KRAS (KRAS proto-oncogene, GTPase) - Rat Genome Database

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Gene: KRAS (KRAS proto-oncogene, GTPase) Canis lupus familiaris
Analyze
Symbol: KRAS
Name: KRAS proto-oncogene, GTPase
RGD ID: 12349413
Description: ENCODES a protein that exhibits GDP binding (ortholog); GMP binding (ortholog); identical protein binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cardiac muscle cell proliferation (ortholog); cell population proliferation (ortholog); PARTICIPATES IN altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH Acute Experimental Pancreatitis (ortholog); acute lymphoblastic leukemia (ortholog); acute myeloid leukemia (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GTPase KRas; K-RAS; ras p21; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12722,261,753 - 22,296,704 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2722,257,941 - 22,293,369 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2724,078,345 - 24,117,288 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02722,456,489 - 22,495,435 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2722,456,012 - 22,495,428 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12722,271,689 - 22,310,648 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02722,290,777 - 22,329,504 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02724,245,249 - 24,284,170 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (ISO)
acute lymphoblastic leukemia  (ISO)
acute myeloid leukemia  (ISO)
adenocarcinoma  (ISO)
adenoid cystic carcinoma  (ISO)
adenoma  (ISO)
anaplastic astrocytoma  (ISO)
anemia  (ISO)
angiosarcoma  (ISO)
Animal Disease Models  (ISO)
arteriovenous malformations of the brain  (ISO)
autoimmune lymphoproliferative syndrome type 4  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
breast adenocarcinoma  (ISO)
breast cancer  (ISO)
Breast Cancer, Familial  (ISO)
Breast Neoplasms  (ISO)
bronchiolo-alveolar adenocarcinoma  (ISO)
Capillary Malformation-Arteriovenous Malformation 1  (ISO)
Carcinogenesis  (ISO)
carcinoma  (ISO)
cardiofaciocutaneous syndrome  (ISO)
cardiofaciocutaneous syndrome 1  (ISO)
cardiofaciocutaneous syndrome 2  (ISO)
cardiomyopathy  (ISO)
Cecal Neoplasms  (ISO)
cholangiocarcinoma  (ISO)
chronic lymphocytic leukemia  (ISO)
chronic myelogenous leukemia, BCR-ABL1 positive  (ISO)
chronic myeloid leukemia  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
Costello syndrome  (ISO)
dilated cardiomyopathy  (ISO)
disease of cellular proliferation  (ISO)
Disease Progression  (ISO)
Encephalocraniocutaneous Lipomatosis  (ISO)
endometrial adenocarcinoma  (ISO)
endometrial carcinoma  (ISO)
endometrial hyperplasia  (ISO)
Endometrial Hyperplasia without Atypia  (ISO)
Endometrial Intraepithelial Neoplasia  (ISO)
Endometrial Neoplasms  (ISO)
Endometrioid Carcinomas  (ISO)
endometriosis  (ISO)
epidermal nevus  (ISO)
esophageal carcinoma  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Experimental Sarcoma  (ISO)
fibrillary astrocytoma  (ISO)
gallbladder cancer  (ISO)
Gallbladder Neoplasms  (ISO)
gastric adenocarcinoma  (ISO)
gastrointestinal stromal tumor  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
hepatocellular adenoma  (ISO)
hepatocellular carcinoma  (ISO)
hereditary breast ovarian cancer syndrome  (ISO)
hereditary diffuse gastric cancer  (ISO)
high grade glioma  (ISO)
Hodgkin's lymphoma  (ISO)
Hydrops Fetalis  (ISO)
hypertension  (ISO)
intellectual disability  (ISO)
intrahepatic cholangiocarcinoma  (ISO)
juvenile myelomonocytic leukemia  (ISO)
juvenile rheumatoid arthritis  (ISO)
Kidney Neoplasms  (ISO)
Klatskin's tumor  (ISO)
Leukocytosis  (ISO)
linear nevus sebaceous syndrome  (ISO)
Liver Neoplasms  (ISO)
lung adenocarcinoma  (ISO)
lung cancer  (ISO)
lung carcinoma  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (ISO)
lung sarcomatoid carcinoma  (ISO)
lung squamous cell carcinoma  (ISO)
lymphoma  (ISO)
Lynch syndrome  (ISO)
malignant astrocytoma  (ISO)
