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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(S)-sarin
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Accession:CHEBI:75871 term browser browse the term
Definition:The (S)-enantiomer of sarin; the more potent enantiomer of racemic sarin, a nerve agent that is employed as a chemical warfare agent.
Synonyms:exact_synonym: isopropyl (S)-methylphosphonofluoridate
 related_synonym: Formula=C4H10FO2P;   InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3/t8-/m0/s1;   InChIKey=DYAHQFWOVKZOOW-QMMMGPOBSA-N;   SMILES=CC(C)O[P@@](C)(F)=O;   sarin
 xref: CAS:6171-94-4;   Reaxys:2409983;   Wikipedia:Sarin
 cyclic_relationship: is_enantiomer_of CHEBI:75872


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sarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO Sarin results in decreased expression of ABCB1 mRNA CTD PMID:19522546 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression ISO Sarin results in decreased expression of ABCD3 mRNA CTD PMID:19522546 NCBI chr 2:225,335,708...225,389,120
Ensembl chr 2:225,335,718...225,389,120
JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 decreases expression
increases expression
ISO Sarin results in decreased expression of ABCF2 mRNA
Sarin results in increased expression of ABCF2 mRNA
CTD PMID:19522546 NCBI chr 4:7,122,850...7,135,607
Ensembl chr 4:7,122,890...7,135,669
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression ISO Sarin results in decreased expression of ACAA2 mRNA CTD PMID:19522546 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression
increases expression
ISO Sarin results in decreased expression of ACAT2 mRNA
Sarin results in increased expression of ACAT2 mRNA
CTD PMID:19522546 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Ache acetylcholinesterase increases metabolic processing
affects expression
decreases activity
multiple interactions
increases phosphorylation
decreases expression
increases activity
ISO
EXP
Sarin results in increased metabolism of ACHE protein; Sarin results in increased metabolism of ACHE protein mutant form
Sarin affects the expression of ACHE mRNA
Sarin analog results in decreased activity of ACHE protein; Sarin metabolite results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein
1-((4-(aminocarbonyl)pyridinio)trimethylene)-2-((hydroxyimino)methyl)pyridinium inhibits the reaction [Sarin results in decreased activity of ACHE protein]; 4-amino-2-((diethylamino)methyl)phenol analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with asoxime chloride] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride affects the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; benzohydroxamic acid analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Donepezil promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; HLo 7 affects the reaction [Sarin results in decreased activity of ACHE protein]; Imipramine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Imipramine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; isonitrosoacetone inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; isonitrosoacetone inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-p-xylene-bis-((2,2'-hydroxyiminomethyl)pyridinium) dibromide inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pralidoxime Compounds inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pyridine-4-aldoxime analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; RS194B analog inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS41A inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Sarin binds to and results in decreased activity of ACHE protein
Sarin results in increased phosphorylation of ACHE protein
Sarin analog results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein
asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; BI 6 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N(6)-cyclopentyladenosine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Physostigmine affects the reaction [Sarin affects the expression of ACHE mRNA]; Physostigmine affects the reaction [Sarin affects the expression of and affects the activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pyridinium Compounds inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Sarin affects the expression of and affects the activity of ACHE protein; Trimedoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in decreased activity of ACHE protein; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Sarin binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein
Sarin results in decreased expression of ACHE mRNA
Sarin results in increased activity of ACHE protein
CTD PMID:1609424, PMID:12415428, PMID:14631503, PMID:16025528, PMID:17370251, PMID:17402711, PMID:17503400, PMID:18579126, PMID:18617161, PMID:19283689, PMID:19429253, PMID:19522546, PMID:19715346, PMID:20105433, PMID:20156428, PMID:20433814, PMID:20510297, PMID:20669006, PMID:20688148, PMID:20888357, PMID:21329748, PMID:21439362, PMID:21504785, PMID:21803135, PMID:21930118, PMID:22230262, PMID:22247004, PMID:22407886, PMID:22640809, PMID:22975155, PMID:22982773, PMID:23073172, PMID:23123249, PMID:23692952, PMID:25451328, PMID:25522658, PMID:25743373, PMID:26070418, PMID:27129421, PMID:27138243, PMID:27153754, PMID:28693885, PMID:28973502, PMID:29920286, PMID:30312685, PMID:30763608, PMID:31794810, PMID:31863869 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acly ATP citrate lyase decreases expression ISO Sarin results in decreased expression of ACLY mRNA CTD PMID:19522546 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Add1 adducin 1 decreases expression ISO Sarin results in decreased expression of ADD1 mRNA CTD PMID:19522546 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adora1 adenosine A1 receptor increases expression ISO Sarin results in increased expression of ADORA1 mRNA CTD PMID:19522546 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Sarin results in decreased expression of ADORA2A mRNA CTD PMID:19522546 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Agrn agrin decreases expression ISO Sarin results in decreased expression of AGRN mRNA CTD PMID:19522546 NCBI chr 5:173,589,910...173,622,813
Ensembl chr 5:173,589,819...173,622,645
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression ISO Sarin results in decreased expression of AHCY mRNA CTD PMID:19522546 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Sarin results in decreased expression of AK1 protein CTD PMID:28973502 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Sarin results in decreased expression of AK3 mRNA CTD PMID:19522546 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression
increases expression
ISO Sarin results in decreased expression of AKAP9 mRNA
Sarin results in increased expression of AKAP9 mRNA
CTD PMID:19522546 NCBI chr 4:27,195,346...27,331,582
Ensembl chr 4:27,195,346...27,331,582
JBrowse link
G Alb albumin affects binding
increases expression
ISO
EXP
Sarin binds to ALB protein
Sarin results in increased expression of ALB protein
CTD PMID:17188226, PMID:28973502 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO Sarin results in decreased expression of ALDOA mRNA CTD PMID:19522546 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C affects expression EXP Sarin affects the expression of ALDOC protein CTD PMID:28973502 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Sarin results in decreased expression of AMACR mRNA CTD PMID:19522546 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression ISO Sarin results in increased expression of APBB3 mRNA CTD PMID:19522546 NCBI chr18:29,497,865...29,504,995
