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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sarin
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Accession:CHEBI:75701 term browser browse the term
Definition:A racemate composed of equal amounts of (R)- and (S)-sarin. A potent and irreversible inhibitor of acetylcholinesterase that is toxic to the nervous system and is employed as a chemical warfare agent.
Synonyms:exact_synonym: rac-propan-2-yl methylphosphonofluoridate
 related_synonym: (+-)-isopropyl methylphosphonofluoridate;   (RS)-isopropyl methylphosphonofluoridate;   (RS)-sarin;   Isopropoxymethylphosphoryl fluoride;   Isopropyl methanefluorophosphonate;   Isopropyl methylfluorophosphate;   Methlyfluorophosphonic acid isopropyl ester;   Methylphosphonofluoridic acid isopropyl ester;   o-Isopropyl methylphosphonofluoridate;   rac-isopropyl methylphosphonofluoridate;   racemic sarin
 alt_id: CHEBI:9030
 xref: CAS:107-44-8;   KEGG:C11764
 xref_mesh: MESH:D012524
 xref: PMID:23052190;   PMID:23054072;   PMID:23159884;   PMID:23200942;   PMID:23205740;   PMID:23263315;   PMID:23692952;   PMID:23963476;   PMID:23999806;   Patent:US4108950;   Patent:US4292308;   Patent:WO2005051297;   Reaxys:1750114;   Wikipedia:Sarin


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sarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 decreases expression EXP Sarin results in decreased expression of ABCB1 mRNA CTD PMID:19522546 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323 		JBrowse link
G ABCD3 ATP binding cassette subfamily D member 3 decreases expression EXP Sarin results in decreased expression of ABCD3 mRNA CTD PMID:19522546 NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666 		JBrowse link
G ABCF2 ATP binding cassette subfamily F member 2 decreases expression
increases expression		 EXP Sarin results in decreased expression of ABCF2 mRNA
Sarin results in increased expression of ABCF2 mRNA		 CTD PMID:19522546 NCBI chr 7:151,211,484...151,227,205
Ensembl chr 7:151,211,484...151,227,205 		JBrowse link
G ACAA2 acetyl-CoA acyltransferase 2 decreases expression EXP Sarin results in decreased expression of ACAA2 mRNA CTD PMID:19522546 NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953 		JBrowse link
G ACAT2 acetyl-CoA acetyltransferase 2 decreases expression
increases expression		 EXP Sarin results in decreased expression of ACAT2 mRNA
Sarin results in increased expression of ACAT2 mRNA		 CTD PMID:19522546 NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112 		JBrowse link
G ACHE acetylcholinesterase (Yt blood group) multiple interactions
affects binding
affects expression
increases phosphorylation
decreases activity
increases metabolic processing
increases activity
decreases expression		 EXP
ISO		 1-((4-(aminocarbonyl)pyridinio)trimethylene)-2-((hydroxyimino)methyl)pyridinium inhibits the reaction [Sarin results in decreased activity of ACHE protein]; 4-amino-2-((diethylamino)methyl)phenol analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with asoxime chloride] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride affects the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; benzohydroxamic acid analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Donepezil promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; HLo 7 affects the reaction [Sarin results in decreased activity of ACHE protein]; Imipramine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Imipramine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; isonitrosoacetone inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; isonitrosoacetone inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-p-xylene-bis-((2,2'-hydroxyiminomethyl)pyridinium) dibromide inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pralidoxime Compounds inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pyridine-4-aldoxime analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; RS194B analog inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS41A inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Sarin binds to and results in decreased activity of ACHE protein; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]
asoxime chloride binds to [Sarin binds to ACHE protein]
Sarin affects the expression of ACHE mRNA
Sarin results in increased phosphorylation of ACHE protein
Sarin analog results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein
4-(ethylcarboxyl)-2'-(hydroxyiminomethyl)-1,1'-(phenylene-1,3-diyl)-bispyridinium inhibits the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; BI 6 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N(6)-cyclopentyladenosine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; naphthylene-2,7-diyl-bis(2-hydroxyiminomethylpyridinium) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Physostigmine affects the reaction [Sarin affects the expression of ACHE mRNA]; Physostigmine affects the reaction [Sarin affects the expression of and affects the activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pyridinium Compounds inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Sarin affects the expression of and affects the activity of ACHE protein; Trimedoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]
Sarin analog results in decreased activity of ACHE protein; Sarin metabolite results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Sarin binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein
Sarin results in increased metabolism of ACHE protein; Sarin results in increased metabolism of ACHE protein mutant form
Sarin results in increased activity of ACHE protein
Sarin results in decreased expression of ACHE mRNA		 CTD PMID:1609424 PMID:12415428 PMID:14631503 PMID:16025528 PMID:17370251 More... NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974 		JBrowse link
G ACLY ATP citrate lyase decreases expression EXP Sarin results in decreased expression of ACLY mRNA CTD PMID:19522546 NCBI chr17:41,866,917...41,930,545
Ensembl chr17:41,866,917...41,930,542 		JBrowse link
G ADD1 adducin 1 decreases expression EXP Sarin results in decreased expression of ADD1 mRNA CTD PMID:19522546 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076 		JBrowse link
G ADORA1 adenosine A1 receptor increases expression EXP Sarin results in increased expression of ADORA1 mRNA CTD PMID:19522546 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G ADORA2A adenosine A2a receptor decreases expression EXP Sarin results in decreased expression of ADORA2A mRNA CTD PMID:19522546 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G AGRN agrin decreases expression EXP Sarin results in decreased expression of AGRN mRNA CTD PMID:19522546 NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,118 		JBrowse link
G AHCY adenosylhomocysteinase decreases expression EXP Sarin results in decreased expression of AHCY mRNA CTD PMID:19522546 NCBI chr20:34,231,981...34,311,836
Ensembl chr20:34,280,268...34,311,802 		JBrowse link
G AK1 adenylate kinase 1 decreases expression ISO Sarin results in decreased expression of AK1 protein CTD PMID:28973502 NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675 		JBrowse link
G AK3 adenylate kinase 3 decreases expression EXP Sarin results in decreased expression of AK3 mRNA CTD PMID:19522546 NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043 		JBrowse link
G AKAP9 A-kinase anchoring protein 9 decreases expression
increases expression		 EXP Sarin results in decreased expression of AKAP9 mRNA
Sarin results in increased expression of AKAP9 mRNA		 CTD PMID:19522546 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673 		JBrowse link
G ALB albumin affects binding
increases expression		 EXP
ISO		 Sarin binds to ALB protein
Sarin results in increased expression of ALB protein		 CTD PMID:17188226 PMID:28973502 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A decreases expression EXP Sarin results in decreased expression of ALDOA mRNA CTD PMID:19522546 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457 		JBrowse link
G ALDOC aldolase, fructose-bisphosphate C affects expression ISO Sarin affects the expression of ALDOC protein CTD PMID:28973502 NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948 		JBrowse link
G AMACR alpha-methylacyl-CoA racemase decreases expression EXP Sarin results in decreased expression of AMACR mRNA CTD PMID:19522546 NCBI chr 5:33,986,165...34,008,050
Ensembl chr 5:33,986,165...34,008,104 		JBrowse link
G APBB3 amyloid beta precursor protein binding family B member 3 increases expression EXP Sarin results in increased expression of APBB3 mRNA CTD PMID:19522546 NCBI chr 5:140,558,268...140,564,598
Ensembl chr 5:140,558,268...140,564,781 		JBrowse link
G APLP1 amyloid beta precursor like protein 1 increases expression EXP Sarin results in increased expression of APLP1 mRNA CTD PMID:19522546 NCBI chr19:35,868,574...35,879,792
Ensembl chr19:35,867,899...35,879,792 		JBrowse link
