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Gene: GABRG3 (gamma-aminobutyric acid type A receptor gamma3 subunit) Homo sapiens
Symbol: GABRG3
Name: gamma-aminobutyric acid type A receptor gamma3 subunit
Description: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GABA(A) receptor subunit gamma-3; GABA(G) receptor, gamma 3; gamma-aminobutyric acid (GABA) A receptor, gamma 3; gamma-aminobutyric acid receptor subunit gamma-3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381526,971,181 - 27,541,984 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371527,216,429 - 27,778,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361524,799,263 - 25,168,899 (+)NCBINCBI36hg18NCBI36
Build 361525,399,391 - 25,451,729 (+)NCBINCBI36hg18NCBI36
Build 341525,399,390 - 25,451,722NCBI
Celera155,377,602 - 5,938,310 (+)NCBI
Cytogenetic Map15q12NCBI
HuRef155,344,440 - 5,905,082 (+)NCBIHuRef
CHM1_11527,165,969 - 27,727,967 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GABRG3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733632
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.