Ensembl chr18:29,497,863...29,504,995
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 increases expression ISO Sarin results in increased expression of APLP1 mRNA CTD PMID:19522546 NCBI chr 1:88,897,525...88,908,750
Ensembl chr 1:88,897,532...88,908,750
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP Sarin results in decreased expression of APOA1 protein CTD PMID:26778279 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoc4 apolipoprotein C4 increases expression ISO Sarin results in increased expression of APOC4 mRNA CTD PMID:19522546 NCBI chr 1:80,595,339...80,599,525
Ensembl chr 1:80,595,326...80,599,572
JBrowse link
G Apoe apolipoprotein E increases expression ISO Sarin results in increased expression of APOE mRNA; Sarin results in increased expression of APOE protein CTD PMID:19522546 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein decreases expression ISO Sarin results in decreased expression of APP mRNA CTD PMID:19522546 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP Sarin results in increased expression of ARPC5L protein CTD PMID:28973502 NCBI chr 3:23,301,455...23,309,077
Ensembl chr 3:23,301,455...23,309,072
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 decreases expression
increases expression
ISO Sarin results in decreased expression of ASCL1 mRNA
Sarin results in increased expression of ASCL1 mRNA
CTD PMID:19522546 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Asl argininosuccinate lyase decreases expression ISO Sarin results in decreased expression of ASL mRNA CTD PMID:19522546 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO Sarin results in decreased expression of ATP1B1 mRNA CTD PMID:19522546 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression EXP Sarin results in decreased expression of ATP5H protein CTD PMID:28973502 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Sarin results in decreased expression of ATP5PO mRNA CTD PMID:19522546 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 decreases expression ISO Sarin results in decreased expression of ATP6V0A2 mRNA CTD PMID:19522546 NCBI chr12:37,368,321...37,398,233
Ensembl chr12:37,363,906...37,425,596
JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 decreases expression ISO Sarin results in decreased expression of ATP6V0E mRNA CTD PMID:19522546 NCBI chr10:16,769,857...16,792,930
Ensembl chr10:16,769,666...16,792,909
JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) increases expression ISO Sarin results in increased expression of ATP9B mRNA CTD PMID:19522546 NCBI chr18:77,343,551...77,535,608
Ensembl chr18:77,343,551...77,535,593
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO Sarin results in decreased expression of B2M mRNA CTD PMID:19522546 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression
increases expression
ISO Sarin results in decreased expression of BAG1 mRNA
Sarin results in increased expression of BAG1 mRNA
CTD PMID:19522546 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
ISO
EXP
Sarin results in increased expression of BAX mRNA
Sarin affects the expression of BAX mRNA; Sarin affects the expression of BAX protein
CTD PMID:19522546, PMID:27639427 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
decreases response to substance
increases phosphorylation
decreases expression
affects binding
ISO
EXP
asoxime chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of BCHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sarin analog promotes the reaction [Sarin binds to BCHE protein]
Physostigmine inhibits the reaction [Sarin results in decreased activity of BCHE protein]
BCHE protein results in decreased susceptibility to Sarin
Sarin results in increased phosphorylation of BCHE protein
Sarin results in decreased expression of BCHE mRNA
Sarin analog results in decreased activity of BCHE protein; Sarin metabolite results in decreased activity of BCHE protein; Sarin results in decreased activity of BCHE protein
CTD PMID:17698511, PMID:18617161, PMID:19283689, PMID:19428953, PMID:19522546, PMID:19715346, PMID:19715348, PMID:21329748, PMID:21802514, PMID:22247004, PMID:22407886, PMID:26145887, PMID:26778279, PMID:29920286, PMID:30763608, PMID:31863869 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
EXP Sarin results in increased expression of BCL2 mRNA
Sarin results in decreased expression of BCL2 protein
CTD PMID:27639427 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression
ISO Sarin results in decreased expression of BCL2L1 mRNA
Sarin results in increased expression of BCL2L1 mRNA
CTD PMID:19522546 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bex3 brain expressed X-linked 3 decreases expression ISO Sarin results in decreased expression of BEX3 mRNA CTD PMID:19522546 NCBI chr  X:106,823,442...106,825,016
Ensembl chr  X:106,823,491...106,825,014
JBrowse link
G Bptf bromodomain PHD finger transcription factor increases expression ISO Sarin results in increased expression of BPTF mRNA CTD PMID:19522546 NCBI chr10:95,248,573...95,350,162
Ensembl chr10:95,250,294...95,349,789
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 decreases expression
increases expression
ISO Sarin results in decreased expression of CACNG4 mRNA
Sarin results in increased expression of CACNG4 mRNA
CTD PMID:19522546 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Calm1 calmodulin 1 increases expression
decreases expression
ISO Sarin results in increased expression of CALM1 mRNA
Sarin results in decreased expression of CALM1 mRNA
CTD PMID:19522546 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Sarin results in decreased expression of CALM3 mRNA CTD PMID:19522546 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Capn1 calpain 1 increases expression EXP Sarin results in increased expression of CAPN1 protein CTD PMID:21439362 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Casp4 caspase 4 increases expression ISO Sarin results in increased expression of CASP4 mRNA CTD PMID:19522546 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO Sarin results in increased expression of CCR1 mRNA CTD PMID:19522546 NCBI chr 8:132,996,646...133,002,201
Ensembl chr 8:132,996,649...133,002,201
JBrowse link
G Cd24 CD24 molecule decreases expression
increases expression
ISO Sarin results in decreased expression of CD24 mRNA
Sarin results in increased expression of CD24 mRNA
CTD PMID:19522546 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd9 CD9 molecule decreases expression ISO Sarin results in decreased expression of CD9 mRNA; Sarin results in decreased expression of CD9 protein CTD PMID:19522546 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression
increases expression
ISO Sarin results in decreased expression of CDK5 mRNA
Sarin results in increased expression of CDK5 mRNA
CTD PMID:19522546 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 increases expression ISO Sarin results in increased expression of CEPT1 mRNA CTD PMID:19522546 NCBI chr 2:209,118,140...209,162,071
Ensembl chr 2:209,118,922...209,160,653
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO CES1 protein affects the metabolism of and results in decreased activity of Sarin CTD PMID:12679808 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Sarin results in increased expression of CFLAR mRNA CTD PMID:19522546 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP Sarin results in decreased expression of CHAT protein CTD PMID:22640809 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects activity
decreases expression
multiple interactions
