APPL2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: APPL2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2) Canis lupus familiaris
Analyze
Symbol: APPL2
Name: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
RGD ID: 12223836
Description: ENCODES a protein that exhibits identical protein binding (inferred); phosphatidylinositol binding (inferred); phosphatidylserine binding (inferred); INVOLVED IN adiponectin-activated signaling pathway (inferred); cellular response to hepatocyte growth factor stimulus (inferred); cold acclimation (inferred); ASSOCIATED WITH genetic disease (ortholog); Prostatic Neoplasms (ortholog); substance-related disorder (ortholog); FOUND IN cell projection (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: amyloid beta (A4) precursor-like protein 2; DCC-interacting protein 13-beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,192,261 - 33,243,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1033,191,602 - 33,242,669 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1033,111,933 - 33,162,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01034,033,756 - 34,084,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1034,033,772 - 34,084,225 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11033,769,093 - 33,819,698 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01034,053,225 - 34,103,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01034,246,325 - 34,297,170 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
APPL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11033,192,261 - 33,243,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1033,191,602 - 33,242,669 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1033,111,933 - 33,162,406 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01034,033,756 - 34,084,221 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1034,033,772 - 34,084,225 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11033,769,093 - 33,819,698 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01034,053,225 - 34,103,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01034,246,325 - 34,297,170 (+)NCBIUU_Cfam_GSD_1.0
APPL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812105,173,300 - 105,236,174 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12105,173,297 - 105,236,203 (-)EnsemblGRCh38hg38GRCh38
GRCh3712105,567,078 - 105,629,952 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612104,091,205 - 104,154,138 (-)NCBINCBI36Build 36hg18NCBI36
Celera12105,231,366 - 105,294,273 (-)NCBICelera
Cytogenetic Map12q23.3NCBI
HuRef12102,626,453 - 102,689,404 (-)NCBIHuRef
CHM1_112105,532,775 - 105,595,738 (-)NCBICHM1_1
T2T-CHM13v2.012105,135,121 - 105,197,990 (-)NCBIT2T-CHM13v2.0
Appl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391083,435,897 - 83,484,741 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1083,435,897 - 83,484,602 (-)EnsemblGRCm39 Ensembl
GRCm381083,600,033 - 83,648,877 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1083,600,033 - 83,648,738 (-)EnsemblGRCm38mm10GRCm38
MGSCv371083,062,778 - 83,111,409 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361083,029,832 - 83,078,463 (-)NCBIMGSCv36mm8
Celera1085,587,519 - 85,636,067 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.29NCBI
Appl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8722,019,480 - 22,072,386 (+)NCBIGRCr8
mRatBN7.2720,135,248 - 20,184,757 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl720,135,375 - 20,184,754 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx722,105,205 - 22,156,954 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0724,267,960 - 24,319,709 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0724,044,969 - 24,096,718 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0726,256,179 - 26,306,128 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl726,256,459 - 26,306,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0726,387,115 - 26,436,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4722,279,273 - 22,328,427 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera717,339,053 - 17,386,872 (+)NCBICelera
Cytogenetic Map7q13NCBI
Appl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540539,503,020 - 39,540,335 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540539,503,020 - 39,540,069 (-)NCBIChiLan1.0ChiLan1.0
APPL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210113,243,186 - 113,306,443 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112113,239,582 - 113,302,821 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012102,755,388 - 102,818,686 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112106,150,955 - 106,214,038 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12106,151,969 - 106,206,879 (-)Ensemblpanpan1.1panPan2
