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Gene: PTPRR (protein tyrosine phosphatase receptor type R) Homo sapiens
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Symbol: PTPRR
Name: protein tyrosine phosphatase receptor type R
Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Ch-1 PTPase; ch-1PTPase; DKFZp781C1038; EC-PTP; FLJ34328; MGC131968; MGC148170; NC-PTPCOM1; PCPTP1; protein tyrosine phosphatase Cr1PTPase; protein-tyrosine phosphatase NC-PTPCOM1; protein-tyrosine phosphatase PCPTP1; PTP-SL; PTPBR7; PTPRQ; R-PTP-R; receptor-type tyrosine-protein phosphatase R
Orthologs:
Mus musculus (house mouse) : Ptprr (protein tyrosine phosphatase, receptor type, R)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ptprr (protein tyrosine phosphatase, receptor type, R)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprr (protein tyrosine phosphatase receptor type R)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRR (protein tyrosine phosphatase receptor type R)
Canis lupus familiaris (dog) : PTPRR (protein tyrosine phosphatase receptor type R)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101964395 (receptor-type tyrosine-protein phosphatase R)
Sus scrofa (pig) : PTPRR (protein tyrosine phosphatase receptor type R)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381270,638,073 - 70,920,804 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371271,031,853 - 71,314,584 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361269,318,129 - 69,600,853 (-)NCBINCBI36hg18NCBI36
Build 341269,318,128 - 69,434,632NCBI
Celera1270,695,535 - 70,977,822 (-)NCBI
Cytogenetic Map12q15NCBI
HuRef1268,081,248 - 68,364,028 (-)NCBIHuRef
CHM1_11271,001,121 - 71,283,977 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Nucleotide Sequences
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Nomenclature History
 
More on PTPRR
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1348456
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-07-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.