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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of cytokine-mediated signaling pathway
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Accession:GO:0001959 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
Synonyms:exact_synonym: regulation of cytokine and chemokine mediated signaling pathway;   regulation of cytokine mediated signalling pathway


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regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule involved_in ISO
ISS		 (MGI:3614932|PMID:16390867) RGD PMID:16390867 PMID:16390867 MGI:3614932, RGD:8553244 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 involved_in ISO (PMID:10383454) RGD PMID:10383454 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 involved_in ISO (PMID:10383454) RGD PMID:10383454 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl5 C-C motif chemokine ligand 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO
IEA		 (PMID:18645041)
GO_REF:0000107		 RGD
Ensembl		 PMID:18645041 GO_REF:0000107 NCBI chr 5:153,209,053...153,251,632
Ensembl chr 5:153,209,053...153,251,632 		JBrowse link
G Rnf113a1 ring finger protein 113A1 involved_in ISO (PMID:28978524) RGD PMID:28978524 NCBI chr  X:116,428,037...116,429,164
Ensembl chr  X:116,427,684...116,433,762 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr11:10,580,863...11,621,672
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3510267|PMID:15337790)		 Ensembl
RGD		 PMID:15337790 GO_REF:0000107 MGI:3510267 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (PMID:18829537) RGD PMID:18829537 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO
IEA		 (PMID:18829537)
GO_REF:0000107		 RGD
Ensembl		 PMID:18829537 GO_REF:0000107 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
negative regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 acts_upstream_of_or_within ISO MGI:2180364 (MGI:3703676|PMID:12388746) RGD PMID:12388746 MGI:3703676 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ecm1 extracellular matrix protein 1 acts_upstream_of_or_within ISO (MGI:4887510|PMID:21217760) RGD PMID:21217760 MGI:4887510 NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938 		JBrowse link
G Il36rn interleukin 36 receptor antagonist involved_in ISO (PMID:23147407) RGD PMID:23147407 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:30106099) RGD PMID:30106099 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir29b1 microRNA 29b-1 acts_upstream_of ISO (PMID:23729669) RGD PMID:23729669 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 acts_upstream_of ISO (PMID:23729669) RGD PMID:23729669 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Palm3 paralemmin 3 involved_in ISO
IBA		 (PMID:21187075)
PMID:21873635		 RGD PMID:21187075 PMID:21873635 RGD:13792537 NCBI chr19:24,121,984...24,126,079
Ensembl chr19:24,122,239...24,130,448 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO		 GO_REF:0000024
(MGI:2386427|PMID:11201744)		 UniProt
RGD		 PMID:11201744 GO_REF:0000024 MGI:2386427 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F IMP hepatocyte growth factor/Met signaling RGD PMID:16415345 RGD:1642742 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023 		JBrowse link
G Sigirr single Ig and TIR domain containing involved_in ISS
ISO		 GO_REF:0000024
(MGI:2673012|PMID:12925853)		 HGNC-UCL
RGD		 PMID:12925853 GO_REF:0000024 MGI:2673012 NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269 		JBrowse link
negative regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r2 interleukin 1 receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
PR:000045525 (MGI:5468848|PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rn interleukin 1 receptor antagonist involved_in ISO
IBA		 (PMID:2137200), (PMID:2139180)
PMID:21873635		 RGD PMID:2137200 PMID:2139180 PMID:21873635 RGD:13792537 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 involved_in ISO (MGI:5795829|PMID:11159963) RGD PMID:11159963 MGI:5795829 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mir21 microRNA 21 acts_upstream_of_or_within ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir27a microRNA 27a involved_in ISO UniProtKB:P01584 (PMID:25327529) RGD PMID:25327529 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO
IBA		 (PMID:29395066)
(MGI:6120140|PMID:29395066)
PMID:21873635		 RGD PMID:29395066 PMID:21873635 MGI:6120140, RGD:13792537 NCBI chr19:28,236,713...28,279,815
