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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(S)-sarin
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Accession:CHEBI:75871 term browser browse the term
Definition:The (S)-enantiomer of sarin; the more potent enantiomer of racemic sarin, a nerve agent that is employed as a chemical warfare agent.
Synonyms:exact_synonym: isopropyl (S)-methylphosphonofluoridate
 related_synonym: Formula=C4H10FO2P;   InChI=1S/C4H10FO2P/c1-4(2)7-8(3,5)6/h4H,1-3H3/t8-/m0/s1;   InChIKey=DYAHQFWOVKZOOW-QMMMGPOBSA-N;   SMILES=CC(C)O[P@@](C)(F)=O;   sarin
 xref: CAS:6171-94-4;   Reaxys:2409983;   Wikipedia:Sarin
 cyclic_relationship: is_enantiomer_of CHEBI:75872


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sarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO Sarin results in decreased expression of ABCB1 mRNA CTD PMID:19522546 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 decreases expression ISO Sarin results in decreased expression of ABCD3 mRNA CTD PMID:19522546 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abcf2 ATP binding cassette subfamily F member 2 decreases expression
increases expression
ISO Sarin results in decreased expression of ABCF2 mRNA
Sarin results in increased expression of ABCF2 mRNA
CTD PMID:19522546 NCBI chr 4:10,594,802...10,607,606
Ensembl chr 4:10,594,907...10,607,606
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression ISO Sarin results in decreased expression of ACAA2 mRNA CTD PMID:19522546 NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 decreases expression
increases expression
ISO Sarin results in decreased expression of ACAT2 mRNA
Sarin results in increased expression of ACAT2 mRNA
CTD PMID:19522546 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Ache acetylcholinesterase increases metabolic processing
affects binding
affects expression
decreases activity
multiple interactions
increases phosphorylation
decreases expression
increases activity
ISO
EXP
Sarin results in increased metabolism of ACHE protein; Sarin results in increased metabolism of ACHE protein mutant form
asoxime chloride binds to [Sarin binds to ACHE protein]
Sarin affects the expression of ACHE mRNA
Sarin analog results in decreased activity of ACHE protein; Sarin metabolite results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein
1-((4-(aminocarbonyl)pyridinio)trimethylene)-2-((hydroxyimino)methyl)pyridinium inhibits the reaction [Sarin results in decreased activity of ACHE protein]; 4-amino-2-((diethylamino)methyl)phenol analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Obidoxime Chloride co-treated with asoxime chloride] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride affects the reaction [Sarin results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; benzohydroxamic acid analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; diacetylmonoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Donepezil promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Edrophonium promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Galantamine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; HLo 7 affects the reaction [Sarin results in decreased activity of ACHE protein]; Imipramine inhibits the reaction [asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; Imipramine promotes the reaction [Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]]; isonitrosoacetone inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; isonitrosoacetone inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N,N'-p-xylene-bis-((2,2'-hydroxyiminomethyl)pyridinium) dibromide inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin metabolite results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pralidoxime Compounds inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pralidoxime metabolite inhibits the reaction [Sarin results in decreased activity of ACHE protein]; pyridine-4-aldoxime analog inhibits the reaction [Sarin results in decreased activity of ACHE protein]; RS194B analog inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; RS194B inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; RS41A inhibits the reaction [Sarin binds to and results in decreased activity of ACHE protein]; Sarin binds to and results in decreased activity of ACHE protein
Sarin results in increased phosphorylation of ACHE protein
Sarin analog results in decreased activity of ACHE protein; Sarin results in decreased activity of ACHE protein
asoxime chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; BI 6 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Cholinesterase Reactivators inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Sarin results in decreased activity of ACHE protein]; N(6)-cyclopentyladenosine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Physostigmine affects the reaction [Sarin affects the expression of ACHE mRNA]; Physostigmine affects the reaction [Sarin affects the expression of and affects the activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Pyridinium Compounds inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Sarin affects the expression of and affects the activity of ACHE protein; Trimedoxime inhibits the reaction [Sarin analog results in decreased activity of ACHE protein]; Trimedoxime inhibits the reaction [Sarin results in decreased activity of ACHE protein]
[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [[1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide co-treated with cucurbit(7)uril] co-treated with Atropine] inhibits the reaction [Sarin results in decreased activity of ACHE protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in decreased activity of ACHE protein; Atropine inhibits the reaction [Sarin results in decreased activity of ACHE protein]; Sarin binds to and results in increased phosphorylation of and results in decreased activity of ACHE protein
Sarin results in decreased expression of ACHE mRNA
Sarin results in increased activity of ACHE protein
CTD PMID:1609424 PMID:12415428 PMID:14631503 PMID:16025528 PMID:17370251 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acly ATP citrate lyase decreases expression ISO Sarin results in decreased expression of ACLY mRNA CTD PMID:19522546 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Add1 adducin 1 decreases expression ISO Sarin results in decreased expression of ADD1 mRNA CTD PMID:19522546 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adora1 adenosine A1 receptor increases expression ISO Sarin results in increased expression of ADORA1 mRNA CTD PMID:19522546 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Sarin results in decreased expression of ADORA2A mRNA CTD PMID:19522546 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Agrn agrin decreases expression ISO Sarin results in decreased expression of AGRN mRNA CTD PMID:19522546 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003
JBrowse link
G Ahcy adenosylhomocysteinase decreases expression ISO Sarin results in decreased expression of AHCY mRNA CTD PMID:19522546 NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Sarin results in decreased expression of AK1 protein CTD PMID:28973502 NCBI chr 3:15,912,431...15,923,045 JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Sarin results in decreased expression of AK3 mRNA CTD PMID:19522546 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625
JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression
increases expression
ISO Sarin results in decreased expression of AKAP9 mRNA
Sarin results in increased expression of AKAP9 mRNA
CTD PMID:19522546 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Alb albumin affects binding
