CCL17 (C-C motif chemokine ligand 17) - Rat Genome Database

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Gene: CCL17 (C-C motif chemokine ligand 17) Canis lupus familiaris
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Symbol: CCL17
Name: C-C motif chemokine ligand 17
RGD ID: 12077453
Description: ENCODES a protein that exhibits CCR4 chemokine receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); killing of cells of another organism (ortholog); negative regulation of myoblast differentiation (ortholog); PARTICIPATES IN interleukin-4 signaling pathway; ASSOCIATED WITH allergic bronchopulmonary aspergillosis (ortholog); allergic contact dermatitis (ortholog); allergic disease (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred); INTERACTS WITH cannabidiol; luteolin
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-C motif chemokine 17; CC chemokine TARC; chemokine (C-C motif) ligand 17; small-inducible cytokine A17; TARC; thymus and activation-regulated chemokine
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,001,463 - 59,014,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,001,464 - 59,005,230 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,630,918 - 55,633,430 (-)NCBI
ROS_Cfam_1.0259,539,866 - 59,550,154 (-)NCBI
ROS_Cfam_1.0 Ensembl259,539,866 - 59,551,785 (-)Ensembl
UMICH_Zoey_3.1256,371,394 - 56,373,906 (-)NCBI
UNSW_CanFamBas_1.0257,379,129 - 57,381,635 (-)NCBI
UU_Cfam_GSD_1.0258,272,358 - 58,274,870 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
cannabidiol  (EXP)
luteolin  (EXP)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:11642275   PMID:20022349   PMID:20837364   PMID:20860556  