Ensembl chr19:28,236,713...28,279,815 		JBrowse link
negative regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:6706628|PMID:32424362)		 UniProt
RGD		 PMID:32424362 GO_REF:0000024 MGI:6706628 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
negative regulation of interleukin-2-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3691503|PMID:11909529)
(PMID:11909529)		 UniProt
RGD		 PMID:11909529 GO_REF:0000024 MGI:3691503 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS		 (PMID:17210636)
(MGI:5493214|PMID:17210636)
GO_REF:0000024		 RGD
UniProt		 PMID:17210636 GO_REF:0000024 MGI:5493214 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO (PMID:8353278) RGD PMID:8353278 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Mir125a microRNA 125a acts_upstream_of_or_within ISO UniProtKB:P05231 (PMID:30670152) RGD PMID:30670152 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir125b1 microRNA 125b-1 involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052 		JBrowse link
G Mir125b2 microRNA 125b-2 involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr11:16,245,620...16,245,707 JBrowse link
G Mir26a microRNA 26a involved_in ISO (PMID:23389848) RGD PMID:23389848 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir98 microRNA 98 involved_in ISO UniProtKB:P05231 (PMID:26587789), (PMID:31886314) RGD PMID:26587789 PMID:31886314 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mir99a microRNA 99a involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Mirlet7a1 microRNA let-7a-1 involved_in ISO (PMID:19878981) RGD PMID:19878981 NCBI chr17:16,113,766...16,113,859
Ensembl chr17:16,113,768...16,113,867 		JBrowse link
G Mirlet7c1 microRNA let-7c-1 involved_in ISO (PMID:26455324) RGD PMID:26455324 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265 		JBrowse link
G Mirlet7c2 microRNA let7c-2 involved_in ISO (PMID:19878981) RGD PMID:19878981 NCBI chr 7:116,803,771...116,803,865
Ensembl chr 7:116,803,771...116,803,865 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS		 (PMID:12359225)
(MGI:4941441|PMID:20484139)
GO_REF:0000024		 RGD
UniProt		 PMID:12359225 PMID:20484139 GO_REF:0000024 MGI:4941441 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of Kit signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rabgef1 RAB guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3051384 (MGI:3620385|PMID:16533754) RGD PMID:16533754 MGI:3620385 NCBI chr12:26,459,190...26,503,790
Ensembl chr12:26,460,175...26,503,744 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO		 GO_REF:0000107
GO:1990782 (MGI:3041996|PMID:14612394)		 Ensembl
RGD		 PMID:14612394 GO_REF:0000107 MGI:3041996 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
negative regulation of macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3629372|PMID:16705167)		 UniProt
RGD		 PMID:16705167 GO_REF:0000024 MGI:3629372 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO (MGI:3831067|PMID:19100238) RGD PMID:19100238 MGI:3831067 NCBI chr14:21,950,466...21,981,395
Ensembl chr14:21,952,496...21,981,245 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708) RGD PMID:33097708 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
negative regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO		 GO_REF:0000024
(PMID:10604883)		 UniProt
RGD		 PMID:10604883 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Apoa1 apolipoprotein A1 involved_in ISO
IEA		 (PMID:21571275)
GO_REF:0000107		 RGD
Ensembl		 PMID:21571275 GO_REF:0000107 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 involved_in ISO (PMID:25193116) RGD PMID:25193116 NCBI chr17:73,031,891...73,135,173
Ensembl chr17:73,035,045...73,135,337 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19781631) RGD PMID:19781631 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
ISS		 (PMID:19657094)
GO_REF:0000024		 RGD
UniProt		 PMID:19657094 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (MGI:6148454|PMID:22424771) RGD PMID:22424771 MGI:6148454 NCBI chr10:54,637,360...54,640,542
Ensembl chr10:54,637,455...54,640,650 		JBrowse link
G Hist2h2be histone cluster 2 H2B family member E involved_in ISO (PMID:11859126) RGD PMID:11859126 NCBI chr 2:183,780,449...183,783,030 JBrowse link
G Mir152 microRNA 152 involved_in ISO (PMID:24813629) RGD PMID:24813629 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr 2:31,507,423...31,559,098