increases expression
ISO
EXP
Sarin binds to ALB protein
Sarin results in increased expression of ALB protein
CTD PMID:17188226 PMID:28973502 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO Sarin results in decreased expression of ALDOA mRNA CTD PMID:19522546 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C affects expression EXP Sarin affects the expression of ALDOC protein CTD PMID:28973502 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO Sarin results in decreased expression of AMACR mRNA CTD PMID:19522546 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression ISO Sarin results in increased expression of APBB3 mRNA CTD PMID:19522546 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Aplp1 amyloid beta precursor like protein 1 increases expression ISO Sarin results in increased expression of APLP1 mRNA CTD PMID:19522546 NCBI chr 1:85,696,880...85,707,215
Ensembl chr 1:85,696,882...85,707,155
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression EXP Sarin results in decreased expression of APOA1 protein CTD PMID:26778279 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Apoc4 apolipoprotein C4 increases expression ISO Sarin results in increased expression of APOC4 mRNA CTD PMID:19522546 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
JBrowse link
G Apoe apolipoprotein E increases expression ISO Sarin results in increased expression of APOE mRNA; Sarin results in increased expression of APOE protein CTD PMID:19522546 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G App amyloid beta precursor protein decreases expression ISO Sarin results in decreased expression of APP mRNA CTD PMID:19522546 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Arpc5l actin related protein 2/3 complex, subunit 5-like increases expression EXP Sarin results in increased expression of ARPC5L protein CTD PMID:28973502 NCBI chr 3:22,758,710...22,767,520
Ensembl chr 3:22,759,876...22,767,538
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 decreases expression
increases expression
ISO Sarin results in decreased expression of ASCL1 mRNA
Sarin results in increased expression of ASCL1 mRNA
CTD PMID:19522546 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993
JBrowse link
G Asl argininosuccinate lyase decreases expression ISO Sarin results in decreased expression of ASL mRNA CTD PMID:19522546 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression ISO Sarin results in decreased expression of ATP1B1 mRNA CTD PMID:19522546 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d decreases expression EXP Sarin results in decreased expression of ATP5H protein CTD PMID:28973502 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Sarin results in decreased expression of ATP5PO mRNA CTD PMID:19522546 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 decreases expression ISO Sarin results in decreased expression of ATP6V0A2 mRNA CTD PMID:19522546 NCBI chr12:31,949,863...31,979,777 JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 decreases expression ISO Sarin results in decreased expression of ATP6V0E mRNA CTD PMID:19522546 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434
JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) increases expression ISO Sarin results in increased expression of ATP9B mRNA CTD PMID:19522546 NCBI chr18:74,176,863...74,368,993
Ensembl chr18:74,176,863...74,368,953
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO Sarin results in decreased expression of B2M mRNA CTD PMID:19522546 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bag1 BAG cochaperone 1 decreases expression
increases expression
ISO Sarin results in decreased expression of BAG1 mRNA
Sarin results in increased expression of BAG1 mRNA
CTD PMID:19522546 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
ISO
EXP
Sarin results in increased expression of BAX mRNA
Sarin affects the expression of BAX mRNA; Sarin affects the expression of BAX protein
CTD PMID:19522546 PMID:27639427 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
decreases response to substance
increases phosphorylation
decreases expression
affects binding
ISO
EXP
asoxime chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; N,N'-monomethylenebis(pyridiniumaldoxime) inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Obidoxime Chloride inhibits the reaction [Sarin results in decreased activity of BCHE protein]; Oximes analog inhibits the reaction [Sarin results in decreased activity of BCHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]; pralidoxime inhibits the reaction [Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]]; pralidoxime inhibits the reaction [Sarin analog results in decreased activity of BCHE protein]; Sarin analog inhibits the reaction [BCHE protein results in increased hydrolysis of Butyrylthiocholine]; Sarin analog promotes the reaction [Sarin binds to BCHE protein]
Physostigmine inhibits the reaction [Sarin results in decreased activity of BCHE protein]
BCHE protein results in decreased susceptibility to Sarin
Sarin results in increased phosphorylation of BCHE protein
Sarin results in decreased expression of BCHE mRNA
Sarin analog results in decreased activity of BCHE protein; Sarin metabolite results in decreased activity of BCHE protein; Sarin results in decreased activity of BCHE protein
CTD PMID:17698511 PMID:18617161 PMID:19283689 PMID:19428953 PMID:19522546 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
EXP Sarin results in increased expression of BCL2 mRNA
Sarin results in decreased expression of BCL2 protein
CTD PMID:27639427 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression
ISO Sarin results in decreased expression of BCL2L1 mRNA
Sarin results in increased expression of BCL2L1 mRNA
CTD PMID:19522546 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bex3 brain expressed X-linked 3 decreases expression ISO Sarin results in decreased expression of BEX3 mRNA CTD PMID:19522546 NCBI chr  X:99,273,238...99,274,799
Ensembl chr  X:99,273,161...99,274,800
JBrowse link
G Bptf bromodomain PHD finger transcription factor increases expression ISO Sarin results in increased expression of BPTF mRNA CTD PMID:19522546 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 decreases expression
increases expression
ISO Sarin results in decreased expression of CACNG4 mRNA
Sarin results in increased expression of CACNG4 mRNA
CTD PMID:19522546 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Calm1 calmodulin 1 increases expression
decreases expression
ISO Sarin results in increased expression of CALM1 mRNA
Sarin results in decreased expression of CALM1 mRNA
CTD PMID:19522546 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm3 calmodulin 3 decreases expression ISO Sarin results in decreased expression of CALM3 mRNA CTD PMID:19522546 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
JBrowse link
G Capn1 calpain 1 increases expression EXP Sarin results in increased expression of CAPN1 protein CTD PMID:21439362 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Casp4 caspase 4 increases expression ISO Sarin results in increased expression of CASP4 mRNA CTD PMID:19522546 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO Sarin results in increased expression of CCR1 mRNA CTD PMID:19522546 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd24 CD24 molecule decreases expression
increases expression
ISO Sarin results in decreased expression of CD24 mRNA
Sarin results in increased expression of CD24 mRNA
CTD PMID:19522546 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
JBrowse link
