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Gene: Aldoc (aldolase, fructose-bisphosphate C) Chinchilla lanigera

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Symbol:

Aldoc

Name:

aldolase, fructose-bisphosphate C

RGD ID:

9008490

Description:

ENCODES a protein that exhibits cytoskeletal protein binding (ortholog); fructose-bisphosphate aldolase activity (ortholog); identical protein binding (ortholog); INVOLVED IN animal organ regeneration (ortholog); epithelial cell differentiation (ortholog); fructose 1,6-bisphosphate metabolic process (ortholog); ASSOCIATED WITH autoimmune disease of the nervous system (ortholog); borna disease (ortholog); colon adenocarcinoma (ortholog); FOUND IN axon (ortholog); postsynaptic cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

aldolase C, fructose-bisphosphate; fructose-bisphosphate aldolase C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,576,913 - 4,580,999 (+)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955481	4,576,913 - 4,580,999 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autoimmune disease of the nervous system (ISO)

borna disease (ISO)

colon adenocarcinoma (ISO)

hepatocellular carcinoma (ISO)

melanoma (ISO)

ovarian serous cystadenocarcinoma (ISO)

stroke (ISO)

Thyroid Carcinoma, Nonmedullary 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (ISO)

epithelial cell differentiation (ISO)

fructose 1,6-bisphosphate metabolic process (ISO)

gluconeogenesis (ISO)

response to hypoxia (ISO)

Cellular Component

axon (ISO)

postsynaptic cytosol (ISO)

Molecular Function

cytoskeletal protein binding (ISO)

fructose-bisphosphate aldolase activity (ISO)

identical protein binding (ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Aldoc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955481	4,576,913 - 4,580,999 (+)	Ensembl		ChiLan1.0 Ensembl
ChiLan1.0	NW_004955481	4,576,913 - 4,580,999 (+)	NCBI	ChiLan1.0	ChiLan1.0

ALDOC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	28,573,120 - 28,576,895 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	28,573,115 - 28,576,948 (-)	Ensembl		GRCh38.p14 Ensembl	hg38	GRCh38
GRCh37	17	26,900,138 - 26,903,913 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	23,924,260 - 23,928,078 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	23,924,265 - 23,927,989	NCBI
Celera	17	23,759,160 - 23,762,978 (-)	NCBI		Celera
Cytogenetic Map	17	q11.2	NCBI
HuRef	17	23,108,999 - 23,112,817 (-)	NCBI		HuRef
CHM1_1	17	26,961,834 - 26,965,652 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	29,515,745 - 29,519,520 (-)	NCBI		T2T-CHM13v2.0

Aldoc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	78,213,899 - 78,218,607 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	78,213,619 - 78,218,889 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	78,323,073 - 78,327,781 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	78,322,968 - 78,327,781 (+)	Ensembl		GRCm38.p6 Ensembl	mm10	GRCm38
MGSCv37	11	78,137,700 - 78,140,262 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	78,140,393 - 78,142,955 (+)	NCBI		MGSCv36	mm8
Celera	11	87,956,279 - 87,958,841 (+)	NCBI		Celera
Cytogenetic Map	11	B5	NCBI
cM Map	11	46.74	NCBI

Aldoc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	63,715,544 - 63,719,133 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	63,715,489 - 63,719,133 (+)	Ensembl				GRCr8
mRatBN7.2	10	63,217,477 - 63,221,066 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	63,217,451 - 63,221,066 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	67,849,778 - 67,853,367 (+)	NCBI	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	67,355,127 - 67,358,716 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	62,826,255 - 62,829,844 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	66,591,421 - 66,595,010 (+)	NCBI
Lyon_Normotensive	10	67,312,865 - 67,316,454 (+)	NCBI
Lyon_Hypertensive	10	68,986,943 - 68,990,532 (+)	NCBI
F344_StmMcwi	10	68,883,094 - 68,886,683 (+)	NCBI
Rnor_6.0	10	65,586,504 - 65,590,093 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	65,586,504 - 65,590,126 (+)	Ensembl		Rnor_6.0 Ensembl	rn6	Rnor6.0
Rnor_5.0	10	66,049,065 - 66,052,654 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	64,308,826 - 64,312,415 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	62,195,147 - 62,198,736 (+)	NCBI		Celera
RGSC_v3.1	10	64,322,448 - 64,326,038 (-)	NCBI
Cytogenetic Map	10	q25	NCBI