Ensembl chr 2:31,507,424...31,570,542 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5617337|PMID:24440909)		 Ensembl
RGD		 PMID:24440909 GO_REF:0000107 MGI:5617337 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO
IEA		 (MGI:5707586|PMID:18972444)
GO_REF:0000107		 RGD
Ensembl		 PMID:18972444 GO_REF:0000107 MGI:5707586 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO MGI:5441750 (MGI:5546581|PMID:23950925)
(PMID:24113711)		 RGD PMID:23950925 PMID:24113711 MGI:5546581 NCBI chr 1:202,230,034...202,242,900
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO (MGI:4453084|PMID:20054338) RGD PMID:20054338 MGI:4453084 NCBI chr 7:8,546,312...8,559,838
Ensembl chr 7:8,546,312...8,559,808 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta acts_upstream_of ISO UniProtKB:P01375 (PMID:28159925) RGD PMID:28159925 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3530208|PMID:15696169)		 UniProt
RGD		 PMID:15696169 GO_REF:0000024 MGI:3530208 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
ISS		 (PMID:18450452)
GO_REF:0000024		 RGD
UniProt		 PMID:18450452 GO_REF:0000024 NCBI chr10:67,740,711...67,803,694
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Traip TRAF-interacting protein involved_in ISO (PMID:19151749) RGD PMID:19151749 NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638 		JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO (PMID:11865055) RGD PMID:11865055 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific acts_upstream_of_or_within ISO MGI:3828307 (MGI:3821394|PMID:19060901) RGD PMID:19060901 MGI:3821394 NCBI chr 2:175,138,391...175,178,280
Ensembl chr 2:175,138,403...175,178,282 		JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219
Ensembl chr 7:8,391,397...8,396,829 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 involved_in ISO (PMID:23386060) RGD PMID:23386060 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (PMID:27782195) RGD PMID:27782195 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier involved_in ISO (PMID:28724761) RGD PMID:28724761 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23633945) RGD PMID:23633945 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20434986)
(MGI:4454346|PMID:20434986)		 RGD PMID:20434986 MGI:4454346 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A involved_in ISO (PMID:30078389) RGD PMID:30078389 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA		 (PMID:30078389)
GO_REF:0000107		 RGD
Ensembl		 PMID:30078389 GO_REF:0000107 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISO
ISS		 (PMID:11909529)
(MGI:3691503|PMID:11909529), (MGI:5493216|PMID:12138178)
GO_REF:0000024		 RGD
UniProt		 PMID:11909529 PMID:12138178 GO_REF:0000024 MGI:3691503 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:29670289)
(MGI:5521417|PMID:23972988)		 RGD PMID:23972988 PMID:29670289 MGI:5521417 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 involved_in ISO (PMID:28165510)
(MGI:6508512|PMID:28165510)		 RGD PMID:28165510 MGI:6508512 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO MGI:3052754 (MGI:3834787|PMID:18724932) RGD PMID:18724932 MGI:3834787 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Ttll12 tubulin tyrosine ligase like 12 involved_in ISO (PMID:28011935) RGD PMID:28011935 NCBI chr 7:114,731,890...114,751,237
Ensembl chr 7:114,731,892...114,751,356 		JBrowse link
G Usp18 ubiquitin specific peptidase 18 involved_in ISO (PMID:28165510) RGD PMID:28165510 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144 		JBrowse link
G Ythdf2 YTH N6-methyladenosine RNA binding protein F2 involved_in ISO (PMID:30559377) RGD PMID:30559377 NCBI chr 5:144,381,426...144,407,126
Ensembl chr 5:144,381,431...144,408,144 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 involved_in ISO (MGI:6316470|PMID:30591559) RGD PMID:30591559 MGI:6316470 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
negative regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO (PMID:16709924) RGD PMID:16709924 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:11679576) RGD PMID:11679576 NCBI chr10:10,855,510...10,880,175
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Otop1 otopetrin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5750846|PMID:24379350)		 UniProt
RGD		 PMID:24379350 GO_REF:0000024 MGI:5750846 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300)
