ALDOC (aldolase, fructose-bisphosphate C) - Rat Genome Database

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Advanced Search (OLGA)
Gene: ALDOC (aldolase, fructose-bisphosphate C) Homo sapiens
Analyze
Symbol: ALDOC
Name: aldolase, fructose-bisphosphate C
RGD ID: 69125
HGNC Page HGNC:418
Description: Enables cytoskeletal protein binding activity and fructose-bisphosphate aldolase activity. Involved in epithelial cell differentiation and fructose 1,6-bisphosphate metabolic process. Located in extracellular exosome. Implicated in autoimmune disease of the nervous system.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ALDC; aldolase 3; aldolase c, fructose-biphosphate; aldolase C, fructose-bisphosphate; brain-type aldolase; fructoaldolase C; fructose-1,6-biphosphate triosephosphate lyase; fructose-bisphosphate aldolase C
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,573,120 - 28,576,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,573,115 - 28,576,948 (-)EnsemblGRCh38hg38GRCh38
GRCh371726,900,138 - 26,903,913 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,924,260 - 23,928,078 (-)NCBINCBI36Build 36hg18NCBI36
Build 341723,924,265 - 23,927,989NCBI
Celera1723,759,160 - 23,762,978 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,108,999 - 23,112,817 (-)NCBIHuRef
CHM1_11726,961,834 - 26,965,652 (-)NCBICHM1_1
T2T-CHM13v2.01729,515,745 - 29,519,520 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+/-)-Aegeline  (ISO)
(-)-alpha-phellandrene  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(1->4)-beta-D-glucan  (ISO)
(RS)-coclaurine  (ISO)
(RS)-norcoclaurine  (ISO)
(S)-coclaurine  (ISO)
1,10-phenanthroline  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dimethoxyphenol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
aconitine  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (EXP)
alpha-phellandrene  (EXP)
ammonium chloride  (ISO)
Archazolid B  (EXP)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (EXP)
Bisphenol B  (EXP)
bisphenol F  (EXP,ISO)
bleomycin A2  (ISO)
butan-1-ol  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (EXP,ISO)
cannabidiol  (EXP,ISO)
captan  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
cisplatin  (EXP,ISO)
clozapine  (ISO)
cobalt dichloride  (EXP)
copper(II) chloride  (EXP,ISO)
CU-O LINKAGE  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
diclofenac  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethylarsinic acid  (ISO)
dinophysistoxin 1  (EXP)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP)
dizocilpine maleate  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (EXP)
etoposide  (EXP,ISO)
Evodiamine  (ISO)
fenthion  (ISO)
flavonoids  (ISO)
fluoxetine  (EXP)
flutamide  (ISO)
folpet  (ISO)
fructose  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
furfural  (EXP)
genistein  (ISO)
glucose  (ISO)
haloperidol  (ISO)
herbicide  (ISO)
hydroxyurea  (ISO)
indometacin  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
isobutanol  (EXP)
ivermectin  (EXP)
ketamine  (ISO)
lead diacetate  (EXP,ISO)
Macrosphelide A  (EXP)
maneb  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (ISO)
methidathion  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (EXP)
methylarsonic acid  (ISO)
methylparaben  (EXP)
mifepristone  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (EXP)
nickel dichloride  (ISO)
nickel sulfate  (EXP)
niclosamide  (EXP)
nitrates  (ISO)
NMN zwitterion  (ISO)
obeticholic acid  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorobutyric acid  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (EXP)
phenylpropanolamine  (ISO)
picoxystrobin  (EXP)
pirinixic acid  (ISO)
potassium chromate  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
quercetin  (EXP)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
sarin  (ISO)
SB 431542  (EXP)
silicon dioxide  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
SKF 38393  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
Soman  (ISO)
sotorasib  (EXP)
sulindac sulfide  (EXP)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tapentadol  (EXP)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
theophylline  (EXP)
thimerosal  (EXP)
thioacetamide  (ISO)
thiram  (EXP)
titanium dioxide  (ISO)
trametinib  (EXP)
triclosan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
tunicamycin  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vincristine  (EXP)
vorinostat  (EXP)
Yessotoxin  (EXP)
yohimbine  (ISO)
zearalenone  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease. Dale RC, etal., J Neuroimmunol. 2006 Mar;172(1-2):187-97. Epub 2005 Dec 13.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Aldolase C/zebrin II is released to the extracellular space after stroke and inhibits the network activity of cortical neurons. Linke S, etal., Neurochem Res. 2006 Nov;31(11):1297-303. Epub 2006 Oct 20.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. The complete amino acid sequence of the human aldolase C isozyme derived from genomic clones. Rottmann WH, etal., Biochimie 1987 Feb;69(2):137-45.