EXP Sarin affects the activity of CHRM2 protein
Sarin results in decreased expression of CHRM2 protein
Sarin inhibits the reaction [AFDX 384 binds to CHRM2 protein]
CTD PMID:21419149, PMID:29128314 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit decreases expression ISO Sarin results in decreased expression of CHRNA3 mRNA CTD PMID:19522546 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit decreases expression ISO Sarin results in decreased expression of CHRNB1 mRNA CTD PMID:19522546 NCBI chr10:56,390,671...56,403,255
Ensembl chr10:56,390,671...56,403,188
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Sarin results in decreased expression of CHRNB4 mRNA CTD PMID:19522546 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression ISO Sarin results in increased expression of CHRNE mRNA CTD PMID:19522546 NCBI chr10:57,238,960...57,246,750
Ensembl chr10:57,238,946...57,243,435
JBrowse link
G Cklf chemokine-like factor decreases expression
increases expression
ISO Sarin results in decreased expression of CKLF mRNA
Sarin results in increased expression of CKLF mRNA
CTD PMID:19522546 NCBI chr19:903,609...914,880
Ensembl chr19:906,411...914,880
JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Sarin results in decreased expression of CLCN3 mRNA CTD PMID:19522546 NCBI chr16:32,448,821...32,520,649
Ensembl chr16:32,449,116...32,519,148
JBrowse link
G Clns1a chloride nucleotide-sensitive channel 1A decreases expression ISO Sarin results in decreased expression of CLNS1A mRNA CTD PMID:19522546 NCBI chr 1:162,676,246...162,696,549
Ensembl chr 1:162,676,269...162,696,544
JBrowse link
G Clu clusterin decreases expression ISO Sarin results in decreased expression of CLU mRNA CTD PMID:19522546 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Sarin results in increased expression of CNR2 mRNA CTD PMID:19522546 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Sarin results in decreased expression of COL3A1 mRNA CTD PMID:19522546 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Coro1a coronin 1A decreases expression EXP Sarin results in decreased expression of CORO1A protein CTD PMID:28973502 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 decreases expression
increases expression
ISO Sarin results in decreased expression of COX15 mRNA
Sarin results in increased expression of COX15 mRNA
CTD PMID:19522546 NCBI chr 1:263,494,850...263,511,510
Ensembl chr 1:263,494,852...263,511,505
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression EXP Sarin results in decreased expression of COX5A protein CTD PMID:28973502 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression EXP Sarin results in decreased expression of COX5B protein CTD PMID:28973502 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 decreases expression
increases expression
ISO
EXP
Sarin results in decreased expression of COX6A1 mRNA
Sarin results in increased expression of COX6A1 protein
CTD PMID:19522546, PMID:28973502 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cplx2 complexin 2 decreases expression EXP Sarin results in decreased expression of CPLX2 protein CTD PMID:28973502 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Creb3 cAMP responsive element binding protein 3 decreases expression ISO Sarin results in decreased expression of CREB3 mRNA CTD PMID:19522546 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188
JBrowse link
G Cst3 cystatin C decreases expression ISO Sarin results in decreased expression of CST3 mRNA CTD PMID:19522546 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Cstb cystatin B decreases expression
increases expression
ISO Sarin results in decreased expression of CSTB mRNA
Sarin results in increased expression of CSTB mRNA
CTD PMID:19522546 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctsd cathepsin D decreases expression ISO Sarin results in decreased expression of CTSD mRNA CTD PMID:19522546 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cul4b cullin 4B decreases expression
increases expression
ISO Sarin results in decreased expression of CUL4B mRNA
Sarin results in increased expression of CUL4B mRNA
CTD PMID:19522546 NCBI chr  X:124,831,391...124,870,329
Ensembl chr  X:124,832,628...124,870,329
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Sarin results in decreased expression of CXCR4 mRNA CTD PMID:19522546 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyc1 cytochrome c-1 increases expression ISO Sarin results in increased expression of CYC1 mRNA CTD PMID:19522546 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Dag1 dystroglycan 1 decreases expression ISO Sarin results in decreased expression of DAG1 mRNA CTD PMID:19522546 NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
JBrowse link
G Dbh dopamine beta-hydroxylase decreases expression ISO Sarin results in decreased expression of DBH mRNA CTD PMID:19522546 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dbn1 drebrin 1 decreases expression ISO Sarin results in decreased expression of DBN1 mRNA CTD PMID:19522546 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dctn2 dynactin subunit 2 increases expression EXP Sarin results in increased expression of DCTN2 protein CTD PMID:28973502 NCBI chr 7:70,555,953...70,571,433
Ensembl chr 7:70,556,019...70,572,614
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 affects expression EXP Sarin affects the expression of DDAH1 protein CTD PMID:28973502 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Sarin results in decreased expression of DDC mRNA; Sarin results in decreased expression of DDC protein CTD PMID:19522546 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Dguok deoxyguanosine kinase decreases expression
increases expression
ISO Sarin results in decreased expression of DGUOK mRNA
Sarin results in increased expression of DGUOK mRNA
CTD PMID:19522546 NCBI chr 4:115,180,433...115,208,061
Ensembl chr 4:115,180,433...115,208,061
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP Sarin results in decreased expression of DLD protein CTD PMID:28973502 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression ISO Sarin results in decreased expression of DLK1 mRNA CTD PMID:19522546 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression EXP Sarin results in decreased expression of DLST protein CTD PMID:28973502 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression
increases expression
ISO Sarin results in decreased expression of DNAJA1 mRNA
Sarin results in increased expression of DNAJA1 mRNA
CTD PMID:19522546 NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 decreases expression ISO Sarin results in decreased expression of DNAJB2 mRNA CTD PMID:19522546 NCBI chr 9:82,436,453...82,444,669
Ensembl chr 9:82,436,458...82,444,668
JBrowse link
G Drd5 dopamine receptor D5 increases expression ISO Sarin results in increased expression of DRD5 mRNA CTD PMID:19522546 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression
increases expression
ISO Sarin results in decreased expression of DYNLL1 mRNA
Sarin results in increased expression of DYNLL1 mRNA
CTD PMID:19522546 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Efna4 ephrin A4 decreases expression ISO Sarin results in decreased expression of EFNA4 mRNA CTD PMID:19522546 NCBI chr 2:188,655,920...188,660,179
Ensembl chr 2:188,655,912...188,660,179
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 decreases expression
increases expression
ISO Sarin results in decreased expression of EID1 mRNA
Sarin results in increased expression of EID1 mRNA
CTD PMID:19522546 NCBI chr 3:117,938,500...117,940,219
Ensembl chr 3:117,938,500...117,940,219