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 MGI:5905929 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:21268089) RGD PMID:21268089 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5493216|PMID:12138178)		 UniProt
RGD		 PMID:12138178 GO_REF:0000024 MGI:5493216 NCBI chr18:61,229,012...61,294,662
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
positive regulation of C-C chemokine receptor CCR7 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:11602640) RGD PMID:11602640 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 acts_upstream_of ISO (PMID:17178876) RGD PMID:17178876 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of
involved_in		 ISO
IEA		 (PMID:17178876)
GO_REF:0000107		 RGD
Ensembl		 PMID:17178876 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
positive regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:18840707) RGD PMID:18840707 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:4419085|PMID:12782713)
PMID:21873635
(PMID:12782713)		 BHF-UCL
RGD		 PMID:12782713 PMID:21873635 GO_REF:0000024 MGI:4419085, RGD:13792537 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
ISS		 (PMID:18840707)
GO_REF:0000024		 RGD
UniProt		 PMID:18840707 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Il7 interleukin 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11418668)		 Ensembl
RGD		 PMID:11418668 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 acts_upstream_of_or_within ISO (MGI:5308511|PMID:22073305) RGD PMID:22073305 MGI:5308511 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070 (MGI:2176424|PMID:11894097) RGD PMID:11894097 MGI:2176424 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Trim44 tripartite motif-containing 44 involved_in ISO
IEA		 (PMID:23460740)
GO_REF:0000107		 RGD
Ensembl		 PMID:23460740 GO_REF:0000107 NCBI chr 3:88,597,962...88,729,085
Ensembl chr 3:88,592,719...88,729,188 		JBrowse link
G Tslp thymic stromal lymphopoietin involved_in ISO
IBA		 (PMID:11418668)
PMID:21873635		 RGD PMID:11418668 PMID:21873635 RGD:13792537 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
positive regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1r1 interleukin 1 receptor type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
PR:000045524 (MGI:5468848|PMID:23395675)		 Ensembl
RGD		 PMID:23395675 GO_REF:0000107 MGI:5468848 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
positive regulation of interleukin-17-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim32 tripartite motif-containing 32 acts_upstream_of_or_within ISO (MGI:4453084|PMID:20054338) RGD PMID:20054338 MGI:4453084 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
positive regulation of interleukin-18-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp4 caspase 4 involved_in ISO (PMID:33377178)
(MGI:6259277|PMID:30392956)		 RGD PMID:30392956 PMID:33377178 MGI:6259277 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5704237|PMID:26638072), (MGI:6259277|PMID:30392956), (MGI:6833928|PMID:34678144)
(PMID:33377178), (PMID:34161762)		 UniProt
RGD		 PMID:26638072 PMID:30392956 PMID:33377178 PMID:34161762 PMID:34678144 GO_REF:0000024 MGI:5704237 MGI:6259277 MGI:6833928 NCBI chr 1:196,004,854...196,011,615
Ensembl chr 1:196,004,953...196,011,113 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:22685567)
(MGI:5488868|PMID:22685567)		 RGD PMID:22685567 MGI:5488868 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
positive regulation of interleukin-4-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO		 GO_REF:0000024
(MGI:5660125|PMID:26124135)		 UniProt
RGD		 PMID:26124135 GO_REF:0000024 MGI:5660125 NCBI chr10:100,359,942...100,376,130
Ensembl chr10:100,359,943...100,376,041 		JBrowse link
G Parp14 poly (ADP-ribose) polymerase family, member 14 involved_in ISO (PMID:27796300)
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 MGI:5905929 NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916 		JBrowse link
positive regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qtnf4 C1q and TNF related 4 involved_in ISO (PMID:21658842) RGD PMID:21658842 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:11060035) RGD PMID:11060035 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (PMID:31827280)
(MGI:6401044|PMID:31827281)		 RGD PMID:31827280 PMID:31827281 MGI:6401044 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
positive regulation of macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1 colony stimulating factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19100238)		 Ensembl