melanoma  (ISO)
Mouth Neoplasms  (ISO)
Multiple Abnormalities  (ISO)
multiple myeloma  (ISO)
muscular atrophy  (ISO)
myelodysplastic syndrome  (ISO)
myeloid neoplasm  (ISO)
myeloid sarcoma  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
neuroblastoma  (ISO)
Noonan syndrome  (ISO)
Noonan syndrome 1  (ISO)
Noonan syndrome 3  (ISO)
oculoectodermal syndrome  (ISO)
Ovarian Neoplasms  (ISO)
ovary serous adenocarcinoma  (ISO)
pancreatic adenocarcinoma  (ISO)
pancreatic cancer  (ISO)
pancreatic carcinoma  (ISO)
pancreatic ductal carcinoma  (ISO)
pancreatic mucinous cystadenoma  (ISO)
Paraproteinemias  (ISO)
Parasitic Liver Diseases  (ISO)
Penile Neoplasms  (ISO)
pilocytic astrocytoma  (ISO)
plasma cell neoplasm  (ISO)
prostate cancer  (ISO)
Prostate Cancer, Hereditary, 1  (ISO)
prostate carcinoma in situ  (ISO)
Prostatic Neoplasms  (ISO)
RASopathy  (ISO)
Recurrence  (ISO)
renal cell carcinoma  (ISO)
renal fibrosis  (ISO)
Sebaceous Nevus Syndrome and Hemimegalencephaly  (ISO)
seminoma  (ISO)
skin melanoma  (ISO)
Splenomegaly  (ISO)
squamous cell carcinoma  (ISO)
stomach cancer  (ISO)
stomach carcinoma  (ISO)
Stomach Neoplasms  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
teratoma  (ISO)
Thyroid Carcinoma, Nonmedullary 1  (ISO)
thyroid gland follicular carcinoma  (ISO)
thyroid gland medullary carcinoma  (ISO)
Thyroid Neoplasms  (ISO)
transitional cell carcinoma  (ISO)
Triple Negative Breast Neoplasms  (ISO)
urinary bladder cancer  (ISO)
Urinary Bladder Neoplasm  (ISO)
uterine cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
Uterine Neoplasms  (ISO)
Vascular Malformations  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin cytoskeleton organization  (IEA,ISO)
adipose tissue development  (IEA)
cardiac muscle cell proliferation  (ISO)
cell population proliferation  (IEA,ISO)
cellular response to gamma radiation  (IEA)
cellular senescence  (IEA)
cytokine-mediated signaling pathway  (ISO)
defense response to protozoan  (IEA)
endocytosis  (IEA)
epidermal growth factor receptor signaling pathway  (IEA)
epithelial tube branching involved in lung morphogenesis  (IEA,ISO)
female pregnancy  (ISO)
fibroblast proliferation  (IEA)
forebrain astrocyte development  (IEA,ISO)
gene expression  (IEA,ISO)
glial cell proliferation  (IEA,ISO)
homeostasis of number of cells within a tissue  (IEA,ISO)
insulin receptor signaling pathway  (IEA)
intrinsic apoptotic signaling pathway  (IEA)
liver development  (ISO)
myelination  (IEA)
myoblast proliferation  (ISO)
negative regulation of cell population proliferation  (IEA)
negative regulation of epithelial cell differentiation  (IEA,ISO)
negative regulation of gene expression  (IEA)
negative regulation of neuron apoptotic process  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
oncogene-induced cell senescence  (IEA)
positive regulation of cell migration  (IEA)
positive regulation of cell population proliferation  (IEA)
positive regulation of cellular senescence  (ISO)
positive regulation of epithelial cell proliferation  (IEA)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of fibroblast proliferation  (IEA)
positive regulation of gene expression  (IEA,ISO)
positive regulation of glial cell proliferation  (IEA,ISO)
positive regulation of JNK cascade  (IEA)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (IEA)
positive regulation of miRNA metabolic process  (IEA)
positive regulation of NF-kappaB transcription factor activity  (ISO)
positive regulation of nitric-oxide synthase activity  (ISO)
positive regulation of protein phosphorylation  (IEA)
positive regulation of protein targeting to membrane  (IEA)
positive regulation of Rac protein signal transduction  (IEA,ISO)
positive regulation of ruffle assembly  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA)
positive regulation of type II interferon production  (IEA)
positive regulation of wound healing  (IEA)
Rac protein signal transduction  (IEA,ISO)
Ras protein signal transduction  (IEA,ISO)
