8I3P887_CANLF UniProtKB/TrEMBL
  A0A8I3PDJ1_CANLF UniProtKB/TrEMBL
  F1PCU1 ENTREZGENE
VGNC ID VGNC:45466 ENTREZGENE