G APOA1 apolipoprotein A1 decreases expression ISO Sarin results in decreased expression of APOA1 protein CTD PMID:26778279 NCBI chr11:116,835,751...116,837,950
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOC4 apolipoprotein C4 increases expression EXP Sarin results in increased expression of APOC4 mRNA CTD PMID:19522546 NCBI chr19:44,942,237...44,945,496
Ensembl chr19:44,942,237...44,945,496 		JBrowse link
G APOE apolipoprotein E increases expression EXP Sarin results in increased expression of APOE mRNA; Sarin results in increased expression of APOE protein CTD PMID:19522546 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APP amyloid beta precursor protein decreases expression EXP Sarin results in decreased expression of APP mRNA CTD PMID:19522546 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G ARPC5L actin related protein 2/3 complex subunit 5 like increases expression ISO Sarin results in increased expression of ARPC5L protein CTD PMID:28973502 NCBI chr 9:124,862,130...124,877,733
Ensembl chr 9:124,862,130...124,877,733 		JBrowse link
G ASCL1 achaete-scute family bHLH transcription factor 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of ASCL1 mRNA
Sarin results in increased expression of ASCL1 mRNA		 CTD PMID:19522546 NCBI chr12:102,957,674...102,960,513
Ensembl chr12:102,957,674...102,960,513 		JBrowse link
G ASL argininosuccinate lyase decreases expression EXP Sarin results in decreased expression of ASL mRNA CTD PMID:19522546 NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Sarin results in decreased expression of ATP1B1 mRNA CTD PMID:19522546 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992 		JBrowse link
G ATP5PD ATP synthase peripheral stalk subunit d decreases expression ISO Sarin results in decreased expression of ATP5PD protein CTD PMID:28973502 NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985 		JBrowse link
G ATP5PO ATP synthase peripheral stalk subunit OSCP decreases expression EXP Sarin results in decreased expression of ATP5PO mRNA CTD PMID:19522546 NCBI chr21:33,903,453...33,915,804
Ensembl chr21:33,903,453...33,915,814 		JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 decreases expression EXP Sarin results in decreased expression of ATP6V0A2 mRNA CTD PMID:19522546 NCBI chr12:123,712,353...123,761,755
Ensembl chr12:123,712,353...123,761,755 		JBrowse link
G ATP6V0E1 ATPase H+ transporting V0 subunit e1 decreases expression EXP Sarin results in decreased expression of ATP6V0E mRNA CTD PMID:19522546 NCBI chr 5:172,983,771...173,035,445
Ensembl chr 5:172,983,771...173,035,445 		JBrowse link
G ATP9B ATPase phospholipid transporting 9B (putative) increases expression EXP Sarin results in increased expression of ATP9B mRNA CTD PMID:19522546 NCBI chr18:79,069,394...79,378,283
Ensembl chr18:79,069,285...79,378,287 		JBrowse link
G B2M beta-2-microglobulin decreases expression EXP Sarin results in decreased expression of B2M mRNA CTD PMID:19522546 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BAG1 BAG cochaperone 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of BAG1 mRNA
Sarin results in increased expression of BAG1 mRNA		 CTD PMID:19522546 NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
affects expression		 EXP
ISO		 Sarin results in increased expression of BAX mRNA
Sarin affects the expression of BAX mRNA; Sarin affects the expression of BAX protein		 CTD PMID:19522546 PMID:27639427 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCHE butyrylcholinesterase multiple interactions
decreases activity
decreases response to substance
increases phosphorylation
decreases expression
affects binding		 EXP
ISO		 asoxime chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of BCHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sarin analog promotes the reaction [Sarin binds to BCHE protein]
Physostigmine inhibits the reaction [Sarin results in decreased activity of BCHE protein]
BCHE protein results in decreased susceptibility to Sarin
Sarin results in increased phosphorylation of BCHE protein
Sarin results in decreased expression of BCHE mRNA
Sarin analog results in decreased activity of BCHE protein; Sarin metabolite results in decreased activity of BCHE protein; Sarin results in decreased activity of BCHE protein		 CTD PMID:17698511 PMID:18617161 PMID:19283689 PMID:19428953 PMID:19522546 More... NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression
decreases expression		 ISO Sarin results in increased expression of BCL2 mRNA
Sarin results in decreased expression of BCL2 protein		 CTD PMID:27639427 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of BCL2L1 mRNA
Sarin results in increased expression of BCL2L1 mRNA		 CTD PMID:19522546 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BEX3 brain expressed X-linked 3 decreases expression EXP Sarin results in decreased expression of BEX3 mRNA CTD PMID:19522546 NCBI chr  X:103,376,323...103,378,164
Ensembl chr  X:103,376,395...103,378,164 		JBrowse link
G BPTF bromodomain PHD finger transcription factor increases expression EXP Sarin results in increased expression of BPTF mRNA CTD PMID:19522546 NCBI chr17:67,825,503...67,984,378
Ensembl chr17:67,825,503...67,984,378 		JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 decreases expression
increases expression		 EXP Sarin results in decreased expression of CACNG4 mRNA
Sarin results in increased expression of CACNG4 mRNA		 CTD PMID:19522546 NCBI chr17:66,964,707...67,033,398
Ensembl chr17:66,964,707...67,033,398 		JBrowse link
G CALM1 calmodulin 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of CALM1 mRNA
Sarin results in increased expression of CALM1 mRNA		 CTD PMID:19522546 NCBI chr14:90,396,502...90,408,268
Ensembl chr14:90,396,502...90,408,268 		JBrowse link
G CALM3 calmodulin 3 decreases expression EXP Sarin results in decreased expression of CALM3 mRNA CTD PMID:19522546 NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782 		JBrowse link
G CAPN1 calpain 1 increases expression ISO Sarin results in increased expression of CAPN1 protein CTD PMID:21439362 NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006 		JBrowse link
G CASP4 caspase 4 increases expression EXP Sarin results in increased expression of CASP4 mRNA CTD PMID:19522546 NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 increases expression EXP Sarin results in increased expression of CCR1 mRNA CTD PMID:19522546 NCBI chr 3:46,201,711...46,208,313
Ensembl chr 3:46,201,711...46,208,313 		JBrowse link
G CD24 CD24 molecule decreases expression
increases expression		 EXP Sarin results in decreased expression of CD24 mRNA
Sarin results in increased expression of CD24 mRNA		 CTD PMID:19522546 NCBI chr 6:106,969,831...106,976,855
Ensembl chr 6:106,969,831...106,975,627 		JBrowse link
G CD9 CD9 molecule decreases expression EXP Sarin results in decreased expression of CD9 mRNA; Sarin results in decreased expression of CD9 protein CTD PMID:19522546 NCBI chr12:6,199,946...6,238,266
Ensembl chr12:6,199,715...6,238,271 		JBrowse link
G CDK5 cyclin dependent kinase 5 decreases expression
increases expression		 EXP Sarin results in decreased expression of CDK5 mRNA
Sarin results in increased expression of CDK5 mRNA		 CTD PMID:19522546 NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897 		JBrowse link
G CEPT1 choline/ethanolamine phosphotransferase 1 increases expression EXP Sarin results in increased expression of CEPT1 mRNA CTD PMID:19522546 NCBI chr 1:111,139,499...111,185,104
Ensembl chr 1:111,139,479...111,185,104 		JBrowse link
G CES1 carboxylesterase 1 multiple interactions EXP CES1 protein affects the metabolism of and results in decreased activity of Sarin CTD PMID:12679808 NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator increases expression EXP Sarin results in increased expression of CFLAR mRNA CTD PMID:19522546 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CHAT choline O-acetyltransferase decreases expression ISO Sarin results in decreased expression of CHAT protein CTD PMID:22640809 NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942 		JBrowse link
G CHRM2 cholinergic receptor muscarinic 2 affects activity
multiple interactions
decreases expression		 ISO Sarin affects the activity of CHRM2 protein
Sarin inhibits the reaction [AFDX 384 binds to CHRM2 protein]
Sarin results in decreased expression of CHRM2 protein		 CTD PMID:21419149 PMID:29128314 NCBI chr 7:136,868,652...137,020,213
Ensembl chr 7:136,868,652...137,020,255 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit decreases expression EXP Sarin results in decreased expression of CHRNA3 mRNA CTD PMID:19522546 NCBI chr15:78,593,052...78,620,996
Ensembl chr15:78,593,052...78,621,295 		JBrowse link
G CHRNB1 cholinergic receptor nicotinic beta 1 subunit decreases expression EXP Sarin results in decreased expression of CHRNB1 mRNA CTD PMID:19522546 NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit decreases expression EXP Sarin results in decreased expression of CHRNB4 mRNA CTD PMID:19522546 NCBI chr15:78,624,111...78,661,641