regulation of actin cytoskeleton organization  (IEA)
regulation of cell cycle  (IEA)
regulation of cell population proliferation  (IEA)
regulation of long-term neuronal synaptic plasticity  (IEA,ISO)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane  (IEA)
regulation of synaptic transmission, GABAergic  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA)
response to glucocorticoid  (ISO)
response to gravity  (ISO)
response to isolation stress  (ISO)
response to mineralocorticoid  (ISO)
Schwann cell development  (IEA)
signal transduction  (IEA)
skeletal muscle cell differentiation  (IEA,ISO)
small GTPase-mediated signal transduction  (IEA)
striated muscle cell differentiation  (IEA,ISO)
T cell receptor signaling pathway  (IEA)
T-helper 1 type immune response  (IEA)
type I pneumocyte differentiation  (IEA,ISO)
visual learning  (IEA,ISO)

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:1324792   PMID:9501305   PMID:22301074   PMID:22829590   PMID:22946050   PMID:24725411   PMID:27290644   PMID:28604746   PMID:30032202   PMID:33926328  


Genomics

Comparative Map Data
KRAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12722,261,753 - 22,296,704 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2722,257,941 - 22,293,369 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2724,078,345 - 24,117,288 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02722,456,489 - 22,495,435 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2722,456,012 - 22,495,428 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12722,271,689 - 22,310,648 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02722,290,777 - 22,329,504 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02724,245,249 - 24,284,170 (-)NCBIUU_Cfam_GSD_1.0
KRAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381225,205,246 - 25,250,929 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1225,205,246 - 25,250,936 (-)EnsemblGRCh38hg38GRCh38
GRCh371225,358,180 - 25,403,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361225,249,447 - 25,295,121 (-)NCBINCBI36Build 36hg18NCBI36
Build 341225,249,446 - 25,295,121NCBI
Celera1230,505,144 - 30,550,804 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1225,128,895 - 25,174,493 (-)NCBIHuRef
CHM1_11225,323,336 - 25,368,979 (-)NCBICHM1_1
T2T-CHM13v2.01225,076,496 - 25,122,152 (-)NCBIT2T-CHM13v2.0
Kras
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,162,425 - 145,197,631 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,162,425 - 145,195,965 (-)EnsemblGRCm39 Ensembl
GRCm386145,216,699 - 145,250,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,216,699 - 145,250,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv376145,165,219 - 145,198,751 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366145,173,866 - 145,207,390 (-)NCBIMGSCv36mm8
Celera6148,290,985 - 148,324,546 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.37NCBI
Kras
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84179,916,255 - 179,949,613 (-)NCBIGRCr8
mRatBN7.24178,185,418 - 178,218,484 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx4184,490,327 - 184,516,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04180,274,827 - 180,300,720 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04178,895,248 - 178,921,140 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04179,482,562 - 179,515,483 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4179,486,105 - 179,515,558 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04243,667,912 - 243,696,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44182,869,242 - 182,895,106 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14183,114,365 - 183,140,230 (-)NCBI
Celera4166,708,846 - 166,734,692 (-)NCBICelera
Cytogenetic Map4q44NCBI
Kras
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541320,298,824 - 20,328,758 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541320,298,852 - 20,328,756 (-)NCBIChiLan1.0ChiLan1.0
KRAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21071,565,722 - 71,611,563 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11271,562,118 - 71,607,959 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01261,062,689 - 61,108,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11263,679,293 - 63,724,335 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1263,679,293 - 63,724,335 (+)Ensemblpanpan1.1panPan2
Kras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494584,156,600 - 84,190,995 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365482,079,036 - 2,110,523 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365482,078,568 - 2,113,877 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl548,508,811 - 48,549,358 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1548,508,774 - 48,546,260 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2552,229,592 - 52,270,153 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KRAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11124,963,396 - 25,010,747 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1124,973,619 - 25,005,191 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606910,116,447 - 10,163,816 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kras
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475213,809,775 - 13,844,166 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475213,809,741 - 13,847,020 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KRAS
253 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 3 16 3 6 12 10 1
Low 2 5 6 6 3 6 6 8 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003433561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014108499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038438708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038438709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038438710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038513379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038513380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038513381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038577089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038577090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038577091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038577092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038641177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038641178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038641179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S42999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U62094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000010525   ⟹   ENSCAFP00000009756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2722,257,941 - 22,293,369 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000093055   ⟹   ENSCAFP00000064230
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2722,257,941 - 22,293,285 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845047195   ⟹   ENSCAFP00845037039
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2722,456,012 - 22,495,428 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845047233   ⟹   ENSCAFP00845037069
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2722,456,012 - 22,485,763 (+)Ensembl
RefSeq Acc Id: XM_038438708   ⟹   XP_038294636
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02722,456,489 - 22,485,778 (+)NCBI
RefSeq Acc Id: XM_038438709   ⟹   XP_038294637
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02722,456,493 - 22,495,435 (+)NCBI
RefSeq Acc Id: XM_038438710   ⟹   XP_038294638
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02722,456,493 - 22,495,435 (+)NCBI
RefSeq Acc Id: XM_038459914   ⟹   XP_038315842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2724,082,627 - 24,117,284 (-)NCBI
RefSeq Acc Id: XM_038459915   ⟹   XP_038315843
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2724,082,627 - 24,117,288 (-)NCBI
