ECM1 (extracellular matrix protein 1) - Rat Genome Database

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Gene: ECM1 (extracellular matrix protein 1) Canis lupus familiaris
Analyze
Symbol: ECM1
Name: extracellular matrix protein 1
RGD ID: 12364310
Description: ENCODES a protein that exhibits interleukin-2 receptor binding (inferred); protease binding (inferred); INVOLVED IN chondrocyte development (ortholog); endochondral bone growth (ortholog); inflammatory response (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); hepatocellular carcinoma (ortholog); FOUND IN collagen-containing extracellular matrix (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,696,125 - 59,701,990 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,696,477 - 59,701,744 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,142,307 - 59,148,147 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,711,672 - 60,717,511 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,697,493 - 60,717,511 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,542,109 - 59,547,950 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,625,886 - 59,631,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,353,552 - 60,359,392 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ECM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,696,125 - 59,701,990 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,696,477 - 59,701,744 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1759,142,307 - 59,148,147 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,711,672 - 60,717,511 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,697,493 - 60,717,511 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,542,109 - 59,547,950 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,625,886 - 59,631,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,353,552 - 60,359,392 (+)NCBIUU_Cfam_GSD_1.0
ECM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,508,109 - 150,513,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1150,508,062 - 150,513,789 (+)EnsemblGRCh38hg38GRCh38
GRCh371150,480,585 - 150,486,265 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,747,207 - 148,752,660 (+)NCBINCBI36Build 36hg18NCBI36
Celera1123,596,250 - 123,602,028 (+)NCBICelera
Cytogenetic Map1q21.2NCBI
HuRef1121,858,654 - 121,864,432 (+)NCBIHuRef
CHM1_11151,876,297 - 151,882,073 (+)NCBICHM1_1
T2T-CHM13v2.01149,632,949 - 149,638,627 (+)NCBIT2T-CHM13v2.0
Ecm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,641,459 - 95,646,880 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,641,459 - 95,646,881 (-)EnsemblGRCm39 Ensembl
GRCm38395,734,147 - 95,739,876 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,734,147 - 95,739,569 (-)EnsemblGRCm38mm10GRCm38
MGSCv37395,538,071 - 95,543,492 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,819,554 - 95,824,967 (-)NCBIMGSCv36mm8
Celera397,167,107 - 97,172,528 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.91NCBI
Ecm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82185,976,439 - 185,981,656 (-)NCBIGRCr8
mRatBN7.22183,287,491 - 183,292,729 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2183,287,322 - 183,292,671 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2190,952,324 - 190,957,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,747,934 - 188,753,625 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,584,856 - 183,590,023 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02197,855,468 - 197,860,973 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2197,855,460 - 197,860,699 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02217,345,268 - 217,350,509 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,525,156 - 190,530,323 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12190,489,759 - 190,489,956 (-)NCBI
Celera2175,817,503 - 175,822,670 (-)NCBICelera
Cytogenetic Map2q34NCBI
Ecm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955413290,363 - 299,130 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955413293,295 - 299,293 (-)NCBIChiLan1.0ChiLan1.0
ECM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,324,741 - 99,330,326 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,069,972 - 99,084,160 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,853,337 - 125,858,904 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11129,502,041 - 129,507,819 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1129,502,041 - 129,507,819 (+)Ensemblpanpan1.1panPan2
Ecm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,720,545 - 21,726,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936580750,736 - 756,771 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936580750,423 - 756,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,615,778 - 98,621,836 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,615,776 - 98,633,081 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24107,904,906 - 107,909,543 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603812,777,257 - 12,783,212 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ecm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,233,727 - 18,240,601 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,234,537 - 18,239,896 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ECM1
59 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 2 6 3 6 6 10 6
Low 1 3 16 6 3 6 6 6
Below cutoff 8