G Cd9 CD9 molecule decreases expression ISO Sarin results in decreased expression of CD9 mRNA; Sarin results in decreased expression of CD9 protein CTD PMID:19522546 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression
increases expression
ISO Sarin results in decreased expression of CDK5 mRNA
Sarin results in increased expression of CDK5 mRNA
CTD PMID:19522546 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 increases expression ISO Sarin results in increased expression of CEPT1 mRNA CTD PMID:19522546 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO CES1 protein affects the metabolism of and results in decreased activity of Sarin CTD PMID:12679808 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Sarin results in increased expression of CFLAR mRNA CTD PMID:19522546 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP Sarin results in decreased expression of CHAT protein CTD PMID:22640809 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects activity
decreases expression
multiple interactions
EXP Sarin affects the activity of CHRM2 protein
Sarin results in decreased expression of CHRM2 protein
Sarin inhibits the reaction [AFDX 384 binds to CHRM2 protein]
CTD PMID:21419149 PMID:29128314 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit decreases expression ISO Sarin results in decreased expression of CHRNA3 mRNA CTD PMID:19522546 NCBI chr 8:55,401,981...55,415,012
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit decreases expression ISO Sarin results in decreased expression of CHRNB1 mRNA CTD PMID:19522546 NCBI chr10:54,501,096...54,516,418
Ensembl chr10:54,501,093...54,516,345
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit decreases expression ISO Sarin results in decreased expression of CHRNB4 mRNA CTD PMID:19522546 NCBI chr 8:55,418,379...55,436,967
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression ISO Sarin results in increased expression of CHRNE mRNA CTD PMID:19522546 NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
JBrowse link
G Cklf chemokine-like factor decreases expression
increases expression
ISO Sarin results in decreased expression of CKLF mRNA
Sarin results in increased expression of CKLF mRNA
CTD PMID:19522546 NCBI chr19:698,097...706,570
Ensembl chr19:698,033...706,570
JBrowse link
G Clcn3 chloride voltage-gated channel 3 decreases expression ISO Sarin results in decreased expression of CLCN3 mRNA CTD PMID:19522546 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clns1a chloride nucleotide-sensitive channel 1A decreases expression ISO Sarin results in decreased expression of CLNS1A mRNA CTD PMID:19522546 NCBI chr 1:152,019,369...152,039,670
Ensembl chr 1:152,019,378...152,039,661
JBrowse link
G Clu clusterin decreases expression ISO Sarin results in decreased expression of CLU mRNA CTD PMID:19522546 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Sarin results in increased expression of CNR2 mRNA CTD PMID:19522546 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Sarin results in decreased expression of COL3A1 mRNA CTD PMID:19522546 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Coro1a coronin 1A decreases expression EXP Sarin results in decreased expression of CORO1A protein CTD PMID:28973502 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 decreases expression
increases expression
ISO Sarin results in decreased expression of COX15 mRNA
Sarin results in increased expression of COX15 mRNA
CTD PMID:19522546 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A decreases expression EXP Sarin results in decreased expression of COX5A protein CTD PMID:28973502 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression EXP Sarin results in decreased expression of COX5B protein CTD PMID:28973502 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 decreases expression
increases expression
ISO
EXP
Sarin results in decreased expression of COX6A1 mRNA
Sarin results in increased expression of COX6A1 protein
CTD PMID:19522546 PMID:28973502 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041
JBrowse link
G Cplx2 complexin 2 decreases expression EXP Sarin results in decreased expression of CPLX2 protein CTD PMID:28973502 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Creb3 cAMP responsive element binding protein 3 decreases expression ISO Sarin results in decreased expression of CREB3 mRNA CTD PMID:19522546 NCBI chr 5:57,817,835...57,823,171
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Cst3 cystatin C decreases expression ISO Sarin results in decreased expression of CST3 mRNA CTD PMID:19522546 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Cstb cystatin B decreases expression
increases expression
ISO Sarin results in decreased expression of CSTB mRNA
Sarin results in increased expression of CSTB mRNA
CTD PMID:19522546 NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
JBrowse link
G Ctsd cathepsin D decreases expression ISO Sarin results in decreased expression of CTSD mRNA CTD PMID:19522546 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cul4b cullin 4B decreases expression
increases expression
ISO Sarin results in decreased expression of CUL4B mRNA
Sarin results in increased expression of CUL4B mRNA
CTD PMID:19522546 NCBI chr  X:117,287,481...117,326,688
Ensembl chr  X:117,287,484...117,326,688
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Sarin results in decreased expression of CXCR4 mRNA CTD PMID:19522546 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyc1 cytochrome c-1 increases expression ISO Sarin results in increased expression of CYC1 mRNA CTD PMID:19522546 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Dag1 dystroglycan 1 decreases expression ISO Sarin results in decreased expression of DAG1 mRNA CTD PMID:19522546 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dbh dopamine beta-hydroxylase decreases expression ISO Sarin results in decreased expression of DBH mRNA CTD PMID:19522546 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dbn1 drebrin 1 decreases expression ISO Sarin results in decreased expression of DBN1 mRNA CTD PMID:19522546 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Dctn2 dynactin subunit 2 increases expression EXP Sarin results in increased expression of DCTN2 protein CTD PMID:28973502 NCBI chr 7:63,092,061...63,107,560
Ensembl chr 7:63,092,057...63,108,543
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 affects expression EXP Sarin affects the expression of DDAH1 protein CTD PMID:28973502 NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Sarin results in decreased expression of DDC mRNA; Sarin results in decreased expression of DDC protein CTD PMID:19522546 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Dguok deoxyguanosine kinase decreases expression
increases expression
ISO Sarin results in decreased expression of DGUOK mRNA
Sarin results in increased expression of DGUOK mRNA
CTD PMID:19522546 NCBI chr 4:115,987,101...116,014,733
Ensembl chr 4:115,979,094...116,014,733
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression EXP Sarin results in decreased expression of DLD protein CTD PMID:28973502 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression ISO Sarin results in decreased expression of DLK1 mRNA CTD PMID:19522546 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression EXP Sarin results in decreased expression of DLST protein CTD PMID:28973502 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 decreases expression
increases expression
ISO Sarin results in decreased expression of DNAJA1 mRNA
Sarin results in increased expression of DNAJA1 mRNA
CTD PMID:19522546 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 decreases expression ISO Sarin results in decreased expression of DNAJB2 mRNA CTD PMID:19522546 NCBI chr 9:76,731,060...76,739,278