Ensembl chr15:78,624,111...78,727,754 		JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit increases expression EXP Sarin results in increased expression of CHRNE mRNA CTD PMID:19522546 NCBI chr17:4,897,771...4,908,677
Ensembl chr17:4,897,771...4,934,438 		JBrowse link
G CKLF chemokine like factor decreases expression
increases expression		 EXP Sarin results in decreased expression of CKLF mRNA
Sarin results in increased expression of CKLF mRNA		 CTD PMID:19522546 NCBI chr16:66,552,563...66,566,287
Ensembl chr16:66,552,563...66,566,251 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 decreases expression EXP Sarin results in decreased expression of CLCN3 mRNA CTD PMID:19522546 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673 		JBrowse link
G CLNS1A chloride nucleotide-sensitive channel 1A decreases expression EXP Sarin results in decreased expression of CLNS1A mRNA CTD PMID:19522546 NCBI chr11:77,614,530...77,637,794
Ensembl chr11:77,514,936...77,637,794 		JBrowse link
G CLU clusterin decreases expression EXP Sarin results in decreased expression of CLU mRNA CTD PMID:19522546 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CNR2 cannabinoid receptor 2 increases expression EXP Sarin results in increased expression of CNR2 mRNA CTD PMID:19522546 NCBI chr 1:23,870,515...23,913,362
Ensembl chr 1:23,870,515...23,913,362 		JBrowse link
G COL3A1 collagen type III alpha 1 chain decreases expression EXP Sarin results in decreased expression of COL3A1 mRNA CTD PMID:19522546 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G CORO1A coronin 1A decreases expression ISO Sarin results in decreased expression of CORO1A protein CTD PMID:28973502 NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076 		JBrowse link
G COX15 cytochrome c oxidase assembly homolog COX15 decreases expression
increases expression		 EXP Sarin results in decreased expression of COX15 mRNA
Sarin results in increased expression of COX15 mRNA		 CTD PMID:19522546 NCBI chr10:99,694,293...99,732,127
Ensembl chr10:99,710,868...99,732,127 		JBrowse link
G COX5A cytochrome c oxidase subunit 5A decreases expression ISO Sarin results in decreased expression of COX5A protein CTD PMID:28973502 NCBI chr15:74,919,791...74,938,073
Ensembl chr15:74,919,791...74,938,083 		JBrowse link
G COX5B cytochrome c oxidase subunit 5B decreases expression ISO Sarin results in decreased expression of COX5B protein CTD PMID:28973502 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383 		JBrowse link
G COX6A1 cytochrome c oxidase subunit 6A1 decreases expression
increases expression		 EXP
ISO		 Sarin results in decreased expression of COX6A1 mRNA
Sarin results in increased expression of COX6A1 protein		 CTD PMID:19522546 PMID:28973502 NCBI chr12:120,438,113...120,440,730
Ensembl chr12:120,438,090...120,440,737 		JBrowse link
G CPLX2 complexin 2 decreases expression ISO Sarin results in decreased expression of CPLX2 protein CTD PMID:28973502 NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021 		JBrowse link
G CREB3 cAMP responsive element binding protein 3 decreases expression EXP Sarin results in decreased expression of CREB3 mRNA CTD PMID:19522546 NCBI chr 9:35,732,666...35,736,999
Ensembl chr 9:35,732,598...35,736,999 		JBrowse link
G CST3 cystatin C decreases expression EXP Sarin results in decreased expression of CST3 mRNA CTD PMID:19522546 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473 		JBrowse link
G CSTB cystatin B decreases expression
increases expression		 EXP Sarin results in decreased expression of CSTB mRNA
Sarin results in increased expression of CSTB mRNA		 CTD PMID:19522546 NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330 		JBrowse link
G CTSD cathepsin D decreases expression EXP Sarin results in decreased expression of CTSD mRNA CTD PMID:19522546 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G CUL4B cullin 4B decreases expression
increases expression		 EXP Sarin results in decreased expression of CUL4B mRNA
Sarin results in increased expression of CUL4B mRNA		 CTD PMID:19522546 NCBI chr  X:120,523,858...120,575,532
Ensembl chr  X:120,505,920...120,604,074 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 decreases expression EXP Sarin results in decreased expression of CXCR4 mRNA CTD PMID:19522546 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYC1 cytochrome c1 increases expression EXP Sarin results in increased expression of CYC1 mRNA CTD PMID:19522546 NCBI chr 8:144,095,076...144,097,525
Ensembl chr 8:144,095,039...144,097,525 		JBrowse link
G DAG1 dystroglycan 1 decreases expression EXP Sarin results in decreased expression of DAG1 mRNA CTD PMID:19522546 NCBI chr 3:49,468,948...49,535,615
Ensembl chr 3:49,468,713...49,535,618 		JBrowse link
G DBH dopamine beta-hydroxylase decreases expression EXP Sarin results in decreased expression of DBH mRNA CTD PMID:19522546 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329 		JBrowse link
G DBN1 drebrin 1 decreases expression EXP Sarin results in decreased expression of DBN1 mRNA CTD PMID:19522546 NCBI chr 5:177,456,610...177,473,634
Ensembl chr 5:177,456,608...177,474,401 		JBrowse link
G DCTN2 dynactin subunit 2 increases expression ISO Sarin results in increased expression of DCTN2 protein CTD PMID:28973502 NCBI chr12:57,530,051...57,547,192
Ensembl chr12:57,529,633...57,547,224 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 affects expression ISO Sarin affects the expression of DDAH1 protein CTD PMID:28973502 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363 		JBrowse link
G DDC dopa decarboxylase decreases expression
affects binding		 EXP Sarin results in decreased expression of DDC mRNA; Sarin results in decreased expression of DDC protein
Sarin binds to [DDC protein binds to Pyridoxal Phosphate]; Sarin binds to DDC protein		 CTD PMID:19522546 PMID:35151785 NCBI chr 7:50,458,442...50,565,405
Ensembl chr 7:50,458,436...50,565,405 		JBrowse link
G DGUOK deoxyguanosine kinase decreases expression
increases expression		 EXP Sarin results in decreased expression of DGUOK mRNA
Sarin results in increased expression of DGUOK mRNA		 CTD PMID:19522546 NCBI chr 2:73,926,880...73,958,946
Ensembl chr 2:73,926,826...73,958,961 		JBrowse link
G DLD dihydrolipoamide dehydrogenase decreases expression ISO Sarin results in decreased expression of DLD protein CTD PMID:28973502 NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730 		JBrowse link
G DLK1 delta like non-canonical Notch ligand 1 decreases expression EXP Sarin results in decreased expression of DLK1 mRNA CTD PMID:19522546 NCBI chr14:100,726,892...100,738,224
Ensembl chr14:100,725,705...100,738,224 		JBrowse link
G DLST dihydrolipoamide S-succinyltransferase decreases expression ISO Sarin results in decreased expression of DLST protein CTD PMID:28973502 NCBI chr14:74,881,916...74,903,743
Ensembl chr14:74,881,891...74,903,743 		JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression
increases expression		 EXP Sarin results in decreased expression of DNAJA1 mRNA
Sarin results in increased expression of DNAJA1 mRNA		 CTD PMID:19522546 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 decreases expression EXP Sarin results in decreased expression of DNAJB2 mRNA CTD PMID:19522546 NCBI chr 2:219,279,366...219,286,895
Ensembl chr 2:219,279,342...219,286,898 		JBrowse link
G DRD5 dopamine receptor D5 increases expression EXP Sarin results in increased expression of DRD5 mRNA CTD PMID:19522546 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G DYNLL1 dynein light chain LC8-type 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of DYNLL1 mRNA
Sarin results in increased expression of DYNLL1 mRNA		 CTD PMID:19522546 NCBI chr12:120,469,842...120,498,493
Ensembl chr12:120,469,850...120,498,493 		JBrowse link
G EFNA4 ephrin A4 decreases expression EXP Sarin results in decreased expression of EFNA4 mRNA CTD PMID:19522546 NCBI chr 1:155,063,740...155,069,553
Ensembl chr 1:155,063,737...155,069,553 		JBrowse link
G EID1 EP300 interacting inhibitor of differentiation 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of EID1 mRNA
Sarin results in increased expression of EID1 mRNA		 CTD PMID:19522546 NCBI chr15:48,878,134...48,880,173
Ensembl chr15:48,878,134...48,880,173 		JBrowse link
G EIF2B1 eukaryotic translation initiation factor 2B subunit alpha decreases expression EXP Sarin results in decreased expression of EIF2B1 mRNA CTD PMID:19522546 NCBI chr12:123,620,406...123,633,686
Ensembl chr12:123,620,406...123,633,766 		JBrowse link
G ELP1 elongator acetyltransferase complex subunit 1 decreases expression EXP Sarin results in decreased expression of ELP1 mRNA CTD PMID:19522546 NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328 		JBrowse link
