IL10RA (interleukin 10 receptor subunit alpha) - Rat Genome Database

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Gene: IL10RA (interleukin 10 receptor subunit alpha) Canis lupus familiaris
Analyze
Symbol: IL10RA
Name: interleukin 10 receptor subunit alpha
RGD ID: 12381536
Description: ENCODES a protein that exhibits interleukin-10 binding (ortholog); interleukin-10 receptor activity (ortholog); INVOLVED IN interleukin-10-mediated signaling pathway (ortholog); regulation of synapse organization (ortholog); response to lipopolysaccharide (ortholog); PARTICIPATES IN Interleukin-10 signaling pathway; ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); COVID-19 (ortholog); FOUND IN apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-10 receptor subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,675,775 - 15,688,935 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,677,547 - 15,682,163 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,725,841 - 15,738,336 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,617,611 - 15,630,201 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,617,622 - 15,630,212 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,755,417 - 15,767,913 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,658,874 - 15,671,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,700,417 - 15,712,914 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
IL10RA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,675,775 - 15,688,935 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,677,547 - 15,682,163 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,725,841 - 15,738,336 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,617,611 - 15,630,201 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,617,622 - 15,630,212 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,755,417 - 15,767,913 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,658,874 - 15,671,434 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,700,417 - 15,712,914 (-)NCBIUU_Cfam_GSD_1.0
IL10RA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811117,986,394 - 118,003,037 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11117,986,370 - 118,003,037 (+)EnsemblGRCh38hg38GRCh38
GRCh3711117,857,109 - 117,873,752 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,362,319 - 117,377,404 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411117,362,318 - 117,377,404NCBI
Celera11115,014,946 - 115,030,037 (+)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11113,790,784 - 113,805,875 (+)NCBIHuRef
CHM1_111117,742,666 - 117,757,757 (+)NCBICHM1_1
T2T-CHM13v2.011118,002,773 - 118,019,416 (+)NCBIT2T-CHM13v2.0
Il10ra
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39945,165,135 - 45,180,447 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl945,165,135 - 45,180,447 (-)EnsemblGRCm39 Ensembl
GRCm38945,253,837 - 45,269,149 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl945,253,837 - 45,269,149 (-)EnsemblGRCm38mm10GRCm38
MGSCv37945,061,922 - 45,077,229 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36945,004,833 - 45,020,128 (-)NCBIMGSCv36mm8
Celera942,530,039 - 42,545,574 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Il10ra
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,459,754 - 54,474,786 (-)NCBIGRCr8
mRatBN7.2845,563,009 - 45,578,041 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,563,137 - 45,578,061 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx851,059,536 - 51,072,968 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,338,295 - 49,351,727 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0847,208,844 - 47,222,279 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,558,062 - 49,573,891 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,560,035 - 49,573,742 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0848,184,634 - 48,200,343 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4848,211,040 - 48,224,439 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1848,219,805 - 48,233,205 (-)NCBI
Celera845,147,695 - 45,161,094 (-)NCBICelera
Cytogenetic Map8q22NCBI
Il10ra
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,182,029 - 19,193,971 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541219,182,536 - 19,197,083 (+)NCBIChiLan1.0ChiLan1.0
IL10RA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29118,686,901 - 118,702,056 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111119,791,876 - 119,807,051 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011112,820,445 - 112,835,603 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111116,752,619 - 116,767,771 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11116,752,619 - 116,767,771 (+)Ensemblpanpan1.1panPan2
Il10ra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947100,178,025 - 100,191,000 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365423,099,430 - 3,113,210 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365423,099,484 - 3,113,159 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL10RA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl945,310,534 - 45,325,168 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1945,310,527 - 45,324,557 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,364,900 - 50,378,929 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL10RA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,357,081 - 109,372,557 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,357,133 - 109,372,697 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,683,781 - 16,699,148 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il10ra
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478413,386,965 - 13,403,014 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478413,386,793 - 13,399,871 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL10RA
162 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 5 1
Low 5 1 22 6 6 6 12 5 5
Below cutoff 4 6 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000020372   ⟹   ENSCAFP00000018903
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl515,677,547 - 15,682,163 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845005620   ⟹   ENSCAFP00845004460
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl515,617,622 - 15,630,212 (-)Ensembl
RefSeq Acc Id: XM_038474883   ⟹   XP_038330811
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1515,755,417 - 15,767,913 (-)NCBI
RefSeq Acc Id: XM_038509143   ⟹   XP_038365071
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha515,725,841 - 15,738,336 (-)NCBI
RefSeq Acc Id: XM_038536009   ⟹   XP_038391937
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0515,700,417 - 15,712,914 (-)NCBI
RefSeq Acc Id: XM_038600212   ⟹   XP_038456140
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0515,658,874 - 15,671,434 (-)NCBI
RefSeq Acc Id: XM_038664749   ⟹   XP_038520677
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0515,617,611 - 15,630,201 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000018903   ⟸   ENSCAFT00000020372
RefSeq Acc Id: XP_038330811   ⟸   XM_038474883
RefSeq Acc Id: XP_038456140   ⟸   XM_038600212
RefSeq Acc Id: XP_038520677   ⟸   XM_038664749
- UniProtKB: A0A8C0JJI0 (UniProtKB/TrEMBL),   A0A8C0MVW9 (UniProtKB/TrEMBL),   A0A8I3MNN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038365071   ⟸   XM_038509143
- UniProtKB: A0A8C0RVM6 (UniProtKB/TrEMBL),   A0A8P0SHP2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038391937   ⟸   XM_038536009
- UniProtKB: A0A8C0JJI0 (UniProtKB/TrEMBL),   A0A8C0MVW9 (UniProtKB/TrEMBL),   A0A8I3MNN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845004460   ⟸   ENSCAFT00845005620
Protein Domains
Fibronectin type-III   Interferon/interleukin receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012844 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030009697 UniProtKB/TrEMBL
  ENSCAFG00040001585 UniProtKB/TrEMBL
  ENSCAFG00845003194 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000020372.5 UniProtKB/TrEMBL
  ENSCAFT00030017931.1 UniProtKB/TrEMBL
  ENSCAFT00030017975.1 UniProtKB/TrEMBL
  ENSCAFT00040003024.1 UniProtKB/TrEMBL
  ENSCAFT00040003044.1 UniProtKB/TrEMBL
  ENSCAFT00845005620 ENTREZGENE
  ENSCAFT00845005620.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Interferon/interleukin_rcp_dom UniProtKB/TrEMBL
NCBI Gene IL10RA ENTREZGENE
PANTHER INTERFERON/INTERLEUKIN RECEPTOR UniProtKB/TrEMBL
  INTERLEUKIN-10 RECEPTOR SUBUNIT ALPHA UniProtKB/TrEMBL
Pfam Interfer-bind UniProtKB/TrEMBL
  Tissue_fac UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A8C0JJI0 ENTREZGENE
  A0A8C0MVW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PQP5_CANLF UniProtKB/TrEMBL
  A0A8C0RGN0_CANLF UniProtKB/TrEMBL
  A0A8C0RVM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MNN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SHP2 ENTREZGENE
UniProt Secondary A0A8P0SHP2 UniProtKB/TrEMBL
VGNC ID VGNC:41929 ENTREZGENE