8. Molecular cloning and expression of rat aldolase C messenger RNA during development and hepatocarcinogenesis. Skala H, etal., Eur J Biochem. 1987 Mar 16;163(3):513-8.
9. Spatiotemporal analysis of purkinje cell degeneration relative to parasagittal expression domains in a model of neonatal viral infection. Williams BL, etal., J Virol. 2007 Mar;81(6):2675-87. Epub 2006 Dec 20.
Additional References at PubMed
PMID:2209624   PMID:2731939   PMID:3267224   PMID:3674018   PMID:5230152   PMID:6696436   PMID:8619474   PMID:9110174   PMID:9244396   PMID:11399750   PMID:11876650   PMID:12477932  
PMID:15489334   PMID:15537755   PMID:15589842   PMID:16196087   PMID:16916647   PMID:17500595   PMID:19034380   PMID:19056867   PMID:19110265   PMID:19405953   PMID:19686046   PMID:20381070  
PMID:20458337   PMID:21139048   PMID:21145461   PMID:21492153   PMID:21653829   PMID:21873635   PMID:21890473   PMID:21906983   PMID:21963094   PMID:21987572   PMID:21988832   PMID:22053931  
PMID:22505724   PMID:22658674   PMID:22863883   PMID:22939629   PMID:23000965   PMID:23376485   PMID:23533145   PMID:23824909   PMID:23874603   PMID:24163370   PMID:24525694   PMID:24816145  
PMID:24993527   PMID:24999758   PMID:25416956   PMID:25798074   PMID:25910212   PMID:25921289   PMID:25963833   PMID:26186194   PMID:26344197   PMID:26496610   PMID:28443643   PMID:28514442  
PMID:28524877   PMID:29507755   PMID:29564676   PMID:29845934   PMID:29872149   PMID:29924966   PMID:30097533   PMID:30396920   PMID:30397336   PMID:30575818   PMID:30884312   PMID:30948266  
PMID:31067453   PMID:31409639   PMID:31515488   PMID:31536960   PMID:31586073   PMID:31980649   PMID:32235678   PMID:32296183   PMID:32502493   PMID:32963011   PMID:33242559   PMID:33274599  
PMID:33664453   PMID:33916271   PMID:33961781   PMID:34349018   PMID:34456184   PMID:35012549   PMID:35063084   PMID:35147255   PMID:35156780   PMID:35235311   PMID:35271311   PMID:35384245  
PMID:35446349   PMID:35777956   PMID:35831314   PMID:35918402   PMID:35944360   PMID:36012204   PMID:36114006   PMID:36215168   PMID:36217030   PMID:36652389   PMID:36945054   PMID:36997056  
PMID:37031206   PMID:37071682   PMID:37164154   PMID:38334954   PMID:39358380  


Genomics

Comparative Map Data
ALDOC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,573,120 - 28,576,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,573,115 - 28,576,948 (-)EnsemblGRCh38hg38GRCh38
GRCh371726,900,138 - 26,903,913 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,924,260 - 23,928,078 (-)NCBINCBI36Build 36hg18NCBI36
Build 341723,924,265 - 23,927,989NCBI
Celera1723,759,160 - 23,762,978 (-)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,108,999 - 23,112,817 (-)NCBIHuRef
CHM1_11726,961,834 - 26,965,652 (-)NCBICHM1_1
T2T-CHM13v2.01729,515,745 - 29,519,520 (-)NCBIT2T-CHM13v2.0
Aldoc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,213,899 - 78,218,607 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,213,794 - 78,218,607 (+)EnsemblGRCm39 Ensembl
GRCm381178,323,073 - 78,327,781 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,322,968 - 78,327,781 (+)EnsemblGRCm38mm10GRCm38
MGSCv371178,137,700 - 78,140,262 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361178,140,393 - 78,142,955 (+)NCBIMGSCv36mm8
Celera1187,956,279 - 87,958,841 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Aldoc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,715,544 - 63,719,133 (+)NCBIGRCr8
mRatBN7.21063,217,477 - 63,221,066 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,217,451 - 63,221,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,849,778 - 67,853,367 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,355,127 - 67,358,716 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,826,255 - 62,829,844 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,586,504 - 65,590,093 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,586,504 - 65,590,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,049,065 - 66,052,654 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,308,826 - 64,312,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11064,322,448 - 64,326,038 (-)NCBI