Appl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494516,467,066 - 16,530,048 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364929,477,373 - 9,526,692 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364929,477,483 - 9,526,692 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APPL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl579,356,067 - 79,412,235 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1579,356,046 - 79,412,235 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2582,650,763 - 82,706,934 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q2.3NCBI
APPL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111100,400,093 - 100,469,234 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11100,400,084 - 100,462,507 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037144,551,093 - 144,614,465 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Appl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247503,789,022 - 3,827,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247503,789,015 - 3,827,079 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in APPL2
506 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 19 5 6 5 6 12 8 10 6
Low 3 1 1 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005625955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005625956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022424522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022424523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038488844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038550808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_538418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000002989   ⟹   ENSCAFP00000002772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1033,199,006 - 33,242,290 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000069988   ⟹   ENSCAFP00000059188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1033,191,602 - 33,242,669 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000076358   ⟹   ENSCAFP00000051353
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1033,195,004 - 33,242,290 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000080274   ⟹   ENSCAFP00000061729
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1033,191,602 - 33,242,290 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845010496   ⟹   ENSCAFP00845008162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1034,033,772 - 34,084,225 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845010511   ⟹   ENSCAFP00845008174
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1034,033,772 - 34,084,225 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845010548   ⟹   ENSCAFP00845008209
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1034,033,875 - 34,084,204 (+)Ensembl
RefSeq Acc Id: XM_005625955   ⟹   XP_005626012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11033,192,264 - 33,243,034 (+)NCBI
Dog10K_Boxer_Tasha1033,111,935 - 33,162,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022424522   ⟹   XP_022280230
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11033,192,263 - 33,243,034 (+)NCBI
Dog10K_Boxer_Tasha1033,111,935 - 33,162,406 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022424523   ⟹   XP_022280231
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11033,192,261 - 33,235,070 (+)NCBI
Dog10K_Boxer_Tasha1033,111,933 - 33,154,661 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038488841   ⟹   XP_038344769
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11033,769,095 - 33,819,698 (+)NCBI
RefSeq Acc Id: XM_038488842   ⟹   XP_038344770
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11033,769,095 - 33,819,698 (+)NCBI
RefSeq Acc Id: XM_038488843   ⟹   XP_038344771
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11033,769,095 - 33,819,698 (+)NCBI
RefSeq Acc Id: XM_038488844   ⟹   XP_038344772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11033,769,093 - 33,811,952 (+)NCBI
RefSeq Acc Id: XM_038550805   ⟹   XP_038406733
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01034,246,327 - 34,297,170 (+)NCBI
RefSeq Acc Id: XM_038550806   ⟹   XP_038406734
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01034,246,327 - 34,297,170 (+)NCBI
RefSeq Acc Id: XM_038550807   ⟹   XP_038406735
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01034,246,327 - 34,297,170 (+)NCBI
RefSeq Acc Id: XM_038550808   ⟹   XP_038406736
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01034,246,325 - 34,289,185 (+)NCBI
RefSeq Acc Id: XM_038614725   ⟹   XP_038470653
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01034,053,227 - 34,103,854 (+)NCBI
RefSeq Acc Id: XM_038614726   ⟹   XP_038470654
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01034,053,227 - 34,103,854 (+)NCBI
RefSeq Acc Id: XM_038614727   ⟹   XP_038470655
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01034,053,227 - 34,103,854 (+)NCBI
RefSeq Acc Id: XM_038614728   ⟹   XP_038470656
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01034,053,225 - 34,096,108 (+)NCBI
RefSeq Acc Id: XM_038680093   ⟹   XP_038536021
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01034,033,758 - 34,084,221 (+)NCBI