G ENO1 enolase 1 decreases expression ISO Sarin results in decreased expression of ENO1 protein CTD PMID:28973502 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ENO2 enolase 2 decreases expression ISO Sarin results in decreased expression of ENO2 protein CTD PMID:28973502 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 decreases expression EXP Sarin results in decreased expression of ENTPD8 mRNA CTD PMID:19522546 NCBI chr 9:137,434,364...137,441,357
Ensembl chr 9:137,434,364...137,441,816 		JBrowse link
G ETFB electron transfer flavoprotein subunit beta decreases expression
increases expression		 EXP Sarin results in decreased expression of ETFB mRNA
Sarin results in increased expression of ETFB mRNA		 CTD PMID:19522546 NCBI chr19:51,345,155...51,366,388
Ensembl chr19:51,345,169...51,366,388 		JBrowse link
G ETS2 ETS proto-oncogene 2, transcription factor increases expression EXP Sarin results in increased expression of ETS2 mRNA; Sarin results in increased expression of ETS2 protein CTD PMID:19522546 NCBI chr21:38,805,183...38,824,955
Ensembl chr21:38,805,183...38,824,955 		JBrowse link
G F12 coagulation factor XII decreases expression EXP Sarin results in decreased expression of F12 mRNA CTD PMID:19522546 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583 		JBrowse link
G FABP5 fatty acid binding protein 5 decreases expression ISO Sarin results in decreased expression of FABP5 protein CTD PMID:28973502 NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777 		JBrowse link
G FBLN1 fibulin 1 decreases expression EXP Sarin results in decreased expression of FBLN1 mRNA CTD PMID:19522546 NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135 		JBrowse link
G FCER1A Fc epsilon receptor Ia increases expression EXP Sarin results in increased expression of FCER1A mRNA CTD PMID:19522546 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224 		JBrowse link
G FEV FEV transcription factor, ETS family member decreases expression
increases expression		 EXP Sarin results in decreased expression of FEV mRNA
Sarin results in increased expression of FEV mRNA		 CTD PMID:19522546 NCBI chr 2:218,981,087...218,985,184
Ensembl chr 2:218,981,087...218,985,184 		JBrowse link
G FTH1 ferritin heavy chain 1 decreases expression EXP Sarin results in decreased expression of FTH1 mRNA CTD PMID:19522546 NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634 		JBrowse link
G GABARAP GABA type A receptor-associated protein decreases expression
increases expression		 EXP Sarin results in decreased expression of GABARAP mRNA
Sarin results in increased expression of GABARAP mRNA		 CTD PMID:19522546 NCBI chr17:7,240,008...7,242,449
Ensembl chr17:7,240,008...7,242,449 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 increases expression EXP Sarin results in increased expression of GABRG3 mRNA CTD PMID:19522546 NCBI chr15:26,971,181...27,541,984
Ensembl chr15:26,971,181...27,541,984 		JBrowse link
G GABRR1 gamma-aminobutyric acid type A receptor subunit rho1 decreases expression EXP Sarin results in decreased expression of GABRR1 mRNA CTD PMID:19522546 NCBI chr 6:89,177,504...89,231,288
Ensembl chr 6:89,177,504...89,231,278 		JBrowse link
G GAD1 glutamate decarboxylase 1 affects binding EXP Sarin binds to [GAD1 protein binds to Pyridoxal Phosphate]; Sarin binds to GAD1 protein CTD PMID:35151785 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151 		JBrowse link
G GAD2 glutamate decarboxylase 2 affects binding EXP Sarin binds to [GAD2 protein binds to Pyridoxal Phosphate]; Sarin binds to GAD2 protein CTD PMID:35151785 NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP Sarin results in increased expression of GADD45A mRNA CTD PMID:19522546 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GAP43 growth associated protein 43 decreases expression EXP Sarin results in decreased expression of GAP43 mRNA CTD PMID:19522546 NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490 		JBrowse link
G GC GC vitamin D binding protein increases expression ISO Sarin results in increased expression of GC protein CTD PMID:26778279 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GCH1 GTP cyclohydrolase 1 decreases expression EXP Sarin results in decreased expression of GCH1 mRNA CTD PMID:19522546 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions
increases expression		 ISO 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein
Sarin results in increased expression of GFAP protein		 CTD PMID:23692952 PMID:27639427 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GLO1 glyoxalase I increases expression ISO Sarin results in increased expression of GLO1 protein CTD PMID:28973502 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145 		JBrowse link
G GLRA1 glycine receptor alpha 1 increases expression EXP Sarin results in increased expression of GLRA1 mRNA CTD PMID:19522546 NCBI chr 5:151,822,513...151,924,851
Ensembl chr 5:151,822,513...151,924,851 		JBrowse link
G GLS glutaminase decreases expression EXP Sarin results in decreased expression of GLS mRNA CTD PMID:19522546 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 decreases expression EXP Sarin results in decreased expression of GLUD1 mRNA CTD PMID:19522546 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843 		JBrowse link
G GLUL glutamate-ammonia ligase decreases expression
increases expression		 EXP
ISO		 Sarin results in decreased expression of GLUL mRNA
Sarin results in decreased expression of GLNS protein
Sarin results in increased expression of GLUL mRNA		 CTD PMID:19522546 PMID:28973502 NCBI chr 1:182,378,098...182,391,790
Ensembl chr 1:182,378,098...182,392,206 		JBrowse link
G GNAS GNAS complex locus decreases expression EXP Sarin results in decreased expression of GNAS mRNA CTD PMID:19522546 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GPI glucose-6-phosphate isomerase decreases expression EXP Sarin results in decreased expression of GPI mRNA CTD PMID:19522546 NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413 		JBrowse link
G GPR27 G protein-coupled receptor 27 increases expression EXP Sarin results in increased expression of GPR27 mRNA CTD PMID:19522546 NCBI chr 3:71,753,855...71,756,496
Ensembl chr 3:71,753,855...71,756,496 		JBrowse link
G GRIK5 glutamate ionotropic receptor kainate type subunit 5 increases expression EXP Sarin results in increased expression of GRIK5 mRNA CTD PMID:19522546 NCBI chr19:41,998,324...42,070,206
Ensembl chr19:41,998,321...42,070,206 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B increases expression EXP Sarin results in increased expression of GRIN2B mRNA CTD PMID:19522546 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 decreases expression EXP Sarin results in decreased expression of GSTA4 mRNA CTD PMID:19522546 NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304 		JBrowse link
G GSTM5 glutathione S-transferase mu 5 increases expression EXP Sarin results in increased expression of GSTM5 mRNA CTD PMID:19522546 NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,780...109,775,428 		JBrowse link
G GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) decreases expression EXP Sarin results in decreased expression of GSTT2 mRNA CTD PMID:19522546 NCBI chr22:23,980,134...23,983,915
Ensembl chr22:23,980,058...23,983,915 		JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 decreases expression EXP Sarin results in decreased expression of GSTZ1 mRNA CTD PMID:19522546 NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597 		JBrowse link
G HADHA hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Sarin results in decreased expression of HADHA mRNA CTD PMID:19522546 NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672 		JBrowse link
G HBA1 hemoglobin subunit alpha 1 decreases expression ISO Sarin results in decreased expression of HBA1 protein CTD PMID:28973502 NCBI chr16:176,680...177,522
Ensembl chr16:176,680...177,522 		JBrowse link
G HDC histidine decarboxylase affects binding EXP Sarin binds to [HDC protein binds to Pyridoxal Phosphate]; Sarin binds to HDC protein CTD PMID:35151785 NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965 		JBrowse link
G HINT1 histidine triad nucleotide binding protein 1 decreases expression ISO Sarin results in decreased expression of HINT1 protein CTD PMID:28973502 NCBI chr 5:131,159,027...131,165,256
Ensembl chr 5:131,155,383...131,224,468 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 increases expression EXP Sarin results in increased expression of HIPK2 mRNA CTD PMID:19522546 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998 		JBrowse link
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Sarin results in decreased expression of HNRNPH1 protein CTD PMID:28973502 NCBI chr 5:179,614,178...179,634,784
Ensembl chr 5:179,614,178...179,634,784 		JBrowse link
G HP haptoglobin decreases expression ISO Sarin results in decreased expression of HP protein CTD PMID:26778279 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HPX hemopexin decreases expression ISO Sarin results in decreased expression of HPX protein CTD PMID:26778279 NCBI chr11:6,431,049...6,440,987