Celera1062,195,147 - 62,198,736 (+)NCBICelera
Cytogenetic Map10q25NCBI
Aldoc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,576,913 - 4,580,999 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,576,913 - 4,580,999 (+)NCBIChiLan1.0ChiLan1.0
ALDOC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21935,883,364 - 35,887,202 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11737,763,485 - 37,767,324 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01728,198,895 - 28,202,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,702,447 - 28,706,507 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,700,976 - 28,706,507 (+)Ensemblpanpan1.1panPan2
ALDOC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,778,637 - 42,782,950 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,778,637 - 42,782,479 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,935,297 - 41,939,139 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,597,372 - 43,601,698 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,597,399 - 43,601,698 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,380,447 - 42,384,288 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,673,144 - 42,676,986 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,750,567 - 42,754,409 (-)NCBIUU_Cfam_GSD_1.0
Aldoc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,921,047 - 41,924,788 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365384,798,989 - 4,802,994 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365384,798,991 - 4,802,700 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALDOC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,822,780 - 44,827,597 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,823,376 - 44,827,273 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,807,780 - 46,811,676 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALDOC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,342,750 - 22,346,811 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1622,341,318 - 22,346,620 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660757,779,923 - 7,784,075 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Aldoc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,158,248 - 1,162,916 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247861,158,270 - 1,162,801 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ALDOC
25 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q11.2(chr17:28283125-28904397)x3 copy number gain See cases [RCV000136494] Chr17:28283125..28904397 [GRCh38]
Chr17:26610151..27231415 [GRCh37]
Chr17:23634278..24255541 [NCBI36]
Chr17:17q11.2		 benign
GRCh37/hg19 17q11.1-11.2(chr17:25403446-31685464)x3 copy number gain not provided [RCV000762776] Chr17:25403446..31685464 [GRCh37]
Chr17:17q11.1-11.2		 likely pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17q11.1-11.2(chr17:25248166-30645676)x1 copy number loss Mitogen-activated protein kinase kinase inhibitor response [RCV000626439] Chr17:25248166..30645676 [GRCh37]
Chr17:17q11.1-11.2		 drug response
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3		 pathogenic
GRCh37/hg19 17p11.2-q11.2(chr17:21279289-27474974)x2 copy number gain not provided [RCV000739439] Chr17:21279289..27474974 [GRCh37]
Chr17:17p11.2-q11.2		 likely pathogenic
NM_005165.3(ALDOC):c.952C>A (p.Arg318=) single nucleotide variant not provided [RCV000930404] Chr17:28573782 [GRCh38]
Chr17:26900800 [GRCh37]
Chr17:17q11.2		 likely benign
GRCh37/hg19 17p11.2-q21.2(chr17:21690653-38772647)x3 copy number gain not provided [RCV000846852] Chr17:21690653..38772647 [GRCh37]
Chr17:17p11.2-q21.2		 pathogenic
GRCh37/hg19 17q11.1-11.2(chr17:25274363-28450707)x3 copy number gain not provided [RCV001006886] Chr17:25274363..28450707 [GRCh37]
Chr17:17q11.1-11.2		 pathogenic