Genomics

Comparative Map Data
CCL17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,001,463 - 59,014,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,001,464 - 59,005,230 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha255,630,918 - 55,633,430 (-)NCBI
ROS_Cfam_1.0259,539,866 - 59,550,154 (-)NCBI
ROS_Cfam_1.0 Ensembl259,539,866 - 59,551,785 (-)Ensembl
UMICH_Zoey_3.1256,371,394 - 56,373,906 (-)NCBI
UNSW_CanFamBas_1.0257,379,129 - 57,381,635 (-)NCBI
UU_Cfam_GSD_1.0258,272,358 - 58,274,870 (-)NCBI
CCL17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381657,396,093 - 57,416,063 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1657,404,767 - 57,416,063 (+)EnsemblGRCh38hg38GRCh38
GRCh371657,438,679 - 57,449,975 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,996,180 - 56,007,475 (+)NCBINCBI36hg18NCBI36
Build 341655,996,179 - 56,007,475NCBI
Celera1641,938,673 - 41,949,969 (+)NCBI
Cytogenetic Map16q21NCBI
HuRef1643,306,559 - 43,317,854 (+)NCBIHuRef
CHM1_11658,846,760 - 58,858,057 (+)NCBICHM1_1
T2T-CHM13v2.01663,199,942 - 63,211,239 (+)NCBI
Ccl17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39895,535,996 - 95,538,666 (+)NCBIGRCm39mm39
GRCm39 Ensembl895,537,081 - 95,538,664 (+)Ensembl
GRCm38894,809,380 - 94,812,038 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,810,453 - 94,812,036 (+)EnsemblGRCm38mm10GRCm38
MGSCv37897,334,353 - 97,335,936 (+)NCBIGRCm37mm9NCBIm37
MGSCv36897,699,598 - 97,701,165 (+)NCBImm8
Celera899,134,583 - 99,136,166 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.85NCBI
Ccl17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21910,202,317 - 10,203,768 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1910,202,128 - 10,203,819 (-)Ensembl
Rnor_6.01910,619,220 - 10,620,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1910,619,220 - 10,620,671 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01910,614,027 - 10,615,478 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41910,641,376 - 10,642,827 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11910,646,201 - 10,647,653 (-)NCBI
Celera1910,088,700 - 10,090,151 (-)NCBICelera
Cytogenetic Map19p13NCBI
Ccl17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543315,053,061 - 15,054,572 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543315,052,616 - 15,054,732 (+)NCBIChiLan1.0ChiLan1.0
CCL17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11656,810,923 - 56,822,131 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1656,819,949 - 56,822,131 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01637,678,518 - 37,689,350 (+)NCBIMhudiblu_PPA_v0panPan3
Ccl17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,112,663 - 50,114,927 (-)NCBI
SpeTri2.0NW_0049364759,475,013 - 9,476,326 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCL17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl619,345,941 - 19,348,926 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1619,345,929 - 19,372,972 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2617,342,591 - 17,345,444 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCL17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1543,343,525 - 43,350,096 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl543,346,329 - 43,348,599 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604732,869,286 - 32,872,957 (-)NCBIVero_WHO_p1.0
Ccl17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474628,655,801 - 28,657,470 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474628,655,288 - 28,657,563 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 6 4
Below cutoff 5 3 15 2 6 2 5 2 5 3 5 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000013912   ⟹   ENSCAFP00000012872
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl259,001,464 - 59,005,230 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000078736   ⟹   ENSCAFP00000048446
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl259,001,464 - 59,002,829 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000089341   ⟹   ENSCAFP00000047173
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl259,001,464 - 59,004,126 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845005907   ⟹   ENSCAFP00845004697
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl259,539,866 - 59,542,528 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845005917   ⟹   ENSCAFP00845004706
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl259,539,866 - 59,541,231 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845005928   ⟹   ENSCAFP00845004715
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl259,539,874 - 59,551,785 (-)Ensembl
RefSeq Acc Id: NM_001003051   ⟹   NP_001003051
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1259,001,464 - 59,003,976 (-)NCBI
Dog10K_Boxer_Tasha255,630,918 - 55,633,430 (-)NCBI
ROS_Cfam_1.0259,539,866 - 59,542,378 (-)NCBI
UMICH_Zoey_3.1256,371,394 - 56,373,906 (-)NCBI
UNSW_CanFamBas_1.0257,379,129 - 57,381,635 (-)NCBI
UU_Cfam_GSD_1.0258,272,358 - 58,274,870 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038657714   ⟹   XP_038513642
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0259,539,870 - 59,550,154 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001003051 (Get FASTA)   NCBI Sequence Viewer  
  XP_038513642 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB62131 (Get FASTA)   NCBI Sequence Viewer  
  Q95N01 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003051   ⟸   NM_001003051
- Peptide Label: precursor
- UniProtKB: Q95N01 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSCAFP00000048446   ⟸   ENSCAFT00000078736
RefSeq Acc Id: ENSCAFP00000012872   ⟸   ENSCAFT00000013912
RefSeq Acc Id: ENSCAFP00000047173   ⟸   ENSCAFT00000089341
RefSeq Acc Id: XP_038513642   ⟸   XM_038657714
- Peptide Label: isoform X1
- UniProtKB: Q95N01 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSCAFP00845004697   ⟸   ENSCAFT00845005907
RefSeq Acc Id: ENSCAFP00845004715   ⟸   ENSCAFT00845005928
RefSeq Acc Id: ENSCAFP00845004706   ⟸   ENSCAFT00845005917
Protein Domains
SCY


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008754 Ensembl
  ENSCAFG00030002926 UniProtKB/Swiss-Prot
  ENSCAFG00040011362 UniProtKB/Swiss-Prot
  ENSCAFG00845003329 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00030004835 UniProtKB/Swiss-Prot
  ENSCAFP00040018236 UniProtKB/Swiss-Prot
  ENSCAFP00845004697.1 UniProtKB/TrEMBL
  ENSCAFP00845004706.1 UniProtKB/TrEMBL
  ENSCAFP00845004715 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00030005436 UniProtKB/Swiss-Prot
  ENSCAFT00040021004 UniProtKB/Swiss-Prot
  ENSCAFT00845005907.1 UniProtKB/TrEMBL
  ENSCAFT00845005917.1 UniProtKB/TrEMBL
  ENSCAFT00845005928 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403586 UniProtKB/Swiss-Prot
NCBI Gene CCL17 ENTREZGENE
PANTHER PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SMALL_CYTOKINES_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I3MLL3_CANLF UniProtKB/TrEMBL
  A0A8I3MV39_CANLF UniProtKB/TrEMBL
  CCL17_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:38882 ENTREZGENE