PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) - Rat Genome Database

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Gene: PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) Canis lupus familiaris
Analyze
Symbol: PIK3R1
Name: phosphoinositide-3-kinase regulatory subunit 1
RGD ID: 12122424
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (ortholog); 1-phosphatidylinositol-3-kinase regulator activity (ortholog); ATPase binding (ortholog); INVOLVED IN B cell differentiation (ortholog); cellular response to fatty acid (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH agammaglobulinemia 7 (ortholog); Alzheimer's disease (ortholog); Animal Mammary Neoplasms (ortholog); FOUND IN phosphatidylinositol 3-kinase complex (ortholog); phosphatidylinositol 3-kinase complex, class IA (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 3-kinase regulatory subunit alpha; phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1253,447,802 - 53,527,563 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl253,448,286 - 53,524,970 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha250,408,936 - 50,489,628 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0253,951,256 - 54,032,010 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl253,960,673 - 54,031,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1251,011,708 - 51,092,420 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0251,791,194 - 51,871,863 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0252,678,736 - 52,759,442 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
B cell differentiation  (IEA,ISO)
cellular response to fatty acid  (ISO)
cellular response to insulin stimulus  (IEA,ISO)
cellular response to UV  (IEA,ISO)
cytokine-mediated signaling pathway  (IEA)
extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
glucose metabolic process  (ISO)
growth hormone receptor signaling pathway  (IEA)
insulin receptor signaling pathway  (IEA,ISO)
insulin-like growth factor receptor signaling pathway  (IEA,ISO)
interleukin-18-mediated signaling pathway  (IEA)
intracellular glucose homeostasis  (IEA)
intrinsic apoptotic signaling pathway in response to DNA damage  (IEA,ISO)
myeloid leukocyte migration  (IEA,ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of blood pressure  (ISO)
negative regulation of cell adhesion  (IEA,ISO)
negative regulation of cell-cell adhesion  (ISO)
negative regulation of cell-matrix adhesion  (IEA,ISO)
negative regulation of heart rate  (ISO)
negative regulation of muscle cell apoptotic process  (ISO)
negative regulation of osteoclast differentiation  (IEA,ISO)
negative regulation of proteolysis  (ISO)
negative regulation of smooth muscle cell proliferation  (ISO)
negative regulation of stress fiber assembly  (IEA)
osteoclast differentiation  (IEA,ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IEA)
phosphatidylinositol metabolic process  (ISO)
phosphatidylinositol phosphate biosynthetic process  (IEA)
positive regulation of cell migration  (ISO)
positive regulation of endoplasmic reticulum unfolded protein response  (IEA)
positive regulation of filopodium assembly  (IEA)
positive regulation of focal adhesion disassembly  (IEA)
positive regulation of gene expression  (ISO)
positive regulation of lamellipodium assembly  (IEA)
positive regulation of leukocyte migration  (IEA,ISO)
positive regulation of myoblast differentiation  (ISO)
positive regulation of protein import into nucleus  (IEA)
positive regulation of protein phosphorylation  (ISO)
positive regulation of RNA splicing  (IEA)
positive regulation of smooth muscle cell proliferation  (IEA)
positive regulation of synapse assembly  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of tumor necrosis factor production  (IEA,ISO)
protein import into nucleus  (IEA,ISO)
protein stabilization  (IEA)
regulation of protein localization to plasma membrane  (IEA,ISO)
regulation of stress fiber assembly  (IEA,ISO)
regulation of toll-like receptor 4 signaling pathway  (IEA)
response to amino acid  (ISO)
response to cAMP  (ISO)
response to dexamethasone  (ISO)
response to endoplasmic reticulum stress  (IEA)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to fatty acid  (ISO)
response to fructose  (ISO)
response to glucocorticoid  (ISO)
response to growth factor  (ISO)
response to insulin  (ISO)
response to iron(II) ion  (ISO)
response to nutrient  (ISO)
response to progesterone  (ISO)
response to testosterone  (ISO)
response to xenobiotic stimulus  (ISO)
response to yeast  (ISO)
signal transduction  (IEA)
transcription by RNA polymerase II  (IEA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:17535735   PMID:19043794   PMID:22301074   PMID:30032202   PMID:31570656  


Genomics

Comparative Map Data
PIK3R1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1253,447,802 - 53,527,563 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl253,448,286 - 53,524,970 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha250,408,936 - 50,489,628 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0253,951,256 - 54,032,010 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl253,960,673 - 54,031,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1251,011,708 - 51,092,420 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0251,791,194 - 51,871,863 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0252,678,736 - 52,759,442 (+)NCBIUU_Cfam_GSD_1.0
