Aldoart2 (aldolase 1 A, retrogene 2) - Rat Genome Database

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Gene: Aldoart2 (aldolase 1 A, retrogene 2) Mus musculus
Analyze
Symbol: Aldoart2
Name: aldolase 1 A, retrogene 2
RGD ID: 1623093
MGI Page MGI
Description: Predicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to be active in cytosol. Is expressed in alimentary system; eye; nervous system; and trunk.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 4933425L11Rik; Ald; Aldo; Aldo1-ps1; Aldoa-ps1; aldolase 1 A retrogene 2; aldolase 1, a isoform, pseudogene 1; aldolase A retroprotein 2; fructose-bisphosphate aldolase A-like
RGD Orthologs
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,611,990 - 55,613,681 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,612,024 - 55,613,681 (+)EnsemblGRCm39 Ensembl
GRCm381255,565,205 - 55,566,896 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,565,239 - 55,566,896 (+)EnsemblGRCm38mm10GRCm38
MGSCv371256,666,122 - 56,667,696 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361256,483,685 - 56,484,179 (+)NCBIMGSCv36mm8
Celera1256,714,814 - 56,716,388 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1224.04NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11221845   PMID:11504845   PMID:12466851   PMID:16141072   PMID:16141073   PMID:17659271   PMID:21267068   PMID:21873635  
PMID:22673621  


Genomics

Comparative Map Data
Aldoart2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391255,611,990 - 55,613,681 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1255,612,024 - 55,613,681 (+)EnsemblGRCm39 Ensembl
GRCm381255,565,205 - 55,566,896 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1255,565,239 - 55,566,896 (+)EnsemblGRCm38mm10GRCm38
MGSCv371256,666,122 - 56,667,696 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361256,483,685 - 56,484,179 (+)NCBIMGSCv36mm8
Celera1256,714,814 - 56,716,388 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1224.04NCBI
Aldoart2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8678,674,945 - 78,676,635 (+)NCBIGRCr8
mRatBN7.2672,939,821 - 72,941,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl672,939,788 - 72,941,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx673,361,318 - 73,363,008 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0673,667,686 - 73,669,376 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0673,095,184 - 73,096,873 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0676,349,362 - 76,351,052 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl676,349,362 - 76,351,051 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0685,883,180 - 85,884,870 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4675,812,016 - 75,813,706 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1675,815,141 - 75,816,831 (+)NCBI
Celera671,781,674 - 71,783,364 (+)NCBICelera
Cytogenetic Map6q23NCBI

Variants

.
Variants in Aldoart2
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:171
Count of miRNA genes:143
Interacting mature miRNAs:159
Transcripts:ENSMUST00000080123
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12541844077031203Mouse
27226753Femd7_mfemur midshaft diameter 7, 10 week (mouse)12955000084146774Mouse
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121166000197176774Mouse
1558978Cplaq10_mcircadian period of locomotor activity 10 (mouse)Not determined121534102679040364Mouse
1301574Lmblgq5_mlimb length QTL 5 (mouse)Not determined121759644780956883Mouse
1302172Skts5_mskin tumor susceptibility 5 (mouse)Not determined122214886656149016Mouse
1301989Hdlq18_mHDL QTL 18 (mouse)Not determined122916068563160884Mouse
1300636Gct2_mgranulosa cell tumorigenesis 2 (mouse)Not determined122916068563160884Mouse
4141843Moen3_mmodifier of engrailed QTL 3 (mouse)Not determined122980158463801733Mouse
14747008Mancz10_mmandible centroid size 10 (mouse)122986352263863522Mouse
10402492Dipa8_mdrug induced psychomotor activation 8 (mouse)Not determined123493387268934019Mouse
1300818Bbaa10_mB.burgdorferi-associated arthritis 10 (mouse)Not determined123509100465511019Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235285496109936243Mouse
1357479Splwt1_mspleen weight 1 (mouse)Not determined124169317590887526Mouse
1357757Lnopy2_mlens opacity 2 (mouse)Not determined125284662686846796Mouse
1357749Vtbt13_mvertebral trabecular bone trait 13 (mouse)Not determined125313200287132145Mouse
12904004Opfaq11_mopen field activity QTL 11 (mouse)125315562457276756Mouse
12832727Ahrq1_mairway hyperresponsiveness QTL 1 (mouse)125469591082665939Mouse
12903999Opfaq8_mopen field activity QTL 8 (mouse)125490765357870585Mouse


Expression


Sequence


RefSeq Acc Id: ENSMUST00000080123   ⟹   ENSMUSP00000079022
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1255,612,024 - 55,613,681 (+)Ensembl
GRCm38.p6 Ensembl1255,565,239 - 55,566,896 (+)Ensembl
RefSeq Acc Id: NM_001277340   ⟹   NP_001264269
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391255,611,990 - 55,613,681 (+)NCBI
GRCm381255,565,205 - 55,566,896 (+)NCBI
Celera1256,714,884 - 56,716,575 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001264269 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABR88098 (Get FASTA)   NCBI Sequence Viewer  
  BAB24582 (Get FASTA)   NCBI Sequence Viewer  
  BAB30498 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000079022
  ENSMUSP00000079022.2
RefSeq Acc Id: NP_001264269   ⟸   NM_001277340
- UniProtKB: A6ZI47 (UniProtKB/TrEMBL),   Q6NY00 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000079022   ⟸   ENSMUST00000080123

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A6ZI47-F1-model_v2 AlphaFold A6ZI47 1-364 view protein structure

Promoters
RGD ID:8678300
Promoter ID:EPDNEW_M17181
Type:initiation region
Name:Aldoart2_1
Description:Mus musculus aldolase 1 A, retrogene 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381255,565,297 - 55,565,357EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1931052 AgrOrtholog
Ensembl Genes ENSMUSG00000063129 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000080123 ENTREZGENE
  ENSMUST00000080123.2 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
InterPro Aldolase_I UniProtKB/TrEMBL
  Aldolase_I_AS UniProtKB/TrEMBL
  Aldolase_TIM UniProtKB/TrEMBL
KEGG Report mmu:79459 UniProtKB/TrEMBL
MGD MGI:1931052 ENTREZGENE
NCBI Gene 79459 ENTREZGENE
PANTHER FRUCTOSE-BISPHOSPHATE ALDOLASE UniProtKB/TrEMBL
  FRUCTOSE-BISPHOSPHATE ALDOLASE A UniProtKB/TrEMBL
  PTHR11627 UniProtKB/TrEMBL
Pfam Glycolytic UniProtKB/TrEMBL
PhenoGen Aldoart2 PhenoGen
PROSITE ALDOLASE_CLASS_I UniProtKB/TrEMBL
Superfamily-SCOP Aldolase UniProtKB/TrEMBL
UniProt A6ZI47 ENTREZGENE, UniProtKB/TrEMBL
  Q6NY00 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-13 Aldoart2  aldolase 1 A, retrogene 2    aldolase 1 A retrogene 2  Symbol and/or name change 5135510 APPROVED
2011-07-27 Aldoart2  aldolase 1 A retrogene 2  Aldoart2  aldolase 1, A isoform, retrogene 2  Symbol and/or name change 5135510 APPROVED