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha decreases expression ISO Sarin results in decreased expression of EIF2B1 mRNA CTD PMID:19522546 NCBI chr12:37,444,136...37,452,391
Ensembl chr12:37,444,072...37,465,398
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO Sarin results in decreased expression of ELP1 mRNA CTD PMID:19522546 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798
JBrowse link
G Eno1 enolase 1 decreases expression EXP Sarin results in decreased expression of ENO1 protein CTD PMID:28973502 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno2 enolase 2 decreases expression EXP Sarin results in decreased expression of ENO2 protein CTD PMID:28973502 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 decreases expression ISO Sarin results in decreased expression of ENTPD8 mRNA CTD PMID:19522546 NCBI chr 3:2,286,363...2,299,720
Ensembl chr 3:2,288,667...2,302,782
JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression
increases expression
ISO Sarin results in decreased expression of ETFB mRNA
Sarin results in increased expression of ETFB mRNA
CTD PMID:19522546 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Sarin results in increased expression of ETS2 mRNA; Sarin results in increased expression of ETS2 protein CTD PMID:19522546 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G F12 coagulation factor XII decreases expression ISO Sarin results in decreased expression of F12 mRNA CTD PMID:19522546 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP Sarin results in decreased expression of FABP5 protein CTD PMID:28973502 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fbln1 fibulin 1 decreases expression ISO Sarin results in decreased expression of FBLN1 mRNA CTD PMID:19522546 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia increases expression ISO Sarin results in increased expression of FCER1A mRNA CTD PMID:19522546 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression
increases expression
ISO Sarin results in decreased expression of FEV mRNA
Sarin results in increased expression of FEV mRNA
CTD PMID:19522546 NCBI chr 9:82,142,981...82,146,855
Ensembl chr 9:82,142,981...82,146,874
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression ISO Sarin results in decreased expression of FTH1 mRNA CTD PMID:19522546 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Gabarap GABA type A receptor-associated protein decreases expression
increases expression
ISO Sarin results in decreased expression of GABARAP mRNA
Sarin results in increased expression of GABARAP mRNA
CTD PMID:19522546 NCBI chr10:56,601,288...56,604,223
Ensembl chr10:56,601,288...56,604,221
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 increases expression ISO Sarin results in increased expression of GABRG3 mRNA CTD PMID:19522546 NCBI chr 1:112,158,525...112,812,267
Ensembl chr 1:112,158,519...112,811,936
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression ISO Sarin results in decreased expression of GABRR1 mRNA CTD PMID:19522546 NCBI chr 5:48,374,048...48,411,170
Ensembl chr 5:48,374,096...48,411,170
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Sarin results in increased expression of GADD45A mRNA CTD PMID:19522546 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Sarin results in decreased expression of GAP43 mRNA CTD PMID:19522546 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Sarin results in increased expression of GC protein CTD PMID:26778279 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases expression ISO Sarin results in decreased expression of GCH1 mRNA CTD PMID:19522546 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
ISO
EXP
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein
Sarin results in increased expression of GFAP protein
CTD PMID:23692952, PMID:27639427 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Glo1 glyoxalase 1 increases expression EXP Sarin results in increased expression of GLO1 protein CTD PMID:28973502 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Glra1 glycine receptor, alpha 1 increases expression ISO Sarin results in increased expression of GLRA1 mRNA CTD PMID:19522546 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Gls glutaminase decreases expression ISO Sarin results in decreased expression of GLS mRNA CTD PMID:19522546 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression ISO Sarin results in decreased expression of GLUD1 mRNA CTD PMID:19522546 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Glul glutamate-ammonia ligase decreases expression
increases expression
ISO
EXP
Sarin results in decreased expression of GLUL mRNA
Sarin results in decreased expression of GLNS protein
Sarin results in increased expression of GLUL mRNA
CTD PMID:19522546, PMID:28973502 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gnas GNAS complex locus decreases expression ISO Sarin results in decreased expression of GNAS mRNA CTD PMID:19522546 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression ISO Sarin results in decreased expression of GPI mRNA CTD PMID:19522546 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gpr27 G protein-coupled receptor 27 increases expression ISO Sarin results in increased expression of GPR27 mRNA CTD PMID:19522546 NCBI chr 4:132,137,793...132,138,926
Ensembl chr 4:132,137,793...132,138,926
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO Sarin results in increased expression of GRIK5 mRNA CTD PMID:19522546 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression ISO Sarin results in increased expression of GRIN2B mRNA CTD PMID:19522546 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression ISO Sarin results in decreased expression of GSTA4 mRNA CTD PMID:19522546 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression ISO Sarin results in increased expression of GSTM5 mRNA CTD PMID:19522546 NCBI chr 2:210,761,729...210,766,501
Ensembl chr 2:210,761,729...210,766,501
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression ISO Sarin results in decreased expression of GSTT2 mRNA CTD PMID:19522546 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO Sarin results in decreased expression of GSTZ1 mRNA CTD PMID:19522546 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO Sarin results in decreased expression of HADHA mRNA CTD PMID:19522546 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP Sarin results in decreased expression of HBA1 protein CTD PMID:28973502 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression EXP Sarin results in decreased expression of HINT1 protein CTD PMID:28973502 NCBI chr10:40,208,236...40,211,981
Ensembl chr10:40,208,223...40,211,975
JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases expression ISO Sarin results in increased expression of HIPK2 mRNA CTD PMID:19522546 NCBI chr 4:66,438,390...66,625,183
Ensembl chr 4:66,445,266...66,624,912
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression EXP Sarin results in decreased expression of HNRNPH1 protein CTD PMID:28973502 NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910
JBrowse link
G Hp haptoglobin decreases expression EXP Sarin results in decreased expression of HP protein CTD PMID:26778279 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hpx hemopexin decreases expression EXP Sarin results in decreased expression of HPX protein CTD PMID:26778279 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression
increases expression
ISO Sarin results in decreased expression of HSPA4 mRNA
Sarin results in increased expression of HSPA4 mRNA