PIK3R1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38568,215,756 - 68,301,821 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl568,215,740 - 68,301,821 (+)EnsemblGRCh38hg38GRCh38
GRCh37567,511,584 - 67,597,649 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36567,558,218 - 67,633,405 (+)NCBINCBI36Build 36hg18NCBI36
Build 34567,622,250 - 67,633,403NCBI
Celera564,520,829 - 64,597,175 (+)NCBICelera
Cytogenetic Map5q13.1NCBI
HuRef564,468,818 - 64,555,164 (+)NCBIHuRef
CHM1_1567,511,846 - 67,597,747 (+)NCBICHM1_1
T2T-CHM13v2.0569,037,928 - 69,124,117 (+)NCBIT2T-CHM13v2.0
Pik3r1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913101,817,269 - 101,904,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13101,817,071 - 101,904,725 (-)EnsemblGRCm39 Ensembl
GRCm3813101,680,761 - 101,768,217 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13101,680,563 - 101,768,217 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713102,450,716 - 102,538,172 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613102,781,018 - 102,792,904 (-)NCBIMGSCv36mm8
Celera13105,285,857 - 105,373,612 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1353.92NCBI
Pik3r1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8234,612,946 - 34,697,660 (-)NCBIGRCr8
mRatBN7.2232,878,942 - 32,963,668 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl232,882,032 - 32,963,631 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx240,014,126 - 40,099,015 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0238,073,343 - 38,158,218 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0232,921,198 - 33,006,089 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0231,742,326 - 31,826,882 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl231,745,088 - 31,826,867 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0250,891,225 - 50,965,217 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4232,602,673 - 32,675,350 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1232,523,041 - 32,595,719 (-)NCBI
Celera228,878,690 - 28,948,863 (-)NCBICelera
RH 3.4 Map2111.0RGD
Cytogenetic Map2q12NCBI
Pik3r1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554461,020,043 - 1,098,820 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554461,020,707 - 1,098,327 (-)NCBIChiLan1.0ChiLan1.0
PIK3R1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2445,620,454 - 45,705,861 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1543,777,000 - 43,859,488 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0545,701,219 - 45,786,652 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1547,268,477 - 47,350,960 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl547,267,286 - 47,350,960 (-)Ensemblpanpan1.1panPan2
Pik3r1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213192,252,011 - 192,336,736 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364801,188,183 - 1,273,537 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364801,188,408 - 1,273,210 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3R1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1646,511,521 - 46,523,609 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11646,434,757 - 46,523,626 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21650,135,837 - 50,148,434 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3R1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1464,321,296 - 64,406,188 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl464,321,078 - 64,406,519 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604913,008,003 - 13,093,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3r1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248151,289,997 - 1,369,610 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248151,290,106 - 1,376,961 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PIK3R1
892 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 4 14 6 6 6 6 6 9 10 6
Low 1 1 8 3 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003433815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014108822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014108824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022410134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038459839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038469959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038530768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038594991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038659066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_544363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB436616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000012216   ⟹   ENSCAFP00000011322
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl253,448,286 - 53,524,970 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000061673   ⟹   ENSCAFP00000054020