RGD		 PMID:19100238 GO_REF:0000107 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
positive regulation of macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule involved_in ISO (PMID:19665027) RGD PMID:19665027 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 involved_in ISO (PMID:19665027) RGD PMID:19665027 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
positive regulation of prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crebrf CREB3 regulatory factor acts_upstream_of_or_within ISO (MGI:5466657|PMID:23071095) RGD PMID:23071095 MGI:5466657 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
positive regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 ADAM metallopeptidase domain 17 involved_in ISO (PMID:24813629) RGD PMID:24813629 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Casp1 caspase 1 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cpne1 copine 1 involved_in ISO
IBA		 (PMID:14674885)
PMID:21873635		 RGD PMID:14674885 PMID:21873635 RGD:13792537 NCBI chr 3:144,587,548...144,629,603
Ensembl chr 3:144,588,995...144,598,636 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO UniProtKB:Q9HC29 (PMID:24790089) RGD PMID:24790089 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:6391873|PMID:22733818) RGD PMID:22733818 MGI:6391873 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
ISS		 (PMID:23453807)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:23453807 GO_REF:0000024 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rbm12 RNA binding motif protein 12 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:144,587,548...144,629,950
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:6271183|PMID:30439713) RGD PMID:30439713 MGI:6271183 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (MGI:5616328|PMID:11374864) RGD PMID:11374864 MGI:5616328 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Trim32 tripartite motif-containing 32 acts_upstream_of_or_within ISO (MGI:4453084|PMID:20054338) RGD PMID:20054338 MGI:4453084 NCBI chr 5:79,005,139...79,016,615
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:26707646) RGD PMID:26707646 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO (PMID:21109225) RGD PMID:21109225 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (MGI:5792628|PMID:27129230)
(PMID:24882218)		 RGD PMID:24882218 PMID:27129230 MGI:5792628 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:3718275 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Irf7 interferon regulatory factor 7 acts_upstream_of_or_within ISO (MGI:3718275|PMID:17618271) RGD PMID:17618271 MGI:3718275 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor acts_upstream_of_or_within ISO (MGI:5432265|PMID:22745163) RGD PMID:22745163 MGI:5432265 NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16127453), (PMID:20451243) RGD PMID:16127453 PMID:20451243 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mmp12 matrix metallopeptidase 12 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5583923|PMID:24784232)		 Ensembl
RGD		 PMID:24784232 GO_REF:0000107 MGI:5583923 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403) RGD PMID:20061403 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Rbm47 RNA binding motif protein 47 involved_in ISO (PMID:34160127) RGD PMID:34160127 NCBI chr14:42,053,290...42,191,572
Ensembl chr14:42,154,142...42,189,431 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO
ISS		 (PMID:28273161)
GO_REF:0000024		 RGD
UniProt		 PMID:28273161 GO_REF:0000024 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378)
(MGI:6827194|PMID:23910378)		 RGD PMID:23910378 MGI:6827194 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (MGI:5792628|PMID:27129230) RGD PMID:27129230 MGI:5792628 NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892 		JBrowse link
G Trim41 tripartite motif-containing 41 involved_in ISO (PMID:29760876) RGD PMID:29760876 NCBI chr10:33,175,213...33,186,472
Ensembl chr10:33,175,213...33,186,694 		JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:29426904)
(MGI:6119245|PMID:29426904)		 RGD PMID:29426904 MGI:6119245 NCBI chr12:19,544,913...19,567,324
Ensembl chr12:19,551,521...19,567,462 		JBrowse link
G Trim6 tripartite motif containing 6 involved_in ISO (PMID:24882218)
(MGI:5645191|PMID:24882218)		 RGD PMID:24882218 MGI:5645191 NCBI chr 1:158,683,746...158,696,936