Ensembl chr 9:76,731,065...76,739,277
JBrowse link
G Drd5 dopamine receptor D5 increases expression ISO Sarin results in increased expression of DRD5 mRNA CTD PMID:19522546 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression
increases expression
ISO Sarin results in decreased expression of DYNLL1 mRNA
Sarin results in increased expression of DYNLL1 mRNA
CTD PMID:19522546 NCBI chr12:41,312,367...41,314,742
Ensembl chr12:41,312,367...41,314,741
JBrowse link
G Efna4 ephrin A4 decreases expression ISO Sarin results in decreased expression of EFNA4 mRNA CTD PMID:19522546 NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979
JBrowse link
G Eid1 EP300 interacting inhibitor of differentiation 1 decreases expression
increases expression
ISO Sarin results in decreased expression of EID1 mRNA
Sarin results in increased expression of EID1 mRNA
CTD PMID:19522546 NCBI chr 3:112,922,961...112,924,680
Ensembl chr 3:112,922,668...112,924,752
JBrowse link
G Eif2b1 eukaryotic translation initiation factor 2B subunit alpha decreases expression ISO Sarin results in decreased expression of EIF2B1 mRNA CTD PMID:19522546 NCBI chr12:32,025,593...32,033,848
Ensembl chr12:32,025,557...32,046,601
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 decreases expression ISO Sarin results in decreased expression of ELP1 mRNA CTD PMID:19522546 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Eno1 enolase 1 decreases expression EXP Sarin results in decreased expression of ENO1 protein CTD PMID:28973502 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Eno2 enolase 2 decreases expression EXP Sarin results in decreased expression of ENO2 protein CTD PMID:28973502 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Entpd8 ectonucleoside triphosphate diphosphohydrolase 8 decreases expression ISO Sarin results in decreased expression of ENTPD8 mRNA CTD PMID:19522546 NCBI chr 3:7,885,277...7,895,517
Ensembl chr 3:7,889,909...7,895,296
JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression
increases expression
ISO Sarin results in decreased expression of ETFB mRNA
Sarin results in increased expression of ETFB mRNA
CTD PMID:19522546 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Sarin results in increased expression of ETS2 mRNA; Sarin results in increased expression of ETS2 protein CTD PMID:19522546 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G F12 coagulation factor XII decreases expression ISO Sarin results in decreased expression of F12 mRNA CTD PMID:19522546 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP Sarin results in decreased expression of FABP5 protein CTD PMID:28973502 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fbln1 fibulin 1 decreases expression ISO Sarin results in decreased expression of FBLN1 mRNA CTD PMID:19522546 NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia increases expression ISO Sarin results in increased expression of FCER1A mRNA CTD PMID:19522546 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression
increases expression
ISO Sarin results in decreased expression of FEV mRNA
Sarin results in increased expression of FEV mRNA
CTD PMID:19522546 NCBI chr 9:76,439,164...76,443,603
Ensembl chr 9:76,439,172...76,443,065
JBrowse link
G Fth1 ferritin heavy chain 1 decreases expression ISO Sarin results in decreased expression of FTH1 mRNA CTD PMID:19522546 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Gabarap GABA type A receptor-associated protein decreases expression
increases expression
ISO Sarin results in decreased expression of GABARAP mRNA
Sarin results in increased expression of GABARAP mRNA
CTD PMID:19522546 NCBI chr10:54,714,834...54,717,769
Ensembl chr10:54,714,198...54,717,765
JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor subunit gamma 3 increases expression ISO Sarin results in increased expression of GABRG3 mRNA CTD PMID:19522546 NCBI chr 1:107,627,450...108,247,483
Ensembl chr 1:107,627,390...108,246,763
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression ISO Sarin results in decreased expression of GABRR1 mRNA CTD PMID:19522546 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Sarin results in increased expression of GADD45A mRNA CTD PMID:19522546 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Sarin results in decreased expression of GAP43 mRNA CTD PMID:19522546 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Sarin results in increased expression of GC protein CTD PMID:26778279 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases expression ISO Sarin results in decreased expression of GCH1 mRNA CTD PMID:19522546 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression
ISO
EXP
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of GFAP protein
Sarin results in increased expression of GFAP protein
CTD PMID:23692952 PMID:27639427 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Glo1 glyoxalase 1 increases expression EXP Sarin results in increased expression of GLO1 protein CTD PMID:28973502 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Glra1 glycine receptor, alpha 1 increases expression ISO Sarin results in increased expression of GLRA1 mRNA CTD PMID:19522546 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Gls glutaminase decreases expression ISO Sarin results in decreased expression of GLS mRNA CTD PMID:19522546 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Glud1 glutamate dehydrogenase 1 decreases expression ISO Sarin results in decreased expression of GLUD1 mRNA CTD PMID:19522546 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Glul glutamate-ammonia ligase decreases expression
increases expression
ISO
EXP
Sarin results in decreased expression of GLUL mRNA
Sarin results in decreased expression of GLNS protein
Sarin results in increased expression of GLUL mRNA
CTD PMID:19522546 PMID:28973502 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gnas GNAS complex locus decreases expression ISO Sarin results in decreased expression of GNAS mRNA CTD PMID:19522546 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression ISO Sarin results in decreased expression of GPI mRNA CTD PMID:19522546 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpr27 G protein-coupled receptor 27 increases expression ISO Sarin results in increased expression of GPR27 mRNA CTD PMID:19522546 NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO Sarin results in increased expression of GRIK5 mRNA CTD PMID:19522546 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression ISO Sarin results in increased expression of GRIN2B mRNA CTD PMID:19522546 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression ISO Sarin results in decreased expression of GSTA4 mRNA CTD PMID:19522546 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression ISO Sarin results in increased expression of GSTM5 mRNA CTD PMID:19522546 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 decreases expression ISO Sarin results in decreased expression of GSTT2 mRNA CTD PMID:19522546 NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO Sarin results in decreased expression of GSTZ1 mRNA CTD PMID:19522546 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression ISO Sarin results in decreased expression of HADHA mRNA CTD PMID:19522546 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP Sarin results in decreased expression of HBA1 protein CTD PMID:28973502 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression EXP Sarin results in decreased expression of HINT1 protein CTD PMID:28973502 NCBI chr10:38,989,516...38,993,259 JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 increases expression ISO Sarin results in increased expression of HIPK2 mRNA CTD PMID:19522546 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression EXP Sarin results in decreased expression of HNRNPH1 protein CTD PMID:28973502 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846