ALDOC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	35,883,364 - 35,887,202 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	37,763,485 - 37,767,324 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	28,198,895 - 28,202,950 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	28,702,447 - 28,706,507 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	28,700,976 - 28,706,507 (+)	Ensembl		PanPan1.1 Ensembl	panPan2	panpan1.1

ALDOC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	42,778,637 - 42,782,950 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	42,778,637 - 42,782,479 (-)	Ensembl		CanFam3.1 Ensembl	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	41,935,297 - 41,939,139 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	43,597,372 - 43,601,698 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	43,597,399 - 43,601,698 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	42,380,447 - 42,384,288 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	42,673,144 - 42,676,986 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	42,750,567 - 42,754,409 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Aldoc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mIctTri1.hap1	3	42,131,956 - 42,135,696 (-)	NCBI		mIctTri1.hap1
HiC_Itri_2	NW_024405602	41,921,047 - 41,924,788 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936538	4,798,989 - 4,802,994 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936538	4,798,991 - 4,802,700 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALDOC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	44,822,780 - 44,827,597 (-)	Ensembl		Sscrofa11.1 Ensembl	susScr11	Sscrofa11.1
Sscrofa11.1	12	44,823,376 - 44,827,273 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	46,807,780 - 46,811,676 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALDOC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mChlSab1.0.hap1	16	26,785,035 - 26,788,852 (-)	NCBI		mChlSab1.0.hap1
Vero_WHO_p1.0	NW_023666075	7,779,923 - 7,784,075 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0
ChlSab1.1	16	22,342,750 - 22,346,811 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	22,341,318 - 22,346,620 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

Aldoc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624786	1,158,270 - 1,162,801 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2
HetGla_female_1.0 Ensembl	NW_004624786	1,158,248 - 1,162,916 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl	20	48,237,453 - 48,242,545 (-)	Ensembl

Aldoc
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	92,113,149 - 92,116,780 (-)	NCBI	Rrattus_CSIRO_v1	Rrattus_CSIRO_v1

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005402747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01056944	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDI01055607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCLAT00000011676 ⟹ ENSCLAP00000011539

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955481	4,576,913 - 4,580,999 (+)	Ensembl

RefSeq Acc Id:

XM_005402747 ⟹ XP_005402804

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955481	4,576,913 - 4,580,999 (+)	NCBI

Sequence:

show sequence

CGCCCCCCGGAGAGTCACGTAGCTCTGCGGCACCCGCAGCCTCATTAACTCGAGGCGGGGCTGA
GGCGCAGCAGTTGCAGACCTGAGTCTGCGCTGCTCCTGTGGCTGCTGCTGGTAACTGGCTGCAC
ACAGAGAGCTGTCACCATGCCCCACTCATACCCAGCCCTTTCTGCTGAGCAGAAGAAGGAACTG
TCTGACATTGCTCTCCGGATTGTGGCGCCAGGGAAAGGCATTCTGGCTGCAGATGAATCTGTAG
GCAGCATGGCCAAGAGGCTGAGCCAAATCGGGGTGGAGAACACAGAGGAGAACCGCCGGCTGTA
CCGCCAGGTCCTGTTCAGCGCTGATGACCGTGTGAAGAAGTGCATTGGCGGCGTCATCTTCTTC
CATGAGACACTCTACCAGAAAGATGATAACGGTGTCCCCTTTGTGCGAACCATCCAGGATAAGG
GCATTGTCGTGGGCATCAAGGTTGACAAGGGTGTAGTGCCTCTGGCTGGGACGGATGGAGAAAC
CACCACTCAAGGGCTGGATGGGCTGTCTGAACGCTGTGCTCAGTACAAGAAAGATGGCGCTGAC
TTTGCCAAATGGCGCTGCGTGCTGAAAATCAGTGAGCGCACACCCTCAGCGCTCGCCATCCTGG
AGAATGCCAATGTGCTGGCCCGCTATGCCAGCATCTGTCAGCAGAATGGCATTGTTCCTATTGT
GGAGCCTGAGATCCTGCCTGATGGAGACCATGATCTCAAACGTTGCCAGTATGTTACAGAAAAG
GTCCTGGCTGCTGTGTACAAGGCCCTGAGTGATCACCATGTGTACCTGGAGGGGACTCTGCTTA
AGCCCAACATGGTGACCCCTGGCCATGCCTGTCCCATCAAGTACAGCCCAGAGGAGATTGCCAT
GGCCACCGTCACTGCCCTGCGTCGCACTGTGCCCCCAGCTGTCCCAGGGGTGACCTTCCTGTCC
GGGGGTCAGAGTGAAGAGGAGGCCTCACTCAACCTCAATGCCATCAATCGCTGTCCCCTTCCGC
GGCCGTGGGCCCTCACCTTCTCCTATGGGCGTGCCCTGCAGGCCTCTGCACTCAATGCCTGGCG
AGGGCAAAAGGACAATGCTGGAGCTGCCACTGAAGAGTTCATCAAGCGGGCTGAGGTGAATGGG
CTTGCAGCCCAGGGCAAGTATGAAGGCAGTGGAGAAGACGGCGGAGCAGCGGCGCAGTCCCTCT
ATATTGCAAACCATGCCTACTGAGGAGTGCTTACTCCACACTACCGCCCTTGGCCCAGCCATCT
GCACCTACTTTGCCTGTAGTCACGGCCAGGGTCAAATAGCCATGCAGAACAGAGATGCCTTCAC
CCAGCCCCAAGTCCTTGTCTTTTTCTCTTCTCCCCTCTCCTCTCCCATTGCTGCACCTGGGACC
ACAGGACGGGAGAATAGGAAGCCCCTCAGGTCTGAGGGCAGGAGAGTGGCTAGAAATCAGAGCA
GGATGCCTGGGTATTCCTCAGTCTCCCCAGCCCTCATAATTTCCCCATGATGGTACAGCTTCTC
CTTGGGCTATCGTTGCTGGCCCTTGCTCTAGGATGAGAAGGAAGTATATAAGCCCCGACTCATG
CCTTGAGTATATACCATATAGGAAATAAAAGGTAGCAAAACATGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005402804	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000011539
	ENSCLAP00000011539.1

RefSeq Acc Id:

XP_005402804 ⟸ XM_005402747

- UniProtKB:

A0A8C2VA03 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPHSYPALSAEQKKELSDIALRIVAPGKGILAADESVGSMAKRLSQIGVENTEENRRLYRQVLF
SADDRVKKCIGGVIFFHETLYQKDDNGVPFVRTIQDKGIVVGIKVDKGVVPLAGTDGETTTQGL
DGLSERCAQYKKDGADFAKWRCVLKISERTPSALAILENANVLARYASICQQNGIVPIVEPEIL
PDGDHDLKRCQYVTEKVLAAVYKALSDHHVYLEGTLLKPNMVTPGHACPIKYSPEEIAMATVTA
LRRTVPPAVPGVTFLSGGQSEEEASLNLNAINRCPLPRPWALTFSYGRALQASALNAWRGQKDN
AGAATEEFIKRAEVNGLAAQGKYEGSGEDGGAAAQSLYIANHAY

hide sequence

Ensembl Acc Id:

ENSCLAP00000011539 ⟸ ENSCLAT00000011676

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000007956	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000011676	ENTREZGENE
	ENSCLAT00000011676.1	UniProtKB/TrEMBL
Gene3D-CATH	3.20.20.70	UniProtKB/TrEMBL
InterPro	Aldolase_I_AS	UniProtKB/TrEMBL
	Aldolase_TIM	UniProtKB/TrEMBL
	FBA_I	UniProtKB/TrEMBL
NCBI Gene	Aldoc	ENTREZGENE
PANTHER	PTHR11627	UniProtKB/TrEMBL
Pfam	Glycolytic	UniProtKB/TrEMBL
PROSITE	ALDOLASE_CLASS_I	UniProtKB/TrEMBL
Superfamily-SCOP	Aldolase	UniProtKB/TrEMBL
UniProt	A0A8C2VA03	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-08-16	Aldoc	aldolase, fructose-bisphosphate C		aldolase C, fructose-bisphosphate	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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