RefSeq Acc Id: XM_038459916   ⟹   XP_038315844
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2724,078,345 - 24,117,284 (-)NCBI
RefSeq Acc Id: XM_038459917   ⟹   XP_038315845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2724,078,345 - 24,117,284 (-)NCBI
RefSeq Acc Id: XM_038513379   ⟹   XP_038369307
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12722,271,690 - 22,300,997 (+)NCBI
RefSeq Acc Id: XM_038513380   ⟹   XP_038369308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12722,271,689 - 22,310,648 (+)NCBI
RefSeq Acc Id: XM_038513381   ⟹   XP_038369309
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12722,271,689 - 22,310,648 (+)NCBI
RefSeq Acc Id: XM_038577089   ⟹   XP_038433017
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02724,249,531 - 24,284,166 (-)NCBI
RefSeq Acc Id: XM_038577090   ⟹   XP_038433018
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02724,249,531 - 24,284,170 (-)NCBI
RefSeq Acc Id: XM_038577091   ⟹   XP_038433019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02724,245,249 - 24,284,166 (-)NCBI
RefSeq Acc Id: XM_038577092   ⟹   XP_038433020
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02724,245,249 - 24,284,166 (-)NCBI
RefSeq Acc Id: XM_038641177   ⟹   XP_038497105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02722,290,777 - 22,319,852 (+)NCBI
RefSeq Acc Id: XM_038641178   ⟹   XP_038497106
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02722,290,781 - 22,329,504 (+)NCBI
RefSeq Acc Id: XM_038641179   ⟹   XP_038497107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02722,290,781 - 22,329,504 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038294636 (Get FASTA)   NCBI Sequence Viewer  
  XP_038294637 (Get FASTA)   NCBI Sequence Viewer  
  XP_038294638 (Get FASTA)   NCBI Sequence Viewer  
  XP_038315842 (Get FASTA)   NCBI Sequence Viewer  
  XP_038315843 (Get FASTA)   NCBI Sequence Viewer  
  XP_038315844 (Get FASTA)   NCBI Sequence Viewer  
  XP_038315845 (Get FASTA)   NCBI Sequence Viewer  
  XP_038369307 (Get FASTA)   NCBI Sequence Viewer  
  XP_038369308 (Get FASTA)   NCBI Sequence Viewer  
  XP_038369309 (Get FASTA)   NCBI Sequence Viewer  
  XP_038433017 (Get FASTA)   NCBI Sequence Viewer  
  XP_038433018 (Get FASTA)   NCBI Sequence Viewer  
  XP_038433019 (Get FASTA)   NCBI Sequence Viewer  
  XP_038433020 (Get FASTA)   NCBI Sequence Viewer  
  XP_038497105 (Get FASTA)   NCBI Sequence Viewer  
  XP_038497106 (Get FASTA)   NCBI Sequence Viewer  
  XP_038497107 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC13248 (Get FASTA)   NCBI Sequence Viewer  
  AAD13827 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000064230.2
  ENSCAFP00000069278.1
  ENSCAFP00000069296.1
  ENSCAFP00030030466.1
  ENSCAFP00030030482.1
  ENSCAFP00030030496.1
  ENSCAFP00030030518.1
  ENSCAFP00040036190.1
  ENSCAFP00040036242.1
  ENSCAFP00040036256.1
  ENSCAFP00040036270.1
  ENSCAFP00040037673.1
  ENSCAFP00845037039
  ENSCAFP00845037039.1
  ENSCAFP00845037069
  ENSCAFP00845037069.1
  ENSCAFP00845041215.1
RefSeq Acc Id: ENSCAFP00000009756   ⟸   ENSCAFT00000010525
RefSeq Acc Id: ENSCAFP00000064230   ⟸   ENSCAFT00000093055
RefSeq Acc Id: XP_038369309   ⟸   XM_038513381
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038369308   ⟸   XM_038513380
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038369307   ⟸   XM_038513379
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038497105   ⟸   XM_038641177
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038497107   ⟸   XM_038641179
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038497106   ⟸   XM_038641178
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038294636   ⟸   XM_038438708
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P231 (UniProtKB/TrEMBL),   A0A8I3PZB5 (UniProtKB/TrEMBL),   A0A8C0KJX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038294638   ⟸   XM_038438710
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KJX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038294637   ⟸   XM_038438709