JBrowse link
G Hp haptoglobin decreases expression EXP Sarin results in decreased expression of HP protein CTD PMID:26778279 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
JBrowse link
G Hpx hemopexin decreases expression EXP Sarin results in decreased expression of HPX protein CTD PMID:26778279 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 decreases expression
increases expression
ISO Sarin results in decreased expression of HSPA4 mRNA
Sarin results in increased expression of HSPA4 mRNA
CTD PMID:19522546 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression EXP Sarin results in decreased expression of HSPA8 protein CTD PMID:28973502 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 affects expression EXP Sarin affects the expression of HSPA9 protein CTD PMID:28973502 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression EXP Sarin affects the expression of HSPD1 protein CTD PMID:28973502 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Ids iduronate 2-sulfatase decreases expression ISO Sarin results in decreased expression of IDS mRNA CTD PMID:19522546 NCBI chr  X:149,025,977...149,046,639
Ensembl chr  X:149,025,976...149,046,663
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Sarin results in decreased expression of IFRD1 mRNA CTD PMID:19522546 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Il17rc interleukin 17 receptor C increases expression ISO Sarin results in increased expression of IL17RC mRNA CTD PMID:19522546 NCBI chr 4:146,618,321...146,631,444
Ensembl chr 4:146,619,004...146,631,442
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP
ISO
Sarin results in increased expression of IL1B mRNA; Sarin results in increased expression of IL1B protein
ezogabine inhibits the reaction [Sarin results in increased expression of IL1B protein]
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [[Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein]; [Sarin co-treated with 2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide] results in increased expression of IL1B protein
CTD PMID:17301067 PMID:23692952 PMID:32209366 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il22ra1 interleukin 22 receptor subunit alpha 1 increases expression ISO Sarin results in increased expression of IL22RA1 mRNA CTD PMID:19522546 NCBI chr 5:147,961,496...147,986,296
Ensembl chr 5:147,961,349...147,986,296
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha increases expression ISO Sarin results in increased expression of IL27RA mRNA CTD PMID:19522546 NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP Sarin results in increased expression of IL6 mRNA; Sarin results in increased expression of IL6 protein
ezogabine inhibits the reaction [Sarin results in increased expression of IL6 protein]
CTD PMID:17301067 PMID:32209366 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ilf2 interleukin enhancer binding factor 2 decreases expression
increases expression
ISO Sarin results in decreased expression of ILF2 mRNA
Sarin results in increased expression of ILF2 mRNA
CTD PMID:19522546 NCBI chr 2:175,951,002...175,971,193
Ensembl chr 2:175,952,186...175,971,337
JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha decreases expression EXP Sarin results in decreased expression of INA protein CTD PMID:28973502 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
JBrowse link
G Insig1 insulin induced gene 1 increases expression
decreases expression
ISO Sarin results in increased expression of INSIG1 mRNA
Sarin results in decreased expression of INSIG1 mRNA
CTD PMID:19522546 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 decreases expression ISO Sarin results in decreased expression of IQGAP1 mRNA CTD PMID:19522546 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755
JBrowse link
G Irf2 interferon regulatory factor 2 decreases expression ISO Sarin results in decreased expression of IRF2 mRNA CTD PMID:19522546 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
JBrowse link
G Itm2b integral membrane protein 2B decreases expression ISO Sarin results in decreased expression of ITM2B mRNA CTD PMID:19522546 NCBI chr15:48,545,998...48,568,904
Ensembl chr15:48,546,001...48,568,917
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 decreases expression ISO Sarin results in decreased expression of ITPR1 mRNA CTD PMID:19522546 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Kat5 lysine acetyltransferase 5 decreases expression ISO Sarin results in decreased expression of KAT5 mRNA CTD PMID:19522546 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression
increases expression
ISO Sarin results in decreased expression of KAT6B mRNA
Sarin results in increased expression of KAT6B mRNA
CTD PMID:19522546 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 decreases expression
increases expression
ISO Sarin results in decreased expression of KCNJ8 mRNA
Sarin results in increased expression of KCNJ8 mRNA
CTD PMID:19522546 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression ISO Sarin results in decreased expression of LAMP2 mRNA CTD PMID:19522546 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522
JBrowse link
G Lamtor2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 decreases expression ISO Sarin results in decreased expression of LAMTOR2 mRNA CTD PMID:19522546 NCBI chr 2:174,008,556...174,011,950
Ensembl chr 2:174,008,548...174,013,013
JBrowse link
G Lasp1 LIM and SH3 protein 1 decreases expression EXP Sarin results in decreased expression of LASP1 protein CTD PMID:28973502 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
JBrowse link
G Lin7c lin-7 homolog C, crumbs cell polarity complex component increases expression ISO Sarin results in increased expression of LIN7C mRNA CTD PMID:19522546 NCBI chr 3:96,406,825...96,414,137
Ensembl chr 3:96,406,813...96,417,728
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor decreases expression ISO Sarin results in decreased expression of LITAF mRNA CTD PMID:19522546 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
JBrowse link
G Lrp8 LDL receptor related protein 8 increases expression ISO Sarin results in increased expression of LRP8 mRNA CTD PMID:19522546 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP Sarin results in decreased expression of MAP2 protein CTD PMID:27639427 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO Sarin results in decreased expression of MAP2K2 mRNA CTD PMID:19522546 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Sarin results in decreased expression of MAPT mRNA CTD PMID:19522546 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Sarin results in decreased expression of MARCKS mRNA CTD PMID:19522546 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression
increases expression
ISO Sarin results in decreased expression of MCL1 mRNA
Sarin results in increased expression of MCL1 mRNA
CTD PMID:19522546 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression
increases expression
ISO Sarin results in decreased expression of MFAP4 mRNA
Sarin results in increased expression of MFAP4 mRNA
CTD PMID:19522546 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO Sarin results in decreased expression of MFN1 mRNA CTD PMID:19522546 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
JBrowse link
