Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ACLY (ATP citrate lyase) Homo sapiens
Analyze
Symbol: ACLY
Name: ATP citrate lyase
Description: Exhibits ATP citrate synthase activity. Involved in acetyl-CoA biosynthetic process; carboxylic acid metabolic process; and lipid biosynthetic process. Localizes to cytosol; nucleoplasm; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ACL; ATP citrate synthase; ATP-citrate (pro-S-)-lyase; ATP-citrate synthase; ATPCL; citrate cleavage enzyme; CLATP
Orthologs:
Mus musculus (house mouse) : Acly (ATP citrate lyase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acly (ATP citrate lyase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acly (ATP citrate lyase)
Pan paniscus (bonobo/pygmy chimpanzee) : ACLY (ATP citrate lyase)
Canis lupus familiaris (dog) : ACLY (ATP citrate lyase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acly (ATP citrate lyase)
Sus scrofa (pig) : ACLY (ATP citrate lyase)
Chlorocebus sabaeus (African green monkey) : ACLY (ATP citrate lyase)
Heterocephalus glaber (naked mole-rat) : Acly (ATP citrate lyase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1741,866,917 - 41,930,542 (-)EnsemblGRCh38hg38GRCh38
GRCh381741,866,916 - 41,930,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371740,023,169 - 40,086,795 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,276,705 - 37,328,798 (-)NCBINCBI36hg18NCBI36
Build 341737,276,706 - 37,328,798NCBI
Celera1736,674,340 - 36,725,809 (-)NCBI
Cytogenetic Map17q21.2NCBI
HuRef1735,785,140 - 35,836,956 (-)NCBIHuRef
CHM1_11740,258,585 - 40,311,003 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ACLY
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10065
Created: 2000-05-25
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.