Ensembl chr11:6,431,049...6,442,617 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 decreases expression
increases expression		 EXP Sarin results in decreased expression of HSPA4 mRNA
Sarin results in increased expression of HSPA4 mRNA		 CTD PMID:19522546 NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Sarin results in decreased expression of HSPA8 protein CTD PMID:28973502 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPA9 heat shock protein family A (Hsp70) member 9 affects expression ISO Sarin affects the expression of HSPA9 protein CTD PMID:28973502 NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 affects expression ISO Sarin affects the expression of HSPD1 protein CTD PMID:28973502 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HTR1E 5-hydroxytryptamine receptor 1E decreases expression EXP Sarin results in decreased expression of HTR1E mRNA CTD PMID:19522546 NCBI chr 6:86,937,528...87,016,679
Ensembl chr 6:86,937,528...87,016,679 		JBrowse link
G IDS iduronate 2-sulfatase decreases expression EXP Sarin results in decreased expression of IDS mRNA CTD PMID:19522546 NCBI chr  X:149,476,988...149,505,306
Ensembl chr  X:149,476,988...149,521,096 		JBrowse link
G IFI16 interferon gamma inducible protein 16 increases expression EXP Sarin results in increased expression of IFI16 mRNA CTD PMID:19522546 NCBI chr 1:158,999,976...159,055,151
Ensembl chr 1:158,999,968...159,055,155 		JBrowse link
G IFNA7 interferon alpha 7 increases expression EXP Sarin results in increased expression of IFNA7 mRNA CTD PMID:19522546 NCBI chr 9:21,201,469...21,202,205
Ensembl chr 9:21,201,469...21,202,205 		JBrowse link
G IFRD1 interferon related developmental regulator 1 decreases expression EXP Sarin results in decreased expression of IFRD1 mRNA CTD PMID:19522546 NCBI chr 7:112,423,174...112,477,203
Ensembl chr 7:112,422,887...112,481,017 		JBrowse link
G IL17RC interleukin 17 receptor C increases expression EXP Sarin results in increased expression of IL17RC mRNA CTD PMID:19522546 NCBI chr 3:9,917,098...9,933,621
Ensembl chr 3:9,917,074...9,933,630 		JBrowse link
G IL1B interleukin 1 beta increases expression
multiple interactions		 ISO Sarin results in increased expression of IL1B mRNA; Sarin results in increased expression of IL1B protein
ezogabine inhibits the reaction [Sarin results in increased expression of IL1B protein]
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein		 CTD PMID:17301067 PMID:23692952 PMID:32209366 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL22RA1 interleukin 22 receptor subunit alpha 1 increases expression EXP Sarin results in increased expression of IL22RA1 mRNA CTD PMID:19522546 NCBI chr 1:24,119,771...24,143,140
Ensembl chr 1:24,119,771...24,143,140 		JBrowse link
G IL27RA interleukin 27 receptor subunit alpha increases expression EXP Sarin results in increased expression of IL27RA mRNA CTD PMID:19522546 NCBI chr19:14,031,762...14,053,218
Ensembl chr19:14,031,762...14,053,218 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 ISO Sarin results in increased expression of IL6 mRNA; Sarin results in increased expression of IL6 protein
ezogabine inhibits the reaction [Sarin results in increased expression of IL6 protein]		 CTD PMID:17301067 PMID:32209366 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G ILF2 interleukin enhancer binding factor 2 decreases expression
increases expression		 EXP Sarin results in decreased expression of ILF2 mRNA
Sarin results in increased expression of ILF2 mRNA		 CTD PMID:19522546 NCBI chr 1:153,661,788...153,670,993
Ensembl chr 1:153,661,788...153,671,028 		JBrowse link
G INA internexin neuronal intermediate filament protein alpha decreases expression ISO Sarin results in decreased expression of INA protein CTD PMID:28973502 NCBI chr10:103,277,138...103,290,346
Ensembl chr10:103,277,138...103,290,346 		JBrowse link
G INSIG1 insulin induced gene 1 increases expression
decreases expression		 EXP Sarin results in increased expression of INSIG1 mRNA
Sarin results in decreased expression of INSIG1 mRNA		 CTD PMID:19522546 NCBI chr 7:155,297,878...155,310,235
Ensembl chr 7:155,297,776...155,310,235 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 decreases expression EXP Sarin results in decreased expression of IQGAP1 mRNA CTD PMID:19522546 NCBI chr15:90,388,242...90,502,239
Ensembl chr15:90,388,242...90,502,239 		JBrowse link
G IRF2 interferon regulatory factor 2 decreases expression EXP Sarin results in decreased expression of IRF2 mRNA CTD PMID:19522546 NCBI chr 4:184,387,729...184,474,550
Ensembl chr 4:184,385,702...184,474,558 		JBrowse link
G ITM2B integral membrane protein 2B decreases expression EXP Sarin results in decreased expression of ITM2B mRNA CTD PMID:19522546 NCBI chr13:48,233,206...48,270,357
Ensembl chr13:48,232,612...48,270,357 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 decreases expression EXP Sarin results in decreased expression of ITPR1 mRNA CTD PMID:19522546 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G KAT5 lysine acetyltransferase 5 decreases expression EXP Sarin results in decreased expression of KAT5 mRNA CTD PMID:19522546 NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604 		JBrowse link
G KAT6B lysine acetyltransferase 6B decreases expression
increases expression		 EXP Sarin results in decreased expression of KAT6B mRNA
Sarin results in increased expression of KAT6B mRNA		 CTD PMID:19522546 NCBI chr10:74,824,936...75,032,624
Ensembl chr10:74,824,927...75,032,624 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 decreases expression
increases expression		 EXP Sarin results in decreased expression of KCNJ8 mRNA
Sarin results in increased expression of KCNJ8 mRNA		 CTD PMID:19522546 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G LAMP2 lysosomal associated membrane protein 2 decreases expression EXP Sarin results in decreased expression of LAMP2 mRNA CTD PMID:19522546 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365 		JBrowse link
G LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 decreases expression EXP Sarin results in decreased expression of LAMTOR2 mRNA CTD PMID:19522546 NCBI chr 1:156,054,782...156,058,506
Ensembl chr 1:156,054,782...156,058,506 		JBrowse link
G LASP1 LIM and SH3 protein 1 decreases expression ISO Sarin results in decreased expression of LASP1 protein CTD PMID:28973502 NCBI chr17:38,870,058...38,921,770
Ensembl chr17:38,869,859...38,921,770 		JBrowse link
G LIN7C lin-7 homolog C, crumbs cell polarity complex component increases expression EXP Sarin results in increased expression of LIN7C mRNA CTD PMID:19522546 NCBI chr11:27,494,418...27,506,769
Ensembl chr11:27,494,418...27,506,769 		JBrowse link
G LITAF lipopolysaccharide induced TNF factor decreases expression EXP Sarin results in decreased expression of LITAF mRNA CTD PMID:19522546 NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381 		JBrowse link
G LRP8 LDL receptor related protein 8 increases expression EXP Sarin results in increased expression of LRP8 mRNA CTD PMID:19522546 NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469 		JBrowse link
G MAP2 microtubule associated protein 2 decreases expression ISO Sarin results in decreased expression of MAP2 protein CTD PMID:27639427 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 decreases expression EXP Sarin results in decreased expression of MAP2K2 mRNA CTD PMID:19522546 NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122 		JBrowse link
G MAPT microtubule associated protein tau decreases expression EXP Sarin results in decreased expression of MAPT mRNA CTD PMID:19522546 NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334 		JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate decreases expression EXP Sarin results in decreased expression of MARCKS mRNA CTD PMID:19522546 NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475 		JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member decreases expression
increases expression		 EXP Sarin results in decreased expression of MCL1 mRNA
Sarin results in increased expression of MCL1 mRNA		 CTD PMID:19522546 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738 		JBrowse link
G MFAP4 microfibril associated protein 4 decreases expression
increases expression		 EXP Sarin results in decreased expression of MFAP4 mRNA
Sarin results in increased expression of MFAP4 mRNA		 CTD PMID:19522546 NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190 		JBrowse link
G MFN1 mitofusin 1 decreases expression EXP Sarin results in decreased expression of MFN1 mRNA CTD PMID:19522546 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MIF macrophage migration inhibitory factor increases expression ISO Sarin results in increased expression of MIF protein CTD PMID:28973502 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MPDU1 mannose-P-dolichol utilization defect 1 decreases expression EXP Sarin results in decreased expression of MPDU1 mRNA CTD PMID:19522546 NCBI chr17:7,583,647...7,588,212