CTD PMID:19522546 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression EXP Sarin results in decreased expression of HSPA8 protein CTD PMID:28973502 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression EXP Sarin affects the expression of HSPA9 protein CTD PMID:28973502 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression EXP Sarin affects the expression of HSPD1 protein CTD PMID:28973502 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Sarin results in decreased expression of IDS mRNA CTD PMID:19522546 NCBI chr 8:69,447,971...69,466,708
Ensembl chr 8:69,449,801...69,466,618
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Sarin results in decreased expression of IFRD1 mRNA CTD PMID:19522546 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Il17rc interleukin 17 receptor C increases expression ISO Sarin results in increased expression of IL17RC mRNA CTD PMID:19522546 NCBI chr 4:145,426,647...145,439,845
Ensembl chr 4:145,427,367...145,439,843
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Sarin results in increased expression of IL1B mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein
CTD PMID:17301067, PMID:23692952 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 increases expression ISO Sarin results in increased expression of IL22RA1 mRNA CTD PMID:19522546 NCBI chr 5:154,078,093...154,102,903
Ensembl chr 5:154,077,944...154,106,433
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha increases expression ISO Sarin results in increased expression of IL27RA mRNA CTD PMID:19522546 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Il6 interleukin 6 increases expression EXP Sarin results in increased expression of IL6 mRNA CTD PMID:17301067 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ilf2 interleukin enhancer binding factor 2 decreases expression
increases expression
ISO Sarin results in decreased expression of ILF2 mRNA
Sarin results in increased expression of ILF2 mRNA
CTD PMID:19522546 NCBI chr 2:189,857,587...189,877,777
Ensembl chr 2:189,857,587...189,877,743
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression EXP Sarin results in decreased expression of INA protein CTD PMID:28973502 NCBI chr 1:266,782,835...266,794,389
Ensembl chr 1:266,781,617...266,794,431
JBrowse link
G Insig1 insulin induced gene 1 increases expression
decreases expression
ISO Sarin results in increased expression of INSIG1 mRNA
Sarin results in decreased expression of INSIG1 mRNA
CTD PMID:19522546 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 decreases expression ISO Sarin results in decreased expression of IQGAP1 mRNA CTD PMID:19522546 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO Sarin results in decreased expression of IRF2 mRNA CTD PMID:19522546 NCBI chr16:48,582,354...48,732,129
Ensembl chr16:48,582,026...48,732,932
JBrowse link
G Itm2b integral membrane protein 2B decreases expression ISO Sarin results in decreased expression of ITM2B mRNA CTD PMID:19522546 NCBI chr15:55,254,703...55,277,713
Ensembl chr15:55,254,706...55,277,713
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 decreases expression ISO Sarin results in decreased expression of ITPR1 mRNA CTD PMID:19522546 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Kat5 lysine acetyltransferase 5 decreases expression ISO Sarin results in decreased expression of KAT5 mRNA CTD PMID:19522546 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression
increases expression
ISO Sarin results in decreased expression of KAT6B mRNA
Sarin results in increased expression of KAT6B mRNA
CTD PMID:19522546 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 decreases expression
increases expression
ISO Sarin results in decreased expression of KCNJ8 mRNA
Sarin results in increased expression of KCNJ8 mRNA
CTD PMID:19522546 NCBI chr 4:176,783,287...176,789,143
Ensembl chr 4:176,782,498...176,789,304
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression ISO Sarin results in decreased expression of LAMP2 mRNA CTD PMID:19522546 NCBI chr  X:124,722,628...124,766,079
Ensembl chr  X:124,722,628...124,766,044
JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 decreases expression ISO Sarin results in decreased expression of LAMTOR2 mRNA CTD PMID:19522546 NCBI chr 2:187,911,530...187,914,930
Ensembl chr 2:187,911,533...187,915,596
JBrowse link
G Lasp1 LIM and SH3 protein 1 decreases expression EXP Sarin results in decreased expression of LASP1 protein CTD PMID:28973502 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Lin7c lin-7 homolog C, crumbs cell polarity complex component increases expression ISO Sarin results in increased expression of LIN7C mRNA CTD PMID:19522546 NCBI chr 3:101,010,923...101,018,235
Ensembl chr 3:101,010,899...101,018,433
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression ISO Sarin results in decreased expression of LITAF mRNA CTD PMID:19522546 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Lrp8 LDL receptor related protein 8 increases expression ISO Sarin results in increased expression of LRP8 mRNA CTD PMID:19522546 NCBI chr 5:127,404,348...127,476,636
Ensembl chr 5:127,404,450...127,476,641
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP Sarin results in decreased expression of MAP2 protein CTD PMID:27639427 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO Sarin results in decreased expression of MAP2K2 mRNA CTD PMID:19522546 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Sarin results in decreased expression of MAPT mRNA CTD PMID:19522546 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Sarin results in decreased expression of MARCKS mRNA CTD PMID:19522546 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression
increases expression
ISO Sarin results in decreased expression of MCL1 mRNA
Sarin results in increased expression of MCL1 mRNA
CTD PMID:19522546 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression
increases expression
ISO Sarin results in decreased expression of MFAP4 mRNA
Sarin results in increased expression of MFAP4 mRNA
CTD PMID:19522546 NCBI chr10:47,765,463...47,768,484
Ensembl chr10:47,765,432...47,768,483
JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO Sarin results in decreased expression of MFN1 mRNA CTD PMID:19522546 NCBI chr 2:118,929,738...118,971,689
Ensembl chr 2:118,929,738...118,973,698
JBrowse link
G Mif macrophage migration inhibitory factor increases expression EXP Sarin results in increased expression of MIF protein CTD PMID:28973502 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mpdu1 mannose-P-dolichol utilization defect 1 decreases expression ISO Sarin results in decreased expression of MPDU1 mRNA CTD PMID:19522546 NCBI chr10:56,261,636...56,267,213
Ensembl chr10:56,261,637...56,267,213
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Sarin results in decreased expression of MPZL1 mRNA CTD PMID:19522546 NCBI chr13:83,805,244...83,842,074
Ensembl chr13:83,805,244...83,842,051
JBrowse link
G Mrps28 mitochondrial ribosomal protein S28 decreases expression ISO Sarin results in decreased expression of MRPS28 mRNA CTD PMID:19522546 NCBI chr 2:95,077,577...95,080,825
Ensembl chr 2:95,045,034...95,173,753
JBrowse link
G Mtmr2 myotubularin related protein 2 decreases expression ISO Sarin results in decreased expression of MTMR2 mRNA CTD PMID:19522546 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Sarin results in increased expression of PZP protein CTD PMID:26778279 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Musk muscle associated receptor tyrosine kinase increases expression ISO Sarin results in increased expression of MUSK mRNA CTD PMID:19522546 NCBI chr 5:75,392,790...75,498,694
