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Gene: LYN (LYN proto-oncogene, Src family tyrosine kinase) Canis lupus familiaris
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Symbol: LYN
Name: LYN proto-oncogene, Src family tyrosine kinase
Description: ENCODES a protein that exhibits enzyme binding (ortholog); ephrin receptor binding (ortholog); gamma-tubulin binding (ortholog); INVOLVED IN B cell homeostasis (ortholog); B cell receptor signaling pathway (ortholog); cellular response to extracellular stimulus (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; erythropoietin signaling pathway; ASSOCIATED WITH Cardiomegaly (ortholog); COVID-19 (ortholog); endometriosis (ortholog); FOUND IN adherens junction (ortholog); cytoplasm (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Orthologs:
Homo sapiens (human) : LYN (LYN proto-oncogene, Src family tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Lyn (LYN proto-oncogene, Src family tyrosine kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lyn (LYN proto-oncogene, Src family tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lyn (LYN proto-oncogene, Src family tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : LYN (LYN proto-oncogene, Src family tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lyn (LYN proto-oncogene, Src family tyrosine kinase)
Sus scrofa (pig) : LYN (LYN proto-oncogene, Src family tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : LYN (LYN proto-oncogene, Src family tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Lyn (LYN proto-oncogene, Src family tyrosine kinase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl297,332,684 - 7,448,507 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1297,367,617 - 7,448,862 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on LYN
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12283078
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.