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KKR3 (UniProtKB/TrEMBL),   A0A8C0TKU0 (UniProtKB/TrEMBL),   A0A8I3PQK0 (UniProtKB/TrEMBL),   A0A8C0K1I4 (UniProtKB/TrEMBL),   A0A8C0TJS5 (UniProtKB/TrEMBL),   A0A8I3Q1I3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315844   ⟸   XM_038459916
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KKR3 (UniProtKB/TrEMBL),   A0A8C0TKU0 (UniProtKB/TrEMBL),   A0A8I3PQK0 (UniProtKB/TrEMBL),   A0A8C0K1I4 (UniProtKB/TrEMBL),   A0A8C0TJS5 (UniProtKB/TrEMBL),   A0A8I3Q1I3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315845   ⟸   XM_038459917
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KJX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315843   ⟸   XM_038459915
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P231 (UniProtKB/TrEMBL),   A0A8I3PZB5 (UniProtKB/TrEMBL),   A0A8C0KJX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315842   ⟸   XM_038459914
- Peptide Label: isoform X1
- UniProtKB: A0A8C0P231 (UniProtKB/TrEMBL),   A0A8I3PZB5 (UniProtKB/TrEMBL),   A0A8C0KJX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433019   ⟸   XM_038577091
- Peptide Label: isoform X2
- UniProtKB: A0A8C0K1I4 (UniProtKB/TrEMBL),   A0A8C0KKR3 (UniProtKB/TrEMBL),   A0A8C0TJS5 (UniProtKB/TrEMBL),   A0A8C0TKU0 (UniProtKB/TrEMBL),   A0A8I3PQK0 (UniProtKB/TrEMBL),   A0A8I3Q1I3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433020   ⟸   XM_038577092
- Peptide Label: isoform X3
- UniProtKB: A0A8C0KJX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433018   ⟸   XM_038577090
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJX6 (UniProtKB/TrEMBL),   A0A8C0P231 (UniProtKB/TrEMBL),   A0A8I3PZB5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433017   ⟸   XM_038577089
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KJX6 (UniProtKB/TrEMBL),   A0A8C0P231 (UniProtKB/TrEMBL),   A0A8I3PZB5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845037069   ⟸   ENSCAFT00845047233
RefSeq Acc Id: ENSCAFP00845037039   ⟸   ENSCAFT00845047195


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011428 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00000031029 UniProtKB/TrEMBL
  ENSCAFG00030019018 UniProtKB/TrEMBL
  ENSCAFG00040022325 UniProtKB/TrEMBL
  ENSCAFG00040023230 UniProtKB/TrEMBL
  ENSCAFG00845026771 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFG00845029661 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000093055.2 UniProtKB/TrEMBL
  ENSCAFT00000105346.1 UniProtKB/TrEMBL
  ENSCAFT00000106371.1 UniProtKB/TrEMBL
  ENSCAFT00030034938.1 UniProtKB/TrEMBL
  ENSCAFT00030034957.1 UniProtKB/TrEMBL
  ENSCAFT00030034970.1 UniProtKB/TrEMBL
  ENSCAFT00030034998.1 UniProtKB/TrEMBL
  ENSCAFT00040041485.1 UniProtKB/TrEMBL
  ENSCAFT00040041547.1 UniProtKB/TrEMBL
  ENSCAFT00040041565.1 UniProtKB/TrEMBL
  ENSCAFT00040041580.1 UniProtKB/TrEMBL
  ENSCAFT00040043177.1 UniProtKB/TrEMBL
  ENSCAFT00845047195 ENTREZGENE
  ENSCAFT00845047195.1 UniProtKB/TrEMBL
  ENSCAFT00845047233 ENTREZGENE
  ENSCAFT00845047233.1 UniProtKB/TrEMBL
  ENSCAFT00845052525.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
  Small_GTPase_Ras-type UniProtKB/TrEMBL
NCBI Gene KRAS ENTREZGENE
PANTHER GTPASE HRAS UniProtKB/TrEMBL
  GTPASE KRAS UniProtKB/TrEMBL
  GTPASE KRAS UniProtKB/TrEMBL
  PTHR24070 UniProtKB/TrEMBL
  RAS-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0K1I4 ENTREZGENE
  A0A8C0KJX6 ENTREZGENE
  A0A8C0KKR3 ENTREZGENE
  A0A8C0NW36_CANLF UniProtKB/TrEMBL
  A0A8C0NWF2_CANLF UniProtKB/TrEMBL
  A0A8C0P231 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TF30_CANLF UniProtKB/TrEMBL
  A0A8C0TJS5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TKU0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z4F5_CANLF UniProtKB/TrEMBL
  A0A8I3PQK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PZB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3Q1I3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42508 ENTREZGENE