Ensembl chr17:7,583,529...7,592,789 		JBrowse link
G MPZL1 myelin protein zero like 1 decreases expression EXP Sarin results in decreased expression of MPZL1 mRNA CTD PMID:19522546 NCBI chr 1:167,721,982...167,791,919
Ensembl chr 1:167,721,192...167,791,919 		JBrowse link
G MRPS28 mitochondrial ribosomal protein S28 decreases expression EXP Sarin results in decreased expression of MRPS28 mRNA CTD PMID:19522546 NCBI chr 8:79,918,717...80,030,259
Ensembl chr 8:79,918,717...80,030,289 		JBrowse link
G MTMR2 myotubularin related protein 2 decreases expression EXP Sarin results in decreased expression of MTMR2 mRNA CTD PMID:19522546 NCBI chr11:95,832,880...95,924,107
Ensembl chr11:95,821,766...95,925,315 		JBrowse link
G MUSK muscle associated receptor tyrosine kinase increases expression EXP Sarin results in increased expression of MUSK mRNA CTD PMID:19522546 NCBI chr 9:110,668,791...110,806,558
Ensembl chr 9:110,668,779...110,806,558 		JBrowse link
G NACA nascent polypeptide associated complex subunit alpha decreases expression EXP Sarin results in decreased expression of NACA mRNA CTD PMID:19522546 NCBI chr12:56,712,427...56,725,299
Ensembl chr12:56,712,305...56,731,628 		JBrowse link
G NAPG NSF attachment protein gamma decreases expression ISO Sarin results in decreased expression of NAPG protein CTD PMID:28973502 NCBI chr18:10,526,027...10,552,764
Ensembl chr18:10,525,905...10,552,764 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 decreases expression EXP Sarin results in decreased expression of NCOR1 mRNA CTD PMID:19522546 NCBI chr17:16,029,157...16,215,534
Ensembl chr17:16,029,065...16,218,185 		JBrowse link
G NDUFS4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression EXP Sarin results in decreased expression of NDUFS4 mRNA CTD PMID:19522546 NCBI chr 5:53,560,639...53,683,338
Ensembl chr 5:53,560,633...53,683,338 		JBrowse link
G NEFH neurofilament heavy chain increases phosphorylation ISO Sarin results in increased phosphorylation of NEFH protein CTD PMID:21439362 NCBI chr22:29,480,218...29,491,390
Ensembl chr22:29,480,218...29,491,390 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 affects localization ISO Sarin affects the localization of NFKB1 protein CTD PMID:17301067 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302 		JBrowse link
G NGRN neugrin, neurite outgrowth associated decreases expression EXP Sarin results in decreased expression of NGRN mRNA CTD PMID:19522546 NCBI chr15:90,265,663...90,272,211
Ensembl chr15:90,265,659...90,275,778 		JBrowse link
G NME1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression ISO Sarin results in decreased expression of NME1 protein CTD PMID:28973502 NCBI chr17:51,153,559...51,162,168
Ensembl chr17:51,153,559...51,162,428 		JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 affects expression ISO Sarin affects the expression of NME2 protein CTD PMID:28973502 NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744 		JBrowse link
G NMU neuromedin U decreases expression EXP Sarin results in decreased expression of NMU mRNA CTD PMID:19522546 NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698 		JBrowse link
G NOSIP nitric oxide synthase interacting protein increases expression EXP Sarin results in increased expression of NOSIP mRNA CTD PMID:19522546 NCBI chr19:49,555,468...49,580,556
Ensembl chr19:49,555,468...49,590,262 		JBrowse link
G NOTCH2 notch receptor 2 decreases expression EXP Sarin results in decreased expression of NOTCH2 mRNA CTD PMID:19522546 NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 decreases expression EXP Sarin results in decreased expression of NQO1 mRNA CTD PMID:19522546 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NQO2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 decreases expression EXP Sarin results in decreased expression of NQO2 mRNA CTD PMID:19522546 NCBI chr 6:2,999,894...3,019,755
Ensembl chr 6:2,987,987...3,019,755 		JBrowse link
G NRCAM neuronal cell adhesion molecule decreases expression EXP Sarin results in decreased expression of NRCAM mRNA CTD PMID:19522546 NCBI chr 7:108,147,649...108,456,720
Ensembl chr 7:108,147,623...108,456,717 		JBrowse link
G NRP1 neuropilin 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of NRP1 mRNA
Sarin results in increased expression of NRP1 mRNA		 CTD PMID:19522546 NCBI chr10:33,177,493...33,334,667
Ensembl chr10:33,177,492...33,336,262 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 increases expression EXP Sarin results in increased expression of NTRK2 mRNA CTD PMID:19522546 NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751 		JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 increases expression EXP Sarin results in increased expression of NTRK3 mRNA CTD PMID:19522546 NCBI chr15:87,859,751...88,256,739
Ensembl chr15:87,859,751...88,256,791 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of OLR1 mRNA
Sarin results in increased expression of OLR1 mRNA		 CTD PMID:19522546 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138 		JBrowse link
G OSMR oncostatin M receptor increases expression EXP Sarin results in increased expression of OSMR mRNA CTD PMID:19522546 NCBI chr 5:38,846,012...38,945,579
Ensembl chr 5:38,845,858...38,945,596 		JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta decreases expression EXP Sarin results in decreased expression of P4HB mRNA CTD PMID:19522546 NCBI chr17:81,843,166...81,860,535
Ensembl chr17:81,843,159...81,860,856 		JBrowse link
G PANK3 pantothenate kinase 3 decreases expression EXP Sarin results in decreased expression of PANK3 mRNA CTD PMID:19522546 NCBI chr 5:168,548,495...168,579,368
Ensembl chr 5:168,548,495...168,579,368 		JBrowse link
G PARK7 Parkinsonism associated deglycase decreases expression EXP
ISO		 Sarin results in decreased expression of PARK7 mRNA
Sarin results in decreased expression of PARK7 protein		 CTD PMID:19522546 PMID:28973502 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PARL presenilin associated rhomboid like decreases expression EXP Sarin results in decreased expression of PARL mRNA CTD PMID:19522546 NCBI chr 3:183,826,489...183,884,880
Ensembl chr 3:183,829,271...183,884,933 		JBrowse link
G PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase decreases expression EXP Sarin results in decreased expression of PCMT1 mRNA CTD PMID:19522546 NCBI chr 6:149,749,695...149,811,421
Ensembl chr 6:149,749,444...149,811,420 		JBrowse link
G PDHB pyruvate dehydrogenase E1 subunit beta decreases expression
increases expression		 EXP
ISO		 Sarin results in decreased expression of PDHB mRNA
Sarin results in decreased expression of PDHB protein
Sarin results in increased expression of PDHB mRNA		 CTD PMID:19522546 PMID:28973502 NCBI chr 3:58,427,630...58,433,832
Ensembl chr 3:58,427,630...58,433,857 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 affects expression ISO Sarin affects the expression of PDIA3 protein CTD PMID:28973502 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase decreases expression EXP Sarin results in decreased expression of PEMT mRNA CTD PMID:19522546 NCBI chr17:17,505,563...17,592,142
Ensembl chr17:17,505,563...17,591,708 		JBrowse link
G PEPD peptidase D increases hydrolysis EXP PEPD protein results in increased hydrolysis of Sarin CTD PMID:20176006 PMID:22120822 PMID:22677456 NCBI chr19:33,386,950...33,521,791
Ensembl chr19:33,386,950...33,521,823 		JBrowse link
G PFKP phosphofructokinase, platelet decreases expression EXP Sarin results in decreased expression of PFKP mRNA CTD PMID:19522546 NCBI chr10:3,067,548...3,136,805
Ensembl chr10:3,066,333...3,137,718 		JBrowse link
G PFN2 profilin 2 decreases expression ISO Sarin results in decreased expression of PFN2 protein CTD PMID:28973502 NCBI chr 3:149,964,904...149,970,895
Ensembl chr 3:149,964,904...150,050,788 		JBrowse link
G PLA2G5 phospholipase A2 group V decreases expression
increases expression		 EXP Sarin results in decreased expression of PLA2G5 mRNA
Sarin results in increased expression of PLA2G5 mRNA		 CTD PMID:19522546 NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911 		JBrowse link
G PLA2G6 phospholipase A2 group VI increases expression EXP Sarin results in increased expression of PLA2G6 mRNA CTD PMID:19522546 NCBI chr22:38,111,495...38,181,830
Ensembl chr22:38,111,495...38,214,778 		JBrowse link
G PLAA phospholipase A2 activating protein increases expression EXP Sarin results in increased expression of PLAA mRNA CTD PMID:19522546 NCBI chr 9:26,903,372...26,947,242
Ensembl chr 9:26,903,372...26,947,242 		JBrowse link
G PLTP phospholipid transfer protein decreases expression EXP Sarin results in decreased expression of PLTP mRNA CTD PMID:19522546 NCBI chr20:45,898,620...45,912,155
Ensembl chr20:45,898,621...45,912,155 		JBrowse link
G PMP22 peripheral myelin protein 22 decreases expression EXP Sarin results in decreased expression of PMP22 mRNA CTD PMID:19522546 NCBI chr17:15,229,779...15,265,326