G Mif macrophage migration inhibitory factor increases expression EXP Sarin results in increased expression of MIF protein CTD PMID:28973502 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mpdu1 mannose-P-dolichol utilization defect 1 decreases expression ISO Sarin results in decreased expression of MPDU1 mRNA CTD PMID:19522546 NCBI chr10:54,374,719...54,380,301
Ensembl chr10:54,374,725...54,380,447
JBrowse link
G Mpzl1 myelin protein zero-like 1 decreases expression ISO Sarin results in decreased expression of MPZL1 mRNA CTD PMID:19522546 NCBI chr13:77,852,467...77,889,305
Ensembl chr13:77,852,467...77,896,616
JBrowse link
G Mrps28 mitochondrial ribosomal protein S28 decreases expression ISO Sarin results in decreased expression of MRPS28 mRNA CTD PMID:19522546 NCBI chr 2:92,855,557...92,858,805
Ensembl chr 2:92,820,606...92,951,284
JBrowse link
G Mtmr2 myotubularin related protein 2 decreases expression ISO Sarin results in decreased expression of MTMR2 mRNA CTD PMID:19522546 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Sarin results in increased expression of PZP protein CTD PMID:26778279 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Musk muscle associated receptor tyrosine kinase increases expression ISO Sarin results in increased expression of MUSK mRNA CTD PMID:19522546 NCBI chr 5:73,058,427...73,169,696
Ensembl chr 5:73,058,121...73,171,932
JBrowse link
G Naca nascent polypeptide associated complex subunit alpha decreases expression ISO Sarin results in decreased expression of NACA mRNA CTD PMID:19522546 NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992
JBrowse link
G Napg NSF attachment protein gamma decreases expression EXP Sarin results in decreased expression of NAPG protein CTD PMID:28973502 NCBI chr18:56,439,620...56,459,159
Ensembl chr18:56,440,505...56,459,153
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 decreases expression ISO Sarin results in decreased expression of NCOR1 mRNA CTD PMID:19522546 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 decreases expression ISO Sarin results in decreased expression of NDUFS4 mRNA CTD PMID:19522546 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
JBrowse link
G Nefh neurofilament heavy chain increases phosphorylation EXP Sarin results in increased phosphorylation of NEFH protein CTD PMID:21439362 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects localization EXP Sarin affects the localization of NFKB1 protein CTD PMID:17301067 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Ngrn neugrin, neurite outgrowth associated decreases expression ISO Sarin results in decreased expression of NGRN mRNA CTD PMID:19522546 NCBI chr 1:134,213,235...134,219,348
Ensembl chr 1:134,213,456...134,219,339
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 decreases expression EXP Sarin results in decreased expression of NME1 protein CTD PMID:28973502 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Sarin affects the expression of NME2 protein CTD PMID:28973502 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nmu neuromedin U decreases expression ISO Sarin results in decreased expression of NMU mRNA CTD PMID:19522546 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192
JBrowse link
G Nosip nitric oxide synthase interacting protein increases expression ISO Sarin results in increased expression of NOSIP mRNA CTD PMID:19522546 NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650
JBrowse link
G Notch2 notch receptor 2 decreases expression ISO Sarin results in decreased expression of NOTCH2 mRNA CTD PMID:19522546 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Sarin results in decreased expression of NQO1 mRNA CTD PMID:19522546 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 decreases expression ISO Sarin results in decreased expression of NQO2 mRNA CTD PMID:19522546 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO Sarin results in decreased expression of NRCAM mRNA CTD PMID:19522546 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrp1 neuropilin 1 decreases expression
increases expression
ISO Sarin results in decreased expression of NRP1 mRNA
Sarin results in increased expression of NRP1 mRNA
CTD PMID:19522546 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Sarin results in increased expression of NTRK2 mRNA CTD PMID:19522546 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO Sarin results in increased expression of NTRK3 mRNA CTD PMID:19522546 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 decreases expression
increases expression
ISO Sarin results in decreased expression of OLR1 mRNA
Sarin results in increased expression of OLR1 mRNA
CTD PMID:19522546 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Osmr oncostatin M receptor increases expression ISO Sarin results in increased expression of OSMR mRNA CTD PMID:19522546 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta decreases expression ISO Sarin results in decreased expression of P4HB mRNA CTD PMID:19522546 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pank3 pantothenate kinase 3 decreases expression ISO Sarin results in decreased expression of PANK3 mRNA CTD PMID:19522546 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
JBrowse link
G Park7 Parkinsonism associated deglycase decreases expression ISO
EXP
Sarin results in decreased expression of PARK7 mRNA
Sarin results in decreased expression of PARK7 protein
CTD PMID:19522546 PMID:28973502 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parl presenilin associated, rhomboid-like decreases expression ISO Sarin results in decreased expression of PARL mRNA CTD PMID:19522546 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Sarin results in decreased expression of PCMT1 mRNA CTD PMID:19522546 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta decreases expression
increases expression
ISO
EXP
Sarin results in decreased expression of PDHB mRNA
Sarin results in decreased expression of PDHB protein
Sarin results in increased expression of PDHB mRNA
CTD PMID:19522546 PMID:28973502 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Sarin affects the expression of PDIA3 protein CTD PMID:28973502 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase decreases expression ISO Sarin results in decreased expression of PEMT mRNA CTD PMID:19522546 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Pepd peptidase D increases hydrolysis ISO PEPD protein results in increased hydrolysis of Sarin CTD PMID:20176006 PMID:22120822 PMID:22677456 NCBI chr 1:87,536,650...87,681,233 JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression ISO Sarin results in decreased expression of PFKP mRNA CTD PMID:19522546 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pfn2 profilin 2 decreases expression EXP Sarin results in decreased expression of PFN2 protein CTD PMID:28973502 NCBI chr 2:142,067,102...142,072,938
Ensembl chr 2:142,067,104...142,072,938
JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression
increases expression
ISO Sarin results in decreased expression of PLA2G5 mRNA
Sarin results in increased expression of PLA2G5 mRNA
CTD PMID:19522546 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
JBrowse link
G Pla2g6 phospholipase A2 group VI increases expression ISO Sarin results in increased expression of PLA2G6 mRNA CTD PMID:19522546 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Plaa phospholipase A2, activating protein increases expression ISO Sarin results in increased expression of PLAA mRNA CTD PMID:19522546 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
JBrowse link
G Pltp phospholipid transfer protein decreases expression ISO Sarin results in decreased expression of PLTP mRNA CTD PMID:19522546 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression ISO Sarin results in decreased expression of PMP22 mRNA CTD PMID:19522546 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Pnma1 PNMA family member 1 decreases expression