GRCh37/hg19 17p11.2-q11.2(chr17:21690653-28281232) copy number gain not specified [RCV002052591] Chr17:21690653..28281232 [GRCh37]
Chr17:17p11.2-q11.2		 pathogenic
NC_000017.10:g.(?_26684694)_(27581367_?)dup duplication not provided [RCV003116316] Chr17:26684694..27581367 [GRCh37]
Chr17:17q11.2		 uncertain significance
NC_000017.10:g.(?_26684694)_(29701173_?)dup duplication not provided [RCV003123018] Chr17:26684694..29701173 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.506A>G (p.Asn169Ser) single nucleotide variant not specified [RCV004163675] Chr17:28574730 [GRCh38]
Chr17:26901748 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.229G>A (p.Val77Ile) single nucleotide variant not specified [RCV004192108] Chr17:28575218 [GRCh38]
Chr17:26902236 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.55A>G (p.Ile19Val) single nucleotide variant not specified [RCV004129841] Chr17:28575478 [GRCh38]
Chr17:26902496 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.707C>T (p.Pro236Leu) single nucleotide variant not specified [RCV004171591] Chr17:28574159 [GRCh38]
Chr17:26901177 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.517C>T (p.Arg173Cys) single nucleotide variant not specified [RCV004077486] Chr17:28574719 [GRCh38]
Chr17:26901737 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.445C>T (p.Arg149Cys) single nucleotide variant not specified [RCV004185474] Chr17:28574791 [GRCh38]
Chr17:26901809 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.287G>A (p.Arg96Gln) single nucleotide variant not specified [RCV004072454] Chr17:28575160 [GRCh38]
Chr17:26902178 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.343C>G (p.Pro115Ala) single nucleotide variant not specified [RCV004201671] Chr17:28574988 [GRCh38]
Chr17:26902006 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.911G>A (p.Arg304His) single nucleotide variant not specified [RCV004163496] Chr17:28573823 [GRCh38]
Chr17:26900841 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.726C>G (p.Ile242Met) single nucleotide variant not specified [RCV004173642] Chr17:28574140 [GRCh38]
Chr17:26901158 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.77C>T (p.Pro26Leu) single nucleotide variant not specified [RCV004280053] Chr17:28575456 [GRCh38]
Chr17:26902474 [GRCh37]
Chr17:17q11.2		 uncertain significance
GRCh37/hg19 17q11.1-11.2(chr17:25263507-27829791)x3 copy number gain Developmental delay with or without intellectual impairment or behavioral abnormalities [RCV003329553] Chr17:25263507..27829791 [GRCh37]
Chr17:17q11.1-11.2		 uncertain significance
NM_005165.3(ALDOC):c.599A>G (p.Lys200Arg) single nucleotide variant not specified [RCV004348301] Chr17:28574519 [GRCh38]
Chr17:26901537 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.7C>A (p.His3Asn) single nucleotide variant not specified [RCV004365459] Chr17:28575526 [GRCh38]
Chr17:26902544 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.469C>T (p.Arg157Cys) single nucleotide variant not specified [RCV004400781] Chr17:28574767 [GRCh38]
Chr17:26901785 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.602G>A (p.Arg201His) single nucleotide variant not specified [RCV004400800] Chr17:28574516 [GRCh38]
Chr17:26901534 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.613G>A (p.Val205Ile) single nucleotide variant not specified [RCV004400803] Chr17:28574505 [GRCh38]
Chr17:26901523 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.407C>A (p.Ala136Asp) single nucleotide variant not specified [RCV004400773] Chr17:28574829 [GRCh38]
Chr17:26901847 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.476C>T (p.Pro159Leu) single nucleotide variant not specified [RCV004400787] Chr17:28574760 [GRCh38]
Chr17:26901778 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.776G>A (p.Arg259His) single nucleotide variant not specified [RCV004400813] Chr17:28574090 [GRCh38]
Chr17:26901108 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.890C>T (p.Ala297Val) single nucleotide variant not specified [RCV004400818] Chr17:28573844 [GRCh38]
