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Gene: BEX3 (brain expressed X-linked 3) Homo sapiens
Symbol: BEX3
Name: brain expressed X-linked 3
Description: Exhibits identical protein binding activity. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process; multicellular organism development; and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process. Localizes to cytosol; PARTICIPATES IN neurotrophic factor signaling pathway; INTERACTS WITH 17beta-estradiol; 2-methylcholine; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bex; brain expressed, X-linked 3; brain-expressed X-linked protein 3; DXS6984E; HGR74; NADE; nerve growth factor receptor (TNFRSF16) associated protein 1; nerve growth factor receptor-associated protein 1; NGFRAP1; ovarian granulosa cell 13.0 kDa protein HGR74; ovarian granulosa cell protein (13kD); p75NTR-associated cell death executor
Mus musculus (house mouse) : Bex3 (brain expressed X-linked 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bex3 (brain expressed X-linked 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bex3 (brain expressed X-linked 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BEX3 (brain expressed X-linked 3)
Canis lupus familiaris (dog) : BEX3 (brain expressed X-linked 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bex3 (brain expressed X-linked 3)
Sus scrofa (pig) : BEX3 (brain expressed X-linked 3)
Chlorocebus sabaeus (African green monkey) : BEX3 (brain expressed X-linked 3)
Heterocephalus glaber (naked mole-rat) : Bex3 (brain expressed X-linked 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX103,376,395 - 103,378,164 (+)EnsemblGRCh38hg38GRCh38
GRCh38 EnsemblX103,376,340 - 103,378,077 (+)EnsemblGRCh38hg38GRCh38
GRCh38X103,376,323 - 103,378,164 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X102,631,268 - 102,633,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X102,517,924 - 102,519,657 (+)NCBINCBI36hg18NCBI36
Build 34X102,438,253 - 102,439,144NCBI
CeleraX103,070,266 - 103,071,999 (+)NCBI
Cytogenetic MapXq22.2NCBI
HuRefX92,293,489 - 92,296,152 (+)NCBIHuRef
CHM1_1X102,524,254 - 102,526,095 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BEX3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735398
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.