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Gene: TCFL5 (transcription factor like 5) Homo sapiens
Symbol: TCFL5
Name: transcription factor like 5
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; regulation of cell population proliferation; and spermatogenesis. Localizes to the nucleus; INTERACTS WITH 2-methylcholine; all-trans-retinoic acid; antirheumatic drug.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bHLHe82; CHA; cha transcription factor; E2BP-1; Figlb; HPV-16 E2 binding protein 1; HPV-16 E2-binding protein 1; MGC46135; SOSF1; spermatogenesis- and oogenesis-specific bHLH-containing protein 1; transcription factor-like 5 (basic helix-loop-helix); transcription factor-like 5 protein
Mus musculus (house mouse) : Tcfl5 (transcription factor-like 5 (basic helix-loop-helix))  MGI  Alliance
Rattus norvegicus (Norway rat) : Tcfl5 (transcription factor like 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcfl5 (transcription factor like 5)
Pan paniscus (bonobo/pygmy chimpanzee) : TCFL5 (transcription factor like 5)
Canis lupus familiaris (dog) : TCFL5 (transcription factor like 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcfl5 (transcription factor like 5)
Sus scrofa (pig) : TCFL5 (transcription factor like 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382062,841,005 - 62,861,822 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372061,472,467 - 61,493,115 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362060,942,912 - 60,963,560 (-)NCBINCBI36hg18NCBI36
Build 342060,942,912 - 60,963,560NCBI
Celera2058,148,498 - 58,169,147 (-)NCBI
Cytogenetic Map20q13.33NCBI
HuRef2058,190,512 - 58,209,710 (-)NCBIHuRef
CHM1_12061,373,283 - 61,393,975 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TCFL5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348705
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.