Ensembl chr 1:158,683,746...158,696,914 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K involved_in ISO (PMID:24882218) RGD PMID:24882218 NCBI chr14:42,658,016...42,718,899
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked involved_in ISO (PMID:31534008) RGD PMID:31534008 NCBI chr  X:15,123,642...15,126,855
Ensembl chr  X:15,124,596...15,125,912 		JBrowse link
G Usp29 ubiquitin specific peptidase 29 involved_in ISO (MGI:6761183|PMID:32457395) RGD PMID:32457395 MGI:6761183 NCBI chr 1:66,874,216...67,097,731
Ensembl chr 1:66,874,017...67,097,686 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:19399181) RGD PMID:19399181 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
(MGI:3718275|PMID:17618271)
PMID:21873635		 InterPro
RGD		 PMID:17618271 PMID:21873635 GO_REF:0000002 MGI:3718275, RGD:13792537 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
positive regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (MGI:3807609|PMID:18641331) RGD PMID:18641331 MGI:3807609 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:16888103)
(MGI:3656111|PMID:16888103)		 RGD PMID:16888103 MGI:3656111 NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Med1 mediator complex subunit 1 acts_upstream_of_or_within ISO MGI:2176946|MGI:3511276 (MGI:3798012|PMID:18339625) RGD PMID:18339625 MGI:3798012 NCBI chr10:83,145,538...83,189,260
Ensembl chr10:83,145,568...83,189,299 		JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 involved_in ISO (PMID:20061403), (PMID:20639463) RGD PMID:20061403 PMID:20639463 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 involved_in ISO
IBA		 (PMID:27796300)
PMID:21873635
(MGI:5905929|PMID:27796300)		 RGD PMID:27796300 PMID:21873635 MGI:5905929, RGD:13792537 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Txk TXK tyrosine kinase involved_in ISO (PMID:11859127) RGD PMID:11859127 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448 		JBrowse link
regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vrk2 VRK serine/threonine kinase 2 involved_in ISO (PMID:18286207) RGD PMID:18286207 NCBI chr14:100,313,771...100,434,605
Ensembl chr14:100,313,601...100,434,527 		JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6394181|PMID:31630209)		 UniProt
RGD		 PMID:31630209 GO_REF:0000024 MGI:6394181 NCBI chr 3:161,993,351...162,009,297
Ensembl chr 3:161,993,351...162,003,870 		JBrowse link
regulation of macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:4437182|PMID:20060382)		 Ensembl
RGD		 PMID:20060382 GO_REF:0000107 MGI:4437182 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5912943|PMID:28701375)
(PMID:26997266), (PMID:27458237), (PMID:27591049)		 UniProt
RGD		 PMID:26997266 PMID:27458237 PMID:27591049 PMID:28701375 GO_REF:0000024 MGI:5912943 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in ISO
IEA		 (PMID:15701637)
GO_REF:0000107		 RGD
Ensembl		 PMID:15701637 GO_REF:0000107 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Nkiras1 NFKB inhibitor interacting Ras-like 1 acts_upstream_of_or_within ISO MGI:1314884|MGI:1919216 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr15:7,492,806...7,503,828
Ensembl chr15:7,493,531...7,503,854 		JBrowse link
G Nkiras2 NFKB inhibitor interacting Ras-like 2 acts_upstream_of_or_within ISO MGI:1314884|MGI:1916971 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr10:85,554,704...85,562,072
Ensembl chr10:85,557,944...85,562,072 		JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO
IBA		 (PMID:26997266)
PMID:21873635
(MGI:5804663|PMID:27523608), (MGI:6192867|PMID:29950720)		 RGD PMID:26997266 PMID:27523608 PMID:29950720 PMID:21873635 MGI:5804663 MGI:6192867, RGD:13792537 NCBI chr 2:78,290,437...78,316,633
Ensembl chr 2:78,290,959...78,316,422 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:14730312) RGD PMID:14730312 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sharpin SHANK-associated RH domain interactor involved_in ISO
ISS		 (PMID:21455173)
GO_REF:0000024
(MGI:4947438|PMID:21455180), (MGI:4947439|PMID:21455173)		 RGD
UniProt		 PMID:21455173 PMID:21455180 GO_REF:0000024 MGI:4947438 MGI:4947439 NCBI chr 7:108,070,681...108,075,012
Ensembl chr 7:108,070,687...108,074,955 		JBrowse link
G Spata2 spermatogenesis associated 2 involved_in ISO
ISS
IBA		 (PMID:27307491), (PMID:27458237), (PMID:27545878), (PMID:27591049)