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl253,517,378 - 53,524,970 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000068054   ⟹   ENSCAFP00000045130
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl253,516,490 - 53,524,970 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000074878   ⟹   ENSCAFP00000061390
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl253,451,243 - 53,524,970 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000076972   ⟹   ENSCAFP00000043843
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl253,515,992 - 53,524,970 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845020842   ⟹   ENSCAFP00845016363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl253,960,673 - 54,031,993 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845020896   ⟹   ENSCAFP00845016412
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl254,020,408 - 54,031,993 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845020954   ⟹   ENSCAFP00845016464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl254,022,197 - 54,029,456 (+)Ensembl
RefSeq Acc Id: XM_003433815   ⟹   XP_003433863
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1253,515,897 - 53,527,563 (+)NCBI
Dog10K_Boxer_Tasha250,478,039 - 50,489,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014108822   ⟹   XP_013964297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1253,447,802 - 53,527,563 (+)NCBI
Dog10K_Boxer_Tasha250,409,846 - 50,489,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014108824   ⟹   XP_013964299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1253,447,802 - 53,527,563 (+)NCBI
Dog10K_Boxer_Tasha250,409,846 - 50,489,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022410134   ⟹   XP_022265842
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1253,451,286 - 53,527,563 (+)NCBI
Dog10K_Boxer_Tasha250,413,336 - 50,489,628 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038459835   ⟹   XP_038315763
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha250,408,936 - 50,489,628 (+)NCBI
RefSeq Acc Id: XM_038459839   ⟹   XP_038315767
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha250,409,047 - 50,489,628 (+)NCBI
RefSeq Acc Id: XM_038469953   ⟹   XP_038325881
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,011,708 - 51,092,420 (+)NCBI
RefSeq Acc Id: XM_038469954   ⟹   XP_038325882
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,012,618 - 51,092,420 (+)NCBI
RefSeq Acc Id: XM_038469955   ⟹   XP_038325883
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,011,819 - 51,092,420 (+)NCBI
RefSeq Acc Id: XM_038469956   ⟹   XP_038325884
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,016,107 - 51,092,420 (+)NCBI
RefSeq Acc Id: XM_038469957   ⟹   XP_038325885
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,012,618 - 51,092,420 (+)NCBI
RefSeq Acc Id: XM_038469958   ⟹   XP_038325886
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,082,587 - 51,088,571 (+)NCBI
RefSeq Acc Id: XM_038469959   ⟹   XP_038325887
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1251,080,801 - 51,092,420 (+)NCBI
RefSeq Acc Id: XM_038530761   ⟹   XP_038386689
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,678,736 - 52,759,442 (+)NCBI
RefSeq Acc Id: XM_038530763   ⟹   XP_038386691
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,679,646 - 52,759,442 (+)NCBI
RefSeq Acc Id: XM_038530764   ⟹   XP_038386692
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,678,847 - 52,759,442 (+)NCBI
RefSeq Acc Id: XM_038530765   ⟹   XP_038386693
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,683,136 - 52,759,442 (+)NCBI
RefSeq Acc Id: XM_038530766   ⟹   XP_038386694
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,679,646 - 52,759,442 (+)NCBI
RefSeq Acc Id: XM_038530767   ⟹   XP_038386695
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,749,642 - 52,755,626 (+)NCBI
RefSeq Acc Id: XM_038530768   ⟹   XP_038386696
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0252,747,854 - 52,759,442 (+)NCBI
RefSeq Acc Id: XM_038594986   ⟹   XP_038450914
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0251,791,194 - 51,871,863 (+)NCBI
RefSeq Acc Id: XM_038594987   ⟹   XP_038450915
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0251,792,104 - 51,871,863 (+)NCBI
RefSeq Acc Id: XM_038594988   ⟹   XP_038450916
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0251,791,305 - 51,871,863 (+)NCBI
RefSeq Acc Id: XM_038594989   ⟹   XP_038450917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0251,795,594 - 51,871,863 (+)NCBI
RefSeq Acc Id: XM_038594990   ⟹   XP_038450918
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0251,792,104 - 51,871,863 (+)NCBI
RefSeq Acc Id: XM_038594991   ⟹   XP_038450919
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0251,862,043 - 51,868,029 (+)NCBI
RefSeq Acc Id: XM_038659060   ⟹   XP_038514988
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0253,951,256 - 54,032,010 (+)NCBI
RefSeq Acc Id: XM_038659061   ⟹   XP_038514989
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0253,952,166 - 54,032,010 (+)NCBI
RefSeq Acc Id: XM_038659062   ⟹   XP_038514990
