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Gene: SRC (SRC proto-oncogene, non-receptor tyrosine kinase) Canis lupus familiaris
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Symbol: SRC
Name: SRC proto-oncogene, non-receptor tyrosine kinase
Description: ENCODES a protein that exhibits BMP receptor binding (ortholog); cell adhesion molecule binding (ortholog); connexin binding (ortholog); INVOLVED IN positive regulation of epithelial cell migration; positive regulation of lamellipodium morphogenesis; activation of protein kinase B activity (ortholog); PARTICIPATES IN dopamine signaling pathway; E-cadherin signaling pathway; eicosanoid signaling pathway; ASSOCIATED WITH autosomal recessive polycystic kidney disease (ortholog); brain ischemia (ortholog); Breast Neoplasms (ortholog); FOUND IN actin filament (ortholog); caveola (ortholog); cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: proto-oncogene tyrosine-protein kinase Src; src oncogene; tyrosine protein kinase pp60-c-src; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Orthologs:
Homo sapiens (human) : SRC (SRC proto-oncogene, non-receptor tyrosine kinase)  HGNC  Alliance
Mus musculus (house mouse) : Src (Rous sarcoma oncogene)  MGI  Alliance
Rattus norvegicus (Norway rat) : Src (SRC proto-oncogene, non-receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Src (SRC proto-oncogene, non-receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : SRC (SRC proto-oncogene, non-receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Src (SRC proto-oncogene, non-receptor tyrosine kinase)
Sus scrofa (pig) : SRC (SRC proto-oncogene, non-receptor tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : SRC (SRC proto-oncogene, non-receptor tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Src (SRC proto-oncogene, non-receptor tyrosine kinase)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2425,999,048 - 26,018,077 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12425,982,499 - 26,019,748 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on SRC
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12080083
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.