Ensembl chr 5:75,392,790...75,498,694
JBrowse link
G Naca nascent polypeptide associated complex subunit alpha decreases expression ISO Sarin results in decreased expression of NACA mRNA CTD PMID:19522546 NCBI chr 7:2,458,283...2,470,674
Ensembl chr 7:2,458,264...2,470,674
JBrowse link
G Napg NSF attachment protein gamma decreases expression EXP Sarin results in decreased expression of NAPG protein CTD PMID:28973502 NCBI chr18:58,325,319...58,344,071
Ensembl chr18:58,325,319...58,344,070
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases expression ISO Sarin results in decreased expression of NCOR1 mRNA CTD PMID:19522546 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO Sarin results in decreased expression of NDUFS4 mRNA CTD PMID:19522546 NCBI chr 2:46,372,488...46,476,162
Ensembl chr 2:46,372,518...46,476,203
JBrowse link
G Nefh neurofilament heavy increases phosphorylation EXP Sarin results in increased phosphorylation of NEFH protein CTD PMID:21439362 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects localization EXP Sarin affects the localization of NFKB1 protein CTD PMID:17301067 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Ngrn neugrin, neurite outgrowth associated decreases expression ISO Sarin results in decreased expression of NGRN mRNA CTD PMID:19522546 NCBI chr 1:142,050,458...142,056,336
Ensembl chr 1:142,050,458...142,056,336
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression EXP Sarin results in decreased expression of NME1 protein CTD PMID:28973502 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Sarin affects the expression of NME2 protein CTD PMID:28973502 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nmu neuromedin U decreases expression ISO Sarin results in decreased expression of NMU mRNA CTD PMID:19522546 NCBI chr14:34,353,683...34,381,968
Ensembl chr14:34,354,503...34,381,828
JBrowse link
G Nosip nitric oxide synthase interacting protein increases expression ISO Sarin results in increased expression of NOSIP mRNA CTD PMID:19522546 NCBI chr 1:101,055,571...101,072,938
Ensembl chr 1:101,055,622...101,072,938
JBrowse link
G Notch2 notch receptor 2 decreases expression ISO Sarin results in decreased expression of NOTCH2 mRNA CTD PMID:19522546 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Sarin results in decreased expression of NQO1 mRNA CTD PMID:19522546 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 decreases expression ISO Sarin results in decreased expression of NQO2 mRNA CTD PMID:19522546 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO Sarin results in decreased expression of NRCAM mRNA CTD PMID:19522546 NCBI chr 6:64,297,843...64,867,408
Ensembl chr 6:64,297,888...64,864,996
JBrowse link
G Nrp1 neuropilin 1 decreases expression
increases expression
ISO Sarin results in decreased expression of NRP1 mRNA
Sarin results in increased expression of NRP1 mRNA
CTD PMID:19522546 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Sarin results in increased expression of NTRK2 mRNA CTD PMID:19522546 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO Sarin results in increased expression of NTRK3 mRNA CTD PMID:19522546 NCBI chr 1:139,890,537...140,262,503
Ensembl chr 1:139,890,560...140,262,503
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression
increases expression
ISO Sarin results in decreased expression of OLR1 mRNA
Sarin results in increased expression of OLR1 mRNA
CTD PMID:19522546 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Osmr oncostatin M receptor increases expression ISO Sarin results in increased expression of OSMR mRNA CTD PMID:19522546 NCBI chr 2:56,107,491...56,163,522
Ensembl chr 2:56,110,777...56,151,531
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Sarin results in decreased expression of P4HB mRNA CTD PMID:19522546 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Sarin results in decreased expression of PANK3 mRNA CTD PMID:19522546 NCBI chr10:20,591,432...20,615,258
Ensembl chr10:20,591,432...20,615,258
JBrowse link
G Park7 Parkinsonism associated deglycase decreases expression ISO
EXP
Sarin results in decreased expression of PARK7 mRNA
Sarin results in decreased expression of PARK7 protein
CTD PMID:19522546, PMID:28973502 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Parl presenilin associated, rhomboid-like decreases expression ISO Sarin results in decreased expression of PARL mRNA CTD PMID:19522546 NCBI chr11:84,517,368...84,544,463
Ensembl chr11:84,517,368...84,544,462
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Sarin results in decreased expression of PCMT1 mRNA CTD PMID:19522546 NCBI chr 1:1,734,863...1,767,759
Ensembl chr 1:1,736,276...1,767,618
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression
increases expression
ISO
EXP
Sarin results in decreased expression of PDHB mRNA
Sarin results in decreased expression of PDHB protein
Sarin results in increased expression of PDHB mRNA
CTD PMID:19522546, PMID:28973502 NCBI chr15:18,540,826...18,546,855
Ensembl chr15:18,539,210...18,546,854
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Sarin affects the expression of PDIA3 protein CTD PMID:28973502 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression ISO Sarin results in decreased expression of PEMT mRNA CTD PMID:19522546 NCBI chr10:46,339,821...46,404,640
Ensembl chr10:46,339,821...46,404,642
JBrowse link
G Pepd peptidase D increases hydrolysis ISO PEPD protein results in increased hydrolysis of Sarin CTD PMID:20176006, PMID:22120822, PMID:22677456 NCBI chr 1:90,820,670...91,285,128 JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression ISO Sarin results in decreased expression of PFKP mRNA CTD PMID:19522546 NCBI chr17:68,510,765...68,574,387
Ensembl chr17:68,511,064...68,559,471
JBrowse link
G Pfn2 profilin 2 decreases expression EXP Sarin results in decreased expression of PFN2 protein CTD PMID:28973502 NCBI chr 2:147,953,858...147,959,692
Ensembl chr 2:147,955,196...148,050,438
JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression
increases expression
ISO Sarin results in decreased expression of PLA2G5 mRNA
Sarin results in increased expression of PLA2G5 mRNA
CTD PMID:19522546 NCBI chr 5:157,247,601...157,268,968
Ensembl chr 5:157,247,781...157,268,903
JBrowse link
G Pla2g6 phospholipase A2 group VI increases expression ISO Sarin results in increased expression of PLA2G6 mRNA CTD PMID:19522546 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Plaa phospholipase A2, activating protein increases expression ISO Sarin results in increased expression of PLAA mRNA CTD PMID:19522546 NCBI chr 5:113,548,913...113,578,928
Ensembl chr 5:113,548,913...113,578,928
JBrowse link
G Pltp phospholipid transfer protein decreases expression ISO Sarin results in decreased expression of PLTP mRNA CTD PMID:19522546 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression ISO Sarin results in decreased expression of PMP22 mRNA CTD PMID:19522546 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Pnma1 PNMA family member 1 decreases expression
increases expression
ISO Sarin results in decreased expression of PNMA1 mRNA
Sarin results in increased expression of PNMA1 mRNA
CTD PMID:19522546 NCBI chr 6:107,631,227...107,633,012
Ensembl chr 6:107,631,227...107,633,012
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity ISO Sarin results in decreased activity of PNPLA6 protein CTD PMID:8486913 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Pomc proopiomelanocortin decreases expression EXP Sarin results in decreased expression of POMC protein CTD PMID:17301067 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