increases expression
ISO Sarin results in decreased expression of PNMA1 mRNA
Sarin results in increased expression of PNMA1 mRNA
CTD PMID:19522546 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity ISO Sarin results in decreased activity of PNPLA6 protein CTD PMID:8486913 NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Pomc proopiomelanocortin decreases expression EXP Sarin results in decreased expression of POMC protein CTD PMID:17301067 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
increases hydrolysis
decreases response to substance
ISO PON1 protein inhibits the reaction [Sarin results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Sarin results in decreased activity of BCHE protein]
PON1 protein mutant form results in increased hydrolysis of Sarin; PON1 protein results in increased hydrolysis of Sarin
PON1 protein mutant form results in decreased susceptibility to Sarin
CTD PMID:16331452 PMID:20176006 PMID:21329748 PMID:23159884 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression
increases expression
ISO Sarin results in decreased expression of POR mRNA
Sarin results in increased expression of POR mRNA
CTD PMID:19522546 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO Sarin results in decreased expression of PPP1CA mRNA CTD PMID:19522546 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 decreases expression ISO Sarin results in decreased expression of PPT1 mRNA CTD PMID:19522546 NCBI chr 5:135,121,176...135,141,076
Ensembl chr 5:135,121,163...135,142,048
JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression EXP Sarin results in decreased expression of PRDX6 protein CTD PMID:28973502 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO Sarin results in increased expression of PRKCB mRNA CTD PMID:19522546 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prss12 serine protease 12 decreases expression ISO Sarin results in decreased expression of PRSS12 mRNA CTD PMID:19522546 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126
JBrowse link
G Psen1 presenilin 1 decreases expression ISO Sarin results in decreased expression of PSEN1 mRNA; Sarin results in decreased expression of PSEN1 protein CTD PMID:19522546 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psen2 presenilin 2 decreases expression ISO Sarin results in decreased expression of PSEN2 mRNA CTD PMID:19522546 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Psma1 proteasome 20S subunit alpha 1 increases expression EXP Sarin results in increased expression of PSMA1 protein CTD PMID:28973502 NCBI chr 1:168,442,421...168,453,440
Ensembl chr 1:168,440,936...168,453,472
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression
increases expression
ISO Sarin results in decreased expression of PSMA3 mRNA
Sarin results in increased expression of PSMA3 mRNA
CTD PMID:19522546 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
JBrowse link
G Psmd8 proteasome 26S subunit, non-ATPase 8 decreases expression ISO Sarin results in decreased expression of PSMD8 mRNA CTD PMID:19522546 NCBI chr 1:84,474,377...84,481,209
Ensembl chr 1:84,474,378...84,481,209
JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R decreases expression ISO Sarin results in decreased expression of PTPRR mRNA CTD PMID:19522546 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603
JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase decreases expression ISO Sarin results in decreased expression of PTS mRNA CTD PMID:19522546 NCBI chr 8:50,870,838...50,877,878
Ensembl chr 8:50,870,841...50,877,869
JBrowse link
G Pura purine rich element binding protein A affects expression EXP Sarin affects the expression of PURA protein CTD PMID:28973502
G Ranbp1 RAN binding protein 1 decreases expression ISO Sarin results in decreased expression of RANBP1 mRNA CTD PMID:19522546 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 increases expression ISO Sarin results in increased expression of RASGRP2 mRNA CTD PMID:19522546 NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993
JBrowse link
G Rfxank regulatory factor X-associated ankyrin-containing protein decreases expression ISO Sarin results in decreased expression of RFXANK mRNA CTD PMID:19522546 NCBI chr16:19,280,857...19,288,886
Ensembl chr16:19,281,475...19,460,255
JBrowse link
G Rgn regucalcin increases hydrolysis ISO RGN protein results in increased hydrolysis of Sarin CTD PMID:20176006 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Sarin results in decreased expression of RGS4 mRNA CTD PMID:19522546 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068
JBrowse link
G Rtn3 reticulon 3 decreases expression ISO Sarin results in decreased expression of RTN3 mRNA CTD PMID:19522546 NCBI chr 1:204,612,675...204,669,212
Ensembl chr 1:204,612,675...204,669,275
JBrowse link
G Scarb2 scavenger receptor class B, member 2 decreases expression ISO Sarin results in decreased expression of SCARB2 mRNA CTD PMID:19522546 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression
increases expression
ISO Sarin results in decreased expression of SCD mRNA
Sarin results in increased expression of SCD mRNA
CTD PMID:19522546 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 increases expression ISO Sarin results in increased expression of SCN10A mRNA CTD PMID:19522546 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Sdcbp syndecan binding protein decreases expression ISO Sarin results in decreased expression of SDCBP mRNA CTD PMID:19522546 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572
JBrowse link
G Septin5 septin 5 increases expression EXP Sarin results in increased expression of SEPTIN5 protein CTD PMID:28973502 NCBI chr11:82,373,601...82,379,393
Ensembl chr11:82,369,754...82,379,393
JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO Sarin results in decreased expression of SERPINI1 mRNA CTD PMID:19522546 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression ISO Sarin results in decreased expression of SGK1 mRNA CTD PMID:19522546 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 decreases expression EXP Sarin results in decreased expression of SH3GL1 protein CTD PMID:28973502 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716
JBrowse link
G Slc18a3 solute carrier family 18 member A3 decreases expression EXP Sarin results in decreased expression of SLC18A3 protein CTD PMID:22640809 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Slc20a1 solute carrier family 20 member 1 decreases expression ISO Sarin results in decreased expression of SLC20A1 mRNA CTD PMID:19522546 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
JBrowse link
G Slc6a15 solute carrier family 6 member 15 decreases expression ISO Sarin results in decreased expression of SLC6A15 mRNA CTD PMID:19522546 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239
JBrowse link
G Snca synuclein alpha decreases expression ISO
EXP
Sarin results in decreased expression of SNCA mRNA
Sarin results in decreased expression of SNCA protein
CTD PMID:19522546 PMID:28973502 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Socs5 suppressor of cytokine signaling 5 decreases expression
increases expression
ISO Sarin results in decreased expression of SOCS5 mRNA
Sarin results in increased expression of SOCS5 mRNA
CTD PMID:19522546 NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP Sarin results in decreased expression of SOD1 protein CTD PMID:28973502 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Spast spastin decreases expression ISO Sarin results in decreased expression of SPG4 mRNA CTD PMID:19522546 NCBI chr 6:21,055,349...21,106,586
