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Gene: CSTB (cystatin B) Homo sapiens
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Symbol: CSTB
Name: cystatin B
Description: Exhibits cysteine-type endopeptidase inhibitor activity and protease binding activity. Involved in negative regulation of peptidase activity. Localizes to cytosol; extracellular space; and nucleolus. Implicated in Unverricht-Lundborg syndrome and progressive myoclonus epilepsy 1A.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CPI-B; CST6; cystatin B (stefin B); cystatin-B; EPM1; EPM1A; liver thiol proteinase inhibitor; PME; stefin B; stefin-B; STFB; ULD
Orthologs:
Mus musculus (house mouse) : Cstb (cystatin B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cstb (cystatin B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cstb (cystatin B)
Pan paniscus (bonobo/pygmy chimpanzee) : CSTB (cystatin B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cstb (cystatin B)
Sus scrofa (pig) : CSTB (cystatin B)
Chlorocebus sabaeus (African green monkey) : CSTB (cystatin B)
Heterocephalus glaber (naked mole-rat) : Cstb (cystatin B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2143,772,511 - 43,776,445 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl2143,772,511 - 43,776,318 (-)EnsemblGRCh38hg38GRCh38
GRCh382143,773,950 - 43,776,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372145,193,546 - 45,196,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,018,259 - 44,020,687 (-)NCBINCBI36hg18NCBI36
Build 342144,018,259 - 44,020,687NCBI
Celera2130,299,423 - 30,301,851 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2130,561,944 - 30,564,654 (-)NCBIHuRef
CHM1_12144,754,030 - 44,756,740 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CSTB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735434
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.