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Gene: GABRG3 (gamma-aminobutyric acid type A receptor gamma3 subunit) Homo sapiens
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Symbol: GABRG3
Name: gamma-aminobutyric acid type A receptor gamma3 subunit
Description: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GABA(A) receptor subunit gamma-3; GABA(G) receptor, gamma 3; gamma-aminobutyric acid (GABA) A receptor, gamma 3; gamma-aminobutyric acid receptor subunit gamma-3
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381526,971,181 - 27,541,984 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371527,216,429 - 27,778,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361524,799,263 - 25,168,899 (+)NCBINCBI36hg18NCBI36
Build 361525,399,391 - 25,451,729 (+)NCBINCBI36hg18NCBI36
Build 341525,399,390 - 25,451,722NCBI
Celera155,377,602 - 5,938,310 (+)NCBI
Cytogenetic Map15q12NCBI
HuRef155,344,440 - 5,905,082 (+)NCBIHuRef
CHM1_11527,165,969 - 27,727,967 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on GABRG3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733632
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.