Chr17:26900862 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.17C>T (p.Pro6Leu) single nucleotide variant not specified [RCV004630247] Chr17:28575516 [GRCh38]
Chr17:26902534 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.508G>A (p.Val170Met) single nucleotide variant not specified [RCV004630229] Chr17:28574728 [GRCh38]
Chr17:26901746 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.235T>G (p.Phe79Val) single nucleotide variant not specified [RCV004630237] Chr17:28575212 [GRCh38]
Chr17:26902230 [GRCh37]
Chr17:17q11.2		 uncertain significance
NM_005165.3(ALDOC):c.451G>A (p.Val151Met) single nucleotide variant not specified [RCV004630255] Chr17:28574785 [GRCh38]
Chr17:26901803 [GRCh37]
Chr17:17q11.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2865
Count of miRNA genes:662
Interacting mature miRNAs:795
Transcripts:ENST00000226253, ENST00000395319, ENST00000395321, ENST00000435638, ENST00000460201, ENST00000578590, ENST00000581807, ENST00000582381, ENST00000584086
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298406BP16_HBlood pressure QTL 16 (human)0.0004Blood pressurehypertension susceptibility171477864740778647Human

Markers in Region
G21480  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,904,611 - 26,904,738UniSTSGRCh37
Build 361723,928,738 - 23,928,865RGDNCBI36
Celera1723,763,638 - 23,763,765RGD
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map17cen-q12UniSTS
HuRef1723,113,477 - 23,113,604UniSTS
RH102973  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,904,722 - 26,905,258UniSTSGRCh37
Build 361723,928,849 - 23,929,385RGDNCBI36
Celera1723,763,749 - 23,764,285RGD
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map17cen-q12UniSTS
HuRef1723,113,588 - 23,114,124UniSTS
ALDOC_8198  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371726,900,072 - 26,900,581UniSTSGRCh37
Build 361723,924,199 - 23,924,708RGDNCBI36
Celera1723,759,099 - 23,759,608RGD
HuRef1723,108,938 - 23,109,447UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2435 2788 2253 4974 1725 2348 6 623 1950 465 2270 7299 6469 52 3734 851 1743 1613 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_005165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005257949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011524556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054315544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC005726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF054987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK294157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC103760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC106925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC106926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF345067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT007006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GQ891338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI574194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X05196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000226253   ⟹   ENSP00000226253
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,573,120 - 28,576,895 (-)Ensembl
Ensembl Acc Id: ENST00000395319   ⟹   ENSP00000378729
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,573,115 - 28,576,885 (-)Ensembl
Ensembl Acc Id: ENST00000395321   ⟹   ENSP00000378731
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,573,115 - 28,576,948 (-)Ensembl
Ensembl Acc Id: ENST00000435638   ⟹   ENSP00000398976
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,574,788 - 28,576,398 (-)Ensembl
Ensembl Acc Id: ENST00000460201   ⟹   ENSP00000463174
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,574,696 - 28,575,914 (-)Ensembl
Ensembl Acc Id: ENST00000578590   ⟹   ENSP00000463118
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,574,964 - 28,576,424 (-)Ensembl
Ensembl Acc Id: ENST00000581807   ⟹   ENSP00000465623
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,574,714 - 28,576,894 (-)Ensembl