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0253,951,367 - 54,032,010 (+)NCBI
RefSeq Acc Id: XM_038659063   ⟹   XP_038514991
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0253,955,656 - 54,032,010 (+)NCBI
RefSeq Acc Id: XM_038659064   ⟹   XP_038514992
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0253,952,166 - 54,032,010 (+)NCBI
RefSeq Acc Id: XM_038659065   ⟹   XP_038514993
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0254,022,185 - 54,028,167 (+)NCBI
RefSeq Acc Id: XM_038659066   ⟹   XP_038514994
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0254,020,393 - 54,032,010 (+)NCBI
RefSeq Acc Id: XM_544363   ⟹   XP_544363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1253,517,759 - 53,523,748 (+)NCBI
Dog10K_Boxer_Tasha250,479,829 - 50,485,811 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003433863 (Get FASTA)   NCBI Sequence Viewer  
  XP_013964297 (Get FASTA)   NCBI Sequence Viewer  
  XP_013964299 (Get FASTA)   NCBI Sequence Viewer  
  XP_022265842 (Get FASTA)   NCBI Sequence Viewer  
  XP_038315763 (Get FASTA)   NCBI Sequence Viewer  
  XP_038315767 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325881 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325882 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325883 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325884 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325885 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325886 (Get FASTA)   NCBI Sequence Viewer  
  XP_038325887 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386689 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386691 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386692 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386693 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386694 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386695 (Get FASTA)   NCBI Sequence Viewer  
  XP_038386696 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450914 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450915 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450916 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450917 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450918 (Get FASTA)   NCBI Sequence Viewer  
  XP_038450919 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514988 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514989 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514990 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514991 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514992 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514993 (Get FASTA)   NCBI Sequence Viewer  
  XP_038514994 (Get FASTA)   NCBI Sequence Viewer  
  XP_544363 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAH22452 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000011322.3
  ENSCAFP00000043843.2
  ENSCAFP00000045130.2
  ENSCAFP00030005308.1
  ENSCAFP00030005363.1
  ENSCAFP00030005398.1
  ENSCAFP00030005431.1
  ENSCAFP00030005478.1
  ENSCAFP00030005499.1
  ENSCAFP00040005990.1
  ENSCAFP00040006012.1
  ENSCAFP00040006035.1
  ENSCAFP00040006064.1
  ENSCAFP00845016363
  ENSCAFP00845016363.1
  ENSCAFP00845016412
  ENSCAFP00845016412.1
  ENSCAFP00845016464
  ENSCAFP00845016464.1
RefSeq Acc Id: XP_013964297   ⟸   XM_014108822
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013964299   ⟸   XM_014108824
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003433863   ⟸   XM_003433815
- Peptide Label: isoform X1
- UniProtKB: A0A8I3NJ30 (UniProtKB/TrEMBL),   A0A8P0NVD8 (UniProtKB/TrEMBL),   A0A8C0M2S6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_544363   ⟸   XM_544363
- Peptide Label: isoform X3
- UniProtKB: A0A8C0PYF3 (UniProtKB/TrEMBL),   A0A8I3NK93 (UniProtKB/TrEMBL),   A0A8C0M2S6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022265842   ⟸   XM_022410134
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000061390   ⟸   ENSCAFT00000074878
RefSeq Acc Id: ENSCAFP00000045130   ⟸   ENSCAFT00000068054
RefSeq Acc Id: ENSCAFP00000043843   ⟸   ENSCAFT00000076972
RefSeq Acc Id: ENSCAFP00000011322   ⟸   ENSCAFT00000012216
RefSeq Acc Id: ENSCAFP00000054020   ⟸   ENSCAFT00000061673
RefSeq Acc Id: XP_038325881   ⟸   XM_038469953
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325883   ⟸   XM_038469955
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325882   ⟸   XM_038469954
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325885   ⟸   XM_038469957
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325884   ⟸   XM_038469956
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038325887   ⟸   XM_038469959
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038325886   ⟸   XM_038469958
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038450914   ⟸   XM_038594986
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450916   ⟸   XM_038594988
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450915   ⟸   XM_038594987
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450918   ⟸   XM_038594990
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450917   ⟸   XM_038594989