RefSeq Acc Id: XM_038680094   ⟹   XP_038536022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01034,033,758 - 34,084,221 (+)NCBI
RefSeq Acc Id: XM_038680095   ⟹   XP_038536023
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01034,033,758 - 34,084,221 (+)NCBI
RefSeq Acc Id: XM_038680096   ⟹   XP_038536024
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01034,033,756 - 34,076,475 (+)NCBI
RefSeq Acc Id: XM_538418   ⟹   XP_538418
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11033,192,264 - 33,243,034 (+)NCBI
Dog10K_Boxer_Tasha1033,111,935 - 33,162,406 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_538418   ⟸   XM_538418
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JVY4 (UniProtKB/TrEMBL),   A0A8I3MVM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005626012   ⟸   XM_005625955
- Peptide Label: isoform X2
- UniProtKB: A0A8I3MVM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022280231   ⟸   XM_022424523
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_022280230   ⟸   XM_022424522
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MVM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000059188   ⟸   ENSCAFT00000069988
RefSeq Acc Id: ENSCAFP00000061729   ⟸   ENSCAFT00000080274
RefSeq Acc Id: ENSCAFP00000051353   ⟸   ENSCAFT00000076358
RefSeq Acc Id: ENSCAFP00000002772   ⟸   ENSCAFT00000002989
RefSeq Acc Id: XP_038344772   ⟸   XM_038488844
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038344769   ⟸   XM_038488841
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038344770   ⟸   XM_038488842
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038344771   ⟸   XM_038488843
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038470656   ⟸   XM_038614728
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038470653   ⟸   XM_038614725
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038470654   ⟸   XM_038614726
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038470655   ⟸   XM_038614727
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038536024   ⟸   XM_038680096
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038536021   ⟸   XM_038680093
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JVY4 (UniProtKB/TrEMBL),   A0A8I3MVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536022   ⟸   XM_038680094
- Peptide Label: isoform X2
- UniProtKB: A0A8I3MVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536023   ⟸   XM_038680095
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406736   ⟸   XM_038550808
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038406733   ⟸   XM_038550805
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JVY4 (UniProtKB/TrEMBL),   A0A8I3MVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406734   ⟸   XM_038550806
- Peptide Label: isoform X2
- UniProtKB: A0A8I3MVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038406735   ⟸   XM_038550807
- Peptide Label: isoform X3
- UniProtKB: A0A8I3MVM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845008209   ⟸   ENSCAFT00845010548
RefSeq Acc Id: ENSCAFP00845008174   ⟸   ENSCAFT00845010511
RefSeq Acc Id: ENSCAFP00845008162   ⟸   ENSCAFT00845010496
Protein Domains
BAR   PH   PID

Promoters
RGD ID:13685005
Promoter ID:EPDNEW_C3073
Type:initiation region
Name:APPL2_1
Description:adaptor protein, phosphotyrosine interacting with PH domain andleucine zipper 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11033,192,324 - 33,192,384EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001885 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040008313 UniProtKB/TrEMBL
  ENSCAFG00845005921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002989.5 UniProtKB/TrEMBL
  ENSCAFT00000069988.2 UniProtKB/TrEMBL
  ENSCAFT00000076358.2 UniProtKB/TrEMBL
  ENSCAFT00000080274.2 UniProtKB/TrEMBL
  ENSCAFT00040015872.1 UniProtKB/TrEMBL
  ENSCAFT00040016240.1 UniProtKB/TrEMBL
  ENSCAFT00845010496 ENTREZGENE
  ENSCAFT00845010496.1 UniProtKB/TrEMBL
  ENSCAFT00845010511.1 UniProtKB/TrEMBL
  ENSCAFT00845010548.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/TrEMBL
  BAR_APPL2 UniProtKB/TrEMBL
  BAR_dom UniProtKB/TrEMBL
  DP13A/B UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PH_DP13A/B UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
  PTB_APPL UniProtKB/TrEMBL
NCBI Gene APPL2 ENTREZGENE
PANTHER ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 UniProtKB/TrEMBL
  DCC-INTERACTING PROTEIN 13-BETA UniProtKB/TrEMBL
Pfam BAR_3 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PID UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF103657 UniProtKB/TrEMBL
UniProt A0A8C0JVY4 ENTREZGENE
  A0A8C0QQ52_CANLF UniProtKB/TrEMBL
  A0A8C0S0U6_CANLF UniProtKB/TrEMBL
  A0A8I3MVM2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MVN3_CANLF UniProtKB/TrEMBL
  A0A8I3MYD2_CANLF UniProtKB/TrEMBL
  A0A8P0N504_CANLF UniProtKB/TrEMBL
  A0A8P0T404_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0P8D3 UniProtKB/TrEMBL
  A0A8P0TDH3 UniProtKB/TrEMBL
VGNC ID VGNC:38013 ENTREZGENE