Ensembl Acc Id: ENST00000582381
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,574,979 - 28,576,891 (-)Ensembl
Ensembl Acc Id: ENST00000584086   ⟹   ENSP00000462674
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1728,574,710 - 28,576,895 (-)Ensembl
RefSeq Acc Id: NM_005165   ⟹   NP_005156
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,573,120 - 28,576,895 (-)NCBI
GRCh371726,900,133 - 26,904,282 (-)NCBI
Build 361723,924,260 - 23,928,078 (-)NCBI Archive
HuRef1723,108,999 - 23,112,817 (-)ENTREZGENE
CHM1_11726,961,834 - 26,965,652 (-)NCBI
T2T-CHM13v2.01729,515,745 - 29,519,520 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005257949   ⟹   XP_005258006
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,573,120 - 28,576,895 (-)NCBI
GRCh371726,900,133 - 26,904,282 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011524556   ⟹   XP_011522858
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,573,120 - 28,576,895 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054315543   ⟹   XP_054171518
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01729,515,745 - 29,519,520 (-)NCBI
RefSeq Acc Id: XM_054315544   ⟹   XP_054171519
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01729,515,745 - 29,519,520 (-)NCBI
Protein Sequences
Protein RefSeqs NP_005156 (Get FASTA)   NCBI Sequence Viewer  
  XP_005258006 (Get FASTA)   NCBI Sequence Viewer  
  XP_011522858 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171518 (Get FASTA)   NCBI Sequence Viewer  
  XP_054171519 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC09348 (Get FASTA)   NCBI Sequence Viewer  
  AAH03613 (Get FASTA)   NCBI Sequence Viewer  
  AAH65565 (Get FASTA)   NCBI Sequence Viewer  
  AAI03761 (Get FASTA)   NCBI Sequence Viewer  
  AAI06926 (Get FASTA)   NCBI Sequence Viewer  
  AAI06927 (Get FASTA)   NCBI Sequence Viewer  
  AAP35652 (Get FASTA)   NCBI Sequence Viewer  
  ADO22200 (Get FASTA)   NCBI Sequence Viewer  
  BAG35210 (Get FASTA)   NCBI Sequence Viewer  
  BAH11512 (Get FASTA)   NCBI Sequence Viewer  
  BAH11551 (Get FASTA)   NCBI Sequence Viewer  
  BAH11572 (Get FASTA)   NCBI Sequence Viewer  
  BAH11668 (Get FASTA)   NCBI Sequence Viewer  
  BAH11685 (Get FASTA)   NCBI Sequence Viewer  
  BAH12243 (Get FASTA)   NCBI Sequence Viewer  
  BAH12245 (Get FASTA)   NCBI Sequence Viewer  
  CAA28825 (Get FASTA)   NCBI Sequence Viewer  
  CAA30270 (Get FASTA)   NCBI Sequence Viewer  
  CAG46660 (Get FASTA)   NCBI Sequence Viewer  
  CAG46679 (Get FASTA)   NCBI Sequence Viewer  
  CBX47586 (Get FASTA)   NCBI Sequence Viewer  
  EAW51104 (Get FASTA)   NCBI Sequence Viewer  
  EAW51105 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000226253
  ENSP00000226253.4
  ENSP00000378729.3
  ENSP00000378731
  ENSP00000378731.2
  ENSP00000398976.1
  ENSP00000462674.1
  ENSP00000463118.1
  ENSP00000463174.2
  ENSP00000465623.1
GenBank Protein P09972 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_005156   ⟸   NM_005165
- UniProtKB: P09972 (UniProtKB/Swiss-Prot),   Q6FH94 (UniProtKB/Swiss-Prot),   Q3SYL3 (UniProtKB/Swiss-Prot),   B2R5R3 (UniProtKB/Swiss-Prot),   Q6P0L5 (UniProtKB/Swiss-Prot),   B7Z1Y2 (UniProtKB/TrEMBL),   A0A024QZ64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005258006   ⟸   XM_005257949
- Peptide Label: isoform X1
- UniProtKB: P09972 (UniProtKB/Swiss-Prot),   Q6FH94 (UniProtKB/Swiss-Prot),   Q3SYL3 (UniProtKB/Swiss-Prot),   B2R5R3 (UniProtKB/Swiss-Prot),   Q6P0L5 (UniProtKB/Swiss-Prot),   B7Z1Y2 (UniProtKB/TrEMBL),   A0A024QZ64 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011522858   ⟸   XM_011524556
- Peptide Label: isoform X1
- UniProtKB: P09972 (UniProtKB/Swiss-Prot),   Q6FH94 (UniProtKB/Swiss-Prot),   Q3SYL3 (UniProtKB/Swiss-Prot),   B2R5R3 (UniProtKB/Swiss-Prot),   Q6P0L5 (UniProtKB/Swiss-Prot),   B7Z1Y2 (UniProtKB/TrEMBL),   A0A024QZ64 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000465623   ⟸   ENST00000581807
Ensembl Acc Id: ENSP00000462674   ⟸   ENST00000584086