Ensembl chr17:15,229,773...15,272,292 		JBrowse link
G PNMA1 PNMA family member 1 decreases expression
increases expression		 EXP Sarin results in decreased expression of PNMA1 mRNA
Sarin results in increased expression of PNMA1 mRNA		 CTD PMID:19522546 NCBI chr14:73,711,783...73,714,384
Ensembl chr14:73,711,783...73,714,384 		JBrowse link
G PNPLA6 patatin like phospholipase domain containing 6 decreases activity ISO Sarin results in decreased activity of PNPLA6 protein CTD PMID:8486913 NCBI chr19:7,534,164...7,561,767
Ensembl chr19:7,534,004...7,561,764 		JBrowse link
G POMC proopiomelanocortin decreases expression ISO Sarin results in decreased expression of POMC protein CTD PMID:17301067 NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PON1 paraoxonase 1 multiple interactions
increases hydrolysis
decreases response to substance		 EXP PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]
PON1 protein mutant form results in increased hydrolysis of Sarin; PON1 protein results in increased hydrolysis of Sarin
PON1 protein mutant form results in decreased susceptibility to Sarin		 CTD PMID:16331452 PMID:20176006 PMID:21329748 PMID:23159884 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G POR cytochrome p450 oxidoreductase decreases expression
increases expression		 EXP Sarin results in decreased expression of POR mRNA
Sarin results in increased expression of POR mRNA		 CTD PMID:19522546 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha decreases expression EXP Sarin results in decreased expression of PPP1CA mRNA CTD PMID:19522546 NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183 		JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 decreases expression EXP Sarin results in decreased expression of PPT1 mRNA CTD PMID:19522546 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260 		JBrowse link
G PRDX6 peroxiredoxin 6 decreases expression ISO Sarin results in decreased expression of PRDX6 protein CTD PMID:28973502 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815 		JBrowse link
G PRKCB protein kinase C beta increases expression EXP Sarin results in increased expression of PRKCB mRNA CTD PMID:19522546 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRSS12 serine protease 12 decreases expression EXP Sarin results in decreased expression of PRSS12 mRNA CTD PMID:19522546 NCBI chr 4:118,280,038...118,353,003
Ensembl chr 4:118,280,038...118,353,003 		JBrowse link
G PSEN1 presenilin 1 decreases expression EXP Sarin results in decreased expression of PSEN1 mRNA; Sarin results in decreased expression of PSEN1 protein CTD PMID:19522546 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G PSEN2 presenilin 2 decreases expression EXP Sarin results in decreased expression of PSEN2 mRNA CTD PMID:19522546 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G PSMA1 proteasome 20S subunit alpha 1 increases expression ISO Sarin results in increased expression of PSMA1 protein CTD PMID:28973502 NCBI chr11:14,504,876...14,643,662
Ensembl chr11:14,504,874...14,643,635 		JBrowse link
G PSMA3 proteasome 20S subunit alpha 3 decreases expression
increases expression		 EXP Sarin results in decreased expression of PSMA3 mRNA
Sarin results in increased expression of PSMA3 mRNA		 CTD PMID:19522546 NCBI chr14:58,244,843...58,272,004
Ensembl chr14:58,244,843...58,272,012 		JBrowse link
G PSMD8 proteasome 26S subunit, non-ATPase 8 decreases expression EXP Sarin results in decreased expression of PSMD8 mRNA CTD PMID:19522546 NCBI chr19:38,374,571...38,383,824
Ensembl chr19:38,374,563...38,383,850 		JBrowse link
G PTPRR protein tyrosine phosphatase receptor type R decreases expression EXP Sarin results in decreased expression of PTPRR mRNA CTD PMID:19522546 NCBI chr12:70,638,073...70,920,738
Ensembl chr12:70,638,073...70,920,738 		JBrowse link
G PTS 6-pyruvoyltetrahydropterin synthase decreases expression EXP Sarin results in decreased expression of PTS mRNA CTD PMID:19522546 NCBI chr11:112,226,428...112,233,973
Ensembl chr11:112,226,367...112,269,955 		JBrowse link
G PURA purine rich element binding protein A affects expression ISO Sarin affects the expression of PURA protein CTD PMID:28973502 NCBI chr 5:140,114,109...140,125,619
Ensembl chr 5:140,107,777...140,125,619 		JBrowse link
G PZP PZP alpha-2-macroglobulin like increases expression ISO Sarin results in increased expression of PZP protein CTD PMID:26778279 NCBI chr12:9,136,472...9,208,395
Ensembl chr12:9,148,840...9,208,395 		JBrowse link
G RANBP1 RAN binding protein 1 decreases expression EXP Sarin results in decreased expression of RANBP1 mRNA CTD PMID:19522546 NCBI chr22:20,116,104...20,127,355
Ensembl chr22:20,115,938...20,127,355 		JBrowse link
G RASGRP2 RAS guanyl releasing protein 2 increases expression EXP Sarin results in increased expression of RASGRP2 mRNA CTD PMID:19522546 NCBI chr11:64,726,911...64,745,456
Ensembl chr11:64,726,911...64,745,456 		JBrowse link
G RFXANK regulatory factor X associated ankyrin containing protein decreases expression EXP Sarin results in decreased expression of RFXANK mRNA CTD PMID:19522546 NCBI chr19:19,192,258...19,201,866
Ensembl chr19:19,192,229...19,201,869 		JBrowse link
G RGN regucalcin increases hydrolysis ISO RGN protein results in increased hydrolysis of Sarin CTD PMID:20176006 NCBI chr  X:47,078,443...47,093,313
Ensembl chr  X:47,078,355...47,093,314 		JBrowse link
G RGS4 regulator of G protein signaling 4 decreases expression EXP Sarin results in decreased expression of RGS4 mRNA CTD PMID:19522546 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RTN3 reticulon 3 decreases expression EXP Sarin results in decreased expression of RTN3 mRNA CTD PMID:19522546 NCBI chr11:63,681,450...63,759,891
Ensembl chr11:63,681,446...63,759,891 		JBrowse link
G SCARB2 scavenger receptor class B member 2 decreases expression EXP Sarin results in decreased expression of SCARB2 mRNA CTD PMID:19522546 NCBI chr 4:76,158,737...76,234,532
Ensembl chr 4:76,158,737...76,234,536 		JBrowse link
G SCD stearoyl-CoA desaturase decreases expression
increases expression		 EXP Sarin results in decreased expression of SCD mRNA
Sarin results in increased expression of SCD mRNA		 CTD PMID:19522546 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 increases expression EXP Sarin results in increased expression of SCN10A mRNA CTD PMID:19522546 NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286 		JBrowse link
G SDCBP syndecan binding protein decreases expression EXP Sarin results in decreased expression of SDCBP mRNA CTD PMID:19522546 NCBI chr 8:58,553,261...58,582,858
Ensembl chr 8:58,552,924...58,582,859 		JBrowse link
G SEPTIN5 septin 5 increases expression ISO Sarin results in increased expression of SEPTIN5 protein CTD PMID:28973502 NCBI chr22:19,714,503...19,723,319
Ensembl chr22:19,714,503...19,724,224 		JBrowse link
G SERPINI1 serpin family I member 1 decreases expression EXP Sarin results in decreased expression of SERPINI1 mRNA CTD PMID:19522546 NCBI chr 3:167,735,721...167,825,569
Ensembl chr 3:167,735,243...167,825,569 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 decreases expression EXP Sarin results in decreased expression of SGK1 mRNA CTD PMID:19522546 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SH3GL1 SH3 domain containing GRB2 like 1, endophilin A2 decreases expression ISO Sarin results in decreased expression of SH3GL1 protein CTD PMID:28973502 NCBI chr19:4,360,370...4,400,547
Ensembl chr19:4,360,370...4,400,547 		JBrowse link
G SLC18A3 solute carrier family 18 member A3 decreases expression ISO Sarin results in decreased expression of SLC18A3 protein CTD PMID:22640809 NCBI chr10:49,610,310...49,612,720
Ensembl chr10:49,610,310...49,612,720 		JBrowse link
G SLC20A1 solute carrier family 20 member 1 decreases expression EXP Sarin results in decreased expression of SLC20A1 mRNA CTD PMID:19522546 NCBI chr 2:112,645,939...112,663,825
Ensembl chr 2:112,645,939...112,663,825 		JBrowse link
G SLC6A15 solute carrier family 6 member 15 decreases expression EXP Sarin results in decreased expression of SLC6A15 mRNA CTD PMID:19522546 NCBI chr12:84,859,491...84,912,799
Ensembl chr12:84,859,491...84,913,629 		JBrowse link
G SNCA synuclein alpha decreases expression EXP
ISO		 Sarin results in decreased expression of SNCA mRNA
Sarin results in decreased expression of SNCA protein		 CTD PMID:19522546 PMID:28973502 NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 decreases expression
increases expression		 EXP Sarin results in decreased expression of SOCS5 mRNA
Sarin results in increased expression of SOCS5 mRNA		 CTD PMID:19522546 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245 		JBrowse link
G SOD1 superoxide dismutase 1 decreases expression ISO Sarin results in decreased expression of SOD1 protein CTD PMID:28973502 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SPAST spastin decreases expression EXP Sarin results in decreased expression of SPG4 mRNA CTD PMID:19522546 NCBI chr 2:32,063,556...32,157,637