increases hydrolysis
decreases response to substance
ISO PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]
PON1 protein mutant form results in increased hydrolysis of Sarin; PON1 protein results in increased hydrolysis of Sarin
PON1 protein mutant form results in decreased susceptibility to Sarin
CTD PMID:16331452, PMID:20176006, PMID:21329748, PMID:23159884 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression
increases expression
ISO Sarin results in decreased expression of POR mRNA
Sarin results in increased expression of POR mRNA
CTD PMID:19522546 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO Sarin results in decreased expression of PPP1CA mRNA CTD PMID:19522546 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 decreases expression ISO Sarin results in decreased expression of PPT1 mRNA CTD PMID:19522546 NCBI chr 5:140,538,260...140,558,163
Ensembl chr 5:140,538,260...140,558,162
JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression EXP Sarin results in decreased expression of PRDX6 protein CTD PMID:28973502 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO Sarin results in increased expression of PRKCB mRNA CTD PMID:19522546 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prss12 serine protease 12 decreases expression ISO Sarin results in decreased expression of PRSS12 mRNA CTD PMID:19522546 NCBI chr 2:227,657,983...227,717,884
Ensembl chr 2:227,657,983...227,717,884
JBrowse link
G Psen1 presenilin 1 decreases expression ISO Sarin results in decreased expression of PSEN1 mRNA; Sarin results in decreased expression of PSEN1 protein CTD PMID:19522546 NCBI chr 6:107,169,514...107,221,000
Ensembl chr 6:107,169,528...107,216,798
JBrowse link
G Psen2 presenilin 2 decreases expression ISO Sarin results in decreased expression of PSEN2 mRNA CTD PMID:19522546 NCBI chr13:98,513,600...98,539,347
Ensembl chr13:98,513,570...98,530,724
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP Sarin results in increased expression of PSMA1 protein CTD PMID:28973502 NCBI chr 1:183,733,567...183,744,586
Ensembl chr 1:183,733,567...183,744,586
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression
increases expression
ISO Sarin results in decreased expression of PSMA3 mRNA
Sarin results in increased expression of PSMA3 mRNA
CTD PMID:19522546 NCBI chr 6:93,423,029...93,444,223
Ensembl chr 6:93,423,002...93,444,240
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 decreases expression ISO Sarin results in decreased expression of PSMD8 mRNA CTD PMID:19522546 NCBI chr 1:88,116,811...88,123,643
Ensembl chr 1:88,116,812...88,123,643
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R decreases expression ISO Sarin results in decreased expression of PTPRR mRNA CTD PMID:19522546 NCBI chr 7:59,039,717...59,325,925
Ensembl chr 7:59,039,720...59,325,947
JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Sarin results in decreased expression of PTS mRNA CTD PMID:19522546 NCBI chr 8:54,954,261...54,961,271
Ensembl chr 8:54,954,226...54,961,265
JBrowse link
G Pura purine rich element binding protein A affects expression EXP Sarin affects the expression of PURA protein CTD PMID:28973502 NCBI chr18:29,104,712...29,114,918
Ensembl chr18:29,110,242...29,111,156
JBrowse link
G Ranbp1 RAN binding protein 1 decreases expression ISO Sarin results in decreased expression of RANBP1 mRNA CTD PMID:19522546 NCBI chr11:86,890,585...86,898,818
Ensembl chr11:86,890,585...86,898,818
JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 increases expression ISO Sarin results in increased expression of RASGRP2 mRNA CTD PMID:19522546 NCBI chr 1:221,771,238...221,788,765
Ensembl chr 1:221,773,254...221,788,765
JBrowse link
G Rfxank regulatory factor X-associated ankyrin-containing protein decreases expression ISO Sarin results in decreased expression of RFXANK mRNA CTD PMID:19522546 NCBI chr16:21,029,449...21,037,080
Ensembl chr16:21,029,596...21,037,078
JBrowse link
G Rgn regucalcin increases hydrolysis ISO RGN protein results in increased hydrolysis of Sarin CTD PMID:20176006 NCBI chr  X:1,833,484...1,848,904
Ensembl chr  X:1,833,492...1,848,904
JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Sarin results in decreased expression of RGS4 mRNA CTD PMID:19522546 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rtn3 reticulon 3 decreases expression ISO Sarin results in decreased expression of RTN3 mRNA CTD PMID:19522546 NCBI chr 1:222,677,359...222,734,307
Ensembl chr 1:222,677,365...222,734,241
JBrowse link
G Scarb2 scavenger receptor class B, member 2 decreases expression ISO Sarin results in decreased expression of SCARB2 mRNA CTD PMID:19522546 NCBI chr14:17,064,173...17,115,620
Ensembl chr14:17,064,353...17,115,963
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
increases expression
ISO Sarin results in decreased expression of SCD mRNA
Sarin results in increased expression of SCD mRNA
CTD PMID:19522546 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 increases expression ISO Sarin results in increased expression of SCN10A mRNA CTD PMID:19522546 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Sarin results in decreased expression of SDCBP mRNA CTD PMID:19522546 NCBI chr 5:19,471,664...19,498,499
Ensembl chr 5:19,471,664...19,498,485
JBrowse link
G Septin5 septin 5 increases expression EXP Sarin results in increased expression of SEPTIN5 protein CTD PMID:28973502 NCBI chr11:86,516,377...86,522,169
Ensembl chr11:86,512,797...86,522,168
JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO Sarin results in decreased expression of SERPINI1 mRNA CTD PMID:19522546 NCBI chr 2:174,013,058...174,111,693
Ensembl chr 2:174,013,288...174,111,752
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Sarin results in decreased expression of SGK1 mRNA CTD PMID:19522546 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 decreases expression EXP Sarin results in decreased expression of SH3GL1 protein CTD PMID:28973502 NCBI chr 9:11,031,847...11,055,285
Ensembl chr 9:11,031,841...11,055,285
JBrowse link
G Slc18a3 solute carrier family 18 member A3 decreases expression EXP Sarin results in decreased expression of SLC18A3 protein CTD PMID:22640809 NCBI chr16:8,682,668...8,685,529
Ensembl chr16:8,682,669...8,685,529
JBrowse link
G Slc20a1 solute carrier family 20 member 1 decreases expression ISO Sarin results in decreased expression of SLC20A1 mRNA CTD PMID:19522546 NCBI chr 3:121,725,204...121,739,160
Ensembl chr 3:121,725,859...121,739,173
JBrowse link
G Slc6a15 solute carrier family 6 member 15 decreases expression ISO Sarin results in decreased expression of SLC6A15 mRNA CTD PMID:19522546 NCBI chr 7:45,328,207...45,381,920
Ensembl chr 7:45,328,105...45,382,229
JBrowse link
G Snca synuclein alpha decreases expression ISO
EXP
Sarin results in decreased expression of SNCA mRNA
Sarin results in decreased expression of SNCA protein
CTD PMID:19522546, PMID:28973502 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression
increases expression
ISO Sarin results in decreased expression of SOCS5 mRNA
Sarin results in increased expression of SOCS5 mRNA
CTD PMID:19522546 NCBI chr 6:10,671,311...10,705,610
Ensembl chr 6:10,674,371...10,704,977
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP Sarin results in decreased expression of SOD1 protein CTD PMID:28973502 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Spast spastin decreases expression ISO Sarin results in decreased expression of SPG4 mRNA CTD PMID:19522546 NCBI chr 6:22,230,067...22,282,166
Ensembl chr 6:22,230,928...22,281,886
JBrowse link