Ensembl Acc Id: ENSP00000463118   ⟸   ENST00000578590
Ensembl Acc Id: ENSP00000378729   ⟸   ENST00000395319
Ensembl Acc Id: ENSP00000378731   ⟸   ENST00000395321
Ensembl Acc Id: ENSP00000463174   ⟸   ENST00000460201
Ensembl Acc Id: ENSP00000398976   ⟸   ENST00000435638
Ensembl Acc Id: ENSP00000226253   ⟸   ENST00000226253
RefSeq Acc Id: XP_054171519   ⟸   XM_054315544
- Peptide Label: isoform X1
- UniProtKB: Q6FH94 (UniProtKB/Swiss-Prot),   Q3SYL3 (UniProtKB/Swiss-Prot),   P09972 (UniProtKB/Swiss-Prot),   B2R5R3 (UniProtKB/Swiss-Prot),   Q6P0L5 (UniProtKB/Swiss-Prot),   A0A024QZ64 (UniProtKB/TrEMBL),   B7Z1Y2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054171518   ⟸   XM_054315543
- Peptide Label: isoform X1
- UniProtKB: Q6FH94 (UniProtKB/Swiss-Prot),   Q3SYL3 (UniProtKB/Swiss-Prot),   P09972 (UniProtKB/Swiss-Prot),   B2R5R3 (UniProtKB/Swiss-Prot),   Q6P0L5 (UniProtKB/Swiss-Prot),   A0A024QZ64 (UniProtKB/TrEMBL),   B7Z1Y2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09972-F1-model_v2 AlphaFold P09972 1-364 view protein structure

Promoters
RGD ID:6851422
Promoter ID:EP73511
Type:multiple initiation site
Name:HS_ALDOC
Description:Aldolase C, fructose-bisphosphate.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 361723,928,040 - 23,928,100EPD
RGD ID:7234383
Promoter ID:EPDNEW_H22936
Type:initiation region
Name:ALDOC_2
Description:aldolase, fructose-bisphosphate C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22937  EPDNEW_H22938  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,574,721 - 28,574,781EPDNEW
RGD ID:7234381
Promoter ID:EPDNEW_H22937
Type:initiation region
Name:ALDOC_3
Description:aldolase, fructose-bisphosphate C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22936  EPDNEW_H22938  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,575,575 - 28,575,635EPDNEW
RGD ID:7234385
Promoter ID:EPDNEW_H22938
Type:initiation region
Name:ALDOC_1
Description:aldolase, fructose-bisphosphate C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H22937  EPDNEW_H22936  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381728,576,895 - 28,576,955EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:418 AgrOrtholog
COSMIC ALDOC COSMIC
Ensembl Genes ENSG00000109107 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000226253 ENTREZGENE
  ENST00000226253.9 UniProtKB/Swiss-Prot
  ENST00000395319.7 UniProtKB/TrEMBL
  ENST00000395321 ENTREZGENE
  ENST00000395321.6 UniProtKB/Swiss-Prot
  ENST00000435638.5 UniProtKB/TrEMBL
  ENST00000460201.6 UniProtKB/TrEMBL
  ENST00000578590.1 UniProtKB/TrEMBL
  ENST00000581807.5 UniProtKB/TrEMBL
  ENST00000584086.5 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000109107 GTEx
HGNC ID HGNC:418 ENTREZGENE
Human Proteome Map ALDOC Human Proteome Map
InterPro Aldolase_I_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldolase_TIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FBA_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 230 ENTREZGENE
OMIM 103870 OMIM
PANTHER PTHR11627 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glycolytic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA24711 PharmGKB
PROSITE ALDOLASE_CLASS_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Aldolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A024QZ64 ENTREZGENE, UniProtKB/TrEMBL
  A8MVZ9_HUMAN UniProtKB/TrEMBL
  ALDOC_HUMAN UniProtKB/Swiss-Prot
  B2R5R3 ENTREZGENE
  B7Z1Y2 ENTREZGENE, UniProtKB/TrEMBL
  C9J8F3_HUMAN UniProtKB/TrEMBL
  J3KSV6_HUMAN UniProtKB/TrEMBL
  J3QKK1_HUMAN UniProtKB/TrEMBL
  J3QKP5_HUMAN UniProtKB/TrEMBL
  K7EKH5_HUMAN UniProtKB/TrEMBL
  P09972 ENTREZGENE
  Q3SYL3 ENTREZGENE
  Q6FH94 ENTREZGENE
  Q6P0L5 ENTREZGENE
UniProt Secondary B2R5R3 UniProtKB/Swiss-Prot
  Q3SYL3 UniProtKB/Swiss-Prot
  Q6FH94 UniProtKB/Swiss-Prot
  Q6P0L5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-08 ALDOC  aldolase, fructose-bisphosphate C  ALDOC  aldolase C, fructose-bisphosphate  Symbol and/or name change 5135510 APPROVED