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038450919   ⟸   XM_038594991
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038514988   ⟸   XM_038659060
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514990   ⟸   XM_038659062
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514989   ⟸   XM_038659061
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514992   ⟸   XM_038659064
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514991   ⟸   XM_038659063
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514994   ⟸   XM_038659066
- Peptide Label: isoform X1
- UniProtKB: A0A8I3NJ30 (UniProtKB/TrEMBL),   A0A8P0NVD8 (UniProtKB/TrEMBL),   A0A8C0M2S6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038514993   ⟸   XM_038659065
- Peptide Label: isoform X3
- UniProtKB: A0A8C0PYF3 (UniProtKB/TrEMBL),   A0A8I3NK93 (UniProtKB/TrEMBL),   A0A8C0M2S6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315763   ⟸   XM_038459835
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038315767   ⟸   XM_038459839
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL),   A0A8C0M2N8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386689   ⟸   XM_038530761
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M2N8 (UniProtKB/TrEMBL),   A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386692   ⟸   XM_038530764
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M2N8 (UniProtKB/TrEMBL),   A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386691   ⟸   XM_038530763
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M2N8 (UniProtKB/TrEMBL),   A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386694   ⟸   XM_038530766
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M2N8 (UniProtKB/TrEMBL),   A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386693   ⟸   XM_038530765
- Peptide Label: isoform X2
- UniProtKB: A0A8C0M2N8 (UniProtKB/TrEMBL),   A0A8C0M840 (UniProtKB/TrEMBL),   A0A8C0R439 (UniProtKB/TrEMBL),   A0A8I3N971 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386696   ⟸   XM_038530768
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M2S6 (UniProtKB/TrEMBL),   A0A8I3NJ30 (UniProtKB/TrEMBL),   A0A8P0NVD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386695   ⟸   XM_038530767
- Peptide Label: isoform X3
- UniProtKB: A0A8C0M2S6 (UniProtKB/TrEMBL),   A0A8C0PYF3 (UniProtKB/TrEMBL),   A0A8I3NK93 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845016412   ⟸   ENSCAFT00845020896
RefSeq Acc Id: ENSCAFP00845016464   ⟸   ENSCAFT00845020954
RefSeq Acc Id: ENSCAFP00845016363   ⟸   ENSCAFT00845020842
Protein Domains
Rho-GAP   SH2   SH3

Promoters
RGD ID:13682489
Promoter ID:EPDNEW_C557
Type:single initiation site
Name:PIK3R1_1
Description:phosphoinositide-3-kinase regulatory subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1253,456,156 - 53,456,216EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007626 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030003178 UniProtKB/TrEMBL
  ENSCAFG00040003559 UniProtKB/TrEMBL
  ENSCAFG00845011717 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012216.5 UniProtKB/TrEMBL
  ENSCAFT00000068054.2 UniProtKB/TrEMBL
  ENSCAFT00000076972.2 UniProtKB/TrEMBL
  ENSCAFT00030006010.1 UniProtKB/TrEMBL
  ENSCAFT00030006077.1 UniProtKB/TrEMBL
  ENSCAFT00030006121.1 UniProtKB/TrEMBL
  ENSCAFT00030006167.1 UniProtKB/TrEMBL
  ENSCAFT00030006218.1 UniProtKB/TrEMBL
  ENSCAFT00030006241.1 UniProtKB/TrEMBL
  ENSCAFT00040006903.1 UniProtKB/TrEMBL
  ENSCAFT00040006929.1 UniProtKB/TrEMBL
  ENSCAFT00040006954.1 UniProtKB/TrEMBL
  ENSCAFT00040006983.1 UniProtKB/TrEMBL
  ENSCAFT00845020842 ENTREZGENE
  ENSCAFT00845020842.1 UniProtKB/TrEMBL
  ENSCAFT00845020896 ENTREZGENE
  ENSCAFT00845020896.1 UniProtKB/TrEMBL
  ENSCAFT00845020954 ENTREZGENE
  ENSCAFT00845020954.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro ISH2_PIK3R1 UniProtKB/TrEMBL
  PI3K_P85_iSH2 UniProtKB/TrEMBL
  PI3K_p85alpha_SH3 UniProtKB/TrEMBL
  PI3kinase_P85_cSH2 UniProtKB/TrEMBL
  PI3kinase_P85_nSH2 UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
KEGG Report cfa:487235 UniProtKB/TrEMBL
NCBI Gene PIK3R1 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT UniProtKB/TrEMBL
  PI3K21B, ISOFORM B UniProtKB/TrEMBL
  SUPPRESSOR OF CYTOKINE SIGNALING AT 16D, ISOFORM B UniProtKB/TrEMBL
Pfam PI3K_P85_iSH2 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PRINTS PI3KINASEP85 UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/TrEMBL
PROSITE RHOGAP UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt A0A8C0M2K8_CANLF UniProtKB/TrEMBL
  A0A8C0M2N8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M2S6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0M840 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PYF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q5A5_CANLF UniProtKB/TrEMBL
  A0A8C0R439 ENTREZGENE
  A0A8C0RBQ5_CANLF UniProtKB/TrEMBL
  A0A8I3N971 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NJ30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NK93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NVD8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44560 ENTREZGENE