G Stip1 stress-induced phosphoprotein 1 affects expression EXP Sarin affects the expression of STIP1 protein CTD PMID:28973502 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Sarin results in decreased expression of STMN1 protein CTD PMID:28973502 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Stmn2 stathmin 2 decreases expression ISO Sarin results in decreased expression of STMN2 mRNA CTD PMID:19522546 NCBI chr 2:95,424,251...95,471,900
Ensembl chr 2:95,424,251...95,472,115
JBrowse link
G Stx4 syntaxin 4 decreases expression ISO Sarin results in decreased expression of STX4A mRNA CTD PMID:19522546 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Syt1 synaptotagmin 1 increases expression ISO Sarin results in increased expression of SYT1 mRNA CTD PMID:19522546 NCBI chr 7:50,084,063...50,638,996
Ensembl chr 7:50,084,060...50,638,798
JBrowse link
G Tagln3 transgelin 3 increases expression EXP Sarin results in increased expression of TAGLN3 protein CTD PMID:28973502 NCBI chr11:60,072,983...60,086,552
Ensembl chr11:60,072,727...60,086,553
JBrowse link
G Tbcc tubulin folding cofactor C decreases expression
increases expression
ISO Sarin results in decreased expression of TBCC mRNA
Sarin results in increased expression of TBCC mRNA
CTD PMID:19522546 NCBI chr 9:16,405,187...16,406,338
Ensembl chr 9:16,405,185...16,406,338
JBrowse link
G Tcfl5 transcription factor like 5 decreases expression ISO Sarin results in decreased expression of TCFL5 mRNA CTD PMID:19522546 NCBI chr 3:176,124,846...176,144,531
Ensembl chr 3:176,125,482...176,144,531
JBrowse link
G Tf transferrin affects binding ISO Sarin binds to TF protein
Sarin binds to TRF protein
CTD PMID:18930948 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfrc transferrin receptor decreases expression ISO Sarin results in decreased expression of TFRC mRNA CTD PMID:19522546 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tm2d1 TM2 domain containing 1 increases expression ISO Sarin results in increased expression of TM2D1 mRNA CTD PMID:19522546 NCBI chr 5:116,992,405...117,038,882
Ensembl chr 5:116,996,652...117,038,882
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 decreases expression ISO Sarin results in decreased expression of TMED10 mRNA CTD PMID:19522546 NCBI chr 6:109,169,739...109,205,004
Ensembl chr 6:109,169,741...109,205,004
JBrowse link
G Tmsb15b2 thymosin beta 15B2 decreases expression ISO Sarin results in decreased expression of TMSB15A mRNA CTD PMID:19522546 NCBI chr  X:107,612,518...107,614,632
Ensembl chr  X:107,612,518...107,614,632
JBrowse link
G Tnf tumor necrosis factor increases expression EXP Sarin results in increased expression of TNF mRNA CTD PMID:17301067 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Sarin results in increased expression of TNFRSF9 mRNA CTD PMID:19522546 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO Sarin results in decreased expression of TOP2A mRNA CTD PMID:19522546 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tpi1 triosephosphate isomerase 1 affects expression EXP Sarin affects the expression of TPI1 protein CTD PMID:28973502 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
JBrowse link
G Tpm1 tropomyosin 1 decreases expression ISO Sarin results in decreased expression of TPM1 mRNA CTD PMID:19522546 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Traf5 TNF receptor-associated factor 5 increases expression ISO Sarin results in increased expression of TRAF5 mRNA CTD PMID:19522546 NCBI chr13:110,758,556...110,801,871
Ensembl chr13:110,758,761...110,784,209
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 increases expression ISO Sarin results in increased expression of TRPM3 mRNA CTD PMID:19522546 NCBI chr 1:239,741,572...240,757,583
Ensembl chr 1:240,355,149...240,757,583
JBrowse link
G Tspan3 tetraspanin 3 decreases expression ISO Sarin results in decreased expression of TSPAN3 mRNA CTD PMID:19522546 NCBI chr 8:60,806,848...60,830,448
Ensembl chr 8:60,806,849...60,830,448
JBrowse link
G Tspo translocator protein increases expression EXP Sarin results in increased expression of TSPO mRNA; Sarin results in increased expression of TSPO protein CTD PMID:27639427 NCBI chr 7:124,460,358...124,470,610
Ensembl chr 7:124,460,358...124,470,609
JBrowse link
G Tubb2b tubulin, beta 2B class IIb decreases expression EXP Sarin results in decreased expression of TUBB2B protein CTD PMID:28973502 NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression EXP Sarin results in decreased expression of TUBB3 protein CTD PMID:28973502 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression ISO Sarin results in decreased expression of TUBG1 mRNA CTD PMID:19522546 NCBI chr10:89,030,865...89,037,455
Ensembl chr10:89,030,865...89,037,455
JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 decreases expression ISO Sarin results in decreased expression of UBE2G1 mRNA CTD PMID:19522546 NCBI chr10:59,173,268...59,254,458
Ensembl chr10:59,173,268...59,254,453
JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M decreases expression ISO Sarin results in decreased expression of UBE2M mRNA CTD PMID:19522546 NCBI chr 1:65,537,640...65,541,177
Ensembl chr 1:65,537,640...65,541,177
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 affects expression EXP Sarin affects the expression of UCHL1 protein CTD PMID:28973502 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Sarin results in decreased expression of UCHL3 mRNA CTD PMID:19522546 NCBI chr15:86,153,624...86,198,127
Ensembl chr15:86,153,628...86,198,127
JBrowse link
G Usp14 ubiquitin specific peptidase 14 decreases expression ISO Sarin results in decreased expression of USP14 mRNA CTD PMID:19522546 NCBI chr18:1,178,785...1,216,573
Ensembl chr18:1,178,787...1,216,409
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 decreases expression ISO Sarin results in decreased expression of VAMP3 mRNA CTD PMID:19522546 NCBI chr 5:168,126,157...168,136,628
Ensembl chr 5:168,126,157...168,136,666
JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression ISO Sarin results in increased expression of VDAC1 mRNA CTD PMID:19522546 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression
increases expression
ISO Sarin results in decreased expression of YWHAB mRNA
Sarin results in increased expression of YWHAB mRNA
CTD PMID:19522546 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon decreases expression ISO Sarin results in decreased expression of YWHAE mRNA CTD PMID:19522546 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 decreases expression ISO Sarin results in decreased expression of ZEB1 mRNA CTD PMID:19522546 NCBI chr17:54,656,627...54,714,920
Ensembl chr17:54,658,463...54,714,914
JBrowse link
G Zfp532 zinc finger protein 532 decreases expression ISO Sarin results in decreased expression of ZNF532 mRNA CTD PMID:19522546 NCBI chr18:61,257,522...61,368,371
Ensembl chr18:61,258,911...61,368,371
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        aetiopathogenetic role 18936
          neurotoxin 17549
            (S)-sarin 289
              sarin 289
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            heteroorganic entity 19147
                              organochalcogen compound 18855
                                organooxygen compound 18777
                                  ester 15705
                                    phosphinic ester 310
                                      isopropyl methylphosphonofluoridate 289
                                        (S)-sarin 289
                                          sarin 289
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.