(MGI:5912943|PMID:28701375)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:27307491 PMID:27458237 PMID:27545878 PMID:27591049 PMID:28701375 More... GO_REF:0000024 MGI:5912943, RGD:13792537 NCBI chr 3:156,202,962...156,213,283
Ensembl chr 3:156,202,967...156,211,705 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
ISS
IMP		 (PMID:20577214)
GO_REF:0000107
GO_REF:0000024
PMID:28284343		 RGD
Ensembl
UniProt		 PMID:20577214 PMID:28284343 GO_REF:0000024 GO_REF:0000107, RGD:14397556 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:19151749)
GO_REF:0000107		 RGD
Ensembl		 PMID:19151749 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A acts_upstream_of_or_within ISO MGI:1916971|MGI:1919216 (MGI:6274062|PMID:25220458) RGD PMID:25220458 MGI:6274062 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within ISO (PMID:16280321) RGD PMID:16280321 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
regulation of type II interferon-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc37 cell division cycle 37, HSP90 cochaperone acts_upstream_of_or_within ISO (PMID:16280321) RGD PMID:16280321 NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    cellular process 17330
      signal transduction 7035
        regulation of signal transduction 3136
          regulation of cytokine-mediated signaling pathway 149
            negative regulation of cytokine-mediated signaling pathway + 80
            positive regulation of cytokine-mediated signaling pathway + 58
            regulation of Kit signaling pathway + 2
            regulation of chemokine-mediated signaling pathway + 10
            regulation of interleukin-1-mediated signaling pathway + 9
            regulation of interleukin-17-mediated signaling pathway + 1
            regulation of interleukin-18-mediated signaling pathway + 4
            regulation of interleukin-2-mediated signaling pathway + 1
            regulation of interleukin-27-mediated signaling pathway + 0
            regulation of interleukin-35-mediated signaling pathway + 0
            regulation of interleukin-4-mediated signaling pathway + 3
            regulation of interleukin-6-mediated signaling pathway + 14
            regulation of macrophage colony-stimulating factor signaling pathway + 4
            regulation of macrophage migration inhibitory factor signaling pathway + 3
            regulation of prolactin signaling pathway + 1
            regulation of tumor necrosis factor-mediated signaling pathway + 44
            regulation of type I interferon-mediated signaling pathway + 39
            regulation of type II interferon-mediated signaling pathway + 13
Path 2
Term Annotations click to browse term
  biological_process 19738
    response to stimulus 10453
      response to chemical 6038
        response to organic substance 3728
          response to cytokine 1184
            cellular response to cytokine stimulus 1045
              cytokine-mediated signaling pathway 454
                regulation of cytokine-mediated signaling pathway 149
                  negative regulation of cytokine-mediated signaling pathway + 80
                  positive regulation of cytokine-mediated signaling pathway + 58
                  regulation of Kit signaling pathway + 2
                  regulation of chemokine-mediated signaling pathway + 10
                  regulation of interleukin-1-mediated signaling pathway + 9
                  regulation of interleukin-17-mediated signaling pathway + 1
                  regulation of interleukin-18-mediated signaling pathway + 4
                  regulation of interleukin-2-mediated signaling pathway + 1
                  regulation of interleukin-27-mediated signaling pathway + 0
                  regulation of interleukin-35-mediated signaling pathway + 0
                  regulation of interleukin-4-mediated signaling pathway + 3
                  regulation of interleukin-6-mediated signaling pathway + 14
                  regulation of macrophage colony-stimulating factor signaling pathway + 4
                  regulation of macrophage migration inhibitory factor signaling pathway + 3
                  regulation of prolactin signaling pathway + 1
                  regulation of tumor necrosis factor-mediated signaling pathway + 44
                  regulation of type I interferon-mediated signaling pathway + 39
                  regulation of type II interferon-mediated signaling pathway + 13
paths to the root