Ensembl chr 6:21,055,349...21,107,954
JBrowse link
G Stip1 stress-induced phosphoprotein 1 affects expression EXP Sarin affects the expression of STIP1 protein CTD PMID:28973502 NCBI chr 1:204,209,434...204,228,452
Ensembl chr 1:204,178,932...204,228,476
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Sarin results in decreased expression of STMN1 protein CTD PMID:28973502 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stmn2 stathmin 2 decreases expression ISO Sarin results in decreased expression of STMN2 mRNA CTD PMID:19522546 NCBI chr 2:93,204,690...93,252,011
Ensembl chr 2:93,204,692...93,252,011
JBrowse link
G Stx4 syntaxin 4 decreases expression ISO Sarin results in decreased expression of STX4A mRNA CTD PMID:19522546 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
JBrowse link
G Syt1 synaptotagmin 1 increases expression ISO Sarin results in increased expression of SYT1 mRNA CTD PMID:19522546 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
G Tagln3 transgelin 3 increases expression EXP Sarin results in increased expression of TAGLN3 protein CTD PMID:28973502 NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485
JBrowse link
G Tbcc tubulin folding cofactor C decreases expression
increases expression
ISO Sarin results in decreased expression of TBCC mRNA
Sarin results in increased expression of TBCC mRNA
CTD PMID:19522546 NCBI chr 9:14,098,875...14,100,026
Ensembl chr 9:14,098,868...14,100,042
JBrowse link
G Tcfl5 transcription factor like 5 decreases expression ISO Sarin results in decreased expression of TCFL5 mRNA CTD PMID:19522546 NCBI chr 3:167,734,471...167,754,174
Ensembl chr 3:167,734,473...167,754,282
JBrowse link
G Tf transferrin affects binding ISO Sarin binds to TF protein
Sarin binds to TRF protein
CTD PMID:18930948 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfrc transferrin receptor decreases expression ISO Sarin results in decreased expression of TFRC mRNA CTD PMID:19522546 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tm2d1 TM2 domain containing 1 increases expression ISO Sarin results in increased expression of TM2D1 mRNA CTD PMID:19522546 NCBI chr 5:113,020,760...113,062,370
Ensembl chr 5:113,020,760...113,050,933
JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 decreases expression ISO Sarin results in decreased expression of TMED10 mRNA CTD PMID:19522546 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753
JBrowse link
G Tmsb15b2 thymosin beta 15B2 decreases expression ISO Sarin results in decreased expression of TMSB15A mRNA CTD PMID:19522546 NCBI chr  X:100,298,705...100,300,820
Ensembl chr  X:100,298,514...100,300,886
JBrowse link
G Tnf tumor necrosis factor increases expression EXP Sarin results in increased expression of TNF mRNA CTD PMID:17301067 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Sarin results in increased expression of TNFRSF9 mRNA CTD PMID:19522546 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO Sarin results in decreased expression of TOP2A mRNA CTD PMID:19522546 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tpi1 triosephosphate isomerase 1 affects expression EXP Sarin affects the expression of TPI1 protein CTD PMID:28973502 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tpm1 tropomyosin 1 decreases expression ISO Sarin results in decreased expression of TPM1 mRNA CTD PMID:19522546 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Traf5 TNF receptor-associated factor 5 increases expression ISO Sarin results in increased expression of TRAF5 mRNA CTD PMID:19522546 NCBI chr13:103,569,944...103,618,756
Ensembl chr13:103,572,314...103,618,709
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 increases expression ISO Sarin results in increased expression of TRPM3 mRNA CTD PMID:19522546 NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
JBrowse link
G Tspan3 tetraspanin 3 decreases expression ISO Sarin results in decreased expression of TSPAN3 mRNA CTD PMID:19522546 NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880
JBrowse link
G Tspo translocator protein increases expression
multiple interactions
EXP Sarin results in increased expression of TSPO mRNA; Sarin results in increased expression of TSPO protein
ezogabine inhibits the reaction [Sarin results in increased expression of TSPO protein]
CTD PMID:27639427 PMID:32209366 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
JBrowse link
G Tubb2b tubulin, beta 2B class IIb decreases expression EXP Sarin results in decreased expression of TUBB2B protein CTD PMID:28973502 NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression EXP Sarin results in decreased expression of TUBB3 protein CTD PMID:28973502 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression ISO Sarin results in decreased expression of TUBG1 mRNA CTD PMID:19522546 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433
JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 decreases expression ISO Sarin results in decreased expression of UBE2G1 mRNA CTD PMID:19522546 NCBI chr10:57,225,963...57,306,748
Ensembl chr10:57,225,952...57,308,568
JBrowse link
G Ube2m ubiquitin-conjugating enzyme E2M decreases expression ISO Sarin results in decreased expression of UBE2M mRNA CTD PMID:19522546 NCBI chr 1:73,662,576...73,666,113
Ensembl chr 1:73,662,576...73,666,026
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 affects expression EXP Sarin affects the expression of UCHL1 protein CTD PMID:28973502 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 decreases expression ISO Sarin results in decreased expression of UCHL3 mRNA CTD PMID:19522546 NCBI chr15:78,485,304...78,527,355
Ensembl chr15:78,485,315...78,527,355
JBrowse link
G Usp14 ubiquitin specific peptidase 14 decreases expression ISO Sarin results in decreased expression of USP14 mRNA CTD PMID:19522546 NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 decreases expression ISO Sarin results in decreased expression of VAMP3 mRNA CTD PMID:19522546 NCBI chr 5:161,498,109...161,508,704
Ensembl chr 5:161,498,109...161,508,751
JBrowse link
G Vdac1 voltage-dependent anion channel 1 increases expression ISO Sarin results in increased expression of VDAC1 mRNA CTD PMID:19522546 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression
increases expression
ISO Sarin results in decreased expression of YWHAB mRNA
Sarin results in increased expression of YWHAB mRNA
CTD PMID:19522546 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon decreases expression ISO Sarin results in decreased expression of YWHAE mRNA CTD PMID:19522546 NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 decreases expression ISO Sarin results in decreased expression of ZEB1 mRNA CTD PMID:19522546 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214
JBrowse link
G Zfp532 zinc finger protein 532 decreases expression ISO Sarin results in decreased expression of ZNF532 mRNA CTD PMID:19522546 NCBI chr18:59,080,082...59,203,672
Ensembl chr18:59,092,789...59,203,666
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        aetiopathogenetic role 19044
          neurotoxin 17842
            (S)-sarin 289
              sarin 289
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organochalcogen compound 19064
                                organooxygen compound 19014
                                  ester 16733
                                    phosphinic ester 317
                                      isopropyl methylphosphonofluoridate 289
                                        (S)-sarin 289
                                          sarin 289
paths to the root