Ensembl chr 2:32,063,556...32,157,637 		JBrowse link
G STIP1 stress induced phosphoprotein 1 affects expression ISO Sarin affects the expression of STIP1 protein CTD PMID:28973502 NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,543 		JBrowse link
G STMN1 stathmin 1 decreases expression ISO Sarin results in decreased expression of STMN1 protein CTD PMID:28973502 NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991 		JBrowse link
G STMN2 stathmin 2 decreases expression EXP Sarin results in decreased expression of STMN2 mRNA CTD PMID:19522546 NCBI chr 8:79,611,117...79,666,158
Ensembl chr 8:79,611,117...79,666,158 		JBrowse link
G STX4 syntaxin 4 decreases expression EXP Sarin results in decreased expression of STX4A mRNA CTD PMID:19522546 NCBI chr16:31,033,095...31,040,168
Ensembl chr16:31,032,889...31,042,975 		JBrowse link
G SYT1 synaptotagmin 1 increases expression EXP Sarin results in increased expression of SYT1 mRNA CTD PMID:19522546 NCBI chr12:78,863,982...79,452,008
Ensembl chr12:78,863,993...79,452,008 		JBrowse link
G TAGLN3 transgelin 3 increases expression ISO Sarin results in increased expression of TAGLN3 protein CTD PMID:28973502 NCBI chr 3:111,998,922...112,013,885
Ensembl chr 3:111,998,739...112,013,887 		JBrowse link
G TBCC tubulin folding cofactor C decreases expression
increases expression		 EXP Sarin results in decreased expression of TBCC mRNA
Sarin results in increased expression of TBCC mRNA		 CTD PMID:19522546 NCBI chr 6:42,744,498...42,746,103
Ensembl chr 6:42,744,498...42,746,103 		JBrowse link
G TCFL5 transcription factor like 5 decreases expression EXP Sarin results in decreased expression of TCFL5 mRNA CTD PMID:19522546 NCBI chr20:62,841,005...62,861,822
Ensembl chr20:62,841,005...62,861,822 		JBrowse link
G TF transferrin affects binding EXP
ISO		 Sarin binds to TF protein
Sarin binds to TRF protein		 CTD PMID:18930948 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G TFRC transferrin receptor decreases expression EXP Sarin results in decreased expression of TFRC mRNA CTD PMID:19522546 NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153 		JBrowse link
G TM2D1 TM2 domain containing 1 increases expression EXP Sarin results in increased expression of TM2D1 mRNA CTD PMID:19522546 NCBI chr 1:61,681,046...61,725,141
Ensembl chr 1:61,681,046...61,725,423 		JBrowse link
G TMED10 transmembrane p24 trafficking protein 10 decreases expression EXP Sarin results in decreased expression of TMED10 mRNA CTD PMID:19522546 NCBI chr14:75,131,469...75,176,612
Ensembl chr14:75,131,469...75,176,612 		JBrowse link
G TMSB15A thymosin beta 15A decreases expression EXP Sarin results in decreased expression of TMSB15A mRNA CTD PMID:19522546 NCBI chr  X:102,513,682...102,516,739
Ensembl chr  X:102,513,682...102,516,739 		JBrowse link
G TNF tumor necrosis factor increases expression ISO Sarin results in increased expression of TNF mRNA CTD PMID:17301067 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF6B TNF receptor superfamily member 6b increases expression EXP Sarin results in increased expression of TNFRSF6B mRNA CTD PMID:19522546 NCBI chr20:63,696,652...63,698,684
Ensembl chr20:63,696,652...63,698,684 		JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 increases expression EXP Sarin results in increased expression of TNFRSF9 mRNA CTD PMID:19522546 NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165 		JBrowse link
G TOP2A DNA topoisomerase II alpha decreases expression EXP Sarin results in decreased expression of TOP2A mRNA CTD PMID:19522546 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TPI1 triosephosphate isomerase 1 affects expression ISO Sarin affects the expression of TPI1 protein CTD PMID:28973502 NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948 		JBrowse link
G TPM1 tropomyosin 1 decreases expression EXP Sarin results in decreased expression of TPM1 mRNA CTD PMID:19522546 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TRAF5 TNF receptor associated factor 5 increases expression EXP Sarin results in increased expression of TRAF5 mRNA CTD PMID:19522546 NCBI chr 1:211,326,635...211,374,946
Ensembl chr 1:211,326,615...211,374,946 		JBrowse link
G TRPM3 transient receptor potential cation channel subfamily M member 3 increases expression EXP Sarin results in increased expression of TRPM3 mRNA CTD PMID:19522546 NCBI chr 9:70,529,060...71,446,971
Ensembl chr 9:70,529,060...71,446,904 		JBrowse link
G TSPAN3 tetraspanin 3 decreases expression EXP Sarin results in decreased expression of TSPAN3 mRNA CTD PMID:19522546 NCBI chr15:77,041,404...77,071,109
Ensembl chr15:77,041,404...77,083,984 		JBrowse link
G TSPO translocator protein increases expression
multiple interactions		 ISO Sarin results in increased expression of TSPO mRNA; Sarin results in increased expression of TSPO protein
[Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]; [Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein; ezogabine inhibits the reaction [Sarin results in increased expression of TSPO protein]		 CTD PMID:27639427 PMID:32209366 PMID:33823148 NCBI chr22:43,151,559...43,163,242
Ensembl chr22:43,151,547...43,163,242 		JBrowse link
G TUBB2B tubulin beta 2B class IIb decreases expression ISO Sarin results in decreased expression of TUBB2B protein CTD PMID:28973502 NCBI chr 6:3,224,277...3,227,653
Ensembl chr 6:3,223,324...3,231,730 		JBrowse link
G TUBB3 tubulin beta 3 class III decreases expression ISO Sarin results in decreased expression of TUBB3 protein CTD PMID:28973502 NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761 		JBrowse link
G TUBG1 tubulin gamma 1 decreases expression EXP Sarin results in decreased expression of TUBG1 mRNA CTD PMID:19522546 NCBI chr17:42,609,683...42,615,238
Ensembl chr17:42,609,641...42,615,238 		JBrowse link
G UBE2G1 ubiquitin conjugating enzyme E2 G1 decreases expression EXP Sarin results in decreased expression of UBE2G1 mRNA CTD PMID:19522546 NCBI chr17:4,269,259...4,366,675
Ensembl chr17:4,269,259...4,366,675 		JBrowse link
G UBE2M ubiquitin conjugating enzyme E2 M decreases expression EXP Sarin results in decreased expression of UBE2M mRNA CTD PMID:19522546 NCBI chr19:58,555,712...58,558,611
Ensembl chr19:58,555,712...58,558,954 		JBrowse link
G UCHL1 ubiquitin C-terminal hydrolase L1 affects expression ISO Sarin affects the expression of UCHL1 protein CTD PMID:28973502 NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455 		JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 decreases expression EXP Sarin results in decreased expression of UCHL3 mRNA CTD PMID:19522546 NCBI chr13:75,549,502...75,606,020
Ensembl chr13:75,549,483...75,606,020 		JBrowse link
G USP14 ubiquitin specific peptidase 14 decreases expression EXP Sarin results in decreased expression of USP14 mRNA CTD PMID:19522546 NCBI chr18:158,557...214,629
Ensembl chr18:158,383...214,629 		JBrowse link
G VAMP3 vesicle associated membrane protein 3 decreases expression EXP Sarin results in decreased expression of VAMP3 mRNA CTD PMID:19522546 NCBI chr 1:7,771,296...7,781,432
Ensembl chr 1:7,771,296...7,781,432 		JBrowse link
G VDAC1 voltage dependent anion channel 1 increases expression EXP Sarin results in increased expression of VDAC1 mRNA CTD PMID:19522546 NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975 		JBrowse link
G YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta decreases expression
increases expression		 EXP Sarin results in decreased expression of YWHAB mRNA
Sarin results in increased expression of YWHAB mRNA		 CTD PMID:19522546 NCBI chr20:44,885,705...44,908,532
Ensembl chr20:44,885,702...44,908,532 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon decreases expression EXP Sarin results in decreased expression of YWHAE mRNA CTD PMID:19522546 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222 		JBrowse link
G ZEB1 zinc finger E-box binding homeobox 1 decreases expression EXP Sarin results in decreased expression of ZEB1 mRNA CTD PMID:19522546 NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814 		JBrowse link
G ZNF532 zinc finger protein 532 decreases expression EXP Sarin results in decreased expression of ZNF532 mRNA CTD PMID:19522546 NCBI chr18:58,862,924...58,986,480
Ensembl chr18:58,862,600...58,986,480 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    role 25957
      biological role 25936
        aetiopathogenetic role 24601
          neurotoxin 20825
            sarin 296
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            heteroorganic entity 24773
                              organochalcogen compound 24384
                                organooxygen compound 24061
                                  ester 18758
                                    phosphinic ester 324
                                      isopropyl methylphosphonofluoridate 296
                                        (S)-sarin 296
                                          sarin 296
paths to the root