Sequence


RefSeq Acc Id: ENSCAFT00000019091   ⟹   ENSCAFP00000017697
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1759,696,477 - 59,701,744 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000092186   ⟹   ENSCAFP00000050127
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1759,696,477 - 59,701,744 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032050   ⟹   ENSCAFP00845025059
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1760,697,493 - 60,717,265 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032213   ⟹   ENSCAFP00845025182
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1760,711,968 - 60,717,511 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032275   ⟹   ENSCAFP00845025230
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1760,711,968 - 60,717,511 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845032349   ⟹   ENSCAFP00845025288
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1760,711,970 - 60,717,350 (+)Ensembl
RefSeq Acc Id: XM_038423067   ⟹   XP_038278995
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01760,711,672 - 60,717,511 (+)NCBI
RefSeq Acc Id: XM_038499564   ⟹   XP_038355492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11759,542,109 - 59,547,950 (+)NCBI
RefSeq Acc Id: XM_038562134   ⟹   XP_038418062
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01760,353,552 - 60,359,392 (+)NCBI
RefSeq Acc Id: XM_038626231   ⟹   XP_038482159
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01759,625,886 - 59,631,725 (+)NCBI
RefSeq Acc Id: XM_845921   ⟹   XP_851014
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11759,696,125 - 59,701,990 (+)NCBI
Dog10K_Boxer_Tasha1759,142,307 - 59,148,147 (+)NCBI
Sequence:
RefSeq Acc Id: XP_851014   ⟸   XM_845921
- UniProtKB: A0A8P0NZY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000017697   ⟸   ENSCAFT00000019091
RefSeq Acc Id: ENSCAFP00000050127   ⟸   ENSCAFT00000092186
RefSeq Acc Id: XP_038355492   ⟸   XM_038499564
RefSeq Acc Id: XP_038482159   ⟸   XM_038626231
RefSeq Acc Id: XP_038278995   ⟸   XM_038423067
- UniProtKB: A0A8P0NZY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038418062   ⟸   XM_038562134
- UniProtKB: A0A8P0NZY6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845025059   ⟸   ENSCAFT00845032050
RefSeq Acc Id: ENSCAFP00845025182   ⟸   ENSCAFT00845032213
RefSeq Acc Id: ENSCAFP00845025230   ⟸   ENSCAFT00845032275
RefSeq Acc Id: ENSCAFP00845025288   ⟸   ENSCAFT00845032349


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012022 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00845018089 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019016.5 UniProtKB/TrEMBL
  ENSCAFT00000019091.5 UniProtKB/TrEMBL
  ENSCAFT00000082505.2 UniProtKB/TrEMBL
  ENSCAFT00000092186.2 UniProtKB/TrEMBL
  ENSCAFT00845032050.1 UniProtKB/TrEMBL
  ENSCAFT00845032213.1 UniProtKB/TrEMBL
  ENSCAFT00845032275.1 UniProtKB/TrEMBL
  ENSCAFT00845032349 ENTREZGENE
  ENSCAFT00845032349.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.10 UniProtKB/TrEMBL
InterPro ECM1 UniProtKB/TrEMBL
  Serum_albumin-like UniProtKB/TrEMBL
NCBI Gene ECM1 ENTREZGENE
PANTHER EXTRACELLULAR MATRIX PROTEIN 1 UniProtKB/TrEMBL
  PTHR16776 UniProtKB/TrEMBL
Pfam ECM1 UniProtKB/TrEMBL
Superfamily-SCOP SSF48552 UniProtKB/TrEMBL
UniProt A0A8I3P2D9_CANLF UniProtKB/TrEMBL
  A0A8I3P5P0_CANLF UniProtKB/TrEMBL
  A0A8I3P5S8_CANLF UniProtKB/TrEMBL
  A0A8I3P695_CANLF UniProtKB/TrEMBL
  A0A8P0NDR8_CANLF UniProtKB/TrEMBL
  A0A8P0NZY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SGU8_CANLF UniProtKB/TrEMBL
  A0A8P0T2U7_CANLF UniProtKB/TrEMBL